The Targeting of Cystinosin to the Lysosomal Membrane Requires a Tyrosine-based Signal and a Novel Sorting Motif

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 13314-13321

  Cherqui, Stéphanie ^b   Kalatzis, Vasiliki ^b   Trugnan, Germain ^a   Antignac, Corinne ^b  

^a HÔPITAL SAINT ANTOINE   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CELL MEMBRANES; CYTOLOGY; FLUORESCENCE; GENES; HYDROPHOBICITY; MUTAGENESIS;

LYSOSOMAL TRANSPORT DISORDERS;

PROTEINS;

CYSTINOSIN; CYSTINOSIN GREEN FLUORESCENT PROTEIN FUSION PROTEIN; HYBRID PROTEIN; LYSOSOMAL MEMBRANE PROTEIN 2; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CTNS PROTEIN, HUMAN; GLYCOPROTEIN; RECOMBINANT PROTEIN; TYROSINE;

AMINO ACID TRANSPORT; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CTNS GENE; CYSTINOSIS; GENE; GENE CONSTRUCT; GENE DELETION; GENETIC CODE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LYSOSOME MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN TARGETING; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DOG; GENETICS; GLYCOSYLATION; HELA CELL; INTRACELLULAR MEMBRANE; LYSOSOME; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; PROTEIN SECONDARY STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CYSTINOSIS; DOGS; GLYCOPROTEINS; GLYCOSYLATION; HELA CELLS; HUMANS; INTRACELLULAR MEMBRANES; LYSOSOMES; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANSFECTION; TYROSINE;

EID: 0035918290     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010562200     Document Type: Article

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