메뉴 건너뛰기




Volumn 11, Issue , 2011, Pages

Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine

Author keywords

endothelial cells; glioblastoma multiformevasculature normalizationliposomal drugs

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; CD31 ANTIGEN; DOCETAXEL; DOXORUBICIN; HOE 33342; IRINOPHORE C; IRINOTECAN; LIPID; LIPOSOME; NANOPARTICLE; PACLITAXEL; UNCLASSIFIED DRUG; VINCRISTINE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DNA BINDING PROTEIN; DRUG DERIVATIVE; RAG2 PROTEIN, MOUSE;

EID: 79953757824     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-124     Document Type: Article
Times cited : (52)

References (51)
  • 3
    • 0031924299 scopus 로고    scopus 로고
    • Characterization of angiogenesis and microcirculation of high-grade glioma: an intravital multifluorescence microscopic approach in the athymic nude mouse
    • 10.1097/00004647-199805000-00006, 9591843.
    • Vajkoczy P, Schilling L, Ullrich A, Schmiedek P, Menger MD. Characterization of angiogenesis and microcirculation of high-grade glioma: an intravital multifluorescence microscopic approach in the athymic nude mouse. J Cereb Blood Flow Metab 1998, 18:510-20. 10.1097/00004647-199805000-00006, 9591843.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 510-520
    • Vajkoczy, P.1    Schilling, L.2    Ullrich, A.3    Schmiedek, P.4    Menger, M.D.5
  • 4
    • 0029898758 scopus 로고    scopus 로고
    • Role of tumor vascular architecture in nutrient and drug delivery: an invasion percolation-based network model
    • 10.1006/mvre.1996.0031, 8992232.
    • Baish JW, Gazit Y, Berk DA, Nozue M, Baxter LT, Jain RK. Role of tumor vascular architecture in nutrient and drug delivery: an invasion percolation-based network model. Microvasc Res 1996, 51:327-46. 10.1006/mvre.1996.0031, 8992232.
    • (1996) Microvasc Res , vol.51 , pp. 327-346
    • Baish, J.W.1    Gazit, Y.2    Berk, D.A.3    Nozue, M.4    Baxter, L.T.5    Jain, R.K.6
  • 5
    • 0028025011 scopus 로고
    • Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows
    • Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res 1994, 54:4564-8.
    • (1994) Cancer Res , vol.54 , pp. 4564-4568
    • Yuan, F.1    Salehi, H.A.2    Boucher, Y.3    Vasthare, U.S.4    Tuma, R.F.5    Jain, R.K.6
  • 6
    • 0034470379 scopus 로고    scopus 로고
    • Vascular microenvironment in gliomas
    • 10.1023/A:1006474832189, 11245285.
    • Vajkoczy P, Menger MD. Vascular microenvironment in gliomas. J Neurooncol 2000, 50:99-108. 10.1023/A:1006474832189, 11245285.
    • (2000) J Neurooncol , vol.50 , pp. 99-108
    • Vajkoczy, P.1    Menger, M.D.2
  • 7
    • 39749156447 scopus 로고    scopus 로고
    • Irinophore C: a liposome formulation of irinotecan with substantially improved therapeutic efficacy against a panel of human xenograft tumors
    • 10.1158/1078-0432.CCR-07-0780, 18281556.
    • Ramsay EC, Anantha M, Zastre J, Meijs M, Zonderhuis J, Strutt D, Webb MS, Waterhouse D, Bally MB. Irinophore C: a liposome formulation of irinotecan with substantially improved therapeutic efficacy against a panel of human xenograft tumors. Clin Cancer Res 2008, 14:1208-17. 10.1158/1078-0432.CCR-07-0780, 18281556.
    • (2008) Clin Cancer Res , vol.14 , pp. 1208-1217
    • Ramsay, E.C.1    Anantha, M.2    Zastre, J.3    Meijs, M.4    Zonderhuis, J.5    Strutt, D.6    Webb, M.S.7    Waterhouse, D.8    Bally, M.B.9
  • 9
    • 32944466693 scopus 로고    scopus 로고
    • Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling
    • 10.1152/ajpheart.00616.2005, 16172161.
