메뉴 건너뛰기




Volumn 7, Issue 2, 2012, Pages

Ameliorated cona-induced hepatitis in the absence of PKC-theta

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CD40 LIGAND; CONCANAVALIN A; FAS LIGAND; GAMMA INTERFERON; INTERLEUKIN 6; PROTEIN KINASE C THETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; ISOENZYME; PRKCQ PROTEIN, MOUSE; PROTEIN KINASE C;

EID: 84863040855     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031174     Document Type: Article
Times cited : (24)

References (47)
  • 1
    • 0033149863 scopus 로고    scopus 로고
    • Pathogenesis of autoimmune hepatitis
    • McFarlane IG, (1999) Pathogenesis of autoimmune hepatitis. Biomed Pharmacother 53: 255-263.
    • (1999) Biomed Pharmacother , vol.53 , pp. 255-263
    • McFarlane, I.G.1
  • 2
    • 0037967918 scopus 로고    scopus 로고
    • Liver NKT cells: an account of heterogeneity
    • Emoto M, Kaufmann SH, (2003) Liver NKT cells: an account of heterogeneity. Trends Immunol 24: 364-369.
    • (2003) Trends Immunol , vol.24 , pp. 364-369
    • Emoto, M.1    Kaufmann, S.H.2
  • 3
    • 0034058378 scopus 로고    scopus 로고
    • Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18
    • Faggioni R, Jones-Carson J, Reed DA, Dinarello CA, Feingold KR, et al. (2000) Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18. Proc Natl Acad Sci U S A 97: 2367-2372.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2367-2372
    • Faggioni, R.1    Jones-Carson, J.2    Reed, D.A.3    Dinarello, C.A.4    Feingold, K.R.5
  • 4
    • 0028795171 scopus 로고
    • Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor
    • Gantner F, Leist M, Lohse AW, Germann PG, Tiegs G, (1995) Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 21: 190-198.
    • (1995) Hepatology , vol.21 , pp. 190-198
    • Gantner, F.1    Leist, M.2    Lohse, A.W.3    Germann, P.G.4    Tiegs, G.5
  • 5
    • 0028999453 scopus 로고
    • Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models
    • Leist M, Gantner F, Bohlinger I, Tiegs G, Germann PG, et al. (1995) Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol 146: 1220-1234.
    • (1995) Am J Pathol , vol.146 , pp. 1220-1234
    • Leist, M.1    Gantner, F.2    Bohlinger, I.3    Tiegs, G.4    Germann, P.G.5
  • 6
    • 0035424975 scopus 로고    scopus 로고
    • CD1-specific T cells in microbial immunity
    • Gumperz JE, Brenner MB, (2001) CD1-specific T cells in microbial immunity. Curr Opin Immunol 13: 471-478.
    • (2001) Curr Opin Immunol , vol.13 , pp. 471-478
    • Gumperz, J.E.1    Brenner, M.B.2
  • 8
    • 0032587098 scopus 로고    scopus 로고
    • The roles of intrahepatic Valpha14(+) NK1.1(+) T cells for liver injury induced by Salmonella infection in mice
    • Ishigami M, Nishimura H, Naiki Y, Yoshioka K, Kawano T, et al. (1999) The roles of intrahepatic Valpha14(+) NK1.1(+) T cells for liver injury induced by Salmonella infection in mice. Hepatology 29: 1799-1808.
    • (1999) Hepatology , vol.29 , pp. 1799-1808
    • Ishigami, M.1    Nishimura, H.2    Naiki, Y.3    Yoshioka, K.4    Kawano, T.5
  • 9
    • 0034598156 scopus 로고    scopus 로고
    • Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis
    • Kaneko Y, Harada M, Kawano T, Yamashita M, Shibata Y, et al. (2000) Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis. J Exp Med 191: 105-114.
    • (2000) J Exp Med , vol.191 , pp. 105-114
    • Kaneko, Y.1    Harada, M.2    Kawano, T.3    Yamashita, M.4    Shibata, Y.5
  • 10
    • 0033869941 scopus 로고    scopus 로고
    • Regulation of liver inflammatory injury by signal transducer and activator of transcription-6
    • Kato A, Yoshidome H, Edwards MJ, Lentsch AB, (2000) Regulation of liver inflammatory injury by signal transducer and activator of transcription-6. Am J Pathol 157: 297-302.
    • (2000) Am J Pathol , vol.157 , pp. 297-302
    • Kato, A.1    Yoshidome, H.2    Edwards, M.J.3    Lentsch, A.B.4
  • 11
    • 0032698211 scopus 로고    scopus 로고
    • Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells
    • Kawano T, Nakayama T, Kamada N, Kaneko Y, Harada M, et al. (1999) Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells. Cancer Res 59: 5102-5105.
