B- and C-RAF display essential differences in their binding to Ras: The isotype-specific N terminus of B-RAF facilitates Ras binding

Journal of Biological Chemistry

Volumn 282, Issue 36, 2007, Pages 26503-26516

  Fischer, Andreas ^a   Hekman, Mirko ^a   Kuhlmann, Jürgen ^b   Rubio, Ignacio ^c   Wiese, Stefan ^d,e   Rapp, Ulf R ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSOLIC ENVIRONMENT; MEMBRANE LIPIDS; RAF KINASES;

ACTIVATION ENERGY; BINDING ENERGY; CELL MEMBRANES; CHEMICAL ANALYSIS; LIPIDS;

ENZYMES;

B RAF KINASE; PROTEIN C RAF; PROTEIN H RAS; PROTEIN SERINE THREONINE KINASE; RAS PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION;

ANIMALS; CELL LINE; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOPLASM; HUMANS; ONCOGENE PROTEIN P21(RAS); PC12 CELLS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF; RATS; SPODOPTERA;

EID: 34548819601     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M607458200     Document Type: Article

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