Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression

Translational Psychiatry

Volumn 2, Issue , 2012, Pages

  Guo, M ^a   Lu, Y ^b   Garza, J C ^a   Li, Y ^c   Chua, S C ^d   Zhang, W ^b   Lu, B ^a   Lu, X Y ^a,e  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c The University of Alabama at Birmingham   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e GLAXOSMITHKLINE   (China)

Author keywords

Behavioral depression; GluN2B subunit; Glutamatergic neurons; Leptin receptor; NMDA receptors; Synaptic depression

Indexed keywords

CORTICOSTERONE; GLUTAMIC ACID; INSULIN; LEPTIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; EMPTY SPIRACLES HOMEOBOX PROTEINS; GLUTAMINE; HOMEODOMAIN PROTEIN; LEPTIN RECEPTOR; LEPTIN RECEPTOR, MOUSE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR2B NMDA RECEPTOR; TRANSCRIPTION FACTOR;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BODY WEIGHT; BRAIN NERVE CELL; CONTROLLED STUDY; DEPRESSION; DRUG SENSITIVITY; ESCAPE BEHAVIOR; FEMALE; FOREBRAIN; GLUTAMATERGIC NERVE CELL; GROWTH; HIPPOCAMPUS; HOPELESSNESS; HORMONE ACTION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LEARNED HELPLESSNESS; LOCOMOTION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PHENOTYPE; PREFRONTAL CORTEX; PSYCHOSOCIAL WITHDRAWAL; SIGNAL TRANSDUCTION; TASTE PREFERENCE; ANIMAL; AROUSAL; BLOOD; BRAIN CORTEX; EXPLORATORY BEHAVIOR; GENETICS; HYPOTHALAMUS; MOTIVATION; MOTOR ACTIVITY; MOUSE MUTANT; NERVE CELL; ORIENTATION; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SOCIAL DOMINANCE; SOCIAL ENVIRONMENT;

ANIMALS; AROUSAL; CEREBRAL CORTEX; CORTICOSTERONE; DEPRESSION; DOMINANCE-SUBORDINATION; EXPLORATORY BEHAVIOR; GLUTAMINE; HELPLESSNESS, LEARNED; HIPPOCAMPUS; HOMEODOMAIN PROTEINS; HYPOTHALAMUS; INSULIN; LEPTIN; LONG-TERM SYNAPTIC DEPRESSION; MICE; MICE, KNOCKOUT; MOTIVATION; MOTOR ACTIVITY; NEURONS; ORIENTATION; PROSENCEPHALON; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, LEPTIN; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; SOCIAL ENVIRONMENT; TRANSCRIPTION FACTORS;

EID: 84863229399     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2012.9     Document Type: Article

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