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Volumn 20, Issue 3, 2012, Pages 209-223

A mini review of nanosuspensions development

Author keywords

Discrimination; Nanosuspensions; Production techniques; Routes of administration; Special features; Stable measures

Indexed keywords

NANOCRYSTAL; SILIBININ; SOLVENT; STABILIZING AGENT;

EID: 84863229909     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2011.645161     Document Type: Review
Times cited : (49)

References (80)
  • 2
    • 52949128719 scopus 로고    scopus 로고
    • Comparison of nanosuspensions and hydroxypropyl-beta-cyclodextrin complex of melarsoprol: Pharmacokinetics and tissue distribution in mice
    • Ben Zirar S, Astier A, Muchow M, Gibaud S. (2008). Comparison of nanosuspensions and hydroxypropyl-beta-cyclodextrin complex of melarsoprol: pharmacokinetics and tissue distribution in mice. Eur J Pharm Biopharm, 70, 649-656.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 649-656
    • Ben Zirar, S.1    Astier, A.2    Muchow, M.3    Gibaud, S.4
  • 3
    • 0032903302 scopus 로고    scopus 로고
    • HPLC determination of clofazimine in tissues and serum of mice after intravenous administration of nanocrystalline or liposomal formulations
    • Borner K, Hartwig H, Leitzke S, Hahn H, Müler RH, Ehlers S. (1999). HPLC determination of clofazimine in tissues and serum of mice after intravenous administration of nanocrystalline or liposomal formulations. Int J Antimicrob Agents, 11, 75-79.
    • (1999) Int. J. Antimicrob Agents , vol.11 , pp. 75-79
    • Borner, K.1    Hartwig, H.2    Leitzke, S.3    Hahn, H.4    Müler, R.H.5    Ehlers, S.6
  • 4
    • 77955052417 scopus 로고    scopus 로고
    • Miconazole nanosuspensions: Influence of formulation variables on particle size reduction and physical stability
    • Cerdeira AM, Mazzotti M, Gander B. (2010). Miconazole nanosuspensions: Influence of formulation variables on particle size reduction and physical stability. Int J Pharm, 396, 210-218.
    • (2010) Int. J. Pharm. , vol.396 , pp. 210-218
    • Cerdeira, A.M.1    Mazzotti, M.2    Gander, B.3
  • 6
    • 67349138612 scopus 로고    scopus 로고
    • Two-stage microfluidization combined with ultrafiltration treatment for chitosan mass production and molecular weight manipulation
    • Chen RH, Tsai ML, Tseng LZ. (2009). Two-stage microfluidization combined with ultrafiltration treatment for chitosan mass production and molecular weight manipulation. Carbohyd Polym, 77, 767-772.
    • (2009) Carbohyd Polym , vol.77 , pp. 767-772
    • Chen, R.H.1    Tsai, M.L.2    Tseng, L.Z.3
  • 7
    • 0034110573 scopus 로고    scopus 로고
    • Synthesis of nanoparticles with novel technology: High-gravity reactive precipitation
    • Chen JF, Wang YH, Guo F, Wang XM, Zheng C. (2000). Synthesis of nanoparticles with novel technology: high-gravity reactive precipitation. Ind Eng Chem Res, 39, 948-954.
    • (2000) Ind. Eng. Chem. Res. , vol.39 , pp. 948-954
    • Chen, J.F.1    Wang, Y.H.2    Guo, F.3    Wang, X.M.4    Zheng, C.5
  • 8
    • 51349121937 scopus 로고    scopus 로고
    • A facile nanoaggregation strategy for oral delivery of hydrophobic drugs by utilizing acid-base neutralization reactions
    • Chen H, Wan J, Wang Y, Mou D, Liu H, Xu H, Yang X. (2008). A facile nanoaggregation strategy for oral delivery of hydrophobic drugs by utilizing acid-base neutralization reactions. Nanotechnology, 19, 375104.
    • (2008) Nanotechnology , vol.19 , pp. 375104
    • Chen, H.1    Wan, J.2    Wang, Y.3    Mou, D.4    Liu, H.5    Xu, H.6    Yang, X.7
  • 9
    • 0030148294 scopus 로고    scopus 로고
    • Interaction of macro-and micromixing on particle size distribution in reaction precipitation
    • Chen JF, Zheng C, Chen GT. (1996). Interaction of macro-and micromixing on particle size distribution in reaction precipitation. Chem Eng Sci, 51, 1957-1966.
