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Volumn 122, Issue 2, 2012, Pages 456-469

Abcg2 deficiency augments oxidative stress and cognitive deficits in Tg-SwDI transgenic mice

Author keywords

Abcg2 deficiency; altered gene expression; Alzheimer's disease; cognitive deficit; oxidative stress; transgenic mice

Indexed keywords

BETA ACTIN; BREAST CANCER RESISTANCE PROTEIN; CYTOKINE; DNA; GLUTATHIONE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LIPID; MONOCYTE CHEMOTACTIC PROTEIN 5; TRANSCRIPTION FACTOR NRF2;

EID: 84863331844     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07783.x     Document Type: Article
Times cited : (22)

References (38)
  • 2
    • 33644778691 scopus 로고    scopus 로고
    • Amyloid-β peptide binds with heme to form a peroxidase: Relationship to the cytopathologies of Alzheimer's disease
    • DOI 10.1073/pnas.0600134103
    • Atamna H., and, Boyle K., (2006) Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease. Proc. Natl Acad. Sci. USA 103, 3381-3386. (Pubitemid 43346478)
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.9 , pp. 3381-3386
    • Atamna, H.1    Boyle, K.2
  • 3
    • 79955064557 scopus 로고    scopus 로고
    • Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease
    • Axelsen P. H., Komatsu H., and, Murray I. V., (2011) Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease. Physiology (Bethesda) 26, 54-69.
    • (2011) Physiology (Bethesda) , vol.26 , pp. 54-69
    • Axelsen, P.H.1    Komatsu, H.2    Murray, I.V.3
  • 4
    • 10844269704 scopus 로고    scopus 로고
    • Role of phenylalanine 20 in Alzheimer's amyloid β-peptide (1-42)-induced oxidative stress and neurotoxicity
    • DOI 10.1021/tx049796w
    • Boyd-Kimball D., Mohmmad Abdul H., Reed T., Sultana R., and, Butterfield D. A., (2004) Role of phenylalanine 20 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity. Chem. Res. Toxicol. 17, 1743-1749. (Pubitemid 39665568)
    • (2004) Chemical Research in Toxicology , vol.17 , Issue.12 , pp. 1743-1749
    • Boyd-Kimball, D.1    Abdul, H.M.2    Reed, T.3    Sultana, R.4    Butterfield, D.A.5
  • 5
    • 15744387176 scopus 로고    scopus 로고
    • Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid β-peptide (1-42) into rat brain: Implications for Alzheimer's disease
    • DOI 10.1016/j.neuroscience.2004.12.022
    • Boyd-Kimball D., Sultana R., Poon H. F., Lynn B. C., Casamenti F., Pepeu G., Klein J. B., and, Butterfield D. A., (2005) Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease. Neuroscience 132, 313-324. (Pubitemid 40417906)
    • (2005) Neuroscience , vol.132 , Issue.2 , pp. 313-324
    • Boyd-Kimball, D.1    Sultana, R.2    Fai Poon, H.3    Lynn, B.C.4    Casamenti, F.5    Pepeu, G.6    Klein, J.B.7    Butterfield, D.A.8
  • 6
    • 77952778858 scopus 로고    scopus 로고
    • Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2
    • Brechbuhl H. M., Gould N., Kachadourian R., Riekhof W. R., Voelker D. R., and, Day B. J,. (2010) Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2. J. Biol. Chem. 285, 16582-16587.
    • (2010) J. Biol. Chem , vol.285 , pp. 16582-16587
    • Brechbuhl, H.M.1    Gould, N.2    Kachadourian, R.3    Riekhof, W.R.4    Voelker, D.R.5    Day, B.J.6
  • 7
    • 16844384057 scopus 로고    scopus 로고
    • The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): Implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients
    • DOI 10.1158/0008-5472.CAN-04-2416
    • Breedveld P., Pluim D., Cipriani G., Wielinga P., van Tellingen O., Schinkel A. H., and, Schellens J. H., (2005) The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients. Cancer Res. 65, 2577-2582. (Pubitemid 40490054)
    • (2005) Cancer Research , vol.65 , Issue.7 , pp. 2577-2582
    • Breedveld, P.1    Pluim, D.2    Cipriani, G.3    Wielinga, P.4    Van Tellingen, O.5    Schinkel, A.H.6    Schellens, J.H.M.7
  • 8
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging
    • Cadenas E., and, Davies K. J., (2000) Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med. 29, 222-230.
