-
1
-
-
60849114965
-
Distinctive localization of antigen-presenting cells in human lymph nodes
-
Angel CE, Chen CJJ, Horlacher OC, Winkler S, John T, Browning J, MacGregor D, Cebon J, Dunbar PR (2009) Distinctive localization of antigen-presenting cells in human lymph nodes. Blood 113(6): 1257-1267
-
(2009)
Blood
, vol.113
, Issue.6
, pp. 1257-1267
-
-
Angel, C.E.1
Chen, C.J.J.2
Horlacher, O.C.3
Winkler, S.4
John, T.5
Browning, J.6
MacGregor, D.7
Cebon, J.8
Dunbar, P.R.9
-
2
-
-
33646467930
-
Cutting edge: CD1a+ antigen-presenting cells in human dermis respond rapidly to CCR7 ligands
-
Angel CE, George E, Brooks AES, Ostrovsky LL, Brown TLH, Dunbar PR (2006) Cutting edge: CD1a+ antigen-presenting cells in human dermis respond rapidly to CCR7 ligands. J Immunol 176(10): 5730-5734
-
(2006)
J Immunol
, vol.176
, Issue.10
, pp. 5730-5734
-
-
Angel, C.E.1
George, E.2
Brooks, A.E.S.3
Ostrovsky, L.L.4
Brown, T.L.H.5
Dunbar, P.R.6
-
3
-
-
0026011266
-
Anti-tumour activity of flavone acetic acid (NSC 347512) in mice-influence of immune status
-
Bibby MC, Phillips RM, Double JA, Pratesi G (1991) Anti-tumour activity of flavone acetic acid (NSC 347512) in mice-influence of immune status. Br J Cancer 63(1): 57-62
-
(1991)
Br J Cancer
, vol.63
, Issue.1
, pp. 57-62
-
-
Bibby, M.C.1
Phillips, R.M.2
Double, J.A.3
Pratesi, G.4
-
4
-
-
77956806026
-
Labeling of oxidizable proteins with a photoactivatable analog of the antitumor agent DMXAA: Evidence for redox signaling in its mode of action
-
Brauer R, Wang LCS, Woon ST, Bridewell DJA, Henare K, Malinger D, Palmer BD, Vogel SN, Kieda C, Tijono SM, Ching LM (2010) Labeling of oxidizable proteins with a photoactivatable analog of the antitumor agent DMXAA: evidence for redox signaling in its mode of action. Neoplasia 12(9): 755-765
-
(2010)
Neoplasia
, vol.12
, Issue.9
, pp. 755-765
-
-
Brauer, R.1
Wang, L.C.S.2
Woon, S.T.3
Bridewell, D.J.A.4
Henare, K.5
Malinger, D.6
Palmer, B.D.7
Vogel, S.N.8
Kieda, C.9
Tijono, S.M.10
Ching, L.M.11
-
5
-
-
63849132087
-
Genetics, cellular biology and tumor microenvironment of melanoma
-
Ch'ng S, Tan S (2009) Genetics, cellular biology and tumor microenvironment of melanoma. Front Biosci 14: 918-928
-
(2009)
Front Biosci
, vol.14
, pp. 918-928
-
-
Ch'Ng, S.1
Tan, S.2
-
6
-
-
0037125028
-
Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
-
Ching L-M, Cao Z, Kieda C, Zwain S, Jameson MB, Baguley BC (2002) Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Br J Cancer 86: 1937-1942
-
(2002)
Br J Cancer
, vol.86
, pp. 1937-1942
-
-
Ching, L.-M.1
Cao, Z.2
Kieda, C.3
Zwain, S.4
Jameson, M.B.5
Baguley, B.C.6
-
7
-
-
0033565644
-
Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice
-
Ching L-M, Goldsmith D, Joseph WR, Korner H, Sedgwick JD, Baguley BC (1999a) Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice. Cancer Res 59: 3304-3307 (Pubitemid 29334480)
-
(1999)
Cancer Research
, vol.59
, Issue.14
, pp. 3304-3307
-
-
Ching, L.-M.1
Goldsmith, D.2
Joseph, W.R.3
Korner, H.4
Sedgwick, J.D.5
Baguley, B.C.6
