Induction of STAT and NFκB activation by the antitumor agents 5,6-dimethylxanthenone-4-acetic acid and flavone acetic acid in a murine macrophage cell line

Biochemical Pharmacology

Volumn 58, Issue 7, 1999, Pages 1173-1181

  Ching, Lai Ming ^a   Young, Howard A ^b   Eberly, Kara ^b   Yu, Cheng Rong ^b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Antitumor; NF B; STAT; Transcription factors; Xanthenones

Indexed keywords

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; CYCLOHEXIMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; LIPOPOLYSACCHARIDE; MITOFLAXONE; TRANSCRIPTION FACTOR; 5,6 DIMETHYLXANTHENONEACETIC ACID; 5,6-DIMETHYLXANTHENONEACETIC ACID; ANTINEOPLASTIC AGENT; BETA INTERFERON; DNA BINDING PROTEIN; FLAVONOID; PROTEIN SYNTHESIS INHIBITOR; STAT1 PROTEIN; STAT1 PROTEIN, MOUSE; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; XANTHENE DERIVATIVE; XANTHONE DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; INTERFERON INDUCTION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECT; METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE; CYCLOHEXIMIDE; DNA-BINDING PROTEINS; FLAVONOIDS; INTERFERON-BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; PROTEIN SYNTHESIS INHIBITORS; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; XANTHENES; XANTHONES;

EID: 0033201439     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00194-X     Document Type: Article

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