메뉴 건너뛰기




Volumn 13, Issue 1, 2012, Pages 1209-1224

Targeting protective autophagy exacerbates UV-triggered apoptotic cell death

Author keywords

Apoptosis; Autophagy; UV

Indexed keywords

ATR PROTEIN; AUTOPHAGY PROTEIN 5; BECLIN 1; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3B II; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; ATG5 PROTEIN, HUMAN; ATM PROTEIN; ATR PROTEIN, HUMAN; BECN1 PROTEIN, HUMAN; MAP1LC3A PROTEIN, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; SMALL INTERFERING RNA;

EID: 84863066448     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13011209     Document Type: Article
Times cited : (37)

References (33)
  • 2
    • 42149086603 scopus 로고    scopus 로고
    • Cisplatin treatment of NIH/3T3 cultures induces a form of autophagic death in polyploid cells
    • Spano, A.; Monaco, G.; Barni, S.; Sciola, L. Cisplatin treatment of NIH/3T3 cultures induces a form of autophagic death in polyploid cells. Histol. Histopathol. 2008, 23, 717-730.
    • (2008) Histol. Histopathol. , vol.23 , pp. 717-730
    • Spano, A.1    Monaco, G.2    Barni, S.3    Sciola, L.4
  • 3
    • 49749120592 scopus 로고    scopus 로고
    • Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
    • Periyasamy-Thandavan, S.; Jiang, M.; Wei, Q.; Smith, R.; Yin, X.M.; Dong, Z. Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells. Kidney Int. 2008, 74, 631-640.
    • (2008) Kidney Int , vol.74 , pp. 631-640
    • Periyasamy-Thandavan, S.1    Jiang, M.2    Wei, Q.3    Smith, R.4    Yin, X.M.5    Dong, Z.6
  • 4
    • 33847026354 scopus 로고    scopus 로고
    • Autophagy delays apoptotic death in breast cancer cells following DNA damage
    • Abedin, M.J.; Wang, D.; McDonnell, M.A.; Lehmann, U.; Kelekar, A. Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ. 2007, 14, 500-510.
    • (2007) Cell Death Differ , vol.14 , pp. 500-510
    • Abedin, M.J.1    Wang, D.2    McDonnell, M.A.3    Lehmann, U.4    Kelekar, A.5
  • 5
    • 73149108422 scopus 로고    scopus 로고
    • G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells
    • Zhou, W.J.; Deng, R.; Zhang, X.Y.; Feng, G.K.; Gu, L.Q.; Zhu, X.F. G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells. Mol. Cancer Ther. 2009, 8, 3203-3213.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 3203-3213
    • Zhou, W.J.1    Deng, R.2    Zhang, X.Y.3    Feng, G.K.4    Gu, L.Q.5    Zhu, X.F.6
  • 6
    • 0033520432 scopus 로고    scopus 로고
    • Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation
    • Suzuki, K.; Kodama, S.; Watanabe, M. Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. J. Biol. Chem. 1999, 274, 25571-25575.
    • (1999) J. Biol. Chem. , vol.274 , pp. 25571-25575
    • Suzuki, K.1    Kodama, S.2    Watanabe, M.3
  • 8
    • 0034102337 scopus 로고    scopus 로고
    • ATR disruption leads to chromosomal fragmentation and early embryonic lethality
    • Brown, E.J.; Baltimore, D. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev. 2000, 14, 397-402.
    • (2000) Genes Dev , vol.14 , pp. 397-402
    • Brown, E.J.1    Baltimore, D.2
  • 9
    • 70349852751 scopus 로고    scopus 로고
    • Mouse models for ATR deficiency
    • O'Driscoll, M. Mouse models for ATR deficiency. DNA Repair (Amst) 2009, 8, 1333-1337.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 1333-1337
    • O'Driscoll, M.1
  • 10
    • 0035941021 scopus 로고    scopus 로고
    • ATR and ATRIP: Partners in checkpoint signaling
    • Cortez, D.; Guntuku, S.; Qin, J.; Elledge, S.J. ATR and ATRIP: Partners in checkpoint signaling. Science 2001, 294, 1713-1716.
    • (2001) Science , vol.294 , pp. 1713-1716
    • Cortez, D.1    Guntuku, S.2    Qin, J.3    Elledge, S.J.4
  • 13
    • 54349115389 scopus 로고    scopus 로고
    • Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy
    • Rieber, M.; Rieber, M.S. Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy. Cancer Biol. Ther. 2008, 7, 1561-1566.
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1561-1566
    • Rieber, M.1    Rieber, M.S.2
  • 14
    • 79551473364 scopus 로고    scopus 로고
    • Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway
    • Chen, L.H.; Loong, C.C.; Su, T.L.; Lee, Y.J.; Chu, P.M.; Tsai, M.L.; Tsai, P.H.; Tu, P.H.; Chi, C.W.; Lee, H.C; et al. Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway. Biochem. Pharmacol. 2011, 81, 594-605.
    • (2011) Biochem. Pharmacol. , vol.81 , pp. 594-605
    • Chen, L.H.1    Loong, C.C.2    Su, T.L.3    Lee, Y.J.4    Chu, P.M.5    Tsai, M.L.6    Tsai, P.H.7    Tu, P.H.8    Chi, C.W.9    Lee, H.C.10
  • 17
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri, M.C.; Zalckvar, E.; Kimchi, A.; Kroemer, G. Self-eating and self-killing: Crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 2007, 8, 741-752.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 18
    • 33747884339 scopus 로고    scopus 로고
    • DNA damage-induced cell death by apoptosis
    • Roos, W.P.; Kaina, B. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 2006, 12, 440-450.
    • (2006) Trends Mol. Med. , vol.12 , pp. 440-450
    • Roos, W.P.1    Kaina, B.2
  • 21
  • 22
    • 67449110953 scopus 로고    scopus 로고
    • ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: Potential basis for the UV protective effects of caffeine
    • Heffernan, T.P.; Kawasumi, M.; Blasina, A.; Anderes, K.; Conney, A.H.; Nghiem, P. ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: Potential basis for the UV protective effects of caffeine. J. Invest. Dermatol. 2009, 129, 1805-1815.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1805-1815
    • Heffernan, T.P.1    Kawasumi, M.2    Blasina, A.3    Anderes, K.4    Conney, A.H.5    Nghiem, P.6
  • 24
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • Yue, Z.; Jin, S.; Yang, C.; Levine, A.J.; Heintz, N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci. USA 2003, 100, 15077-15082.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3    Levine, A.J.4    Heintz, N.5
  • 26
    • 43949141438 scopus 로고    scopus 로고
    • Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy
    • Singh, R.; Czaja, M.J. Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy. Autophagy 2008, 4, 516-518.
    • (2008) Autophagy , vol.4 , pp. 516-518
    • Singh, R.1    Czaja, M.J.2
  • 28
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: Their role in cell survival and cell death
    • Codogno, P.; Meijer, A.J. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ. 2005, 12, 1509-1518.
    • (2005) Cell Death Differ , vol.12 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 29
    • 0035253615 scopus 로고    scopus 로고
    • ATM and ATR: Networking cellular responses to DNA damage
    • Shiloh, Y. ATM and ATR: Networking cellular responses to DNA damage. Curr. Opin. Genet. Dev. 2001, 11, 71-77.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 71-77
    • Shiloh, Y.1
  • 30
    • 12544250589 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage
    • Helt, C.E.; Cliby, W.A.; Keng, P.C.; Bambara, R.A.; O'Reilly, M.A. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage. J. Biol. Chem. 2005, 280, 1186-1192.
    • (2005) J. Biol. Chem. , vol.280 , pp. 1186-1192
    • Helt, C.E.1    Cliby, W.A.2    Keng, P.C.3    Bambara, R.A.4    O'Reilly, M.A.5
  • 33
    • 33646795891 scopus 로고    scopus 로고
    • Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex
    • Adams, K.E.; Medhurst, A.L.; Dart, D.A.; Lakin, N.D. Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex. Oncogene 2006, 25, 3894-3904.
    • (2006) Oncogene , vol.25 , pp. 3894-3904
    • Adams, K.E.1    Medhurst, A.L.2    Dart, D.A.3    Lakin, N.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.