-
8
-
-
0033201439
-
Induction of STAT and NFκB activation by the antitumor agents 5,6-dimethylxanthenone-4-acetic acid and flavone acetic acid in a murine macrophage cell line
-
DOI 10.1016/S0006-2952(99)00194-X, PII S000629529900194X
-
Ching L-M, Young HA, Eberly K, Yu C-R (1999b) Induction of STAT and NFkB activation by the antitumor agents 5,6-dimethylxanthenone-4-acetic acid and flavone acetic acid in a murine macrophage cell line. Biochem Pharmacol 58: 1173-1181 (Pubitemid 29381518)
-
(1999)
Biochemical Pharmacology
, vol.58
, Issue.7
, pp. 1173-1181
-
-
Ching, L.-M.1
Young, H.A.2
Eberly, K.3
Yu, C.-R.4
-
9
-
-
1642352048
-
Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice
-
DOI 10.1038/sj.bjc.6601606
-
Ching L-M, Zwain S, Baguley BC (2004) Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice. Br J Cancer 90(4): 906-910 (Pubitemid 38406605)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.4
, pp. 906-910
-
-
Ching, L.-M.1
Zwain, S.2
Baguley, B.C.3
-
10
-
-
0026686247
-
Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone- 4-acetic acid in immune deficient mice
-
Ching LM, Joseph WR, Baguley BC (1992) Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice. Br J Cancer 66: 128-130
-
(1992)
Br J Cancer
, vol.66
, pp. 128-130
-
-
Ching, L.M.1
Joseph, W.R.2
Baguley, B.C.3
-
11
-
-
84863295091
-
Labeling of oxidizable proteins with a photoactivatable analog of the antitumor agent DMXAA: Evidence for redox signaling in its mode of action [abstract]
-
17-21 April 2010. AACR: Washington, DC; Philadelphia, PA, (abstract 24)
-
Ching LM, Wang LC, Brauer R, Bridewell DJA, Henare K, Palmer BD (2010) Labeling of oxidizable proteins with a photoactivatable analog of the antitumor agent DMXAA: evidence for redox signaling in its mode of action [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 17-21 April 2010. AACR: Washington, DC; Philadelphia, PA, (abstract 24)
-
(2010)
Proceedings of the 101st Annual Meeting of the American Association for Cancer Research
-
-
Ching, L.M.1
Wang, L.C.2
Brauer, R.3
Bridewell, D.J.A.4
Henare, K.5
Palmer, B.D.6
-
12
-
-
0038825777
-
Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice
-
Creighton C, Kuick R, Misek D, Rickman D, Brichory F, Rouillard J-M, Omenn G, Hanash S (2003) Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice. Genome Biol 4(7): R46
-
(2003)
Genome Biol
, vol.4
, Issue.7
-
-
Creighton, C.1
Kuick, R.2
Misek, D.3
Rickman, D.4
Brichory, F.5
Rouillard, J.-M.6
Omenn, G.7
Hanash, S.8
-
13
-
-
20244373775
-
Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation
-
DOI 10.1158/1541-7786.MCR-04-0189
-
Creighton CJ, Bromberg-White JL, Misek DE, Monsma DJ, Brichory F, Kuick R, Giordano TJ, Gao W, Omenn GS, Webb CP, Hanash SM (2005) Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation. Mol Cancer Res 3(3): 119-129 (Pubitemid 40524895)
-
(2005)
Molecular Cancer Research
, vol.3
, Issue.3
, pp. 119-129
-
-
Creighton, C.J.1
Bromberg-White, J.L.2
Misek, D.E.3
Monsma, D.J.4
Brichory, F.5
Kuick, R.6
Giordano, T.J.7
