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Volumn 28, Issue 11, 2007, Pages 1670-1681

Estrogen receptor α and its splice variants in the hippocampus in aging and Alzheimer's disease

Author keywords

Aging; Alzheimer's disease; Aromatase; Estrogen receptor ; Hippocampus; Neuronal metabolic activity; Splice variants

Indexed keywords

AROMATASE; ESTROGEN RECEPTOR ALPHA; NUCLEOTIDE; PARAFFIN;

EID: 34548536149     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2006.07.024     Document Type: Article
Times cited : (104)

References (58)
  • 1
    • 0344412913 scopus 로고    scopus 로고
    • Estrogen and the aging hippocampal synapse
    • Adams M.M., and Morrison J.H. Estrogen and the aging hippocampal synapse. Cereb Cortex 13 (2003) 1271-1275
    • (2003) Cereb Cortex , vol.13 , pp. 1271-1275
    • Adams, M.M.1    Morrison, J.H.2
  • 3
    • 0034465071 scopus 로고    scopus 로고
    • An estrogen receptor-α splicing variant mediates both positive and negative effects on gene transcription
    • Bollig A., and Miksicek R.J. An estrogen receptor-α splicing variant mediates both positive and negative effects on gene transcription. Mol Endocrinol 14 (2000) 634-649
    • (2000) Mol Endocrinol , vol.14 , pp. 634-649
    • Bollig, A.1    Miksicek, R.J.2
  • 4
    • 22044455415 scopus 로고    scopus 로고
    • Direct, complex effects of estrogens on basal forebrain cholinergic neurons
    • Bora S.H., Liu Z., Kecojevic A., Merchenthaler I., and Koliatsos V.E. Direct, complex effects of estrogens on basal forebrain cholinergic neurons. Exp Neurol 194 (2005) 506-522
    • (2005) Exp Neurol , vol.194 , pp. 506-522
    • Bora, S.H.1    Liu, Z.2    Kecojevic, A.3    Merchenthaler, I.4    Koliatsos, V.E.5
  • 5
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H., and Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82 (1991) 239-259
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 6
    • 25144511407 scopus 로고    scopus 로고
    • Investigative models for determining hormone therapy-induced outcomes in brain: evidence in support of a healthy cell bias of estrogen action
    • Brinton R.D. Investigative models for determining hormone therapy-induced outcomes in brain: evidence in support of a healthy cell bias of estrogen action. Ann N Y Acad Sci 1052 (2005) 57-74
    • (2005) Ann N Y Acad Sci , vol.1052 , pp. 57-74
    • Brinton, R.D.1
  • 7
    • 0242636873 scopus 로고    scopus 로고
    • Estradiol increases pre- and post-synaptic proteins in the CA1 region of the hippocampus in female rhesus macaques (Macaca mulatta)
    • Choi J.M., Romeo R.D., Brake W.G., Bethea C.L., Rosenwaks Z., and McEwen B.S. Estradiol increases pre- and post-synaptic proteins in the CA1 region of the hippocampus in female rhesus macaques (Macaca mulatta). Endocrinology 144 (2003) 4734-4738
    • (2003) Endocrinology , vol.144 , pp. 4734-4738
    • Choi, J.M.1    Romeo, R.D.2    Brake, W.G.3    Bethea, C.L.4    Rosenwaks, Z.5    McEwen, B.S.6
  • 8
    • 24344507301 scopus 로고    scopus 로고
    • Beta estrogen receptor knockout (BERKO) mice present attenuated hippocampal CA1 long-term potentiation and related memory deficits in contextual fear conditioning
    • Day M., Sung A., Logue S., Bowlby M., and Arias R. Beta estrogen receptor knockout (BERKO) mice present attenuated hippocampal CA1 long-term potentiation and related memory deficits in contextual fear conditioning. Behav Brain Res 164 (2005) 128-131
    • (2005) Behav Brain Res , vol.164 , pp. 128-131
    • Day, M.1    Sung, A.2    Logue, S.3    Bowlby, M.4    Arias, R.5
