메뉴 건너뛰기




Volumn 277, Issue 3 PART 1, 1999, Pages

Osteocyte hypoxia: A novel mechanotransduction pathway

Author keywords

Bone adaptation; Bone loss; Disuse; Oxygen metabolism

Indexed keywords

ANIMAL CELL; ARTICLE; BONE ATROPHY; CELL HYPOXIA; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; MECHANICAL STRESS; NONHUMAN; OSTEOCYTE; OSTEOPENIA; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TURKEY (BIRD); ULNA; WEIGHT BEARING;

EID: 0032852497     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1999.277.3.c598     Document Type: Article
Times cited : (107)

References (30)
  • 1
    • 0025080230 scopus 로고
    • Growth regulation of the vascular system: Evidence for a metabolic hypothesis
    • Regulatory Integrative Comp. Physiol. 28
    • Adair, T. H., W. J. Gay, and J. P. Montani. Growth regulation of the vascular system: evidence for a metabolic hypothesis. Am. J. Physiol. 259 (Regulatory Integrative Comp. Physiol. 28): R393-R404, 1990.
    • (1990) Am. J. Physiol. , vol.259
    • Adair, T.H.1    Gay, W.J.2    Montani, J.P.3
  • 2
    • 0031194630 scopus 로고    scopus 로고
    • Testing the daily stress stimulus theory of bone adaptation with natural and experimentally controlled strain histories
    • Adams, D. J., A. A. Spirt, T. D. Brown, S. P. Fritton, C. T. Rubin, and R. A. Brand. Testing the daily stress stimulus theory of bone adaptation with natural and experimentally controlled strain histories. J. Biomech. 30: 671-678, 1997.
    • (1997) J. Biomech. , vol.30 , pp. 671-678
    • Adams, D.J.1    Spirt, A.A.2    Brown, T.D.3    Fritton, S.P.4    Rubin, C.T.5    Brand, R.A.6
  • 3
    • 0028785458 scopus 로고
    • Evidence that hypoxia markers detect oxygen gradients in liver: Pimonidazole and retrograde perfusion of rat liver
    • Arteel, G. E., R. G. Thurman, J. M. Yates, and J. A. Raleigh. Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. Br. J. Cancer 72: 889-895, 1995.
    • (1995) Br. J. Cancer , vol.72 , pp. 889-895
    • Arteel, G.E.1    Thurman, R.G.2    Yates, J.M.3    Raleigh, J.A.4
  • 4
    • 0030307230 scopus 로고    scopus 로고
    • Induced hypoxia in rat pulp and periapex demonstrated by 3H-misonidazole retention
    • Baumgardner, K. R., R. E. Walton, J. W. Osborne, and J. L. Born. Induced hypoxia in rat pulp and periapex demonstrated by 3H-misonidazole retention. Dent. Res. 75: 1753-1760, 1996.
    • (1996) Dent. Res. , vol.75 , pp. 1753-1760
    • Baumgardner, K.R.1    Walton, R.E.2    Osborne, J.W.3    Born, J.L.4
  • 6
    • 0026320527 scopus 로고
    • Effect of oxygen deprivation on the excitability of isolated hippocampal CA1 neurons: Developmental aspects
    • Cummins, T. R., D. F. Donnelly, and G. G. Haddad. Effect of oxygen deprivation on the excitability of isolated hippocampal CA1 neurons: developmental aspects. J. Neurophysiol. 66: 1471-1482, 1991.
    • (1991) J. Neurophysiol. , vol.66 , pp. 1471-1482
    • Cummins, T.R.1    Donnelly, D.F.2    Haddad, G.G.3
  • 8
    • 0019774348 scopus 로고
    • Morphological evidence of gap junctions between bone cells
    • Doty, S. B. Morphological evidence of gap junctions between bone cells. Calcif. Tissue Int. 33: 509-512, 1981.
    • (1981) Calcif. Tissue Int. , vol.33 , pp. 509-512
    • Doty, S.B.1
  • 9
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber, T. G., C. Osmanian, T. Jacks, D. E. Housman, C. J. Koch, S. W. Lowe, and A. J. Giaccia. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 379: 88-91, 1996.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3    Housman, D.E.4    Koch, C.J.5    Lowe, S.W.6    Giaccia, A.J.7
  • 10
    • 0032930070 scopus 로고    scopus 로고
    • Bone hyperemia precedes disuse induced intracortical bone resorption