    • (1999) Cancer Res , vol.59 , pp. 5102-5105
    • Kawano, T.1    Nakayama, T.2    Kamada, N.3    Kaneko, Y.4    Harada, M.5
  • 12
    • 0036838607 scopus 로고    scopus 로고
    • Distinct subsets of human Valpha24-invariant NKT cells: cytokine responses and chemokine receptor expression
    • Kim CH, Butcher EC, Johnston B, (2002) Distinct subsets of human Valpha24-invariant NKT cells: cytokine responses and chemokine receptor expression. Trends Immunol 23: 516-519.
    • (2002) Trends Immunol , vol.23 , pp. 516-519
    • Kim, C.H.1    Butcher, E.C.2    Johnston, B.3
  • 13
    • 0026643743 scopus 로고
    • A T cell-dependent experimental liver injury in mice inducible by concanavalin A
    • Tiegs G, Hentschel J, Wendel A, (1992) A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest 90: 196-203.
    • (1992) J Clin Invest , vol.90 , pp. 196-203
    • Tiegs, G.1    Hentschel, J.2    Wendel, A.3
  • 14
    • 0028863822 scopus 로고
    • Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes
    • Bendelac A, (1995) Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J Exp Med 182: 2091-2096.
    • (1995) J Exp Med , vol.182 , pp. 2091-2096
    • Bendelac, A.1
  • 16
    • 0141958207 scopus 로고    scopus 로고
    • Glycolipid antigen drives rapid expansion and sustained cytokine production by NK T cells
    • Crowe NY, Uldrich AP, Kyparissoudis K, Hammond KJ, Hayakawa Y, et al. (2003) Glycolipid antigen drives rapid expansion and sustained cytokine production by NK T cells. J Immunol 171: 4020-4027.
    • (2003) J Immunol , vol.171 , pp. 4020-4027
    • Crowe, N.Y.1    Uldrich, A.P.2    Kyparissoudis, K.3    Hammond, K.J.4    Hayakawa, Y.5
  • 17
    • 0038544245 scopus 로고    scopus 로고
    • Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development
    • Sivakumar V, Hammond KJ, Howells N, Pfeffer K, Weih F, (2003) Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development. J Exp Med 197: 1613-1621.
    • (2003) J Exp Med , vol.197 , pp. 1613-1621
    • Sivakumar, V.1    Hammond, K.J.2    Howells, N.3    Pfeffer, K.4    Weih, F.5
  • 18
    • 0033625869 scopus 로고    scopus 로고
    • Protein kinase Ctheta: a new essential superstar on the T-cell stage
    • Altman A, Isakov N, Baier G, (2000) Protein kinase Ctheta: a new essential superstar on the T-cell stage. Immunol Today 21: 567-573.
    • (2000) Immunol Today , vol.21 , pp. 567-573
    • Altman, A.1    Isakov, N.2    Baier, G.3
  • 19
    • 0038620475 scopus 로고    scopus 로고
    • Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells
    • Pfeifhofer C, Kofler K, Gruber T, Tabrizi NG, Lutz C, et al. (2003) Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells. J Exp Med 197: 1525-1535.
    • (2003) J Exp Med , vol.197 , pp. 1525-1535
    • Pfeifhofer, C.1    Kofler, K.2    Gruber, T.3    Tabrizi, N.G.4    Lutz, C.5
  • 20
    • 18844473151 scopus 로고    scopus 로고
    • PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes
    • Sun Z, Arendt CW, Ellmeier W, Schaeffer EM, Sunshine MJ, et al. (2000) PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature 404: 402-407.
    • (2000) Nature , vol.404 , pp. 402-407
    • Sun, Z.1    Arendt, C.W.2    Ellmeier, W.3    Schaeffer, E.M.4    Sunshine, M.J.5
  • 21
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss A, Littman DR, (1994) Signal transduction by lymphocyte antigen receptors. Cell 76: 263-274.
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 22
    • 0029670089 scopus 로고    scopus 로고
    • Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes
    • Baier-Bitterlich G, Uberall F, Bauer B, Fresser F, Wachter H, et al. (1996) Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes. Mol Cell Biol 16: 1842-1850.
    • (1996) Mol Cell Biol , vol.16 , pp. 1842-1850
    • Baier-Bitterlich, G.1    Uberall, F.2    Bauer, B.3    Fresser, F.4    Wachter, H.5
  • 23
    • 0034724201 scopus 로고    scopus 로고
    • NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta
    • Coudronniere N, Villalba M, Englund N, Altman A, (2000) NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. Proc Natl Acad Sci U S A 97: 3394-3399.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3394-3399
    • Coudronniere, N.1    Villalba, M.2    Englund, N.3    Altman, A.4
  • 24
    • 0034031401 scopus 로고    scopus 로고
    • Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta
    • Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC, (2000) Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. Mol Cell Biol 20: 2933-2940.