    • Baffert F, Le T, Sennino B, Thurston G, Kuo CJ, Hu-Lowe D, McDonald DM. Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling. Am J Physiol Heart Circ Physiol 2006, 290:H547-59. 10.1152/ajpheart.00616.2005, 16172161.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Baffert, F.1    Le, T.2    Sennino, B.3    Thurston, G.4    Kuo, C.J.5    Hu-Lowe, D.6    McDonald, D.M.7
  • 10
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy
    • 10.1038/nm0901-987, 11533692.
    • Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med 2001, 7:987-9. 10.1038/nm0901-987, 11533692.
    • (2001) Nat Med , vol.7 , pp. 987-989
    • Jain, R.K.1
  • 11
    • 0028966810 scopus 로고
    • Pharmacology of liposomal vincristine in mice bearing L1210 ascitic and B16/BL6 solid tumours
    • 10.1038/bjc.1995.98, 2033637, 7880728.
    • Mayer LD, Masin D, Nayar R, Boman NL, Bally MB. Pharmacology of liposomal vincristine in mice bearing L1210 ascitic and B16/BL6 solid tumours. Br J Cancer 1995, 71:482-8. 10.1038/bjc.1995.98, 2033637, 7880728.
    • (1995) Br J Cancer , vol.71 , pp. 482-488
    • Mayer, L.D.1    Masin, D.2    Nayar, R.3    Boman, N.L.4    Bally, M.B.5
  • 12
    • 61449133020 scopus 로고    scopus 로고
    • A comparative study on the anti-angiogenic effects of DNA-damaging and cytoskeletal-disrupting agents
    • 10.1007/s10456-009-9134-8, 19214765.
    • Mabeta P, Pepper MS. A comparative study on the anti-angiogenic effects of DNA-damaging and cytoskeletal-disrupting agents. Angiogenesis 2009, 12:81-90. 10.1007/s10456-009-9134-8, 19214765.
    • (2009) Angiogenesis , vol.12 , pp. 81-90
    • Mabeta, P.1    Pepper, M.S.2
  • 13
    • 7444229833 scopus 로고    scopus 로고
    • Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome
    • Chen Q, Tong S, Dewhirst MW, Yuan F. Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome. Mol Cancer Ther 2004, 3:1311-7.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1311-1317
    • Chen, Q.1    Tong, S.2    Dewhirst, M.W.3    Yuan, F.4
  • 14
    • 29344443996 scopus 로고    scopus 로고
    • Effect of repetitive administration of Doxorubicin-containing liposomes on plasma pharmacokinetics and drug biodistribution in a rat brain tumor model
    • 10.1158/1078-0432.CCR-05-1365, 2883876, 16361575.
    • Arnold RD, Mager DE, Slack JE, Straubinger RM. Effect of repetitive administration of Doxorubicin-containing liposomes on plasma pharmacokinetics and drug biodistribution in a rat brain tumor model. Clin Cancer Res 2005, 11:8856-65. 10.1158/1078-0432.CCR-05-1365, 2883876, 16361575.
    • (2005) Clin Cancer Res , vol.11 , pp. 8856-8865
    • Arnold, R.D.1    Mager, D.E.2    Slack, J.E.3    Straubinger, R.M.4
  • 15
    • 0036570056 scopus 로고    scopus 로고
    • Antivasculature effects of doxorubicin-containing liposomes in an intracranial rat brain tumor model
    • Zhou R, Mazurchuk R, Straubinger RM. Antivasculature effects of doxorubicin-containing liposomes in an intracranial rat brain tumor model. Cancer Res 2002, 62:2561-6.
    • (2002) Cancer Res , vol.62 , pp. 2561-2566
    • Zhou, R.1    Mazurchuk, R.2    Straubinger, R.M.3
  • 16
    • 39849089601 scopus 로고    scopus 로고
    • A novel liposomal irinotecan formulation with significant anti-tumour activity: use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention
    • 10.1016/j.ejpb.2007.08.011, 17904831.
    • Ramsay E, Alnajim J, Anantha M, Zastre J, Yan H, Webb M, Waterhouse D, Bally M. A novel liposomal irinotecan formulation with significant anti-tumour activity: use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention. Eur J Pharm Biopharm 2008, 68:607-17. 10.1016/j.ejpb.2007.08.011, 17904831.