    • Gross, T. S., A. A. Damji, S. Judex, R. C. Bray, and R. F. Zernicke. Bone hyperemia precedes disuse induced intracortical bone resorption. J. Appl. Physiol. 86: 230-235, 1999.
    • (1999) J. Appl. Physiol. , vol.86 , pp. 230-235
    • Gross, T.S.1    Damji, A.A.2    Judex, S.3    Bray, R.C.4    Zernicke, R.F.5
  • 11
    • 0031992096 scopus 로고    scopus 로고
    • Arabidopsis thaliana responses to mechanical stimulation do not require ETR1 or EIN2
    • Johnson, K. A., M. L. Sistrunk, D. H. Polisensky, and J. Braam. Arabidopsis thaliana responses to mechanical stimulation do not require ETR1 or EIN2. Plant Physiol. 116: 643-649, 1998.
    • (1998) Plant Physiol. , vol.116 , pp. 643-649
    • Johnson, K.A.1    Sistrunk, M.L.2    Polisensky, D.H.3    Braam, J.4
  • 12
    • 0032546451 scopus 로고    scopus 로고
    • Mechanotransduction in stretched osteocytes-temporal expression of immediate early and other genes
    • Kawata, A., and Y. Mikuni-Takagaki. Mechanotransduction in stretched osteocytes-temporal expression of immediate early and other genes. Biochem. Biophys. Res. Commun. 246: 404-408, 1998.
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , pp. 404-408
    • Kawata, A.1    Mikuni-Takagaki, Y.2
  • 13
    • 0027489236 scopus 로고
    • The influence of irradiation of the tumor bed on tumor hypoxia: Measurements by radiation response, oxygen electrodes, and nitroimidazole binding
    • Kim, I. H., M. J. Lemmon, and J. M. Brown. The influence of irradiation of the tumor bed on tumor hypoxia: measurements by radiation response, oxygen electrodes, and nitroimidazole binding. Radiat. Res. 135: 411-417, 1993.
    • (1993) Radiat. Res. , vol.135 , pp. 411-417
    • Kim, I.H.1    Lemmon, M.J.2    Brown, J.M.3
  • 14
    • 0030000861 scopus 로고    scopus 로고
    • Sequence and transmembrane topology of MEC-4, an ion channel subunit required for mechanotransduction in Caenorhabditis elegans
    • Lai, C. C., K. Hong, M. Kinnell, M. Chalfie, and M. Driscoll. Sequence and transmembrane topology of MEC-4, an ion channel subunit required for mechanotransduction in Caenorhabditis elegans. J. Cell Biol. 133: 1071-1081, 1996.
    • (1996) J. Cell Biol. , vol.133 , pp. 1071-1081
    • Lai, C.C.1    Hong, K.2    Kinnell, M.3    Chalfie, M.4    Driscoll, M.5
  • 15
    • 0024604966 scopus 로고
    • The effect of hypobaric hypoxia on misonidazole binding in normal and tumour-bearing mice
    • MacManus, W. P., A. P. Maxwell, W. P. Abram, and J. M. Bridges. The effect of hypobaric hypoxia on misonidazole binding in normal and tumour-bearing mice. Br. J. Cancer 59: 349-352, 1988.
    • (1988) Br. J. Cancer , vol.59 , pp. 349-352
    • MacManus, W.P.1    Maxwell, A.P.2    Abram, W.P.3    Bridges, J.M.4
  • 16
    • 0017642753 scopus 로고
    • The cellular basis of bone turnover and bone loss: A rebuttal of the osteocytic resorption-bone flow theory
    • Parfitt, A. M. The cellular basis of bone turnover and bone loss: a rebuttal of the osteocytic resorption-bone flow theory. Clin. Orthop. 127: 236-247, 1977.
    • (1977) Clin. Orthop. , vol.127 , pp. 236-247
    • Parfitt, A.M.1
  • 17
    • 0017654342 scopus 로고
    • Transport mechanism operating between blood supply and osteocytes in long bones
    • Piekarski, K., and M. Munro. Transport mechanism operating between blood supply and osteocytes in long bones. Nature 269: 80-82, 1977.
    • (1977) Nature , vol.269 , pp. 80-82
    • Piekarski, K.1    Munro, M.2
  • 19
    • 0031909665 scopus 로고    scopus 로고
    • Role of morphogenetic proteins in skeletal tissue engineering and regeneration
    • Reddi, A. H. Role of morphogenetic proteins in skeletal tissue engineering and regeneration. Nat. Biotechnol. 16: 247-252, 1998.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 247-252