    • (2000) Free Radic Biol Med. , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 9
    • 2342644918 scopus 로고    scopus 로고
    • Expression, Up-Regulation, and Transport Activity of the Multidrug-Resistance Protein Abcg2 at the Mouse Blood-Brain Barrier
    • DOI 10.1158/0008-5472.CAN-03-2033
    • Cisternino S., Mercier C., Bourasset F., Roux F., and, Scherrmann J. M., (2004) Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier. Cancer Res. 64, 3296-3301. (Pubitemid 38581436)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3296-3301
    • Cisternino, S.1    Mercier, C.2    Bourasset, F.3    Roux, F.4    Scherrmann, J.-M.5
  • 10
    • 0037113346 scopus 로고    scopus 로고
    • Localisation of breast cancer resistance protein in microvessel endothelium of human brain
    • DOI 10.1097/00001756-200211150-00014
    • Cooray H. C., Blackmore C. G., Maskell L., and, Barrand M. A., (2002) Localisation of breast cancer resistance protein in microvessel endothelium of human brain. NeuroReport 13, 2059-2063. (Pubitemid 36005925)
    • (2002) NeuroReport , vol.13 , Issue.16 , pp. 2059-2063
    • Cooray, H.C.1    Blackmore, C.G.2    Maskell, L.3    Barrand, M.A.4
  • 11
    • 34548215219 scopus 로고    scopus 로고
    • Enhanced cognitive activity-over and above social or physical activity-is required to protect Alzheimer's mice against cognitive impairment, reduce Aβ deposition, and increase synaptic immunoreactivity
    • DOI 10.1016/j.nlm.2007.07.007, PII S1074742707000883
    • Cracchiolo J. R., Mori T., Nazian S. J., Tan J., Potter H., and, Arendash G. W., (2007) Enhanced cognitive activity-over and above social or physical activity-is required to protect Alzheimer's mice against cognitive impairment, reduce Aβ deposition, and increase synaptic immunoreactivity. Neurobiol. Learn. Mem. 88, 277-294. (Pubitemid 47321221)
    • (2007) Neurobiology of Learning and Memory , vol.88 , Issue.3 , pp. 277-294
    • Cracchiolo, J.R.1    Mori, T.2    Nazian, S.J.3    Tan, J.4    Potter, H.5    Arendash, G.W.6
  • 12
    • 2442594971 scopus 로고    scopus 로고
    • Early-onset and Robust Cerebral Microvascular Accumulation of Amyloid β-Protein in Transgenic Mice Expressing Low Levels of a Vasculotropic Dutch/Iowa Mutant Form of Amyloid β-Protein Precursor
    • DOI 10.1074/jbc.M312946200
    • Davis J., Xu F., Deane R., Romanov G., Previti M. L., Zeigler K., Zlokovic B. V., and, Van Nostrand W. E., (2004) Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor. J. Biol. Chem. 279, 20296-20306. (Pubitemid 38623475)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.19 , pp. 20296-20306
    • Davis, J.1    Xu, F.2    Deane, R.3    Romanov, G.4    Previti, M.L.5    Zeigler, K.6    Zlokovic, B.V.7    Van Nostrand, W.E.8
  • 13
    • 33646497484 scopus 로고    scopus 로고
    • Deficient cerebral clearance of vasculotropic mutant Dutch/Iowa Double A beta in human A betaPP transgenic mice
    • Davis J., Xu F., Miao J., Previti M. L., Romanov G., Ziegler K., and, Van Nostrand W. E., (2006) Deficient cerebral clearance of vasculotropic mutant Dutch/Iowa Double A beta in human A betaPP transgenic mice. Neurobiol. Aging 27, 946-954.
