(+)-Rutamarin as a dual inducer of both GLUT4 translocation and expression efficiently ameliorates glucose homeostasis in insulin-resistant mice

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Zhang, Yu ^a   Zhang, Haitao ^a   Yao, Xin gang ^a   Shen, Hong ^a   Chen, Jing ^a   Li, Chenjing ^a   Chen, Lili ^a   Zheng, Mingyue ^a   Ye, Jiming ^b   Hu, Lihong ^a   Shen, Xu ^a   Jiang, Hualiang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b RMIT UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 4; INSULIN; METFORMIN; NATURAL PRODUCT; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; RETINOID X RECEPTOR ALPHA; RUTAMARIN; UNCLASSIFIED DRUG; BENZOPYRAN DERIVATIVE; GLUCOSE; PTPN1 PROTEIN, MOUSE; SLC2A4 PROTEIN, MOUSE;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CRYSTALLOGRAPHY; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; GENE EXPRESSION; GENE TRANSLOCATION; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MOUSE; NONHUMAN; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; ANIMAL; C57BL MOUSE; CELL STRAIN 3T3; CELL STRAIN HEK293; CHO CELL; CRICETULUS; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; HOMEOSTASIS; METABOLISM; MOUSE MUTANT; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSIOLOGY; PROTEIN TRANSPORT;

MUS;

ANIMALS; BENZOPYRANS; CHO CELLS; CRICETINAE; CRICETULUS; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HEK293 CELLS; HOMEOSTASIS; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; NIH 3T3 CELLS; PROTEIN TRANSPORT; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1;

EID: 84863258370     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031811     Document Type: Article

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