-
1
-
-
42049089700
-
To die or not to die: That is the autophagic question
-
Galluzzi, L.; Vicencio, J.M.; Kepp, O.; Tasdemir, E.; Maiuri, M.C.; Kroemer, G. To die or not to die: That is the autophagic question. Curr. Mol. Med. 2008, 8, 78-91.
-
(2008)
Curr. Mol. Med.
, vol.8
, pp. 78-91
-
-
Galluzzi, L.1
Vicencio, J.M.2
Kepp, O.3
Tasdemir, E.4
Maiuri, M.C.5
Kroemer, G.6
-
2
-
-
42149086603
-
Cisplatin treatment of NIH/3T3 cultures induces a form of autophagic death in polyploid cells
-
Spano, A.; Monaco, G.; Barni, S.; Sciola, L. Cisplatin treatment of NIH/3T3 cultures induces a form of autophagic death in polyploid cells. Histol. Histopathol. 2008, 23, 717-730.
-
(2008)
Histol. Histopathol.
, vol.23
, pp. 717-730
-
-
Spano, A.1
Monaco, G.2
Barni, S.3
Sciola, L.4
-
3
-
-
49749120592
-
Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
-
Periyasamy-Thandavan, S.; Jiang, M.; Wei, Q.; Smith, R.; Yin, X.M.; Dong, Z. Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells. Kidney Int. 2008, 74, 631-640.
-
(2008)
Kidney Int
, vol.74
, pp. 631-640
-
-
Periyasamy-Thandavan, S.1
Jiang, M.2
Wei, Q.3
Smith, R.4
Yin, X.M.5
Dong, Z.6
-
4
-
-
33847026354
-
Autophagy delays apoptotic death in breast cancer cells following DNA damage
-
Abedin, M.J.; Wang, D.; McDonnell, M.A.; Lehmann, U.; Kelekar, A. Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ. 2007, 14, 500-510.
-
(2007)
Cell Death Differ
, vol.14
, pp. 500-510
-
-
Abedin, M.J.1
Wang, D.2
McDonnell, M.A.3
Lehmann, U.4
Kelekar, A.5
-
5
-
-
73149108422
-
G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells
-
Zhou, W.J.; Deng, R.; Zhang, X.Y.; Feng, G.K.; Gu, L.Q.; Zhu, X.F. G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells. Mol. Cancer Ther. 2009, 8, 3203-3213.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 3203-3213
-
-
Zhou, W.J.1
Deng, R.2
Zhang, X.Y.3
Feng, G.K.4
Gu, L.Q.5
Zhu, X.F.6
-
6
-
-
0033520432
-
Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation
-
Suzuki, K.; Kodama, S.; Watanabe, M. Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. J. Biol. Chem. 1999, 274, 25571-25575.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25571-25575
-
-
Suzuki, K.1
Kodama, S.2
Watanabe, M.3
-
8
-
-
0034102337
-
ATR disruption leads to chromosomal fragmentation and early embryonic lethality
-
Brown, E.J.; Baltimore, D. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev. 2000, 14, 397-402.
-
(2000)
Genes Dev
, vol.14
, pp. 397-402
-
-
Brown, E.J.1
Baltimore, D.2
-
9
-
-
70349852751
-
Mouse models for ATR deficiency
-
O'Driscoll, M. Mouse models for ATR deficiency. DNA Repair (Amst) 2009, 8, 1333-1337.
-
(2009)
DNA Repair (Amst)
, vol.8
, pp. 1333-1337
-
-
O'Driscoll, M.1
-
10
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
Cortez, D.; Guntuku, S.; Qin, J.; Elledge, S.J. ATR and ATRIP: Partners in checkpoint signaling. Science 2001, 294, 1713-1716.
-
(2001)
Science
, vol.294
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
11
-
-
0037076402
-
Preferential binding of ATR protein to UV-damaged DNA
-
Unsal-Kacmaz, K.; Makhov, A.M.; Griffith, J.D.; Sancar, A. Preferential binding of ATR protein to UV-damaged DNA. Proc. Natl. Acad. Sci. USA 2002, 99, 6673-6678.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6673-6678
-
-
Unsal-Kacmaz, K.1
Makhov, A.M.2
Griffith, J.D.3
Sancar, A.4
-
13
-
-
54349115389
-
Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy
-
Rieber, M.; Rieber, M.S. Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy. Cancer Biol. Ther. 2008, 7, 1561-1566.
