Polysaccharide isolated from Triticum aestivum stimulates insulin release from pancreatic cells via the ATP-sensitive K + channel

International Journal of Molecular Medicine

Volumn 29, Issue 5, 2012, Pages 913-919

  Lee, Sun Hee ^a   Lim, Sung Won ^a   Lee, Young Mi ^b   Lee, Hoi Seon ^c   Kim, Dae Ki ^a  

^a Chonbuk National University Medical School   (South Korea)

^b Wonkwang University   (South Korea)

^c Chonbuk National University   (South Korea)

Author keywords

Calcium influx; Diabetes mellitus; Insulin secretion; Pancreatic cells; Triticum aestivum

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DIAZOXIDE; GLUCOSE; INSULIN; PLANT EXTRACT; POLYSACCHARIDE; PROINSULIN; TRITICUM AESTIVUM EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TRITICUM AESTIVUM;

ANIMALS; BLOOD GLUCOSE; CELL LINE; CELLS, CULTURED; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; KATP CHANNELS; MALE; MICE; MICE, INBRED C57BL; PLANT EXTRACTS; POLYSACCHARIDES; POTASSIUM; RATS; RATS, WISTAR; TRITICUM;

EID: 84863246816     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.905     Document Type: Article

References (42)

1. Beardsall K, Yuen K, Williams R and Dunger D: Applied physiology glucose control. Curr Paediatr 13: 543-548, 2003.
2. Ferrer JC, Favre C, Gomis RR, Fernández-Novell JM, et al: Control of glycogen deposition. FEBS Lett 546: 127-132, 2003. (Pubitemid 36782293)
3. Herrington J, Zhou YP, Bugianesi RM, et al: Blockers of the delayed-rectifier potassium current in pancreatic beta-cells enhance glucose-dependent insulin secretion. Diabetes 55: 1034-1042, 2006. (Pubitemid 44100179)
4. Stumvoll M, Goldstein BJ and van Haeften TW: Type 2 diabetes: principles of pathogenesis and therapy. Lancet 365: 1333-1346, 2005.
5. Yang SN and Berggren PO: β-cell CaV channel regulation in physiology and pathophysiology. Am J Physiol Endocrinol Metab 288: 16-28, 2005.
6. Geng X, Li L, Bottino R, et al: Antidiabetic sulfonylurea stimulates insulin secretion independently of plasma membrane KATP channels. Am J Physiol Endocrinol Metab 293: 293-301, 2007.
7. Del-Prato S and Pulizzi N: The place of sulfonylureas in the therapy for type 2 diabetes mellitus. Metabolism 55: 20-27, 2006.
8. Rang HP, Dale MM and Rittar JM: The endocrine system pharmacology. In: Pharmacology. Longman Group Ltd., London. pp504-508, 1991.
9. Liu S: Intake of refined carbohydrates and whole grain foods in relation to risk of type 2 diabetes mellitus and coronary heart disease. J Am Coll Nutr 21: 298-306, 2002.
10. Hallfrisch J, Facn and Behall KM: Mechanisms of the effects of grains on insulin and glucose responses. J Am Coll Nutr 19 (Suppl 3): S320-S325, 2000.
11. Nandini CD, Salimath PM and Sambaiah K: Effect of dietary fibres on constituents of complex carbohydrates in streptozotocin induced diabetic rat tissues. Mol Cell Biochem 236: 133-138, 2002. (Pubitemid 34846142)
12. Dahech I, Belghith KS, Hamden K, Feki A, Belghith H and Mejdoub H: Antidiabetic activity of levan polysaccharide in alloxan-induced diabetic rats. Int J Biol Macromol 49: 742-746, 2011.
13. Hu F, Li X, Zhao L, Feng S and Wang C: Antidiabetic properties of purified polysaccharide from Hedysarum polybotrys. Can J Physiol Pharmacol 88: 64-72, 2010.
14. Lee SH, Lee YM, Lee HS and Kim DK: Anti-oxidative and anti-hyperglycemia effects of Triticum aestivum wheat sprout water extracts on the streptozotocin-induced diabetic mice. Kor J Pharmacogn 40: 408-414, 2009.
15. Giacco R, Brighenti F, Parillo M, et al: Characteristics of some wheat-based foods of the Italian diet in relation to their influence on postprandial glucose metabolism in patients with type 2 diabetes. Br J Nutr 85: 33-40, 2001. (Pubitemid 32156578)
16. Vaaler S, Hanssen KF, Dahl-Jørgensen K, Frølich W, Aaseth J, Odegaard B and Aagenaes O: Diabetic control is improved by guar gum and wheat bran supplementation. Diabet Med 3: 230-233, 1986. (Pubitemid 16068494)
17. Eddouks M, Maghrani M and Michel JB: Hypoglycaemic effect of Triticum repens P. Beauv. in normal and diabetic rats. J Ethnopharmacol 102: 228-232, 2005. (Pubitemid 41483563)
18. Nagaoka H: Treatment of germinated wheat to increase levels of GABA and IP6 catalyzed by endogenous enzymes. Biotechnol Prog 21: 405-410, 2005.
19. Kim YW, Kim KH, Choi HJ and Lee DS: Anti-diabetic activity of beta-glucans and their enzymatically hydrolyzed oligosaccharides from Agaricus blazei. Biotechnol Lett 27: 483-487, 2005.