    • (1996) Chem. Eng. Sci. , vol.51 , pp. 1957-1966
    • Chen, J.F.1    Zheng, C.2    Chen, G.T.3
  • 11
    • 84863296052 scopus 로고    scopus 로고
    • Synthesis of ultrafine calcium carbonate
    • Patent No ZL95105343.4
    • Chen JF, Zhou XM, Wang YH, Zheng C. (1998). Synthesis of ultrafine calcium carbonate. Chinese Patent No. ZL95105343.4.
    • (1998) Chinese
    • Chen, J.F.1    Zhou, X.M.2    Wang, Y.H.3    Zheng, C.4
  • 12
    • 84863296233 scopus 로고
    • Ultrafine particle synthesis by high-gravity reactive precipitation
    • Patent No.95105344.2
    • Chen JF, Zhou XM, Zheng C. (1995). Ultrafine particle synthesis by high-gravity reactive precipitation. Chinese Patent No. 95105344.2.
    • (1995) Chinese
    • Chen, J.F.1    Zhou, X.M.2    Zheng, C.3
  • 13
    • 59949091288 scopus 로고    scopus 로고
    • Evaluation of aerosol delivery of nanosuspension for pre-clinical pulmonary drug delivery
    • Chiang PC, Alsup JW, Lai Y, Hu Y, Heyde BR, Tung D. (2009). Evaluation of Aerosol Delivery of Nanosuspension for Pre-clinical Pulmonary Drug Delivery. Nanoscale Res Lett, 4, 254-261.
    • (2009) Nanoscale Res. Lett. , vol.4 , pp. 254-261
    • Chiang, P.C.1    Alsup, J.W.2    Lai, Y.3    Hu, Y.4    Heyde, B.R.5    Tung, D.6
  • 15
    • 67349199134 scopus 로고    scopus 로고
    • Advantages of celecoxib nanosuspension formulation and transformation into tablets
    • Dolenc A, Kristl J, Baumgartner S, Planinsek O. (2009). Advantages of celecoxib nanosuspension formulation and transformation into tablets. Int J Pharm, 376, 204-212.
    • (2009) Int. J. Pharm. , vol.376 , pp. 204-212
    • Dolenc, A.1    Kristl, J.2    Baumgartner, S.3    Planinsek, O.4
  • 18
    • 0012248471 scopus 로고
    • Higee-A status report
    • Fowler R. (1989). Higee-a status report. Chem Eng, 35, 456-473.
    • (1989) Chem. Eng. , vol.35 , pp. 456-473
    • Fowler, R.1
  • 19
    • 64249128053 scopus 로고    scopus 로고
    • Formulation development and evaluation of metronidazole magnetic nanosuspension as a magnetic-targeted and polymericcontrolled drug delivery system
    • Formulation development and evaluation of metronidazole magnetic nanosuspension as a magnetic-targeted and polymericcontrolled drug delivery system. J Magn Magn Mater, 321, 1580-1585.
    • J. Magn. Magn. Mater. , vol.321 , pp. 1580-1585
  • 20
    • 77956398535 scopus 로고    scopus 로고
    • Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer
    • Gao Y, Li Z, Sun M, Li H, Guo C, Cui J, Li A, Cao F, Xi Y, Lou H, Zhai G. (2010). Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer. Drug Dev Ind Pharm, 36, 1225-1234.
    • (2010) Drug Dev. Ind. Pharm. , vol.36 , pp. 1225-1234
    • Gao, Y.1    Li, Z.2    Sun, M.3    Li, H.4    Guo, C.5    Cui, J.6    Li, A.7    Cao, F.8    Xi, Y.9    Lou, H.10    Zhai, G.11
  • 21
    • 41349120910 scopus 로고    scopus 로고
    • Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions
    • Gao L, Zhang D, Chen M, Duan C, Dai W, Jia L, Zhao W. (2008b). Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions. Int J Pharm, 355, 321-327.