Gao, W.8
Omenn, G.S.9
Webb, C.P.10
Hanash, S.M.11
-
14
-
-
69249222379
-
Polarization of tumor-associated neutrophil phenotype by TGF-[beta]: 'N1' vs 'N2' TAN
-
Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, Worthen GS, Albelda SM (2009) Polarization of tumor-associated neutrophil phenotype by TGF-[beta]: 'N1' vs 'N2' TAN. Cancer Cell 16(3): 183-194
-
(2009)
Cancer Cell
, vol.16
, Issue.3
, pp. 183-194
-
-
Fridlender, Z.G.1
Sun, J.2
Kim, S.3
Kapoor, V.4
Cheng, G.5
Ling, L.6
Worthen, G.S.7
Albelda, S.M.8
-
15
-
-
67449165640
-
Update of phase II study of DMXAA (AS1404) combined with carboplatin and paclitaxel in recurrent ovarian cancer
-
Gabra H, Jameson M (2007) Update of phase II study of DMXAA (AS1404) combined with carboplatin and paclitaxel in recurrent ovarian cancer. Eur J Cancer Suppl 5(4): 319-319
-
(2007)
Eur J Cancer Suppl
, vol.5
, Issue.4
, pp. 319-319
-
-
Gabra, H.1
Jameson, M.2
-
16
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
DOI 10.1126/science.1082504
-
Garcia-Barros M, Paris F, Cordon-Cardo C, Lyden D, Rafii S, Haimovitz-Friedman A, Fuks Z, Kolesnick R (2003) Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 300: 1155-1159 (Pubitemid 36583102)
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1155-1159
-
-
Garcia-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
Lyden, D.4
Rafii, S.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Kolesnick, R.8
-
17
-
-
33751320565
-
Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-b type i receptor kinase in vivo
-
Ge R, Rajeev V, Ray P, Lattime E, Rittling S, Medicherla S, Protter A, Murphy A, Chakravarty J, Dugar S, Schreiner G, Barnard N, Reiss M (2006) Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-b type I receptor kinase In vivo. Clin Cancer Res 12(14): 4315-4330
-
(2006)
Clin Cancer Res
, vol.12
, Issue.14
, pp. 4315-4330
-
-
Ge, R.1
Rajeev, V.2
Ray, P.3
Lattime, E.4
Rittling, S.5
Medicherla, S.6
Protter, A.7
Murphy, A.8
Chakravarty, J.9
Dugar, S.10
Schreiner, G.11
Barnard, N.12
Reiss, M.13
-
18
-
-
38849181724
-
Contaminating cells alter gene signatures in whole organ versus laser capture microdissected tumors: A comparison of experimental breast cancers and their lymph node metastases
-
DOI 10.1007/s10585-007-9105-7
-
Harrell J, Dye W, Harvell D, Sartorius C, Horwitz K (2008) Contaminating cells alter gene signatures in whole organ vs laser capture microdissected tumors: a comparison of experimental breast cancers and their lymph node metastases. Clin Exp Metastasis 25(1): 81-88 (Pubitemid 351191228)
-
(2008)
Clinical and Experimental Metastasis
, vol.25
, Issue.1
, pp. 81-88
-
-
Harrell, J.C.1
Dye, W.W.2
Harvell, D.M.E.3
Sartorius, C.A.4
Horwitz, K.B.5
-
19
-
-
51349131016
-
Endometrialperitoneal interactions during endometriotic lesion establishment
-
Hull ML, Escareno CR, Godsland JM, Doig JR, Johnson CM, Phillips SC, Smith SK, Tavare S, Print CG, Charnock-Jones DS (2008) Endometrialperitoneal interactions during endometriotic lesion establishment. Am J Pathol 173(3): 700-715
