Nobilamides A-H, long-acting transient receptor potential vanilloid-1 (TRPV1) antagonists from mollusk-associated bacteria

Journal of Medicinal Chemistry

Volumn 54, Issue 11, 2011, Pages 3746-3755

  Lin, Zhenjian ^a   Reilly, Christopher A ^b   Antemano, Rowena ^e   Hughen, Ronald W ^c   Marett, Lenny ^a   Concepcion, Gisela P ^e   Haygood, Margo G ^f   Olivera, Baldomero M ^d   Light, Alan ^c   Schmidt, Eric W ^a,d  

^a Departments of Medicinal Chemistry   (United States)

^b Departments of Pharmacology and Toxicology   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF UTAH   (United States)

^e University of the Philippines Diliman   (Philippines)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A 3302 A; CAPSAICIN; NOBILAMIDE B; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1 ANTAGONIST;

ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; COVALENT BOND; HUMAN; HUMAN CELL; MOLLUSC; MOUSE; NONHUMAN; PAIN; SPINAL GANGLION; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM; CAPSAICIN; CELLS, CULTURED; DEPSIPEPTIDES; GANGLIA, SPINAL; GASTROPODA; HEK293 CELLS; HUMANS; MICE; MOLECULAR STRUCTURE; OLIGOPEPTIDES; PROTEIN BINDING; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; TRPV CATION CHANNELS;

EID: 79958106628     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm101621u     Document Type: Article

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