    • (2008) Int. J. Pharm. , vol.355 , pp. 321-327
    • Gao, L.1    Zhang, D.2    Chen, M.3    Duan, C.4    Dai, W.5    Jia, L.6    Zhao, W.7
  • 22
    • 0343340404 scopus 로고    scopus 로고
    • Synchronous visual and RTD study on liquid ?ow inrotating packed-bed contactor
    • Guo K, Guo F, Feng YD, Chen JF, Zheng C, Gardner NC. (2000). Synchronous visual and RTD study on liquid ?ow inrotating packed-bed contactor. Chem Eng Sci, 55, 1699-1706.
    • (2000) Chem. Eng. Sci. , vol.55 , pp. 1699-1706
    • Guo, K.1    Guo, F.2    Feng, Y.D.3    Chen, J.F.4    Zheng, C.5    Gardner, N.C.6
  • 23
    • 1142303337 scopus 로고    scopus 로고
    • What is the true solubility advantage for amorphous pharmaceuticals?
    • Hancock BC, Parks M. (2000). What is the true solubility advantage for amorphous pharmaceuticals? Pharm Res, 17, 397-404.
    • (2000) Pharm. Res. , vol.17 , pp. 397-404
    • Hancock, B.C.1    Parks, M.2
  • 24
    • 33750089277 scopus 로고    scopus 로고
    • Preparation and in vitro/in vivo evaluation of nano-sized crystals for dissolution rate enhancement of ucb- 35440-3, a highly dosed poorly water-soluble weak base
    • Hecq J, Deleers M, Fanara D, Vranckx H, Boulanger P, Le Lamer S, Amighi K. (2006). Preparation and in vitro/in vivo evaluation of nano-sized crystals for dissolution rate enhancement of ucb- 35440-3, a highly dosed poorly water-soluble weak base. Eur J Pharm Biopharm, 64, 360-368.
    • (2006) Eur. J. Pharm. Biopharm. , vol.64 , pp. 360-368
    • Hecq, J.1    Deleers, M.2    Fanara, D.3    Vranckx, H.4    Boulanger, P.5    Le Lamer, S.6    Amighi, K.7
  • 25
    • 0035910873 scopus 로고    scopus 로고
    • Production and characterization of mucoadhesive nanosuspensions for the formulation of bupravaquone
    • Jacobs C, Kayser O, Müler RH. (2001). Production and characterization of mucoadhesive nanosuspensions for the formulation of bupravaquone. Int J Pharm, 214, 3-7.
    • (2001) Int. J. Pharm. , vol.214 , pp. 3-7
    • Jacobs, C.1    Kayser, O.2    Müler, R.H.3
  • 27
    • 0033970268 scopus 로고    scopus 로고
    • Nanosuspensions for the formulation of aphidicolin to improve drug targeting effects against leishmania infected macrophages
    • Kayser O. (2000). Nanosuspensions for the formulation of aphidicolin to improve drug targeting effects against leishmania infected macrophages. Int J Pharm, 196, 253-256.
    • (2000) Int. J. Pharm. , vol.196 , pp. 253-256
    • Kayser, O.1
  • 28
    • 0035910888 scopus 로고    scopus 로고
    • A new approach for targeting to Cryptosporidium parvum using mucoadhesive nanosuspensions: Research and applications
    • Kayser O. (2001). A new approach for targeting to Cryptosporidium parvum using mucoadhesive nanosuspensions: research and applications. Int J Pharm, 214, 83-85.
    • (2001) Int. J. Pharm. , vol.214 , pp. 83-85
    • Kayser, O.1
  • 30
    • 0034756945 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease
    • Kawashima Y, Lehr CM. (2001). Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J Pharmacol Exp Ther, 299, 775-781.
    • (2001) J. Pharmacol Exp Ther , vol.299 , pp. 775-781
    • Kawashima, Y.1    Lehr, C.M.2
  • 31
    • 34548049483 scopus 로고    scopus 로고
    • Nanosizing-oral formulation development and biopharmaceutical evaluation
    • Kesisoglou F, Panmai S, Wu Y. (2007). Nanosizing-oral formulation development and biopharmaceutical evaluation. Adv Drug Deliv Rev, 59, 631-644.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 631-644
    • Kesisoglou, F.1    Panmai, S.2    Wu, Y.3
  • 32
    • 5344234787 scopus 로고    scopus 로고
    • The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs
    • Kipp JE. (2004). The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs. Int J Pharm, 284, 109-122.