-
(2008)
Am J Pathol
, vol.173
, Issue.3
, pp. 700-715
-
-
Hull, M.L.1
Escareno, C.R.2
Godsland, J.M.3
Doig, J.R.4
Johnson, C.M.5
Phillips, S.C.6
Smith, S.K.7
Tavare, S.8
Print, C.G.9
Charnock-Jones, D.S.10
-
20
-
-
56349142086
-
Immune modulation by melanoma-derived factors
-
Ilkovitch D, Lopez DM (2008) Immune modulation by melanoma-derived factors. Exp Dermatol 17: 977-985
-
(2008)
Exp Dermatol
, vol.17
, pp. 977-985
-
-
Ilkovitch, D.1
Lopez, D.M.2
-
21
-
-
29244466134
-
+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma
-
DOI 10.1158/0008-5472.CAN-05-1658
-
Jassar AS, Suzuki E, Kapoor V, Sun J, Silverberg MB, Cheung L, Burdick MD, Strieter RM, Ching L-M, Kaiser LR, Albelda SM (2005) Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma. Cancer Res 65(24): 11752-11761 (Pubitemid 41821737)
-
(2005)
Cancer Research
, vol.65
, Issue.24
, pp. 11752-11761
-
-
Jassar, A.S.1
Suzuki, E.2
Kapoor, V.3
Sun, J.4
Silverberg, M.B.5
Cheung, L.6
Burdick, M.D.7
Strieter, R.M.8
Ching, L.-M.9
Kaiser, L.R.10
Albelda, S.M.11
-
22
-
-
0033083206
-
Stimulation of tumors to synthesize tumor necrosis factor-α in situ using 5,6-dimethylxanthenone-4-acetic acid: A novel approach to cancer therapy
-
Joseph WR, Cao Z, Mountjoy KG, Marshall ES, Baguley BC, Ching L-M (1999) Stimulation of tumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: a novel approach to cancer therapy. Cancer Res 59: 633-638 (Pubitemid 29076061)
-
(1999)
Cancer Research
, vol.59
, Issue.3
, pp. 633-638
-
-
Joseph, W.R.1
Cao, Z.2
Mountjoy, K.G.3
Marshall, E.S.4
Baguley, B.C.5
Ching, L.-M.6
-
23
-
-
0037805549
-
Basement membranes: Structure, assembly and role in tumour angiogenesis
-
DOI 10.1038/nrc1094
-
Kalluri R (2003) Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer 3(6): 422-433 (Pubitemid 37328846)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.6
, pp. 422-433
-
-
Kalluri, R.1
-
24
-
-
0035266136
-
Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci
-
Kanwar JR, Kanwar RK, Pandey S, Ching LM, Krissansen GW (2001) Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci. Cancer Res 61(5): 1948-1956 (Pubitemid 32692012)
-
(2001)
Cancer Research
, vol.61
, Issue.5
, pp. 1948-1956
-
-
Kanwar, J.R.1
Kanwar, R.K.2
Pandey, S.3
Ching, L.-M.4
Krissansen, G.W.5
-
25
-
-
78650722060
-
Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes
-
Kowanetz M, Wu X, Lee J, Tan M, Hagenbeek T, Qu X, Yu L, Ross J, Korsisaari N, Cao T, Bou-Reslan H, Kallop D, Weimer R, Ludlam MJC, Kaminker JS, Modrusan Z, van Bruggen N, Peale FV, Carano R, Meng YG, Ferrara N (2010) Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes. Proc Natl Acad Sci USA 107(50): 21248-21255
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.50
, pp. 21248-21255
-
-
Kowanetz, M.1
Wu, X.2
Lee, J.3
Tan, M.4
Hagenbeek, T.5
Qu, X.6
Yu, L.7
Ross, J.8
Korsisaari, N.9
Cao, T.10
Bou-Reslan, H.11
Kallop, D.12
Weimer, R.13
Mjc, L.14
Kaminker, J.S.15
Modrusan, Z.16
Van Bruggen, N.17
Peale, F.V.18
Carano, R.19
Meng, Y.G.20
Ferrara, N.21
more..
