Extracellular IgC2 constant domains of CEACAMs mediate PI3K sensitivity during uptake of pathogens

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Voges, Maike ^a   Bachmann, Verena ^a,b   Naujoks, Jan ^a,c   Kopp, Kathrin ^a   Hauck, Christof R ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b UNIVERSITY OF ALBERTA   (Canada)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 3; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 6; CHOLESTEROL; IMMUNOGLOBULIN; IMMUNOGLOBULIN C2 CONSTANT DOMAIN; LYMPHOCYTE ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN SHIP; UNCLASSIFIED DRUG; CD66 ANTIGENS; CELL ADHESION MOLECULE; INOSITOL 1,4,5 TRISPHOSPHATE 5 PHOSPHATASE; INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE; LEUKOCYTE ANTIGEN; MUTANT PROTEIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POLYPHOSPHOINOSITIDE; RECOMBINANT PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; BACTERIUM ADHERENCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENDOCYTOSIS; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; INTERNALIZATION; NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS; NONHUMAN; PHAGOCYTOSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN TRANSPORT; RECEPTOR OCCUPANCY; CELL LINE; CELL MEMBRANE; CHEMISTRY; DRUG ANTAGONISM; EXTRACELLULAR SPACE; IMMUNOGLOBULIN CONSTANT REGION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS;

ANTIGENS, CD; BACTERIAL ADHESION; CELL ADHESION MOLECULES; CELL LINE; ENDOCYTOSIS; ENDOTHELIAL CELLS; EXTRACELLULAR SPACE; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; MEMBRANE MICRODOMAINS; MUTANT PROTEINS; NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84863098023     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039908     Document Type: Article

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