    • (2006) Neurobiol. Aging , vol.27 , pp. 946-954
    • Davis, J.1    Xu, F.2    Miao, J.3    Previti, M.L.4    Romanov, G.5    Ziegler, K.6    Van Nostrand, W.E.7
  • 14
    • 34247100991 scopus 로고    scopus 로고
    • Cell proliferation, reactive oxygen and cellular glutathione
    • Day R. M., and, Suzuki Y. J., (2005) Cell proliferation, reactive oxygen and cellular glutathione. Dose Response. 3, 425-442.
    • (2005) Dose Response. , vol.3 , pp. 425-442
    • Day, R.M.1    Suzuki, Y.J.2
  • 15
    • 44149086662 scopus 로고    scopus 로고
    • Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds
    • DOI 10.1124/dmd.107.019257
    • Enokizono J., Kusuhara H., Ose A., Schinkel A. H., and, Sugiyama Y., (2008) Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds. Drug Metab. Dispos. 36, 995-1002. (Pubitemid 351717455)
    • (2008) Drug Metabolism and Disposition , vol.36 , Issue.6 , pp. 995-1002
    • Enokizono, J.1    Kusuhara, H.2    Ose, A.3    Schinkel, A.H.4    Sugiyama, Y.5
  • 16
    • 34447636918 scopus 로고    scopus 로고
    • Phagocytosis of amyloid-β and inflammation: Two faces of innate immunity in Alzheimer's disease
    • Fiala M., Cribbs D. H., Rosenthal M., and, Bernard G., (2007) Phagocytosis of amyloid-beta and inflammation: two faces of innate immunity in Alzheimer's disease. J Alzheimers Dis. 11, 457-463. (Pubitemid 47094016)
    • (2007) Journal of Alzheimer's Disease , vol.11 , Issue.4 , pp. 457-463
    • Fiala, M.1    Cribbs, D.H.2    Rosenthal, M.3    Bernard, G.4
  • 17
    • 34548163922 scopus 로고    scopus 로고
    • Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress
    • DOI 10.1016/j.coph.2007.06.003, PII S1471489207001038, Cancer/Immunomodulation
    • Gallogly M. M., and, Mieyal J. J., (2007) Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress. Curr. Opin. Pharmacol. 7, 381-391. (Pubitemid 47304000)
    • (2007) Current Opinion in Pharmacology , vol.7 , Issue.4 , pp. 381-391
    • Gallogly, M.M.1    Mieyal, J.J.2
  • 19
    • 0035690770 scopus 로고    scopus 로고
    • Inflammatory factors are elevated in brain microvessels in Alzheimer's disease
    • DOI 10.1016/S0197-4580(01)00276-7, PII S0197458001002767
    • Grammas P., and, Ovase R., (2001) Inflammatory factors are elevated in brain microvessels in Alzheimer's disease. Neurobiol. Aging 22, 837-842. (Pubitemid 34066550)
    • (2001) Neurobiology of Aging , vol.22 , Issue.6 , pp. 837-842
    • Grammas, P.1    Ovase, R.2
  • 21
    • 39849110726 scopus 로고    scopus 로고
    • The GSK3 hypothesis of Alzheimer's disease
    • DOI 10.1111/j.1471-4159.2007.05194.x
    • Hooper C., Killick R., and, Lovestone S., (2008) The GSK3 hypothesis of Alzheimer's disease. J. Neurochem. 104, 1433-1439. (Pubitemid 351316776)
    • (2008) Journal of Neurochemistry , vol.104 , Issue.6 , pp. 1433-1439
    • Hooper, C.1    Killick, R.2    Lovestone, S.3
  • 22
    • 3342996554 scopus 로고    scopus 로고
    • Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)
    • DOI 10.1111/j.1471-4159.2004.02537.x
    • Hori S., Ohtsuki S., Tachikawa M., Kimura N., Kondo T., Watanabe M., Nakashima E., and, Terasaki T., (2004) Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s). J. Neurochem. 90, 526-536. (Pubitemid 38989383)
    • (2004) Journal of Neurochemistry , vol.90 , Issue.3 , pp. 526-536
    • Hori, S.1    Ohtsuki, S.2    Tachikawa, M.3    Kimura, N.4    Kondo, T.5    Watanabe, M.6    Nakashima, E.7    Terasaki, T.8
  • 23
    • 0036323445 scopus 로고    scopus 로고
    • Alzheimer disease and cerebrovascular pathology: An update
    • DOI 10.1007/s007020200068
    • Jellinger K. A., (2002) Alzheimer disease and cerebrovascular pathology: an update. J Neural Transm. 109, 813-836. (Pubitemid 34810776)