-
26
-
-
0031858141
-
Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs
-
Lash CJ, Li AE, Rutland M, Baguley BC, Zwi LJ, Wilson WR (1998) Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs. Br J Cancer 78(4): 439-445 (Pubitemid 28360629)
-
(1998)
British Journal of Cancer
, vol.78
, Issue.4
, pp. 439-445
-
-
Lash, C.J.1
Li, A.E.2
Rutland, M.3
Baguley, B.C.4
Zwi, L.J.5
Wilson, W.R.6
-
27
-
-
0026531756
-
High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma
-
Lienard D, Ewalenko P, Delmotte JJ, Renard N, Lejeune FJ (1992) High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J Clin Oncol 10(1): 52-60
-
(1992)
J Clin Oncol
, vol.10
, Issue.1
, pp. 52-60
-
-
Lienard, D.1
Ewalenko, P.2
Delmotte, J.J.3
Renard, N.4
Lejeune, F.J.5
-
28
-
-
41949104685
-
Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver
-
Lloyd CM, Phillips ARJ, Cooper GJS, Dunbar PR (2008) Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver. J Immunol Methods 334: 70-81
-
(2008)
J Immunol Methods
, vol.334
, pp. 70-81
-
-
Lloyd, C.M.1
Phillips, A.R.J.2
Cooper, G.J.S.3
Dunbar, P.R.4
-
29
-
-
0027869680
-
Anticancer drug sensitivity profiles of new and established melanoma cell lines
-
Marshall ES, Holdaway KM, Shaw JH, Finlay GJ, Mathews JH, Baguley BC (1993) Anticancer drug sensitivity profiles of new and established melanoma cell lines. Oncol Res 5: 301-309 (Pubitemid 24113422)
-
(1993)
Oncology Research
, vol.5
, Issue.8
, pp. 301-309
-
-
Marshall, E.S.1
Holdaway, K.M.2
Shaw, J.H.F.3
Finlay, G.J.4
Matthews, J.H.L.5
Baguley, B.C.6
-
30
-
-
57449103348
-
Randomised phase II study of ASA404 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer
-
McKeage MJ, Von Pawel J, Reck M, Jameson MB, Rosenthal MA, Sullivan R, Gibbs D, Mainwaring PN, Serke M, Lafitte JJ, Chouaid C, Freitag L, Quoix E (2008) Randomised phase II study of ASA404 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer. Br J Cancer 99(12): 2006-2012
-
(2008)
Br J Cancer
, vol.99
, Issue.12
, pp. 2006-2012
-
-
McKeage, M.J.1
Von Pawel, J.2
Reck, M.3
Jameson, M.B.4
Rosenthal, M.A.5
Sullivan, R.6
Gibbs, D.7
Mainwaring, P.N.8
Serke, M.9
Lafitte, J.J.10
Chouaid, C.11
Freitag, L.12
Quoix, E.13
-
31
-
-
33745989541
-
Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses
-
DOI 10.1200/JCO.2005.05.2498
-
Moschos SJ, Edington HD, Land SR, Rao UN, Jukic D, Shipe-Spotloe J, Kirkwood JM (2006) Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses. J Clin Oncol 24(19): 3164-3171 (Pubitemid 46638955)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.19
, pp. 3164-3171
-
-
Moschos, S.J.1
Edington, H.D.2
Land, S.R.3
Rao, U.N.4
Jukic, D.5
Shipe-Spotloe, J.6
Kirkwood, J.M.7
-
32
-
-
45549085803
-
An anti-transforming growth factor b antibody suppresses metastasis via cooperative effects on multiple cell compartments
-
Nam J-S, Terabe M, Mamura M, Kang M-J, Chae H, Stuelten C, Kohn E, Tang B, Sabzevari H, Anver MR, Lawrence S, Danielpour D, Lonning S, Berzofsky JA, Wakefield LM (2008) An anti-transforming growth factor b antibody suppresses metastasis via cooperative effects on multiple cell compartments. Cancer Res 68(10): 3835-3843
-
(2008)
Cancer Res
, vol.68
, Issue.10
, pp. 3835-3843
-
-
Nam, J.-S.1
Terabe, M.2
Mamura, M.3
Kang, M.-J.4
Chae, H.5
Stuelten, C.6
Kohn, E.7
Tang, B.8
Sabzevari, H.9