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1561-1566
-
-
Rieber, M.1
Rieber, M.S.2
-
14
-
-
79551473364
-
Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway
-
Chen, L.H.; Loong, C.C.; Su, T.L.; Lee, Y.J.; Chu, P.M.; Tsai, M.L.; Tsai, P.H.; Tu, P.H.; Chi, C.W.; Lee, H.C; et al. Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway. Biochem. Pharmacol. 2011, 81, 594-605.
-
(2011)
Biochem. Pharmacol.
, vol.81
, pp. 594-605
-
-
Chen, L.H.1
Loong, C.C.2
Su, T.L.3
Lee, Y.J.4
Chu, P.M.5
Tsai, M.L.6
Tsai, P.H.7
Tu, P.H.8
Chi, C.W.9
Lee, H.C.10
-
15
-
-
77749233738
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
-
Alexander, A.; Cai, S.L.; Kim, J.; Nanez, A.; Sahin, M.; MacLean, K.H.; Inoki, K.; Guan, K.L.; Shen, J.; Person, M.D.; et al. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc. Natl. Acad. Sci. USA 2010, 107, 4153-4158.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 4153-4158
-
-
Alexander, A.1
Cai, S.L.2
Kim, J.3
Nanez, A.4
Sahin, M.5
Maclean, K.H.6
Inoki, K.7
Guan, K.L.8
Shen, J.9
Person, M.D.10
-
16
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky, D.J.; Abeliovich, H.; Agostinis, P.; Agrawal, D.K.; Aliev, G.; Askew, D.S.; Baba, M.; Baehrecke, E.H.; Bahr, B.A.; Ballabio, A. et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008, 4, 151-175.
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
-
17
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
Maiuri, M.C.; Zalckvar, E.; Kimchi, A.; Kroemer, G. Self-eating and self-killing: Crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 2007, 8, 741-752.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
18
-
-
33747884339
-
DNA damage-induced cell death by apoptosis
-
Roos, W.P.; Kaina, B. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 2006, 12, 440-450.
-
(2006)
Trends Mol. Med.
, vol.12
, pp. 440-450
-
-
Roos, W.P.1
Kaina, B.2
-
19
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang, X.H.; Jackson, S.; Seaman, M.; Brown, K.; Kempkes, B.; Hibshoosh, H.; Levine, B. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999, 402, 672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
20
-
-
0035911162
-
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
-
Mizushima, N.; Yamamoto, A.; Hatano, M.; Kobayashi, Y.; Kabeya, Y.; Suzuki, K.; Tokuhisa, T.; Ohsumi, Y.; Yoshimori, T. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J. Cell Biol. 2001, 152, 657-668.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 657-668
-
-
Mizushima, N.1
Yamamoto, A.2
Hatano, M.3
Kobayashi, Y.4
Kabeya, Y.5
Suzuki, K.6
Tokuhisa, T.7
Ohsumi, Y.8
Yoshimori, T.9
-
22
-
-
67449110953
-
ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: Potential basis for the UV protective effects of caffeine
-
Heffernan, T.P.; Kawasumi, M.; Blasina, A.; Anderes, K.; Conney, A.H.; Nghiem, P. ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: Potential basis for the UV protective effects of caffeine. J. Invest. Dermatol. 2009, 129, 1805-1815.
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 1805-1815
-
-
Heffernan, T.P.1
Kawasumi, M.2
Blasina, A.3
Anderes, K.4
Conney, A.H.5
Nghiem, P.6
-
23
-
-
53849101410
-
Life, death and burial: Multifaceted impact of autophagy
-
Galluzzi, L.; Morselli, E.; Vicencio, J.M.; Kepp, O.; Joza, N.; Tajeddine, N.; Kroemer, G. Life, death and burial: Multifaceted impact of autophagy. Biochem. Soc. Trans. 2008, 36, 786-790.
