Skin tumor promotion by argemone oil/alkaloid in mice: Evidence for enhanced cell proliferation, ornithine decarboxylase, cyclooxygenase-2 and activation of MAPK/NF-κB pathway

Food and Chemical Toxicology

Volumn 48, Issue 1, 2010, Pages 132-138

  Ansari, Kausar M ^a   Das, Mukul ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Argemone oil; Cell proliferation; Mouse skin; Signaling pathways; Tumor promoter

Indexed keywords

ARGEMONE OIL; CYCLINE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; ORNITHINE DECARBOXYLASE; SANGUINARINE; STRESS ACTIVATED PROTEIN KINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; FOOD CONTAMINATION; KERATINOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS; SKIN TUMOR; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ALKALOIDS; ANIMALS; BENZOPHENANTHRIDINES; BLOTTING, WESTERN; CARCINOGENS; CELL COUNT; CELL NUCLEUS; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYTOSOL; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; ISOQUINOLINES; KERATINOCYTES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; ORNITHINE DECARBOXYLASE; PLANT EXTRACTS; PLANT OILS; SEEDS; SKIN; SKIN NEOPLASMS;

ARGEMONE; MUS;

EID: 72149112193     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.09.029     Document Type: Article

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