Anver, M.R.10
Lawrence, S.11
Danielpour, D.12
Lonning, S.13
Berzofsky, J.A.14
Wakefield, L.M.15
-
33
-
-
34548090017
-
Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity labeling
-
DOI 10.1021/jm0702175
-
Palmer BD, Henare K, Woon S-T, Sutherland R, Reddy C, Wang L-CS, Kieda C, Ching L-M (2007) Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity Labeling. J Med Chem 50(16): 3757-3764 (Pubitemid 47292039)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.16
, pp. 3757-3764
-
-
Palmer, B.D.1
Henare, K.2
Woon, S.-T.3
Sutherland, R.4
Reddy, C.5
Wang, L.-C.S.6
Kieda, C.7
Ching, L.-M.8
-
34
-
-
0033817283
-
Determinants of anti-vascular action by combretastatin A-4 phosphate: Role of nitric oxide
-
Parkins CS, Holder AL, Hill SA, Chaplin DJ, Tozer GM (2000) Determinants of anti-vascular action by combretastatin A-4 phosphate: role of nitric oxide. Br J Cancer 83(6): 811-816
-
(2000)
Br J Cancer
, vol.83
, Issue.6
, pp. 811-816
-
-
Parkins, C.S.1
Holder, A.L.2
Hill, S.A.3
Chaplin, D.J.4
Tozer, G.M.5
-
35
-
-
10744228405
-
Immunotherapy of melanoma
-
DOI 10.1016/j.semcancer.2003.09.001
-
Parmiani G, Castelli C, Rivoltini L, Casati C, Tully GA, Novellino L, Patuzzo A, Tosi D, Anichini A, Santinami M (2003) Immunotherapy of melanoma. Sem Cancer Biol 13(6): 391-400 (Pubitemid 38156130)
-
(2003)
Seminars in Cancer Biology
, vol.13
, Issue.6
, pp. 391-400
-
-
Parmiani, G.1
Castelli, C.2
Rivoltini, L.3
Casati, C.4
Tully, G.A.5
Novellino, L.6
Patuzzo, A.7
Tosi, D.8
Anichini, A.9
Santinami, M.10
-
36
-
-
77952399799
-
Phase II study on the addition of ASA404 (vadimezan; 5,6- dimethylxanthenone-4-acetic acid) to docetaxel in CRMPC
-
Pili R, Rosenthal MA, Mainwaring PN, Van Hazel G, Srinivas S, Dreicer R, Goel S, Leach J, Wong S, Clingan P (2010) Phase II study on the addition of ASA404 (vadimezan; 5,6-dimethylxanthenone-4-acetic acid) to docetaxel in CRMPC. Clin Cancer Res 16(10): 2906-2914
-
(2010)
Clin Cancer Res
, vol.16
, Issue.10
, pp. 2906-2914
-
-
Pili, R.1
Rosenthal, M.A.2
Mainwaring, P.N.3
Van Hazel, G.4
Srinivas, S.5
Dreicer, R.6
Goel, S.7
Leach, J.8
Wong, S.9
Clingan, P.10
-
37
-
-
0026100365
-
Potential antitumour agents. 61. Structure-activity relationships for in vivo colon 38 activity among disusbstituted 9-oxo-9H-xanthene-4-acetic acids
-
Rewcastle GW, Atwell GJ, Zhuang L, Baguley BC, Denny WA (1991) Potential antitumour agents. 61. Structure-activity relationships for in vivo colon 38 activity among disusbstituted 9-oxo-9H-xanthene-4-acetic acids. J Med Chem 34(1): 217-221
-
(1991)
J Med Chem
, vol.34
, Issue.1
, pp. 217-221
-
-
Rewcastle, G.W.1
Atwell, G.J.2
Zhuang, L.3
Baguley, B.C.4
Denny, W.A.5
-
38
-
-
40749154865
-
IFN-β-dependent inhibition of tumor growth by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
DOI 10.1089/jir.2007.0992
-
Roberts ZJ, Ching L-M, Vogel SN (2008) IFN-b-dependent inhibition of tumor growth by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). J Interferon Cytokine Res 28(3): 133-139 (Pubitemid 351380153)
-
(2008)
Journal of Interferon and Cytokine Research
, vol.28
, Issue.3
, pp. 133-139
-
-
Roberts, Z.J.1
Ching, L.-M.2
Vogel, S.N.3
-
39
-
-
34447330454
-
The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis
-
DOI 10.1084/jem.20061845
-