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 786-790
-
-
Galluzzi, L.1
Morselli, E.2
Vicencio, J.M.3
Kepp, O.4
Joza, N.5
Tajeddine, N.6
Kroemer, G.7
-
24
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue, Z.; Jin, S.; Yang, C.; Levine, A.J.; Heintz, N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci. USA 2003, 100, 15077-15082.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
25
-
-
41949125675
-
Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus
-
Wang, Y.; Singh, R.; Massey, A.C.; Kane, S.S.; Kaushik, S.; Grant, T.; Xiang, Y.; Cuervo, A.M.; Czaja, M.J. Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus. J. Biol. Chem. 2008, 283, 4766-4777.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4766-4777
-
-
Wang, Y.1
Singh, R.2
Massey, A.C.3
Kane, S.S.4
Kaushik, S.5
Grant, T.6
Xiang, Y.7
Cuervo, A.M.8
Czaja, M.J.9
-
26
-
-
43949141438
-
Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy
-
Singh, R.; Czaja, M.J. Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy. Autophagy 2008, 4, 516-518.
-
(2008)
Autophagy
, vol.4
, pp. 516-518
-
-
Singh, R.1
Czaja, M.J.2
-
27
-
-
33750596317
-
Differential mechanisms of conjunctival cell death induction by ultraviolet irradiation and benzalkonium chloride
-
Buron, N.; Micheau, O.; Cathelin, S.; Lafontaine, P.O.; Creuzot-Garcher, C.; Solary, E. Differential mechanisms of conjunctival cell death induction by ultraviolet irradiation and benzalkonium chloride. Invest. Ophthalmol. Vis. Sci. 2006, 47, 4221-4230.
-
(2006)
Invest. Ophthalmol. Vis. Sci.
, vol.47
, pp. 4221-4230
-
-
Buron, N.1
Micheau, O.2
Cathelin, S.3
Lafontaine, P.O.4
Creuzot-Garcher, C.5
Solary, E.6
-
28
-
-
27644466759
-
Autophagy and signaling: Their role in cell survival and cell death
-
Codogno, P.; Meijer, A.J. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ. 2005, 12, 1509-1518.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1509-1518
-
-
Codogno, P.1
Meijer, A.J.2
-
29
-
-
0035253615
-
ATM and ATR: Networking cellular responses to DNA damage
-
Shiloh, Y. ATM and ATR: Networking cellular responses to DNA damage. Curr. Opin. Genet. Dev. 2001, 11, 71-77.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 71-77
-
-
Shiloh, Y.1
-
30
-
-
12544250589
-
Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage
-
Helt, C.E.; Cliby, W.A.; Keng, P.C.; Bambara, R.A.; O'Reilly, M.A. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage. J. Biol. Chem. 2005, 280, 1186-1192.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1186-1192
-
-
Helt, C.E.1
Cliby, W.A.2
Keng, P.C.3
Bambara, R.A.4
O'Reilly, M.A.5
-
31
-
-
33845715977
-
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
-
Stiff, T.; Walker, S.A.; Cerosaletti, K.; Goodarzi, A.A.; Petermann, E.; Concannon, P.; O'Driscoll M.; Jeggo, P.A. ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. EMBO J. 2006, 25, 5775-5782.
-
(2006)
EMBO J
, vol.25
, pp. 5775-5782
-
-
Stiff, T.1
Walker, S.A.2
Cerosaletti, K.3
Goodarzi, A.A.4
Petermann, E.5
Concannon, P.6
O'Driscoll, M.7
Jeggo, P.A.8
-
32
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri, A.; Falck, J.; Lukas, C.; Bartek, J.; Smith, G.C.; Lukas, J.; Jackson, S.P. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat. Cell Biol. 2006, 8, 37-45.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.5
Lukas, J.6
Jackson, S.P.7
-
33
-
-
33646795891
-
Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex
-
Adams, K.E.; Medhurst, A.L.; Dart, D.A.; Lakin, N.D. Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex. Oncogene 2006, 25, 3894-3904.
-
(2006)
Oncogene
, vol.25
, pp. 3894-3904
-
-
Adams, K.E.1
Medhurst, A.L.2
Dart, D.A.3
Lakin, N.D.4
|