    • (2008) Eur J Pharm Biopharm , vol.68 , pp. 607-617
    • Ramsay, E.1    Alnajim, J.2    Anantha, M.3    Zastre, J.4    Yan, H.5    Webb, M.6    Waterhouse, D.7    Bally, M.8
  • 17
    • 0025103345 scopus 로고
    • Liposomal vincristine preparations which exhibit decreased drug toxicity and increased activity against murine L1210 and P388 tumors
    • Mayer LD, Bally MB, Loughrey H, Masin D, Cullis PR. Liposomal vincristine preparations which exhibit decreased drug toxicity and increased activity against murine L1210 and P388 tumors. Cancer Res 1990, 50:575-9.
    • (1990) Cancer Res , vol.50 , pp. 575-579
    • Mayer, L.D.1    Bally, M.B.2    Loughrey, H.3    Masin, D.4    Cullis, P.R.5
  • 18
    • 0024354304 scopus 로고
    • Determination of subcutaneous tumor size in athymic (nude) mice
    • 10.1007/BF00300234, 2544306.
    • Tomayko MM, Reynolds CP. Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother Pharmacol 1989, 24:148-54. 10.1007/BF00300234, 2544306.
    • (1989) Cancer Chemother Pharmacol , vol.24 , pp. 148-154
    • Tomayko, M.M.1    Reynolds, C.P.2
  • 19
    • 0031814383 scopus 로고    scopus 로고
    • Measurement of perfusion rate in human melanoma xenografts by contrast-enhanced magnetic resonance imaging
    • 10.1002/mrm.1910400113, 9660558.
    • Lyng H, Dahle GA, Kaalhus O, Skretting A, Rofstad EK. Measurement of perfusion rate in human melanoma xenografts by contrast-enhanced magnetic resonance imaging. Magn Reson Med 1998, 40:89-98. 10.1002/mrm.1910400113, 9660558.
    • (1998) Magn Reson Med , vol.40 , pp. 89-98
    • Lyng, H.1    Dahle, G.A.2    Kaalhus, O.3    Skretting, A.4    Rofstad, E.K.5
  • 21
    • 53349171627 scopus 로고    scopus 로고
    • High-content imaging characterization of cell cycle therapeutics through in vitro and in vivo subpopulation analysis
    • 10.1158/1535-7163.MCT-08-0328, 18723491.
    • Low J, Huang S, Blosser W, Dowless M, Burch J, Neubauer B, Stancato L. High-content imaging characterization of cell cycle therapeutics through in vitro and in vivo subpopulation analysis. Mol Cancer Ther 2008, 7:2455-63. 10.1158/1535-7163.MCT-08-0328, 18723491.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2455-2463
    • Low, J.1    Huang, S.2    Blosser, W.3    Dowless, M.4    Burch, J.5    Neubauer, B.6    Stancato, L.7
  • 23
    • 59449093937 scopus 로고    scopus 로고
    • Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells
    • 10.1097/CAD.0b013e32831c14ec, 19209028.
    • Foroodi F, Duivenvoorden WC, Singh G. Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells. Anticancer Drugs 2009, 20:115-22. 10.1097/CAD.0b013e32831c14ec, 19209028.
    • (2009) Anticancer Drugs , vol.20 , pp. 115-122
    • Foroodi, F.1    Duivenvoorden, W.C.2    Singh, G.3
  • 24
    • 71449125258 scopus 로고    scopus 로고
    • Altered expression of proliferation-inducing and proliferation-inhibiting genes might contribute to acquired doxorubicin resistance in breast cancer cells
    • 10.1007/s12013-009-9058-3, 19593673.
    • Saleh EM, El-Awady RA, Abdel Alim MA, Abdel Wahab AH. Altered expression of proliferation-inducing and proliferation-inhibiting genes might contribute to acquired doxorubicin resistance in breast cancer cells. Cell Biochem Biophys 2009, 55:95-105. 10.1007/s12013-009-9058-3, 19593673.
    • (2009) Cell Biochem Biophys , vol.55 , pp. 95-105
    • Saleh, E.M.1    El-Awady, R.A.2    Abdel Alim, M.A.3    Abdel Wahab, A.H.4
  • 25
    • 0025159174 scopus 로고
    • Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki-67 antigen: a new view of the cell cycle
    • 10.1016/0014-4827(90)90124-S, 1967582.
    • Landberg G, Tan EM, Roos G. Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki-67 antigen: a new view of the cell cycle. Exp Cell Res 1990, 187:111-8. 10.1016/0014-4827(90)90124-S, 1967582.