Roberts ZJ, Goutagny N, Perera P-Y, Kato H, Kumar H, Kawai T, Akira S, Savan R, van Echo D, Fitzgerald KA, Young HA, Ching L-M, Vogel SN (2007) The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis. J Exp Med 204(7): 1559-1569 (Pubitemid 47049627)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.7
, pp. 1559-1569
-
-
Roberts, Z.J.1
Goutagny, N.2
Perera, P.-Y.3
Kato, H.4
Kumar, H.5
Kawai, T.6
Akira, S.7
Savan, R.8
Van Echo, D.9
Fitzgerald, K.A.10
Young, H.A.11
Ching, L.-M.12
Vogel, S.N.13
-
40
-
-
20044395957
-
Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and montanide ISA 51 for patients with resected stages III and IV melanoma
-
DOI 10.1200/JCO.2005.01.128
-
Sanderson K, Scotland R, Lee P, Liu D, Groshen S, Snively J, Sian S, Nichol G, Davis T, Keler T, Yellin M, Weber J (2005) Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and montanide ISA 51 for patients with resected stages III and IV melanoma. J Clin Oncol 23(4): 741-750 (Pubitemid 46224173)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 741-750
-
-
Sanderson, K.1
Scotland, R.2
Lee, P.3
Liu, D.4
Groshen, S.5
Snively, J.6
Sian, S.7
Nichol, G.8
Davis, T.9
Keler, T.10
Yellin, M.11
Weber, J.12
-
41
-
-
68249125541
-
MRI-based characterization of vascular disruption by 5,6- dimethylxanthenone-acetic acid in gliomas
-
Seshadri M, Ciesielski MJ (2009) MRI-based characterization of vascular disruption by 5,6-dimethylxanthenone-acetic acid in gliomas. J Cereb Blood Flow Metab 29(8): 1373-1382
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, Issue.8
, pp. 1373-1382
-
-
Seshadri, M.1
Ciesielski, M.J.2
-
42
-
-
33745960743
-
Activity of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid against human head and neck carcinoma xenografts
-
DOI 10.1593/neo.06295
-
Seshadri M, Mazurchuk R, Spernyak JA, Bhattacharya A, Rustum YM, Bellnier DA (2006) Activity of the vascular-disrupting agent 5,6-dimethylxanthenone-4- acetic acid against human head and neck carcinoma xenografts. Neoplasia 8(7): 534-542 (Pubitemid 44061308)
-
(2006)
Neoplasia
, vol.8
, Issue.7
, pp. 534-542
-
-
Seshadri, M.1
Mazurchuk, R.2
Spernyak, J.A.3
Bhattacharya, A.4
Rustum, Y.M.5
Bellnier, D.A.6
-
43
-
-
70350220627
-
Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents
-
Shaked Y, Tang T, Woloszynek J, Daenen LG, Man S, Xu P, Cai S-R, Arbeit JM, Voest EE, Chaplin DJ, Smythe J, Harris A, Nathan P, Judson I, Rustin G, Bertolini F, Link DC, Kerbel RS (2009) Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents. Cancer Res 69(19): 7524-7528
-
(2009)
Cancer Res
, vol.69
, Issue.19
, pp. 7524-7528
-
-
Shaked, Y.1
Tang, T.2
Woloszynek, J.3
Daenen, L.G.4
Man, S.5
Xu, P.6
Cai, S.-R.7
Arbeit, J.M.8
Voest, E.E.9
Chaplin, D.J.10
Smythe, J.11
Harris, A.12
Nathan, P.13
Judson, I.14
Rustin, G.15
Bertolini, F.16
Link, D.C.17
Kerbel, R.S.18
-
44
-
-
10344234206
-
Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence
-
DOI 10.1002/ijc.20569
-
Smith CL, Dunbar PR, Mirza F, Palmowski MJ, Shepherd D, Gilbert SC, Coulie P, Schneider J, Hoffman E, Hawkins R, Harris AL, Cerundolo V (2005) Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence. Int J Cancer 113(2): 259-266 (Pubitemid 39628316)
-
(2005)
International Journal of Cancer
, vol.113
, Issue.2
, pp. 259-266
-
-
Smith, C.L.1
Dunbar, P.R.2
Mirza, F.3
Palmowski, M.J.4
Shepherd, D.5
Gilbert, S.C.6