20. Zhang D, Fujii I, Lin C, et al: The stimulatory activities of polysaccharide compounds derived from algae extracts on insulin secretion in vitro. Biol Pharm Bull 31: 921-924, 2008. (Pubitemid 351731997)
21. Nielsen DA, Welsh M, Casadaban MJ and Steiner DF: Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects glucose and cyclic AMP on the transcription of insulin mRNA. J Biol Chem 260: 13585-13589, 1985. (Pubitemid 16192311)
22. Luo AX, He XJ, Zhou SD, Fan YJ, He T and Chun Z: In vitro antioxidant activities of a water-soluble polysaccharide derived from Dendrobium nobile L. Extracts. Int J Biol Macromol 45: 359-363, 2009.
23. Staub AM: Removal of proteins: Sevag method. Methods Carbohydr Chem 5: 5-6, 1965.
24. Dubois M, Gilles KA, Hamilton JK, Rebers PA and Smith F: Colorimetric method for determination of sugars and related substances. Anal Chem 28: 350-356, 1956.
25. Herchuelz A and Malaisse WJ: Regulation of calcium fluxes in pancreatic islets: association between calcium and insulin release. J Physiol 283: 409-424, 1978. (Pubitemid 9048118)
26. + channel in mouse pancreatic beta-cells. Pflugers Arch 407: 493-499, 1986.
27. Sharp GWG: The adenylate cyclase-cyclic AMP system in islets of Langerhans and its role in the control of insulin release. Diabetologia 16: 287-297, 1979.
28. Leibowitz MD, Biswas C, Brady EJ, et al: A novel insulin secretagogue is a phosphodiesterase inhibitor. Diabetes 44: 67-74, 1995.
29. +-ATP channel-dependent pathway. Eur J Endocrinol 152: 617-677, 2005.
30. Grill V, Radtke M, Qvigstad E, Kollind M and Björklund A: Beneficial effects of K-ATP channel openers in diabetes: an update on mechanisms and clinical experiences. Diabetes Obes Metab 11: 143-148, 2009.
31. Hellman B, Sehlin J and Taljedal IB: Calcium and secretion: distinction between two pools glucose-sensitive calcium in pancreatic islets. Science 24: 1421-1423, 1976.
32. Gireesh G, Thomas SK, Joseph B and Paulose CS: Antihyperglycemic and insulin secretory activity of Costus pictus leaf extract in streptozotocin- induced diabetic rats and in vitro pancreatic islet culture. J Ethnopharmacol 123: 470-474, 2009.
33. Latha M, Pari L, Sitasawad S and Bhonde R: Insulin-secretagogue activity and cytoprotective role of the traditional antidiabetic plant Scopariadulcis (sweet broom weed). Life Sci 75: 2003-2014, 2004. (Pubitemid 39092564)
34. Liu B, Asare-Anane H, Al-Romaiyan A, Huang G, Amiel SA, Jones PM and Persaud SJ: Characterization of the insulinotropic activity of an aqueous extract of Gymnemasylvestre in mouse beta-cells and human islets of Langerhans. Cell Physiol Biochem 23: 125-132, 2009.
35. Sezik E, Aslan M, Yesilada E and Ito S: Hypoglycemic activity of Gentiana olivieri and isolation of the active constituent through bioassay-directed fractionation techniques. Life Sci 76: 1223-1238, 2005. (Pubitemid 40092137)
36. Souza A, Mbatchi B and Herchuelz A: Induction of insulin secretion by an aqueous extract of Tabernanhte iboga Baill. (Apocynaceae) in rat pancreatic islets of Langerhans. J Ethnopharmacol 133: 1015-1020, 2011.
37. Ardestani A and Yazdanparast R: Flavonoids as potential therapeutic agents for type 1 diabetes. Med Hypotheses 69: 955-956, 2007.
38. Eidi A, Eidi M and Sokhteh M: Effect of fenugreek (Trigonella foenumgraecum L) seeds on serum parameters in normal and streptozotocin-induced diabetic rats. Nutr Res 27: 728-733, 2007. (Pubitemid 350086770)
39. Tapola N, Karvonen H, Niskanen L, Mikola M and Sarkkinen E: Glycemic responses of oat bran products in type 2 diabetic patients. Nutr Metab Cardiovasc Dis 15: 255-261, 2005. (Pubitemid 41190982)
40. Dahech I, Belghith KS, Hamden K, Feki A, Belghith H and Mejdoub H: Oral administration of levan polysaccharide reduces the alloxan-induced oxidative stress in rats. Int J Biol Macromol 49: 942-947, 2011.
41. Kim H, Stote KS, Behall KM, Spears K, Vinyard B and Conway JM: Glucose and insulin responses to whole grain breakfasts varying in soluble fiber, beta-glucan: a dose response study in obese women with increased risk for insulin resistance. Eur J Nutr 48: 170-175, 2009.
42. Chen X, Bai X, Liu Y, et al: Anti-diabetic effects of water extract and crude polysaccharides from tuberous root of Liriope spicata var. prolifera in mice. J Ethnopharmacol 12: 205-209, 2009.