    • (1990) Exp Cell Res , vol.187 , pp. 111-118
    • Landberg, G.1    Tan, E.M.2    Roos, G.3
  • 26
    • 0032810359 scopus 로고    scopus 로고
    • A quantitative analysis of vascularization and perfusion of human glioma xenografts at different implantation sites
    • 10.1006/mvre.1999.2143, 10329251.
    • Bernsen HJ, Rijken PF, Hagemeier NE, van der Kogel AJ. A quantitative analysis of vascularization and perfusion of human glioma xenografts at different implantation sites. Microvasc Res 1999, 57:244-57. 10.1006/mvre.1999.2143, 10329251.
    • (1999) Microvasc Res , vol.57 , pp. 244-257
    • Bernsen, H.J.1    Rijken, P.F.2    Hagemeier, N.E.3    van der Kogel, A.J.4
  • 30
    • 12344312042 scopus 로고    scopus 로고
    • Cellular abnormalities of blood vessels as targets in cancer
    • 10.1016/j.gde.2004.12.005, 15661540.
    • Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005, 15:102-11. 10.1016/j.gde.2004.12.005, 15661540.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 102-111
    • Baluk, P.1    Hashizume, H.2    McDonald, D.M.3
  • 31
    • 33645556386 scopus 로고    scopus 로고
    • NG2 glial cells provide a favorable substrate for growing axons
    • 10.1523/JNEUROSCI.4247-05.2006, 16597737.
    • Yang Z, Suzuki R, Daniels SB, Brunquell CB, Sala CJ, Nishiyama A. NG2 glial cells provide a favorable substrate for growing axons. J Neurosci 2006, 26:3829-39. 10.1523/JNEUROSCI.4247-05.2006, 16597737.
    • (2006) J Neurosci , vol.26 , pp. 3829-3839
    • Yang, Z.1    Suzuki, R.2    Daniels, S.B.3    Brunquell, C.B.4    Sala, C.J.5    Nishiyama, A.6
  • 33
    • 0036897097 scopus 로고    scopus 로고
    • Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs
    • Bocci G, Nicolaou KC, Kerbel RS. Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Res 2002, 62:6938-43.
    • (2002) Cancer Res , vol.62 , pp. 6938-6943
    • Bocci, G.1    Nicolaou, K.C.2    Kerbel, R.S.3
  • 34
    • 60749108001 scopus 로고    scopus 로고
    • Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
    • 10.1016/j.ejpb.2008.11.010, 19070661.
    • Maeda H, Bharate GY, Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur J Pharm Biopharm 2009, 71:409-19. 10.1016/j.ejpb.2008.11.010, 19070661.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 409-419
    • Maeda, H.1    Bharate, G.Y.2    Daruwalla, J.3
  • 35
    • 33846478656 scopus 로고    scopus 로고
    • DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents
    • 2359994, 17211479.
    • O'Connor JP, Jackson A, Parker GJ, Jayson GC. DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents. Br J Cancer 2007, 96:189-95. 2359994, 17211479.
    • (2007) Br J Cancer , vol.96 , pp. 189-195
    • O'Connor, J.P.1    Jackson, A.2    Parker, G.J.3    Jayson, G.C.4
  • 36
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
    • 10.1126/science.1104819, 15637262.
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005, 307:58-62. 10.1126/science.1104819, 15637262.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 37
    • 0015139261 scopus 로고
    • Vascular changes in tumours after treatment with ICRF 159
    • 1665898, 5158233.
    • Le Serve AW, Hellmann K. Vascular changes in tumours after treatment with ICRF 159. Br J Pharmacol 1971, 43:457P-458P. 1665898, 5158233.
    • (1971) Br J Pharmacol , vol.43
    • Le Serve, A.W.1    Hellmann, K.2
  • 38
    • 2342422295 scopus 로고    scopus 로고
    • Vascular microenvironment in gliomas
    • Vajkoczy P, Menger MD. Vascular microenvironment in gliomas. Cancer Treat Res 2004, 117:249-62.
    • (2004) Cancer Treat Res , vol.117 , pp. 249-262
    • Vajkoczy, P.1    Menger, M.D.2
  • 39
    • 0019363468 scopus 로고
    • The vasculature of experimental brain tumours. Part 1. A sequential light and electron microscope study of angiogenesis
    • 10.1016/0022-510X(81)90188-X, 7205320.
