Variants in CYP17 and CYP19 cytochrome P450 genes are associated with onset of Alzheimer's disease in women with Down syndrome

Journal of Alzheimer's Disease

Volumn 28, Issue 3, 2012, Pages 601-612

  Chace, Constance ^a   Pang, Deborah ^a   Weng, Catherine ^a   Temkin, Alexis ^a   Lax, Simon ^a   Silverman, Wayne ^d   Zigman, Warren ^c   Ferin, Michel ^a   Lee, Joseph H ^a,b   Tycko, Benjamin ^a   Schupf, Nicole ^a,c  

^a NewYork Presbyterian Hospital   (United States)

^b Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; aromatase; CYP17; CYP19; Down syndrome; estrogen; genetics

Indexed keywords

AROMATASE; CYTOCHROME P450 17; ESTROGEN; SEX HORMONE BINDING GLOBULIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; COGNITIVE DEFECT; CORRELATION ANALYSIS; DOWN SYNDROME; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HEALTH STATUS; HUMAN; MAJOR CLINICAL STUDY; POSTMENOPAUSE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84863293998     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-110860     Document Type: Article

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