Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavβ interaction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 33, 2010, Pages 14887-14892

  Fan, Mingming ^a   Buraei, Zafir ^a   Luo, Huai Rong ^a,b   Levenson Palmer, Rose ^a   Yang, Jian ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

subunit; Electrophysiology; Modulation; Rem, Rem2, Rad, and Gem Kir proteins; T type Ca2+ channels

Indexed keywords

CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CHIMERIC PROTEIN; GEM PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SUBUNIT;

ALPHA CHAIN; ARTICLE; CELL MEMBRANE; CHIMERA; CYTOPLASM; IMMUNOPRECIPITATION; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CELL MEMBRANE POTENTIAL; DRUG EFFECT; FEMALE; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; OOCYTE; PHYSIOLOGY; SEQUENCE HOMOLOGY; WESTERN BLOTTING; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CALCIUM CHANNELS, P-TYPE; CALCIUM CHANNELS, Q-TYPE; CELL LINE; CELL MEMBRANE; FEMALE; HUMANS; IMMUNOPRECIPITATION; KINETICS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; OOCYTES; PROTEIN BINDING; PROTEIN SUBUNITS; SEQUENCE HOMOLOGY, AMINO ACID; XENOPUS LAEVIS;

EID: 77957078802     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1007543107     Document Type: Article

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