Synthesis and evaluation of 18F-labeled styryltriazole and resveratrol derivatives for β-amyloid plaque imaging

Journal of Medicinal Chemistry

Volumn 55, Issue 2, 2012, Pages 883-892

  Lee, Iljung ^a   Choe, Yearn Seong ^a   Choi, Joon Young ^a   Lee, Kyung Han ^a   Kim, Byung Tae ^a  

^a Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 FLUOROETHYL) 4 (4 N,N DIMETHYLAMINOSTYRYL) 1H 1,2,3 TRIAZOLE F 18; 1 (4 FLUOROSTYRYL) 3,5 DIMETHOXYBENZENE F 18; 1 [4 (2 FLUOROETHOXY)STYRYL] 3,5 DIMETHOXYBENZENE; 1 [4 (3 FLUOROPROPOXY)STYRYL] 3,5 DIMETHOXYBENZENE; 5 (4 FLUOROSTYRYL)BENZENE 1,3 DIOL F 18; AMYLOID BETA PROTEIN[1-42]; RADIOPHARMACEUTICAL AGENT; RESVERATROL; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 1 (2 FLUOROETHYL) 4 (4 N,N DIMETHYLAMINOSTYRYL) 1H 1,2,3 TRIAZOLE; 1 (4 (3 FLUOROPROPOXY)STYRYL) 3,5 DIMETHOXYBENZENE; 1-(2-FLUOROETHYL)-4-(4-N,N-DIMETHYLAMINOSTYRYL)-1H-1,2,3-TRIAZOLE; 1-(4-(3-FLUOROPROPOXY)STYRYL)-3,5-DIMETHOXYBENZENE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); ANILINE DERIVATIVE; FLUORINE; PEPTIDE FRAGMENT; STILBENE DERIVATIVE; STYRENE DERIVATIVE;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEFLUORINATION; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG SYNTHESIS; DRUG UPTAKE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PROTEIN AGGREGATION; TISSUE DISTRIBUTION; ANIMAL; BRAIN; CHEMISTRY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; RADIOASSAY; SCINTISCANNING; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMYLOID BETA-PEPTIDES; ANILINE COMPOUNDS; ANIMALS; BRAIN; FLUORINE RADIOISOTOPES; MALE; MICE; MICE, INBRED ICR; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; STEREOISOMERISM; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; STYRENES; TISSUE DISTRIBUTION; TRIAZOLES;

EID: 84863077449     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201400q     Document Type: Article

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