    • (2004) Int. J. Pharm. , vol.284 , pp. 109-122
    • Kipp, J.E.1
  • 33
    • 33645030096 scopus 로고    scopus 로고
    • Preparation and evaluation of nanosuspensions for enhancing the dissolution of poorly soluble drugs
    • Kocbek P, Baumgartner S, Kristl J. (2006). Preparation and evaluation of nanosuspensions for enhancing the dissolution of poorly soluble drugs. Int J Pharm, 312, 179-186.
    • (2006) Int. J. Pharm. , vol.312 , pp. 179-186
    • Kocbek, P.1    Baumgartner, S.2    Kristl, J.3
  • 34
    • 67349199134 scopus 로고    scopus 로고
    • Advantages of celecoxib nanosuspension formulation and transformation into tablets
    • Kristl J, Dolenc A, Baumgartner S, Planinsek O. (2009). Advantages of celecoxib nanosuspension formulation and transformation into tablets. Int J Pharm, 376, 204-212.
    • (2009) Int. J. Pharm. , vol.376 , pp. 204-212
    • Kristl, J.1    Dolenc, A.2    Baumgartner, S.3    Planinsek, O.4
  • 35
    • 67349098845 scopus 로고    scopus 로고
    • Diclofenac nanosuspensions: influence of preparation procedure nd crystal form on drug dissolution behaviour
    • Lai F, Sinico C, Ennas G, Marongiu F, Marongiu G, Fadda AM. (2009). Diclofenac nanosuspensions: influence of preparation procedure nd crystal form on drug dissolution behaviour. Int J Pharm, 373, 124-132.
    • (2009) Int. J. Pharm. , vol.373 , pp. 124-132
    • Lai, F.1    Sinico, C.2    Ennas, G.3    Marongiu, F.4    Marongiu, G.5    Fadda, A.M.6
  • 37
    • 64249128053 scopus 로고    scopus 로고
    • Formulation development and evaluation of metronidazole magnetic nanosuspension as a magnetic-targeted and polymeric-controlled drug delivery system
    • Latha S, Selvamani P, Kumar CS, Sharavanan P, Suganya G, Beniwal VS, Rao PR. (2009). Formulation development and evaluation of metronidazole magnetic nanosuspension as a magnetic-targeted and polymeric-controlled drug delivery system. J Mang Mang Mater, 321, 1580-1585.
    • (2009) J. Mang Mang Mater , vol.321 , pp. 1580-1585
    • Latha, S.1    Selvamani, P.2    Kumar, C.S.3    Sharavanan, P.4    Suganya, G.5    Beniwal, V.S.6    Rao, P.R.7
  • 38
    • 33344464389 scopus 로고    scopus 로고
    • Critical freezing rate in freeze drying nanocrystal dispersions
    • Lee J, Cheng Y. (2006). Critical freezing rate in freeze drying nanocrystal dispersions. J Control Release, 111, 185-192.
    • (2006) J. Control Release , vol.111 , pp. 185-192
    • Lee, J.1    Cheng, Y.2
  • 39
    • 84863259961 scopus 로고    scopus 로고
    • Water-insoluble drug formation. interpharm press
    • Liu R, ed.). Particle size reduction
    • Lee RW, Mcshane J, Shaw JM, Wood RW. (2000). Particle size reduction. In: Liu R, ed. Water-Insoluble Drug Formation. Interpharm Press, Buffalo Grove, 455-492.
    • (2000) Buffalo Grove , pp. 455-492
    • Lee, R.W.1    McShane, J.2    Shaw, J.M.3    Wood, R.W.4
  • 42
    • 38049088818 scopus 로고    scopus 로고
    • Thiolated chitosan nanoparticles: Transfection study in the Caco-2 differentiated cell culture
    • Martien R, Loretz B, Sandbichler AM, Schnüch AB. (2008). Thiolated chitosan nanoparticles: transfection study in the Caco-2 differentiated cell culture. Nanotechnology, 19, 045101.
    • (2008) Nanotechnology , vol.19 , pp. 045101
    • Martien, R.1    Loretz, B.2    Sandbichler, A.M.3    Schnüch, A.B.4
  • 43
    • 61349095957 scopus 로고    scopus 로고
    • Development of an oral rutin nanocrystal formulation
    • Mauludin R, Müler RH, Keck CM. (2009). Development of an oral rutin nanocrystal formulation. Int J Pharm, 370, 202-209.