  • 9
    • 0041883787 scopus 로고    scopus 로고
    • Preliminary evidence that estrogen protects against age-related hippocampal atrophy
    • Eberling J.L., Wu C., Haan M.N., Mungas D., Buonocore M., and Jagust W.J. Preliminary evidence that estrogen protects against age-related hippocampal atrophy. Neurobiol Aging 24 (2003) 725-732
    • (2003) Neurobiol Aging , vol.24 , pp. 725-732
    • Eberling, J.L.1    Wu, C.2    Haan, M.N.3    Mungas, D.4    Buonocore, M.5    Jagust, W.J.6
  • 10
    • 5344232095 scopus 로고    scopus 로고
    • Hippocampus: cognitive processes and neural representations that underlie declarative memory
    • Eichenbaum H. Hippocampus: cognitive processes and neural representations that underlie declarative memory. Neuron 44 (2004) 109-120
    • (2004) Neuron , vol.44 , pp. 109-120
    • Eichenbaum, H.1
  • 11
    • 19544362405 scopus 로고    scopus 로고
    • Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells
    • Emsley J.G., Mitchell B.D., Kempermann G., and Macklis J.D. Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells. Prog Neurobiol 75 (2005) 321-341
    • (2005) Prog Neurobiol , vol.75 , pp. 321-341
    • Emsley, J.G.1    Mitchell, B.D.2    Kempermann, G.3    Macklis, J.D.4
  • 12
    • 33644975004 scopus 로고    scopus 로고
    • RNA integrity and the effect on the real-time qRT-PCR performance
    • Fleige S., and Pfaffl M.W. RNA integrity and the effect on the real-time qRT-PCR performance. Mol Asp Med 27 (2006) 126-139
    • (2006) Mol Asp Med , vol.27 , pp. 126-139
    • Fleige, S.1    Pfaffl, M.W.2
  • 13
    • 0025281641 scopus 로고
    • Hippocampal plasticity in normal aging and decreased plasticity in Alzheimer's disease
    • Flood D.G., and Coleman P.D. Hippocampal plasticity in normal aging and decreased plasticity in Alzheimer's disease. Prog Brain Res 83 (1990) 435-443
    • (1990) Prog Brain Res , vol.83 , pp. 435-443
    • Flood, D.G.1    Coleman, P.D.2
  • 14
    • 0141483708 scopus 로고    scopus 로고
    • Glutamatergic systems in Alzheimer's disease
    • Francis P.T. Glutamatergic systems in Alzheimer's disease. Int J Geriatr Psychiatry 18 (2003) S15-S21
    • (2003) Int J Geriatr Psychiatry , vol.18
    • Francis, P.T.1
  • 15
    • 0035979810 scopus 로고    scopus 로고
    • Examination of estradiol effects on the rapid estradiol mediated increase in hippocampal synaptic transmission in estrogen receptor alpha knockout mice
    • Fugger H.N., Kumar A., Lubahn D.B., Korach K.S., and Foster T.C. Examination of estradiol effects on the rapid estradiol mediated increase in hippocampal synaptic transmission in estrogen receptor alpha knockout mice. Neurosci Lett 309 (2001) 207-209
    • (2001) Neurosci Lett , vol.309 , pp. 207-209
    • Fugger, H.N.1    Kumar, A.2    Lubahn, D.B.3    Korach, K.S.4    Foster, T.C.5
  • 16
    • 0038675231 scopus 로고    scopus 로고
    • The naturally occurring variant of estrogen receptor (ER) ERΔe7 suppresses estrogen-dependent transcriptional activation by both wild-type ERα and ERβ
    • Garcia Pedrero J.M., Zuazua P., Martinez-Campa C., Lazo P.S., and Ramos S. The naturally occurring variant of estrogen receptor (ER) ERΔe7 suppresses estrogen-dependent transcriptional activation by both wild-type ERα and ERβ. Endocrinology 144 (2003) 2967-2976
    • (2003) Endocrinology , vol.144 , pp. 2967-2976
    • Garcia Pedrero, J.M.1    Zuazua, P.2    Martinez-Campa, C.3    Lazo, P.S.4    Ramos, S.5
  • 18
    • 0035851253 scopus 로고    scopus 로고
    • Quantitative analysis of ER alpha and GAD colocalization in the hippocampus of the adult female rat