    • (2002) Journal of Neural Transmission , vol.109 , Issue.5-6 , pp. 813-836
    • Jellinger, K.A.1
  • 24
    • 52449129626 scopus 로고    scopus 로고
    • Differential changes in synaptic proteins in the Alzheimer frontal cortex with marked increase in PSD-95 postsynaptic protein
    • Leuba G., Savio A., Vernay A., Carnal B., Kraftsik R., Tardif E., Riederer I., and, Riederer BM., (2008a) Differential changes in synaptic proteins in the Alzheimer frontal cortex with marked increase in PSD-95 postsynaptic protein. J. Alzheimers Dis. 15, 139-151.
    • (2008) J. Alzheimers Dis. , vol.15 , pp. 139-151
    • Leuba, G.1    Savio, A.2    Vernay, A.3    Carnal, B.4    Kraftsik, R.5    Tardif, E.6    Riederer, I.7    Riederer, B.M.8
  • 25
    • 43649088478 scopus 로고    scopus 로고
    • Postsynaptic density protein PSD-95 expression in Alzheimer's disease and okadaic acid induced neuritic retraction
    • Leuba G., Walzer C., Vernay A., Carnal B., Kraftsik R., Piotton F., Marin P., Bouras C., and, Savioz A., (2008b) Postsynaptic density protein PSD-95 expression in Alzheimer's disease and okadaic acid induced neuritic retraction. Neurobiol. Dis. 30, 408-419.
    • (2008) Neurobiol. Dis. , vol.30 , pp. 408-419
    • Leuba, G.1    Walzer, C.2    Vernay, A.3    Carnal, B.4    Kraftsik, R.5    Piotton, F.6    Marin, P.7    Bouras, C.8    Savioz, A.9
  • 26
    • 34347383021 scopus 로고    scopus 로고
    • Nitric oxide and nitroxidative stress in Alzheimer's disease
    • Free Radicals and Cell Signaling in Alzheimer's
    • Malinski T., (2007) Nitric oxide and nitroxidative stress in Alzheimer's disease. J Alzheimers Dis. 11, 207-218. (Pubitemid 47018067)
    • (2007) Journal of Alzheimer's Disease , vol.11 , Issue.2 , pp. 207-218
    • Malinski, T.1
  • 27
    • 27644480743 scopus 로고    scopus 로고
    • Role of the breast cancer resistance protein (ABCG2) in drug transport
    • DOI 10.1208/aapsj070112, 12
    • Mao Q., and, Unadkat J. D., (2005) Role of the breast cancer resistance protein (ABCG2) in drug transport. AAPS J. 7, E118-E133. (Pubitemid 41554295)
    • (2005) AAPS Journal , vol.7 , Issue.1
    • Mao, Q.1    Unadkat, J.D.2
  • 28
    • 25144486849 scopus 로고    scopus 로고
    • Cerebral microvascular amyloid β protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid β precursor protein
    • Miao J., Xu F., Davis J., Otte-Holler I., Verbeek M. M., and, Van Nostrand W. E., (2005) Cerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein. Am. J. Pathol. 167, 505-515. (Pubitemid 43026105)
    • (2005) American Journal of Pathology , vol.167 , Issue.2 , pp. 505-515
    • Miao, J.1    Xu, F.2    Davis, J.3    Otte-Holler, I.4    Verbeek, M.M.5    Van Nostrand, W.E.6
  • 29
    • 11844284860 scopus 로고    scopus 로고
    • Human cancer resistance protein: Interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine, and transport of cimetidine
    • DOI 10.1124/jpet.104.073916
    • Pavek P., Merino G., Wagenaar E., Bolscher E., Novotna M., Jonker J. W., and, Schinkel A. H., (2005) Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo(4,5-b)pyridine, and transport of cimetidine. J. Pharmacol. Exp. Ther. 312, 144-152. (Pubitemid 40096463)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.312 , Issue.1 , pp. 144-152
    • Pavek, P.1    Merino, G.2    Wagenaar, E.3    Bolscher, E.4    Novotna, M.5    Jonker, J.W.6    Schinkel, A.H.7
  • 30
    • 44249116000 scopus 로고    scopus 로고
    • Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice
    • Rezai-Zadeh K., Arendash G. W., Hou H., Fernandez F., Jensen M., Runfeldt M., Shytle R. D., and, Tan J., (2008) Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice. Brain Res. 1214, 177-187.
