Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats

Journal of Neuroimmune Pharmacology

Volumn 7, Issue 2, 2012, Pages 444-453

  Chen, Shiou Lan ^a   Tao, Pao Luh ^b   Chu, Chun Hsien ^a,d   Chen, Shih Heng ^d   Wu, Hsiang En ^c   Tseng, Leon F ^c   Hong, Jau Shyong ^d   Lu, Ru Band ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Addiction; BDNF; Cytokine; Memantine; Morphine

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MEMANTINE; MESSENGER RNA; MORPHINE; ANTIINFLAMMATORY AGENT; NARCOTIC ANALGESIC AGENT; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONDITIONING; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG SEEKING BEHAVIOR; HYPOTHESIS; LOW DRUG DOSE; MALE; MEDIAL PREFRONTAL CORTEX; MORPHINE ADDICTION; NERVOUS SYSTEM INFLAMMATION; NEUROTROPISM; NONHUMAN; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; ANIMAL; BRAIN; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANALGESICS, OPIOID; ANIMALS; ANTI-INFLAMMATORY AGENTS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; DRUG-SEEKING BEHAVIOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MEMANTINE; MORPHINE; MORPHINE DEPENDENCE; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84863327882     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-011-9337-9     Document Type: Article

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