    • Hart S.A., Patton J.D., and Woolley C.S. Quantitative analysis of ER alpha and GAD colocalization in the hippocampus of the adult female rat. J Comp Neurol 440 (2001) 144-155
    • (2001) J Comp Neurol , vol.440 , pp. 144-155
    • Hart, S.A.1    Patton, J.D.2    Woolley, C.S.3
  • 19
    • 0033377484 scopus 로고    scopus 로고
    • A unifying hypothesis of Alzheimer's disease. II. Pathophysiological processes
    • Heininger K. A unifying hypothesis of Alzheimer's disease. II. Pathophysiological processes. Hum Psychopharmacol Clin Exp 14 (1999) 525-581
    • (1999) Hum Psychopharmacol Clin Exp , vol.14 , pp. 525-581
    • Heininger, K.1
  • 20
    • 29444434719 scopus 로고    scopus 로고
    • Menopause and disorders of the central nervous system
    • Henderson V.W. Menopause and disorders of the central nervous system. Minerva Ginecol 57 (2005) 579-592
    • (2005) Minerva Ginecol , vol.57 , pp. 579-592
    • Henderson, V.W.1
  • 21
    • 18844413533 scopus 로고    scopus 로고
    • Estrogen induces a rapid increase in galanin levels in female rat hippocampal formation-possibly a nongenomic/indirect effect
    • Hilke S., Theodorsson A., Fetissov S., Aman K., Holm L., Hokfelt T., et al. Estrogen induces a rapid increase in galanin levels in female rat hippocampal formation-possibly a nongenomic/indirect effect. Eur J Neurosci 21 (2005) 2089-2099
    • (2005) Eur J Neurosci , vol.21 , pp. 2089-2099
    • Hilke, S.1    Theodorsson, A.2    Fetissov, S.3    Aman, K.4    Holm, L.5    Hokfelt, T.6
  • 22
    • 0028225088 scopus 로고
    • Novel exon 1 of the aromatase gene specific for aromatase transcripts in human brain
    • Honda S., Harada N., and Takagi Y. Novel exon 1 of the aromatase gene specific for aromatase transcripts in human brain. Biochem Biophys Res Commun 198 (1994) 1153-1160
    • (1994) Biochem Biophys Res Commun , vol.198 , pp. 1153-1160
    • Honda, S.1    Harada, N.2    Takagi, Y.3
  • 23
    • 0042473074 scopus 로고    scopus 로고
    • Decreased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients
    • Hu X.Y., Qin S., Lu Y.P., Ravid R., Swaab D.F., and Zhou J.N. Decreased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients. Acta Neuropathol 106 (2003) 213-220
    • (2003) Acta Neuropathol , vol.106 , pp. 213-220
    • Hu, X.Y.1    Qin, S.2    Lu, Y.P.3    Ravid, R.4    Swaab, D.F.5    Zhou, J.N.6
  • 24
    • 21244433611 scopus 로고    scopus 로고
    • Estrogen receptor-alpha splice variants in the medial mamillary nucleus of Alzheimer's disease patients: identification of a novel MB1 isoform
    • Ishunina T.A., Swaab D.F., and Fischer D.F. Estrogen receptor-alpha splice variants in the medial mamillary nucleus of Alzheimer's disease patients: identification of a novel MB1 isoform. J Clin Endocrinol Metab 90 (2005) 3757-3765
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3757-3765
    • Ishunina, T.A.1    Swaab, D.F.2    Fischer, D.F.3
  • 25
    • 0042237040 scopus 로고    scopus 로고
    • Increased neuronal metabolic activity and estrogen receptors in the vertical limb of the diagonal band of Broca in Alzheimer's disease: relation to sex and aging
    • Ishunina T.A., and Swaab D.F. Increased neuronal metabolic activity and estrogen receptors in the vertical limb of the diagonal band of Broca in Alzheimer's disease: relation to sex and aging. Exp Neurol 183 (2003) 159-172
    • (2003) Exp Neurol , vol.183 , pp. 159-172
    • Ishunina, T.A.1    Swaab, D.F.2
  • 26
    • 10044226276 scopus 로고    scopus 로고