    • (2009) Int. J. Pharm. , vol.370 , pp. 202-209
    • Mauludin, R.1    Müler, R.H.2    Keck, C.M.3
  • 44
    • 0037312695 scopus 로고    scopus 로고
    • Nanosizing: A formulation approach for poorly-water-soluble compounds
    • Merisko-Liversidge E, Liversidge GG, Cooper ER. (2003). Nanosizing: a formulation approach for poorly-water-soluble compounds. Eur J Pharm Sci, 18, 113-120.
    • (2003) Eur J Pharm Sci , vol.18 , pp. 113-120
    • Merisko-Liversidge, E.1    Liversidge, G.G.2    Cooper, E.R.3
  • 45
    • 21644468027 scopus 로고    scopus 로고
    • Insulin nanoparticles: A novel formulation approach for poorly water soluble Zn-insulin
    • Merisko-Liversidge E, McGurk SL, Liversidge GG. (2004). Insulin nanoparticles: a novel formulation approach for poorly water soluble Zn-insulin. Pharm Res, 21, 1545-1553.
    • (2004) Pharm Res , vol.21 , pp. 1545-1553
    • Merisko-Liversidge, E.1    McGurk, S.L.2    Liversidge, G.G.3
  • 46
    • 62749150964 scopus 로고    scopus 로고
    • Production and characterization of Hesperetin nanosuspensions for dermal delivery
    • Mishra PR, Al Shaal L, Müler RH, Keck CM. (2009). Production and characterization of Hesperetin nanosuspensions for dermal delivery. Int J Pharm, 371, 182-189.
    • (2009) Int. J. Pharm. , vol.371 , pp. 182-189
    • Mishra, P.R.1    Al Shaal, L.2    Müler, R.H.3    Keck, C.M.4
  • 47
    • 4644309307 scopus 로고    scopus 로고
    • Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology
    • Möchwitzer J, Achleitner G, Pomper H, Müler RH. (2004). Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology. Eur J Pharm Biopharm, 58, 615-619.
    • (2004) Eur J Pharm Biopharm , vol.58 , pp. 615-619
    • Möchwitzer, J.1    Achleitner, G.2    Pomper, H.3    Müler, R.H.4
  • 48
    • 79958005215 scopus 로고    scopus 로고
    • Potent dried drug nanosuspensions for oral bioavailability enhancement of poorly soluble drugs with pH-dependent solubility
    • Mou D, Chen H, Wan J, Xu H, Yang X. (2011). Potent dried drug nanosuspensions for oral bioavailability enhancement of poorly soluble drugs with pH-dependent solubility. Int J Pharm, 413, 237-244.
    • (2011) Int. J. Pharm. , vol.413 , pp. 237-244
    • Mou, D.1    Chen, H.2    Wan, J.3    Xu, H.4    Yang, X.5
  • 51
    • 0037177516 scopus 로고    scopus 로고
    • Buparvaquone mucoadhesive nanosuspension: Preparation, optimisation and long-term stability
    • Müler RH, Jacobs C. (2002). Buparvaquone mucoadhesive nanosuspension: preparation, optimisation and long-term stability. Int J Pharm, 237, 151-161.
    • (2002) Int. J. Pharm. , vol.237 , pp. 151-161
    • Müler, R.H.1    Jacobs, C.2
  • 53
    • 4544275025 scopus 로고    scopus 로고
    • Challenges and solutions for the delivery of biotech drugs-A review of drug nanocrystal technology and lipid nanoparticles
    • Muller RH, Keck CM. (2004). Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanoparticles. J Biotechnol, 113, 151-170.
    • (2004) J. Biotechnol , vol.113 , pp. 151-170
    • Muller, R.H.1    Keck, C.M.2
  • 54
    • 28444461830 scopus 로고    scopus 로고
    • Drug nanocrystals of poorly soluble drugs produced by high pressure homogenization
    • Muller RH, Keck CM. (2006). Drug nanocrystals of poorly soluble drugs produced by high pressure homogenization. Eur J Pharm Biopharm, 62, 3-16.
    • (2006) Eur J Pharm Biopharm , vol.62 , pp. 3-16
    • Muller, R.H.1    Keck, C.M.2
  • 55
    • 0342897023 scopus 로고    scopus 로고
    • Nanosuspensions for the formulation of poorly soluble drugs-I. Preparation by a size-reduction technique
    • Muller RH, Peters K. (1998). Nanosuspensions for the formulation of poorly soluble drugs-I. Preparation by a size-reduction technique. Int J Pharm, 160, 229-237.