Coulie, P.7
Schneider, J.8
Hoffman, E.9
Hawkins, R.10
Harris, A.L.11
Cerundolo, V.12
-
45
-
-
70449636444
-
Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
-
van Zijl F, Mair M, Csiszar A, Schneller D, Zulehner G, Huber H, Eferl R, Beug H, Dolznig H, Mikulits W (2009) Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge. Oncogene 28(45): 4022-4033
-
(2009)
Oncogene
, vol.28
, Issue.45
, pp. 4022-4033
-
-
Van Zijl, F.1
Mair, M.2
Csiszar, A.3
Schneller, D.4
Zulehner, G.5
Huber, H.6
Eferl, R.7
Beug, H.8
Dolznig, H.9
Mikulits, W.10
-
46
-
-
80053202190
-
G-CSF supplementation with chemotherapy can promote revascularization and subsequent tumor regrowth: Prevention by a CXCR4 antagonist
-
Voloshin T, Gingis-Velitski S, Bril R, Benayoun L, Munster M, Milsom C, Man S, Kerbel RS, Shaked Y (2011) G-CSF supplementation with chemotherapy can promote revascularization and subsequent tumor regrowth: prevention by a CXCR4 antagonist. Blood 118(12): 3426-3435
-
(2011)
Blood
, vol.118
, Issue.12
, pp. 3426-3435
-
-
Voloshin, T.1
Gingis-Velitski, S.2
Bril, R.3
Benayoun, L.4
Munster, M.5
Milsom, C.6
Man, S.7
Kerbel, R.S.8
Shaked, Y.9
-
47
-
-
67650485823
-
Neutrophil influx and chemokine production during the early phases of the antitumor response to the vascular disrupting Agent DMXAA (ASA404)
-
Wang L-CS, Thomsen L, Sutherland R, Reddy CB, Tijono SM, Chen C-JJ, Angel CE, Dunbar PR, Ching L-M (2009) Neutrophil influx and chemokine production during the early phases of the antitumor response to the vascular disrupting Agent DMXAA (ASA404). Neoplasia 11(8): 793-803
-
(2009)
Neoplasia
, vol.11
, Issue.8
, pp. 793-803
-
-
Wang, L.-C.S.1
Thomsen, L.2
Sutherland, R.3
Reddy, C.B.4
Tijono, S.M.5
Chen, C.-J.J.6
Angel, C.E.7
Dunbar, P.R.8
Ching, L.-M.9
-
48
-
-
33746905529
-
Inhibition of DMXAA-induced tumor necrosis factor production in murine splenocyte cultures by NF-κB inhibitors
-
Wang LC, Woon S-T, Baguley BC, Ching LM (2006) Inhibition of DMXAAinduced tumor necrosis factor production in murine splenocyte cultures by NF-kappa-b inhibitors. Oncol Res 16(1): 1-14 (Pubitemid 44195045)
-
(2006)
Oncology Research
, vol.16
, Issue.1
, pp. 1-14
-
-
Wang, J.-C.S.1
Woon, S.-T.2
Baguley, B.C.3
Ching, L.-M.4
-
49
-
-
79955517032
-
TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice
-
Welford AF, Biziato D, Coffelt SB, Nucera S, Fisher M, Pucci F, Di Serio C, Naldini L, De Palma M, Tozer GM, Lewis CE (2011) TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice. J Clin Invest 121(5): 1969-1973
-
(2011)
J Clin Invest
, vol.121
, Issue.5
, pp. 1969-1973
-
-
Welford, A.F.1
Biziato, D.2
Coffelt, S.B.3
Nucera, S.4
Fisher, M.5
Pucci, F.6
Di Serio, C.7
Naldini, L.8
De Palma, M.9
Tozer, G.M.10
Lewis, C.E.11
-
50
-
-
0037726779
-
NF-kappa B activation in vivo in both host and tumour cells by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
DOI 10.1016/S0959-8049(03)00196-5
-
Woon S-T, Zwain S, Schooltink MA, Newth A, Baguley BC, Ching L-M (2003) NF-kappa B activation in vivo in both host and tumour cells by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Eur J Cancer 39(8): 1176-1183 (Pubitemid 36555878)
-
(2003)
European Journal of Cancer
, vol.39
, Issue.8
, pp. 1176-1183
-
-
Woon, S.-T.1
Zwain, S.2
Schooltink, M.A.3
Newth, A.L.4
Baguley, B.C.5
Ching, L.-M.6
|