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Volumn 20, Issue 14, 2012, Pages 4437-4442

Hyrtioreticulins A-E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus

(17) Yamanokuchi, Rumi a Imada, Kumiko a Miyazaki, Mitsue a Kato, Hikaru a Watanabe, Tadashi b Fujimuro, Masahiro b Saeki, Yasushi c Yoshinaga, Sosuke a Terasawa, Hiroaki a Iwasaki, Noriyuki d Rotinsulu, Henki e,f Losung, Fitje g Mangindaan, Remy E P g Namikoshi, Michio e De Voogd, Nicole J h Yokosawa, Hideyoshi i Tsukamoto, Sachiko a

a KUMAMOTO UNIVERSITY (Japan)

b KYOTO PHARMACEUTICAL UNIVERSITY (Japan)

c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (Japan)

d BRUKER DALTONIK GMBH (Germany)

e TOHOKU PHARMACEUTICAL UNIVERSITY (Japan)

f Faculty of Agriculture (Indonesia)

g SAM RATULANGI UNIVERSITY (Indonesia)

h NATURALIS BIODIVERSITY CENTER (Netherlands)

i AICHI GAKUIN UNIVERSITY (Japan)

Author keywords

Hyrtios reticulatus; Indole alkaloid; Marine sponge; Ubiquitin activating enzyme inhibitor

Indexed keywords

ENZYME INHIBITOR; HIMEIC ACID; HYRTIORETICULIN A; HYRTIORETICULIN B; HYRTIORETICULIN C; HYRTIORETICULIN D; HYRTIORETICULIN E; HYRTIOS RETICULATUS EXTRACT; INDOLE ALKALOID; LIGASE INHIBITOR; NATURAL PRODUCTS AND THEIR SYNTHETIC DERIVATIVES; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG BINDING SITE; DRUG ISOLATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HYRTIOS RETICULATUS; IC 50; SPONGE (PORIFERA); STRUCTURE ACTIVITY RELATION;

ANIMALS; ENZYME INHIBITORS; INDOLE ALKALOIDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PORIFERA; UBIQUITIN-ACTIVATING ENZYMES;

HYRTIOS;

EID: 84863217296 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.05.044 Document Type: Article

Times cited : (68)

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