Expression profile of hepatic genes in cynomolgus macaques bred in Cambodia, China, and Indonesia: Implications for cytochrome P450 genes

Drug Metabolism and Pharmacokinetics

Volumn 27, Issue 3, 2012, Pages 307-316

  Ise, Ryota ^a   Nakanishi, Yasuharu ^a   Kohara, Sakae ^a   Yamashita, Hiroyuki ^a   Yoshikawa, Tsuyoshi ^a   Iwasaki, Kazuhide ^a   Nagata, Ryoichi ^a   Fukuzaki, Koichiro ^a   Utoh, Masahiro ^a   Nakamura, Chika ^a   Yamazaki, Hiroshi ^b   Uno, Yasuhiro ^a  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Cynomolgus macaque; Cytochrome P450; Gene expression; Liver; Metabolic activity

Indexed keywords

CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; MITOCHONDRIAL DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREEDING; CAMBODIA; CHINA; CONTROLLED STUDY; CYTOCHROME P450 GENE; DNA MICROARRAY; ENZYME ACTIVITY; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE PROBE; HAPLOTYPE; HYDROXYLATION; INDONESIA; LIVER MICROSOME; MALE; NONHUMAN; PHENOTYPE; PHYLOGENETIC TREE; POLYMERASE CHAIN REACTION; RHESUS MONKEY; SEQUENCE ALIGNMENT; SEX DIFFERENCE; SPECIES DIFFERENCE;

EID: 84863204518     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-11-RG-133     Document Type: Article

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