    • Deane BR, Lantos PL. The vasculature of experimental brain tumours. Part 1. A sequential light and electron microscope study of angiogenesis. J Neurol Sci 1981, 49:55-66. 10.1016/0022-510X(81)90188-X, 7205320.
    • (1981) J Neurol Sci , vol.49 , pp. 55-66
    • Deane, B.R.1    Lantos, P.L.2
  • 41
    • 0038476590 scopus 로고    scopus 로고
    • Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models
    • 10.1124/jpet.102.048587, 12626639.
    • Ma J, Li S, Reed K, Guo P, Gallo JM. Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models. J Pharmacol Exp Ther 2003, 305:833-9. 10.1124/jpet.102.048587, 12626639.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 833-839
    • Ma, J.1    Li, S.2    Reed, K.3    Guo, P.4    Gallo, J.M.5
  • 42
    • 0030822996 scopus 로고    scopus 로고
    • P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer
    • 10.1111/j.1432-1033.1997.00115.x, 9431998.
    • Shapiro AB, Corder AB, Ling V. P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer. Eur J Biochem 1997, 250:115-21. 10.1111/j.1432-1033.1997.00115.x, 9431998.
    • (1997) Eur J Biochem , vol.250 , pp. 115-121
    • Shapiro, A.B.1    Corder, A.B.2    Ling, V.3
  • 43
    • 0034048358 scopus 로고    scopus 로고
    • Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
    • 10.1172/JCI9872, 300842, 10772648.
    • Hanahan D, Bergers G, Bergsland E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J Clin Invest 2000, 105:1045-7. 10.1172/JCI9872, 300842, 10772648.
    • (2000) J Clin Invest , vol.105 , pp. 1045-1047
    • Hanahan, D.1    Bergers, G.2    Bergsland, E.3
  • 47
    • 0030863434 scopus 로고    scopus 로고
    • Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions
    • Slatter JG, Su P, Sams JP, Schaaf LJ, Wienkers LC. Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions. Drug Metab Dispos 1997, 25:1157-64.
    • (1997) Drug Metab Dispos , vol.25 , pp. 1157-1164
    • Slatter, J.G.1    Su, P.2    Sams, J.P.3    Schaaf, L.J.4    Wienkers, L.C.5
  • 49
    • 34249981734 scopus 로고    scopus 로고
    • Cisplatin and doxorubicin repress Vascular Endothelial Growth Factor expression and differentially down-regulate Hypoxia-inducible Factor I activity in human ovarian cancer cells
    • 10.1016/j.bcp.2007.04.003, 17498666.
    • Duyndam MC, van Berkel MP, Dorsman JC, Rockx DA, Pinedo HM, Boven E. Cisplatin and doxorubicin repress Vascular Endothelial Growth Factor expression and differentially down-regulate Hypoxia-inducible Factor I activity in human ovarian cancer cells. Biochem Pharmacol 2007, 74:191-201. 10.1016/j.bcp.2007.04.003, 17498666.
    • (2007) Biochem Pharmacol , vol.74 , pp. 191-201
    • Duyndam, M.C.1    van Berkel, M.P.2    Dorsman, J.C.3    Rockx, D.A.4    Pinedo, H.M.5    Boven, E.6
  • 50
    • 0025360799 scopus 로고
    • Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine
    • 10.3171/jns.1990.73.2.0254, 2366082.
    • Asai A, Shibui S, Barker M, Vanderlaan M, Gray JW, Hoshino T. Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine. J Neurosurg 1990, 73:254-8. 10.3171/jns.1990.73.2.0254, 2366082.
    • (1990) J Neurosurg , vol.73 , pp. 254-258
    • Asai, A.1    Shibui, S.2    Barker, M.3    Vanderlaan, M.4    Gray, J.W.5    Hoshino, T.6
  • 51
    • 78650138276 scopus 로고    scopus 로고
    • Influence of blood-brain barrier efflux pumps on the distribution of vincristine in brain and brain tumors
    • 10.1093/neuonc/noq056, 20501632.
    • Wang F, Zhou F, Kruh GD, Gallo JM. Influence of blood-brain barrier efflux pumps on the distribution of vincristine in brain and brain tumors. Neuro Oncol 2010, 12:1043-9. 10.1093/neuonc/noq056, 20501632.
    • (2010) Neuro Oncol , vol.12 , pp. 1043-1049
    • Wang, F.1    Zhou, F.2    Kruh, G.D.3    Gallo, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.