    • Diminished aromatase immunoreactivity in the hypothalamus, but not the in basal forebrain nuclei in Alzheimer's disease
    • Ishunina T.A., van Beurden D., van der Meulen G., Unmehopa U.A., Hol E.M., Huitinga I., et al. Diminished aromatase immunoreactivity in the hypothalamus, but not the in basal forebrain nuclei in Alzheimer's disease. Neurobiol Aging 26 (2005) 173-194
    • (2005) Neurobiol Aging , vol.26 , pp. 173-194
    • Ishunina, T.A.1    van Beurden, D.2    van der Meulen, G.3    Unmehopa, U.A.4    Hol, E.M.5    Huitinga, I.6
  • 27
    • 0037643398 scopus 로고    scopus 로고
    • Rapid effects of estrogen on G protein-coupled receptor activation of potassium channels in the central nervous system (CNS)
    • Kelly M.J., Qiu J., Wagner E.J., and Ronnekleiv O.K. Rapid effects of estrogen on G protein-coupled receptor activation of potassium channels in the central nervous system (CNS). J Steroid Biochem Mol Biol 83 (2002) 187-193
    • (2002) J Steroid Biochem Mol Biol , vol.83 , pp. 187-193
    • Kelly, M.J.1    Qiu, J.2    Wagner, E.J.3    Ronnekleiv, O.K.4
  • 28
    • 0028314538 scopus 로고
    • Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue
    • Koehorst S.G., Cox J.J., Donker G.H., Lopes da Silva S., Burbach J.P., Thijssen J.H., et al. Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue. Mol Cell Endocrinol 101 (1994) 237-245
    • (1994) Mol Cell Endocrinol , vol.101 , pp. 237-245
    • Koehorst, S.G.1    Cox, J.J.2    Donker, G.H.3    Lopes da Silva, S.4    Burbach, J.P.5    Thijssen, J.H.6
  • 29
    • 0022773520 scopus 로고
    • Localization of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor
    • Kumar V., Green S., Staub A., and Chambon P. Localization of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J 5 (1986) 2231-2236
    • (1986) EMBO J , vol.5 , pp. 2231-2236
    • Kumar, V.1    Green, S.2    Staub, A.3    Chambon, P.4
  • 30
    • 0035184372 scopus 로고    scopus 로고
    • Brain region-specific up-regulation of mouse apolipoprotein E by pharmacological estrogen treatments
    • Levin-Allerhand J., McEwen B.S., Lominska C.E., Lubahn D.B., Korach K.S., and Smith J.D. Brain region-specific up-regulation of mouse apolipoprotein E by pharmacological estrogen treatments. J Neurochem 79 (2001) 796-803
    • (2001) J Neurochem , vol.79 , pp. 796-803
    • Levin-Allerhand, J.1    McEwen, B.S.2    Lominska, C.E.3    Lubahn, D.B.4    Korach, K.S.5    Smith, J.D.6
  • 31
    • 0034603609 scopus 로고    scopus 로고
    • Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition
    • Maki P.M., and Resnick S.M. Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition. Neurobiol Aging 21 (2000) 373-383
    • (2000) Neurobiol Aging , vol.21 , pp. 373-383
    • Maki, P.M.1    Resnick, S.M.2
  • 32
    • 25144446222 scopus 로고    scopus 로고
    • A systematic review of clinical trials of hormone therapy on cognitive function: effects of age at initiation and progestin use
    • Maki P.M. A systematic review of clinical trials of hormone therapy on cognitive function: effects of age at initiation and progestin use. Ann N Y Acad Sci 1052 (2005) 182-197
    • (2005) Ann N Y Acad Sci , vol.1052 , pp. 182-197
    • Maki, P.M.1
  • 33
    • 0036453495 scopus 로고    scopus 로고
    • Ovarian hormone replacement to aged ovariectomized female rats benefits acquisition of the morris water maze
    • Markham J.A., Pych J.C., and Juraska J.M. Ovarian hormone replacement to aged ovariectomized female rats benefits acquisition of the morris water maze. Horm Behav 42 (2002) 284-293
    • (2002) Horm Behav , vol.42 , pp. 284-293
