Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 5, 2012, Pages

  Ruivo, Raquel ^a,b,h   Bellenchi, Gian Carlo ^c   Chen, Xiong ^a   Zifarelli, Giovanni ^d   Sagneá, Corinne ^a   Debacker, Cećile ^a   Pusch, Michael ^d   Supplisson, Steṕhane ^e,f,g   Gasnier, Bruno ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^d CNR   (Italy)

^e ECOLE NORMALE SUPÉRIEURE   (France)

^f CNRS   (France)

^g INSERM   (France)

^h UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BACTERIORHODOPSIN; CYSTEINE; CYSTINOSIN; DEUTERIUM; LYSOSOME ENZYME; PROTON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME BINDING; FEMALE; MUTAGENESIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTON TRANSPORT; STEADY STATE; SUBSTITUTION REACTION;

AMINO ACID SEQUENCE; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; BINDING SITES; HUMANS; LYSOSOMES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTONS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EUKARYOTA;

EID: 84863173801     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115581109     Document Type: Article

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