Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers

Journal of Biological Chemistry

Volumn 287, Issue 12, 2012, Pages 9222-9229

  Kasiviswanathan, Rajesh ^a   Gustafson, Margaret A ^b   Copeland, William C ^a   Meyer, Joel N ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOBUTANE-THYMINE DIMERS; DNA DAMAGES; DNA POLYMERASE; DNA POLYMERIZATION; HIGHER EFFICIENCY; HUMAN MITOCHONDRIAL DNA POLYMERASE; IN-VITRO; MITOCHONDRIAL DNA; MITOCHONDRIAL GENOMES; NUCLEOTIDE EXCISION REPAIR; POINT MUTATIONS; RELATIVE EFFICIENCY; SHORT WAVELENGTHS; THYMINE DIMERS; TRANSLESION;

BUTANE; DIMERS; MITOCHONDRIA; NUCLEOTIDES; POLYMERS; POSITIVE IONS; ULTRAVIOLET RADIATION;

DNA;

CYCLOBUTANE DERIVATIVE; CYCLOBUTANE THYMINE DIMER; DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA; THYMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANISOTROPY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA REPLICATION; ENZYME SPECIFICITY; EXCISION REPAIR; IN VITRO STUDY; MITOCHONDRIAL GENOME; MUTAGENESIS; NONHUMAN; POINT MUTATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING;

CYCLOBUTANES; DIMERIZATION; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HUMANS; KINETICS; MITOCHONDRIA; MUTAGENESIS; THYMINE; ULTRAVIOLET RAYS;

EID: 84863393097     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.306852     Document Type: Article

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