Molecular determinants of gem protein inhibition of P/Q-type Ca 2+ channels

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 22749-22758

  Fan, Mingming ^a   Zhang, Wei K ^a   Buraei, Zafir ^a   Yang, Jian ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; DIRECT INTERACTIONS; GTP-BINDING PROTEINS; HIGH VOLTAGE-ACTIVATED; INHIBITORY SITES; MOLECULAR DETERMINANTS; MOLECULAR MECHANISM; PHOSPHATIDYLINOSITOL; PROTEIN EXPRESSION LEVELS; PROTEIN INHIBITION; RGK PROTEINS; XENOPUS OOCYTE;

AMINO ACIDS; CALMODULIN; CELL MEMBRANES;

CALCIUM;

CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALMODULIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL; PROTEIN 14 3 3; PROTEIN GEM; UNCLASSIFIED DRUG;

ADULT ANIMAL; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL STRAIN HEK293; CONTROLLED STUDY; ESCHERICHIA COLI; INHIBITION KINETICS; MOLECULAR CLONING; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN SYNTHESIS; WESTERN BLOTTING; XENOPUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CALCIUM CHANNELS, N-TYPE; CALMODULIN; CELL MEMBRANE; ESCHERICHIA COLI; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDE MAPPING; PROTEIN STRUCTURE, TERTIARY; RABBITS; RATS; SIGNAL TRANSDUCTION; XENOPUS LAEVIS;

EID: 84863327988     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.291872     Document Type: Article

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