    • (2000) Mol Cell Biol , vol.20 , pp. 2933-2940
    • Lin, X.1    O'Mahony, A.2    Mu, Y.3    Geleziunas, R.4    Greene, W.C.5
  • 25
    • 1842524184 scopus 로고    scopus 로고
    • SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway
    • Li Y, Hu J, Vita R, Sun B, Tabata H, et al. (2004) SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway. EMBO J 23: 1112-1122.
    • (2004) EMBO J , vol.23 , pp. 1112-1122
    • Li, Y.1    Hu, J.2    Vita, R.3    Sun, B.4    Tabata, H.5
  • 26
    • 0038701681 scopus 로고    scopus 로고
    • The PKC gene module: molecular biosystematics to resolve its T cell functions
    • Baier G, (2003) The PKC gene module: molecular biosystematics to resolve its T cell functions. Immunol Rev 192: 64-79.
    • (2003) Immunol Rev , vol.192 , pp. 64-79
    • Baier, G.1
  • 27
    • 79954507884 scopus 로고    scopus 로고
    • PKC-theta is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection
    • Kwon MJ, Wang R, Ma J, Sun Z, (2010) PKC-theta is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection. Endocr Metab Immune Disord Drug Targets 10: 367-372.
    • (2010) Endocr Metab Immune Disord Drug Targets , vol.10 , pp. 367-372
    • Kwon, M.J.1    Wang, R.2    Ma, J.3    Sun, Z.4
  • 28
    • 77956310634 scopus 로고    scopus 로고
    • Efficient Isolation of Mouse Liver NKT Cells by Perfusion
    • Fang X, Du P, Liu Y, Tang J, (2010) Efficient Isolation of Mouse Liver NKT Cells by Perfusion. PLoS ONE 5: e10288.
    • (2010) PLoS ONE , vol.5
    • Fang, X.1    Du, P.2    Liu, Y.3    Tang, J.4
  • 29
    • 44449137653 scopus 로고    scopus 로고
    • Assessment of lymphocyte development in radiation bone marrow chimeras
    • Unit 4 6
    • Spangrude GJ, (2008) Assessment of lymphocyte development in radiation bone marrow chimeras. Curr Protoc Immunol Chapter 4: Unit 4 6.
    • (2008) Curr Protoc Immunol Chapter , vol.4
    • Spangrude, G.J.1
  • 31
    • 0033936909 scopus 로고    scopus 로고
    • Essential pathogenetic role for interferon (IFN-)gamma in concanavalin A-induced T cell-dependent hepatitis: exacerbation by exogenous IFN-gamma and prevention by IFN-gamma receptor-immunoglobulin fusion protein
    • Nicoletti F, Zaccone P, Xiang M, Magro G, Di Mauro M, et al. (2000) Essential pathogenetic role for interferon (IFN-)gamma in concanavalin A-induced T cell-dependent hepatitis: exacerbation by exogenous IFN-gamma and prevention by IFN-gamma receptor-immunoglobulin fusion protein. Cytokine 12: 315-323.
    • (2000) Cytokine , vol.12 , pp. 315-323
    • Nicoletti, F.1    Zaccone, P.2    Xiang, M.3    Magro, G.4    Di Mauro, M.5
  • 32
    • 0028025320 scopus 로고
    • Kinetics of tumour necrosis factor-alpha, soluble tumour necrosis factor receptors, interleukin 1-beta and its receptor antagonist during serious infections
    • van Deuren M, (1994) Kinetics of tumour necrosis factor-alpha, soluble tumour necrosis factor receptors, interleukin 1-beta and its receptor antagonist during serious infections. Eur J Clin Microbiol Infect Dis 13 (Suppl 1): S12-16.
    • (1994) Eur J Clin Microbiol Infect Dis , vol.13 , Issue.SUPPL. 1
    • van Deuren, M.1
  • 33
    • 42149085600 scopus 로고    scopus 로고
    • Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer
    • Ramaiah SK, Rittling S, (2008) Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer. Toxicol Sci 103: 4-13.
    • (2008) Toxicol Sci , vol.103 , pp. 4-13
    • Ramaiah, S.K.1    Rittling, S.2
  • 34
    • 51349121407 scopus 로고    scopus 로고
    • The transcription factor PLZF directs the effector program of the NKT cell lineage
    • Savage AK, Constantinides MG, Han J, Picard D, Martin E, et al. (2008) The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 29: 391-403.
