Haploscleridamine, a novel tryptamine-derived alkaloid from a sponge of the order haplosclerida: An inhibitor of cathepsin K

Journal of Natural Products

Volumn 65, Issue 4, 2002, Pages 628-629

  Patil, Ashok D ^b   Freyer, Alan J ^a   Carte, Brad ^c   Taylor, Paul B ^a   Johnson, Randall K ^a   Faulkner, D John ^d  

^a GLAXOSMITHKLINE   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c S BIO Pte Ltd   (Singapore)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; CATHEPSIN K; ENZYME INHIBITOR; HALITOXIN; HAPLOSCLERIDAMINE; TRYPTAMINE; UNCLASSIFIED DRUG;

ANIMAL PRODUCT; ARTICLE; DRUG STRUCTURE; ENZYME INHIBITION; HAPLOSCLERIDA; IC 50; NONHUMAN; SPONGE (PORIFERA);

ALKALOIDS; ANIMALS; CATHEPSINS; CHROMATOGRAPHY, THIN LAYER; CYSTEINE PROTEINASE INHIBITORS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PALAU; PORIFERA; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TRYPTAMINES;

ANIMALIA; HAPLOSCLERIDA; PORIFERA;

EID: 0036239534     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np010500l     Document Type: Article

References (8)