The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 23128-23140

  Baljuls, Angela ^a   Beck, Matthias ^c   Oenel, Ayla ^a   Robubi, Armin ^b   Kroschewski, Ruth ^c   Hekman, Mirko ^a   Rudel, Thomas ^a   Rapp, Ulf R ^a,d  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c ETH ZURICH   (Switzerland)

^d MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; BREAST CANCER; CANCER CELLS; COMPLEX FORMATIONS; H-RAS ONCOGENE; HETERODIMERIZATION; INTENSIVE RESEARCH; KINASE ACTIVITY; MULTIMERIC; PROTEIN COMPLEXES; TUMOR SUPPRESSOR GENES; TUMOR SUPPRESSORS;

CELL DEATH; CELL PROLIFERATION; SIGNAL TRANSDUCTION;

ENZYMES;

C RAF KINASE; DIRAS3 PROTEIN; H RAS PROTEIN; RAF PROTEIN; RAS PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; DIRAS3 GENE; ENZYME ACTIVITY; GENE ACTIVATION; GENE INTERACTION; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TRANSPORT; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOSKELETON; DIMERIZATION; GENES, TUMOR SUPPRESSOR; HUMANS; MAP KINASE SIGNALING SYSTEM; MULTIPROTEIN COMPLEXES; PRENYLATION; PROTO-ONCOGENE PROTEINS C-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); RHO GTP-BINDING PROTEINS;

EID: 84863334554     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.343780     Document Type: Article

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