    • (2008) Immunity , vol.29 , pp. 391-403
    • Savage, A.K.1    Constantinides, M.G.2    Han, J.3    Picard, D.4    Martin, E.5
  • 35
    • 0346422479 scopus 로고    scopus 로고
    • Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1
    • Higuchi H, Grambihler A, Canbay A, Bronk SF, Gores GJ, (2004) Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J Biol Chem 279: 51-60.
    • (2004) J Biol Chem , vol.279 , pp. 51-60
    • Higuchi, H.1    Grambihler, A.2    Canbay, A.3    Bronk, S.F.4    Gores, G.J.5
  • 36
    • 34547193134 scopus 로고    scopus 로고
    • Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity
    • Malhi H, Barreyro FJ, Isomoto H, Bronk SF, Gores GJ, (2007) Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. Gut 56: 1124-1131.
    • (2007) Gut , vol.56 , pp. 1124-1131
    • Malhi, H.1    Barreyro, F.J.2    Isomoto, H.3    Bronk, S.F.4    Gores, G.J.5
  • 37
    • 7044272844 scopus 로고    scopus 로고
    • To be or not to be NKT: natural killer T cells in the liver
    • Exley MA, Koziel MJ, (2004) To be or not to be NKT: natural killer T cells in the liver. Hepatology 40: 1033-1040.
    • (2004) Hepatology , vol.40 , pp. 1033-1040
    • Exley, M.A.1    Koziel, M.J.2
  • 40
    • 1842424840 scopus 로고    scopus 로고
    • Cutting edge: the ontogeny and function of Va14Ja18 natural T lymphocytes require signal processing by protein kinase C theta and NF-kappa B
    • Stanic AK, Bezbradica JS, Park JJ, Van Kaer L, Boothby MR, et al. (2004) Cutting edge: the ontogeny and function of Va14Ja18 natural T lymphocytes require signal processing by protein kinase C theta and NF-kappa B. J Immunol 172: 4667-4671.
    • (2004) J Immunol , vol.172 , pp. 4667-4671
    • Stanic, A.K.1    Bezbradica, J.S.2    Park, J.J.3    van Kaer, L.4    Boothby, M.R.5
  • 41
    • 1842480966 scopus 로고    scopus 로고
    • Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation
    • Schmidt-Supprian M, Tian J, Grant EP, Pasparakis M, Maehr R, et al. (2004) Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation. Proc Natl Acad Sci U S A 101: 4566-4571.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4566-4571
    • Schmidt-Supprian, M.1    Tian, J.2    Grant, E.P.3    Pasparakis, M.4    Maehr, R.5
  • 42
    • 33947097707 scopus 로고    scopus 로고
    • Selective function of PKC-theta in T cells
    • Manicassamy S, Gupta S, Sun Z, (2006) Selective function of PKC-theta in T cells. Cell Mol Immunol 3: 263-270.
    • (2006) Cell Mol Immunol , vol.3 , pp. 263-270
    • Manicassamy, S.1    Gupta, S.2    Sun, Z.3
  • 43
    • 0031201232 scopus 로고    scopus 로고
    • Requirement of IL-4 and liver NK1+ T cells for concanavalin A-induced hepatic injury in mice
    • Toyabe S, Seki S, Iiai T, Takeda K, Shirai K, et al. (1997) Requirement of IL-4 and liver NK1+ T cells for concanavalin A-induced hepatic injury in mice. J Immunol 159: 1537-1542.
    • (1997) J Immunol , vol.159 , pp. 1537-1542
    • Toyabe, S.1    Seki, S.2    Iiai, T.3    Takeda, K.4    Shirai, K.5
  • 44
    • 5644276291 scopus 로고    scopus 로고
    • Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases
    • Diao H, Kon S, Iwabuchi K, Kimura C, Morimoto J, et al. (2004) Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases. Immunity 21: 539-550.
    • (2004) Immunity , vol.21 , pp. 539-550
    • Diao, H.1    Kon, S.2    Iwabuchi, K.3    Kimura, C.4    Morimoto, J.5
  • 45
    • 33845921462 scopus 로고    scopus 로고
    • The critical role of protein kinase C-theta in Fas/Fas ligand-mediated apoptosis
    • Manicassamy S, Sun Z, (2007) The critical role of protein kinase C-theta in Fas/Fas ligand-mediated apoptosis. J Immunol 178: 312-319.
    • (2007) J Immunol , vol.178 , pp. 312-319
    • Manicassamy, S.1    Sun, Z.2
  • 47
    • 0036322130 scopus 로고    scopus 로고
    • Diagnosis and treatment of autoimmune hepatitis
    • Czaja AJ, Freese DK, (2002) Diagnosis and treatment of autoimmune hepatitis. Hepatology 36: 479-497.
    • (2002) Hepatology , vol.36 , pp. 479-497
    • Czaja, A.J.1    Freese, D.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.