    • Reddi, A.H.1
  • 20
    • 0029859197 scopus 로고    scopus 로고
    • Differentiation of the bone-tissue remodeling response to axial and torsional loading in the turkey ulna
    • Rubin, C. T., T. Gross, Y.-X. Qin, S. Fritton, F. Guilak, and K. McLeod. Differentiation of the bone-tissue remodeling response to axial and torsional loading in the turkey ulna. J. Bone Joint Surg. Am. 78: 1523-1533, 1996.
    • (1996) J. Bone Joint Surg. Am. , vol.78 , pp. 1523-1533
    • Rubin, C.T.1    Gross, T.2    Qin, Y.-X.3    Fritton, S.4    Guilak, F.5    McLeod, K.6
  • 21
    • 0021322767 scopus 로고
    • Regulation of bone formation by applied dynamic loads
    • Rubin, C. T., and L. E. Lanyon. Regulation of bone formation by applied dynamic loads. J. Bone Joint Surg. Am. 66: 397-402, 1984.
    • (1984) J. Bone Joint Surg. Am. , vol.66 , pp. 397-402
    • Rubin, C.T.1    Lanyon, L.E.2
  • 22
    • 0030961593 scopus 로고    scopus 로고
    • Chondrocytes in the endochondral growth cartilage are not hypoxic
    • Cell Physiol. 41
    • Shapiro, I. M., K. D. Mansfield, S. M. Evans, E. M. Lord, and C. J. Koch. Chondrocytes in the endochondral growth cartilage are not hypoxic. Am. J. Physiol. 272 (Cell Physiol. 41): C1134-C1143, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Shapiro, I.M.1    Mansfield, K.D.2    Evans, S.M.3    Lord, E.M.4    Koch, C.J.5
  • 23
    • 0024326174 scopus 로고
    • Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo
    • Skerry, T. M., L. Bitensky, J. Chayen, and L. E. Lanyon. Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo. J. Bone Miner. Res. 4: 783-788, 1989.
    • (1989) J. Bone Miner. Res. , vol.4 , pp. 783-788
    • Skerry, T.M.1    Bitensky, L.2    Chayen, J.3    Lanyon, L.E.4
  • 24
    • 0028826051 scopus 로고
    • Mechanically induced periosteal bone formation is paralleled by the upregulation of collagen type one mRNA in osteocytes as measured by in situ reverse transcript-polymerase chain reaction
    • Sun, Y. Q., K. J. McLeod, and C. T. Rubin. Mechanically induced periosteal bone formation is paralleled by the upregulation of collagen type one mRNA in osteocytes as measured by in situ reverse transcript-polymerase chain reaction. Calcif. Tissue Int. 57: 456-462, 1995.
    • (1995) Calcif. Tissue Int. , vol.57 , pp. 456-462
    • Sun, Y.Q.1    McLeod, K.J.2    Rubin, C.T.3
  • 25
    • 0031975298 scopus 로고    scopus 로고
    • In vivo tracer transport through the lacunocanalicular system of rat bone in an environment devoid of mechanical loading
    • Tate, M. L., P. Niederer, and U. Knothe. In vivo tracer transport through the lacunocanalicular system of rat bone in an environment devoid of mechanical loading. Bone 22: 107-117, 1998.
    • (1998) Bone , vol.22 , pp. 107-117
    • Tate, M.L.1    Niederer, P.2    Knothe, U.3
  • 26
    • 0030884639 scopus 로고    scopus 로고
    • The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone
    • Tomkinson, A., J. Reeve, R. W. Shaw, and B. S. Noble. The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone. J. Clin. Endocrinol. Metab. 82: 3128-3135, 1997.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 3128-3135
    • Tomkinson, A.1    Reeve, J.2    Shaw, R.W.3    Noble, B.S.4
  • 28
    • 0024443967 scopus 로고
    • Effects of hypoxia on cyclic nucleotide formation in rabbit carotid body in vitro
    • Wang, W. J., G. F. Cheng, B. G. Dinger, and S. J. Fidone. Effects of hypoxia on cyclic nucleotide formation in rabbit carotid body in vitro. Neurosci. Lett. 105: 164-168, 1989.
    • (1989) Neurosci. Lett. , vol.105 , pp. 164-168
    • Wang, W.J.1    Cheng, G.F.2    Dinger, B.G.3    Fidone, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.