    • (1998) Int. J. Pharm. , vol.160 , pp. 229-237
    • Muller, R.H.1    Peters, K.2
  • 56
    • 0037400585 scopus 로고    scopus 로고
    • New micelle-like polymer aggregates made from PEI-PLGA diblock copolymers: Micellar characteristics and cellular uptake
    • Nam YS, Kang HS, Park JY, Park TG, Han SH, Chang IS. (2003). New micelle-like polymer aggregates made from PEI-PLGA diblock copolymers: micellar characteristics and cellular uptake. Biomaterials, 24, 2053-2059.
    • (2003) Biomaterials , vol.24 , pp. 2053-2059
    • Nam, Y.S.1    Kang, H.S.2    Park, J.Y.3    Park, T.G.4    Han, S.H.5    Chang, I.S.6
  • 59
    • 0031402134 scopus 로고    scopus 로고
    • Mucoadhesion of colloidal particulate systems in the gasrointesinal tract
    • Ponchel G, Montisci MJ, Dembri A. (1997). Mucoadhesion of colloidal particulate systems in the gasrointesinal tract. Eur J Pharm Biopharm, 4, 25-31
    • (1997) Eur J Pharm Biopharm , vol.4 , pp. 25-3
    • Ponchel, G.1    Montisci, M.J.2    Dembri, A.3
  • 60
    • 4544383493 scopus 로고    scopus 로고
    • Nanosuspensions in drug delivery
    • Rabinow BE. (2004). Nanosuspensions in drug delivery. Nat Rev Drug Discov, 3, 785-796.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 785-796
    • Rabinow, B.E.1
  • 63
    • 0032885450 scopus 로고    scopus 로고
    • Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs
    • Serajuddin AT. (1999). Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs. J Pharm Sci, 88, 1058-1066.
    • (1999) J. Pharm Sci , vol.88 , pp. 1058-1066
    • Serajuddin, A.T.1
  • 65
    • 40949138845 scopus 로고    scopus 로고
    • Development of ascorbyl palmitate nanocrystals applying the nanosuspension technology
    • Teeranachaideekul V, Junyaprasert VB, Souto EB, Müler RH. (2008). Development of ascorbyl palmitate nanocrystals applying the nanosuspension technology. Int J Pharm, 354, 227-234.
    • (2008) Int. J. Pharm. , vol.354 , pp. 227-234
    • Teeranachaideekul, V.1    Junyaprasert, V.B.2    Souto, E.B.3    Müler, R.H.4
  • 67
    • 53949092998 scopus 로고    scopus 로고
    • Top-down production of drug nanocrystals: Nanosuspension stabilization, miniaturization and transformation into solid products
    • Van den Mooter G, Van Eerdenbrugh B, Augustijns P. (2008a). Top-down production of drug nanocrystals: Nanosuspension stabilization, miniaturization and transformation into solid products. Int J Pharm, 364, 64-75.
    • (2008) Int. J. Pharm. , vol.364 , pp. 64-75
    • Van Den Mooter, G.1    Van Eerdenbrugh, B.2    Augustijns, P.3
  • 68
    • 48849111481 scopus 로고    scopus 로고
    • Drying of crystalline drug nanosuspensions-The importance of surface hydrophobicity on dissolution behavior upon redispersion
    • Van den Mooter G, Van Eerdenbrugh B, Froyen L, Van Humbeeck J, Martens JA, Augustijns P. (2008b). Drying of crystalline drug nanosuspensions-The importance of surface hydrophobicity on dissolution behavior upon redispersion. Eur J Pharm Sci, 35, 127-135.
    • (2008) Eur J Pharm Sci , vol.35 , pp. 127-135
    • Van Den Mooter, G.1    Van Eerdenbrugh, B.2    Froyen, L.3    Van Humbeeck, J.4    Martens, J.A.5    Augustijns, P.6
  • 69
    • 69549119873 scopus 로고    scopus 로고
    • A comparative study of topdown and bottom-up approaches for the preparation of micro/ nanosuspensions
    • Verma S, Gokhale R, Burgess DJ. (2009a). A comparative study of topdown and bottom-up approaches for the preparation of micro/ nanosuspensions. Int J Pharm, 380, 216-222.