    • Markham, J.A.1    Pych, J.C.2    Juraska, J.M.3
  • 34
    • 11144224509 scopus 로고    scopus 로고
    • The 17alpha and 17beta isomers of estradiol both induce rapid spine synapse formation in the CA1 hippocampal subfield of ovariectomized female rats
    • McLusky N.J., Luine V.N., Hajszan T., and Leranth C. The 17alpha and 17beta isomers of estradiol both induce rapid spine synapse formation in the CA1 hippocampal subfield of ovariectomized female rats. Endocrinology 146 (2005) 287-293
    • (2005) Endocrinology , vol.146 , pp. 287-293
    • McLusky, N.J.1    Luine, V.N.2    Hajszan, T.3    Leranth, C.4
  • 35
    • 1842474964 scopus 로고    scopus 로고
    • Evaluating RNA status for RT-PCR in extracts of postmortem human brain tissue
    • Miller C.L., Diglisic S., Leister F., Webster M., and Yolken R.H. Evaluating RNA status for RT-PCR in extracts of postmortem human brain tissue. BioTechniques 36 (2004) 628-633
    • (2004) BioTechniques , vol.36 , pp. 628-633
    • Miller, C.L.1    Diglisic, S.2    Leister, F.3    Webster, M.4    Yolken, R.H.5
  • 36
    • 4544375040 scopus 로고    scopus 로고
    • The contribution of the study of neurodegenerative disorders to the understanding of human memory
    • Panegyres P.K. The contribution of the study of neurodegenerative disorders to the understanding of human memory. Q J Med 97 (2004) 555-567
    • (2004) Q J Med , vol.97 , pp. 555-567
    • Panegyres, P.K.1
  • 37
    • 0030472694 scopus 로고    scopus 로고
    • Identification of a variant estrogen receptor lacking exon 4 and its coexpression with wild type estrogen receptor in ovarian carcinomas
    • Park W., Choi J.J., Hwang E.S., and Lee J.H. Identification of a variant estrogen receptor lacking exon 4 and its coexpression with wild type estrogen receptor in ovarian carcinomas. Clin Cancer Res 2 (1996) 2029-2035
    • (1996) Clin Cancer Res , vol.2 , pp. 2029-2035
    • Park, W.1    Choi, J.J.2    Hwang, E.S.3    Lee, J.H.4
  • 38
    • 0034986161 scopus 로고    scopus 로고
    • Differential subcellular distribution and transcriptional activity of sigmaE3, sigmaE4, and sigmaE3-4 isoforms of the rat estrogen receptor-alpha
    • Pasqualini C., Guivarc'h D., Barnier J.V., Guibert B., Vincent J.D., and Vernier P. Differential subcellular distribution and transcriptional activity of sigmaE3, sigmaE4, and sigmaE3-4 isoforms of the rat estrogen receptor-alpha. Mol Endocrinol 15 (2001) 894-908
    • (2001) Mol Endocrinol , vol.15 , pp. 894-908
    • Pasqualini, C.1    Guivarc'h, D.2    Barnier, J.V.3    Guibert, B.4    Vincent, J.D.5    Vernier, P.6
  • 39
    • 21744463059 scopus 로고    scopus 로고
    • Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex
    • Perlman W.R., Matsumoto M., Beltaifa S., Hyde T.M., Saunders R.C., Webster M.J., et al. Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex. Neuroscience 134 (2005) 81-95
    • (2005) Neuroscience , vol.134 , pp. 81-95
    • Perlman, W.R.1    Matsumoto, M.2    Beltaifa, S.3    Hyde, T.M.4    Saunders, R.C.5    Webster, M.J.6
  • 40
    • 0037275211 scopus 로고    scopus 로고
    • Para/autocrine regulation of estrogen receptors in hippocampal neurons
    • Prange-Kiel J., Wehrenberg U., Jarry H., and Rune G.M. Para/autocrine regulation of estrogen receptors in hippocampal neurons. Hippocampus 13 (2003) 226-234
    • (2003) Hippocampus , vol.13 , pp. 226-234
    • Prange-Kiel, J.1    Wehrenberg, U.2    Jarry, H.3    Rune, G.M.4
  • 41
    • 0033457358 scopus 로고    scopus 로고
    • Multiple receptors for neuropeptide Y in the hippocampus: putative roles in seizures and cognition.