    • (2008) Brain Res. , vol.1214 , pp. 177-187
    • Rezai-Zadeh, K.1    Arendash, G.W.2    Hou, H.3    Fernandez, F.4    Jensen, M.5    Runfeldt, M.6    Shytle, R.D.7    Tan, J.8
  • 31
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
    • DOI 10.1016/S0169-409X(02)00169-2, PII S0169409X02001692
    • Schinkel A. H., and, Jonker J. W., (2003) Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv. Drug Deliv. Rev. 55, 3-29. (Pubitemid 36078452)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.1 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 32
    • 77953141219 scopus 로고    scopus 로고
    • ABC transporters and drug efflux at the blood-brain barrier
    • Shen S., and, Zhang W., (2010) ABC transporters and drug efflux at the blood-brain barrier. Rev. Neurosci. 21, 29-53.
    • (2010) Rev. Neurosci. , vol.21 , pp. 29-53
    • Shen, S.1    Zhang, W.2
  • 33
    • 77956313661 scopus 로고    scopus 로고
    • ABCG2 reduces ROS-mediated toxicity and inflammation: A potential role in Alzheimer's disease
    • Shen S., Callaghan D., Juzwik C., Xiong H., Huang P., and, Zhang W., (2010) ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer's disease. J. Neurochem. 114, 1590-1604.
    • (2010) J. Neurochem. , vol.114 , pp. 1590-1604
    • Shen, S.1    Callaghan, D.2    Juzwik, C.3    Xiong, H.4    Huang, P.5    Zhang, W.6
  • 35
    • 65649142529 scopus 로고    scopus 로고
    • ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides
    • Xiong H., Callaghan D., Jones A., et al. (2009) ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides. J. Neurosci. 29, 5463-5475.
    • (2009) J. Neurosci. , vol.29 , pp. 5463-5475
    • Xiong, H.1    Callaghan, D.2    Jones, A.3
  • 36
    • 80755125653 scopus 로고    scopus 로고
    • Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer's disease
    • Xiong H., Callaghan D., Wodzinska J., Xu J., Premyslova M., Liu Q. Y., Connelly J., and, Zhang W., (2011) Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer's disease. Neurosci Bull. 27, 221-232.
    • (2011) Neurosci Bull. , vol.27 , pp. 221-232
    • Xiong, H.1    Callaghan, D.2    Wodzinska, J.3    Xu, J.4    Premyslova, M.5    Liu, Q.Y.6    Connelly, J.7    Zhang, W.8
  • 38
    • 0642303659 scopus 로고    scopus 로고
    • The expression and functional characterization of ABCG2 in brain endothelial cells and vessels
    • Zhang W., Mojsilovic-Petrovic J., Andrade M. F., Zhang H., Ball M., and, Stanimirovic D. B., (2003) The expression and functional characterization of ABCG2 in brain endothelial cells and vessels. FASEB J. 17, 2085-2087.
    • (2003) FASEB J. , vol.17 , pp. 2085-2087
    • Zhang, W.1    Mojsilovic-Petrovic, J.2    Andrade, M.F.3    Zhang, H.4    Ball, M.5    Stanimirovic, D.B.6


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