    • (2009) Int. J. Pharm. , vol.380 , pp. 216-222
    • Verma, S.1    Gokhale, R.2    Burgess, D.J.3
  • 70
    • 67649660193 scopus 로고    scopus 로고
    • Quality by design approach to understand the process of nanosuspension preparation
    • Verma S, Lan Y, Gokhale R, Burgess DJ. (2009b). Quality by design approach to understand the process of nanosuspension preparation. Int J Pharm, 377, 185-198.
    • (2009) Int. J. Pharm. , vol.377 , pp. 185-198
    • Verma, S.1    Lan, Y.2    Gokhale, R.3    Burgess, D.J.4
  • 72
    • 79957971638 scopus 로고    scopus 로고
    • Docetaxelloaded- lipid-based-nanosuspensions (DTX-LNS): Preparation, pharmacokinetics, tissue distribution and antitumor activity
    • Wang L, Liu Z, Liu D, Liu C, Juan Z, Zhang N. (2011a). Docetaxelloaded- lipid-based-nanosuspensions (DTX-LNS): preparation, pharmacokinetics, tissue distribution and antitumor activity. Int J Pharm, 413, 194-201.
    • (2011) Int. J. Pharm. , vol.413 , pp. 194-201
    • Wang, L.1    Liu, Z.2    Liu, D.3    Liu, C.4    Juan, Z.5    Zhang, N.6
  • 75
    • 33751392855 scopus 로고    scopus 로고
    • Applications of microfluidics in chemical biology
    • Weibel DB, Whitesides GM. (2006). Applications of microfluidics in chemical biology. Curr Opin Chem Biol, 10, 584-591.
    • (2006) Curr Opin Chem Biol , vol.10 , pp. 584-591
    • Weibel, D.B.1    Whitesides, G.M.2
  • 76
    • 77953543307 scopus 로고    scopus 로고
    • Preparation of stable nitrendipine nanosuspensions using the precipitationultrasonication method for enhancement of dissolution and oral bioavailability
    • Xia D, Quan P, Piao H, Piao H, Sun S, Yin Y, Cui F. (2010). Preparation of stable nitrendipine nanosuspensions using the precipitationultrasonication method for enhancement of dissolution and oral bioavailability. Eur J Pharm Sci, 40, 325-334.
    • (2010) Eur J Pharm Sci , vol.40 , pp. 325-334
    • Xia, D.1    Quan, P.2    Piao, H.3    Piao, H.4    Sun, S.5    Yin, Y.6    Cui, F.7
  • 77
    • 38349162256 scopus 로고    scopus 로고
    • Preparation and characterization of intravenously injectable nimodipine nanosuspension
    • Xiong R, Lu W, Li J, Wang P, Xu R, Chen T. (2008). Preparation and characterization of intravenously injectable nimodipine nanosuspension. Int J Pharm, 350, 338-343.
    • (2008) Int. J. Pharm. , vol.350 , pp. 338-343
    • Xiong, R.1    Lu, W.2    Li, J.3    Wang, P.4    Xu, R.5    Chen, T.6
  • 78
    • 77951652999 scopus 로고    scopus 로고
    • Comparison of bioavailability of amorphous versus crystalline itraconazole nanoparticles via pulmonary administration in rats
    • Yang W, Johnston KP, Williams RO 3rd. (2010). Comparison of bioavailability of amorphous versus crystalline itraconazole nanoparticles via pulmonary administration in rats. Eur J Pharm Biopharm, 75, 33-41.
    • (2010) Eur J Pharm Biopharm , vol.75 , pp. 33-41
    • Yang, W.1    Johnston, K.P.2    Williams III, R.O.3
  • 79
    • 77952741121 scopus 로고    scopus 로고
    • Preparation and cytotoxic activity of hydroxycamptothecin nanosuspensions
    • Zhao YX, Hua HY, Chang M, Liu WJ, Zhao Y, Liu HM. (2010). Preparation and cytotoxic activity of hydroxycamptothecin nanosuspensions. Int J Pharm, 392, 64-71.
    • (2010) Int. J. Pharm. , vol.392 , pp. 64-71
    • Zhao, Y.X.1    Hua, H.Y.2    Chang, M.3    Liu, W.J.4    Zhao, Y.5    Liu, H.M.6


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