    • Redrobe J.P., Dumont Y., St-Pierre J.A., and Quirion R. Multiple receptors for neuropeptide Y in the hippocampus: putative roles in seizures and cognition. Brain Res 848 (1999) 153-166
    • (1999) Brain Res , vol.848 , pp. 153-166
    • Redrobe, J.P.1    Dumont, Y.2    St-Pierre, J.A.3    Quirion, R.4
  • 43
    • 0035958527 scopus 로고    scopus 로고
    • Hippocampal estrogen beta-receptor immunoreactivity is increased in Alzheimer's disease
    • Savaskan E., Olivieri G., Meier F., Ravid R., and Muller-Spahn F. Hippocampal estrogen beta-receptor immunoreactivity is increased in Alzheimer's disease. Brain Res 908 (2001) 113-119
    • (2001) Brain Res , vol.908 , pp. 113-119
    • Savaskan, E.1    Olivieri, G.2    Meier, F.3    Ravid, R.4    Muller-Spahn, F.5
  • 44
    • 0642306449 scopus 로고    scopus 로고
    • Onset of estrogen replacement has a critical effect on synaptic density of CA1 hippocampus in ovariectomized adult rats
    • Silva I., Mello L.E., Freymuller E., Haidar M.A., and Baracat E.C. Onset of estrogen replacement has a critical effect on synaptic density of CA1 hippocampus in ovariectomized adult rats. Menopause 10 (2003) 406-411
    • (2003) Menopause , vol.10 , pp. 406-411
    • Silva, I.1    Mello, L.E.2    Freymuller, E.3    Haidar, M.A.4    Baracat, E.C.5
  • 46
    • 0033825993 scopus 로고    scopus 로고
    • Effects of age on gene expression during estrogen-induced synaptic sprouting in the female rat
    • Stone D.J., Rozovsky I., Morgan T.E., Anderson C.P., Lopez L.M., Shick J., et al. Effects of age on gene expression during estrogen-induced synaptic sprouting in the female rat. Exp Neurol 165 (2000) 46-57
    • (2000) Exp Neurol , vol.165 , pp. 46-57
    • Stone, D.J.1    Rozovsky, I.2    Morgan, T.E.3    Anderson, C.P.4    Lopez, L.M.5    Shick, J.6
  • 47
    • 3142658612 scopus 로고    scopus 로고
    • Hippocampal function in cognition
    • Sweatt J.D. Hippocampal function in cognition. Psychopharmacology 174 (2004) 99-110
    • (2004) Psychopharmacology , vol.174 , pp. 99-110
    • Sweatt, J.D.1
  • 48
    • 20044380713 scopus 로고    scopus 로고
    • Hippocampus, III: GABA-containing cell bodies and GAD mRNA
    • Tamminga C.A. Hippocampus, III: GABA-containing cell bodies and GAD mRNA. Am J Psychiatry 162 (2005) 450
    • (2005) Am J Psychiatry , vol.162 , pp. 450
    • Tamminga, C.A.1
  • 49
    • 11144328239 scopus 로고    scopus 로고
    • Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose- and time-dependent manner
    • Tanapat P., Hastings N.B., and Gould E. Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose- and time-dependent manner. J Comp Neurol 481 (2005) 252-265
    • (2005) J Comp Neurol , vol.481 , pp. 252-265
    • Tanapat, P.1    Hastings, N.B.2    Gould, E.3
  • 50
    • 0033565292 scopus 로고    scopus 로고
    • Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat
    • Tanapat P., Hastings N.B., Reeves A.J., and Gould E. Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat. J Neurosci 19 (1999) 5792-5801
    • (1999) J Neurosci , vol.19 , pp. 5792-5801
    • Tanapat, P.1    Hastings, N.B.2    Reeves, A.J.3    Gould, E.4
  • 51
    • 0028824323 scopus 로고
    • Effects of age on messenger RNA expression of glucocorticoid, thyroid hormone, androgen, and estrogen receptors in postmortem human hippocampus.
