Twenty-six-week oral toxicity of diheptyl phthalate with special emphasis on its induction of liver proliferative lesions in male F344 rats

Journal of Toxicological Sciences

Volumn 37, Issue 3, 2012, Pages 527-537

  Nakane, Fumiyuki ^a   Kunieda, Masaki ^a   Shimiz, Shigekazu ^a   Kobayashi, Yoshihiko ^a   Akane, Hirotoshi ^a   Akie, Yasuki ^a   Saito, Akemi ^a   Noguchi, Masayoshi ^a   Kadota, Toshihito ^a   Mitsumori, Kunitoshi ^b  

^a Musashi Energy Solutions Co   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

26 week toxicity; Diheptyl phthalate; Phthalate esters; PPAR agonist; Preneoplastic foci

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; CYCLINE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; GLUTATHIONE TRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PHOSPHOLIPID; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DIHEPTYL ESTER; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN DETECTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BASOPHIL; CELL COUNT; CELL INCLUSION; CELL PROLIFERATION; CELL VACUOLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; EOSINOPHIL; FLUID INTAKE; FOOD INTAKE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; LIVER CELL; LIVER CELL DAMAGE; LIVER HYPERTROPHY; MALE; NONHUMAN; ORGAN WEIGHT; PHOSPHOLIPID BLOOD LEVEL; PROSTATE; PROTEIN BLOOD LEVEL; RAT; TESTIS; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

PUNCTUM BLANDIANUM; RATTUS;

EID: 84863085953     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.37.527     Document Type: Article

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