A role for phosphoinositide 3-kinase in bacterial invasion

Science

Volumn 274, Issue 5288, 1996, Pages 780-782

  Ireton, Keith ^a   Payrastre, Bernard ^b   Chap, Hugues ^b   Ogawa, Wataru ^c   Sakaue, Hiroshi ^c   Kasuga, Masato ^c   Cossart, Pascale ^a  

^a INSTITUT PASTEUR   (France)

^b CHU PURPAN   (France)

^c KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; BACTERIAL PROTEIN; DYNAMIN; PHOSPHATIDYLINOSITIDE; PHOSPHOTRANSFERASE; TYROSINE DERIVATIVE;

ACTIN POLYMERIZATION; ARTICLE; BACTERIAL INFECTION; CELL INVASION; ENDOCYTOSIS; ENZYME ACTIVITY; LISTERIA MONOCYTOGENES; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; BACTERIAL PROTEINS; CELL LINE; CHROMONES; CYTOCHALASIN D; ENZYME ACTIVATION; ENZYME INHIBITORS; GENISTEIN; HUMANS; ISOFLAVONES; LISTERIA MONOCYTOGENES; MEMBRANE PROTEINS; MORPHOLINES; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PHOSPHOTYROSINE; TUMOR CELLS, CULTURED;

BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES;

EID: 0029958304     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5288.780     Document Type: Article

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23. Supported by grants from the Ministere de l'Agriculture et la Peche (R94-35), DRET (93-109), INSERM (CRE93013), the Ministere de la Recherche (ACCSV6), and the Pasteur Institute. K.I. is a recipient of a fellowship from the Jane Coffin Childs Memorial Fund for Medical Research. We thank P. Boquet for suggesting wortmannin, and Jerôme Mengaud for critically reading the manuscript.