    • Tohgi H., Utsugisawa K., Yamagata M., and Yoshimura M. Effects of age on messenger RNA expression of glucocorticoid, thyroid hormone, androgen, and estrogen receptors in postmortem human hippocampus. Brain Res 700 (1995) 245-253
    • (1995) Brain Res , vol.700 , pp. 245-253
    • Tohgi, H.1    Utsugisawa, K.2    Yamagata, M.3    Yoshimura, M.4
  • 52
    • 0032907868 scopus 로고    scopus 로고
    • Novel mechanisms of estrogen action in the brain: new players in an old story
    • Toran-Allerand C.D., Singh M., and Setalo Jr. G. Novel mechanisms of estrogen action in the brain: new players in an old story. Front Neuroendocrinol 20 (1999) 97-121
    • (1999) Front Neuroendocrinol , vol.20 , pp. 97-121
    • Toran-Allerand, C.D.1    Singh, M.2    Setalo Jr., G.3
  • 53
    • 20844453021 scopus 로고    scopus 로고
    • Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor α N terminus
    • Valley C.C., Metivier R., Solodin N.M., Fowler A.M., Mashek M.T., Hill L., et al. Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor α N terminus. Mol Cell Biol 25 (2005) 5417-5428
    • (2005) Mol Cell Biol , vol.25 , pp. 5417-5428
    • Valley, C.C.1    Metivier, R.2    Solodin, N.M.3    Fowler, A.M.4    Mashek, M.T.5    Hill, L.6
  • 54
    • 0028101798 scopus 로고
    • Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease
    • Vickers J.C., Riederer B.M., Marugg R.A., Buee-Scherrer V., Buee L., Delacourte A., et al. Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease. Neuroscience 62 (1994) 1-13
    • (1994) Neuroscience , vol.62 , pp. 1-13
    • Vickers, J.C.1    Riederer, B.M.2    Marugg, R.A.3    Buee-Scherrer, V.4    Buee, L.5    Delacourte, A.6
  • 55
    • 0032420026 scopus 로고    scopus 로고
    • Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and nonsynaptic interactions
    • Vizi E.S., and Kiss J.P. Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and nonsynaptic interactions. Hippocampus 8 (1998) 566-607
    • (1998) Hippocampus , vol.8 , pp. 566-607
    • Vizi, E.S.1    Kiss, J.P.2
  • 56
    • 0028122463 scopus 로고
    • Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
    • West M.J., Coleman P.D., Flood D.G., and Troncoso J.C. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 344 (1994) 769-772
    • (1994) Lancet , vol.344 , pp. 769-772
    • West, M.J.1    Coleman, P.D.2    Flood, D.G.3    Troncoso, J.C.4
  • 57
    • 0026713869 scopus 로고
    • Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors
    • Ylikomi T., Bocquel M.T., Berry M., Gronemeyer H., and Chambon P. Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors. EMBO J 11 (1992) 3681-3694
    • (1992) EMBO J , vol.11 , pp. 3681-3694
    • Ylikomi, T.1    Bocquel, M.T.2    Berry, M.3    Gronemeyer, H.4    Chambon, P.5
  • 58
    • 1842708948 scopus 로고    scopus 로고
    • Disruption of estrogen receptor beta in mice brain results in pathological alterations resembling Alzheimer disease
    • Zhang Q.H., Huang Y.H., Hu Y.Z., Wei G.Z., Han X.F., Lu S.Y., et al. Disruption of estrogen receptor beta in mice brain results in pathological alterations resembling Alzheimer disease. Acta Pharmacol Sin 25 (2004) 452-457
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 452-457
    • Zhang, Q.H.1    Huang, Y.H.2    Hu, Y.Z.3    Wei, G.Z.4    Han, X.F.5    Lu, S.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.