Marine fungal metabolite 1386A alters the microRNA profile in MCF-7 breast cancer cells

Molecular Medicine Reports

Volumn 5, Issue 3, 2012, Pages 610-618

  Tang, Bing ^a   He, Wei Ling ^a   Zheng, Cheng ^b   Cheang, Tuck Yun ^a   Zhang, X I Fang ^c   Wu, Hui ^a   Yang, Hui Ling ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Zhaoqing No 1 People's Hospital   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Anticancer drug pharmacology; Antineoplastic agents; Breast cancer; Gene expression regulation; TGF

Indexed keywords

ANTINEOPLASTIC AGENT; MARINE FUNGAL METABOLITE 1386A; MICRORNA; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; FUNGAL METABOLISM; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IC 50; MARINE SPECIES; METABOLITE; METASTASIS; MICROARRAY ANALYSIS; ONCOGENE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; FUNGI; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICROARRAY ANALYSIS; MICRORNAS;

FUNGI;

EID: 84863016511     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.697     Document Type: Article

References (63)

1. Furumai T, Igarashi Y, Higuchi H, Saito N and Oki T: Kosinostatin, a quinocycline antibiotic with antitumor activity from Micromonospora sp. TP-A0468. J Antibiot 55: 128-133, 2002. (Pubitemid 34285450)
2. Williams PG, Buchanan GO, Feling RH, Kauffman CA, Jensen PR and Fenical W: New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica. J Org Chem 70: 6196-6203, 2005. (Pubitemid 41076500)
3. Fenical W and Jensen PR: Developing a new resource for drug discovery: marine actinomycete bacteria. Nat Chem Biol 2: 666-673, 2006. (Pubitemid 44764208)
4. Blunt JW, Copp BR, Hu WP, Munro MH, Northcote PT and Prinsep MR: Marine natural products. Nat Prod Rep 24: 31-86, 2007. (Pubitemid 46238589)
5. Ambros V: The functions of animal microRNAs. Nature 431: 350-355, 2004.
6. Zhang B, Stellwag EJ and Pan X: Large-scale genome analysis reveals unique features of microRNAs. Gene 443: 100-109, 2009.
7. Ambros V: microRNAs: tiny regulators with great potential. Cell 107: 823-826, 2001.
8. Zhang B, Wang Q and Pan X: MicroRNAs and their regulatory roles in animals and plants. J Cell Physiol 210: 279-289, 2007. (Pubitemid 44956872)
9. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP and Burge CB: Prediction of mammalian microRNA targets. Cell 115: 787-798, 2003. (Pubitemid 38058492)
10. Hatfield SD, Shcherbata HR, Fischer KA, Nakahara K, Carthew RW and Ruohola-Baker H: Stem cell division is regulated by the microRNA pathway. Nature 435: 974-978, 2005. (Pubitemid 40896325)
11. Hwang HW and Mendell JT: MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 94: 776-780, 2006.
12. Leung AK, Calabrese JM and Sharp PA: Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci USA 103: 18125-18130, 2006. (Pubitemid 44871623)
13. Leung AK and Sharp PA: microRNAs: a safeguard against turmoil? Cell 130: 581-585, 2007. (Pubitemid 47268068)
14. Zhang B, Pan X and Anderson TA: MicroRNA: a new player in stem cells. J Cell Physiol 209: 266-269, 2006. (Pubitemid 44484616)
15. Calin GA, Sevignani C, Dumitru CD, et al: Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101: 2999-3004, 2004. (Pubitemid 38327724)
16. Calin GA, Dumitru CD, Shimizu M, et al: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99: 15524-15529, 2002. (Pubitemid 35403967)
17. Calin GA and Croce CM: MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866, 2006. (Pubitemid 44629897)
18. Cheng AM, Byrom MW, Shelton J and Ford LP: Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 33: 1290-1297, 2005. (Pubitemid 41439922)
19. Blenkiron C and Miska EA: miRNAs in cancer: approaches, aetiology, diagnostics and therapy. Hum Mol Genet 16 Spec No 1: R106-R113, 2007. (Pubitemid 47241849)
20. Iorio MV, Ferracin M, Liu CG, et al: MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65: 7065-7070, 2005. (Pubitemid 41161233)
21. Lu J, Getz G, Miska EA, et al: MicroRNA expression profiles classify human cancers. Nature 435: 834-838, 2005. (Pubitemid 40839735)
22. Zhang B, Pan X, Cobb GP and Anderson TA: microRNAs as oncogenes and tumor suppressors. Dev Biol 302: 1-12, 2007. (Pubitemid 46096921)
23. Zhang B and Farwell MA: microRNAs: a new emerging class of players for disease diagnostics and gene therapy. J Cell Mol Med 12: 3-21, 2008.
24. Ma L, Teruya-Feldstein J and Weinberg RA: Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688, 2007. (Pubitemid 47552092)
25. Huang Q, Gumireddy K, Schrier M, et al: The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 10: 202-210, 2008. (Pubitemid 351194050)
26. Tavazoie SF, Alarcon C, Oskarsson T, et al: Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451: 147-152, 2008.
27. Meng F, Henson R, Lang M, et al: Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 130: 2113-2129, 2006. (Pubitemid 43816961)
28. Blower PE, Verducci JS, Lin S, et al: MicroRNA expression profiles for the NCI-60 cancer cell panel. Mol Cancer Ther 6: 1483-1491, 2007. (Pubitemid 46954015)
29. Blower PE, Chung JH, Verducci JS, et al: MicroRNAs modulate the chemosensitivity of tumor cells. Mol Cancer Ther 7: 1-9, 2008.
30. Si ML, Zhu S, Wu H, Lu Z, Wu F and Mo YY: miR-21-mediated tumor growth. Oncogene 26: 2799-2803, 2007. (Pubitemid 46663837)
31. Li Y, Zhu X, Gu J, et al: Anti-miR-21 oligonucleotide enhances chemosensitivity of leukemic HL60 cells to arabinosylcytosine by inducing apoptosis. Hematology 15: 215-221, 2010.
32. Kovalchuk O, Filkowski J, Meservy J, et al: Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol Cancer Ther 7: 2152-2159, 2008.
33. Miller TE, Ghoshal K, Ramaswamy B, et al: MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem 283: 29897-29903, 2008.
34. Zhao JJ, Lin J, Yang H, et al: MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem 283: 31079-31086, 2008.
35. Xia L, Zhang D, Du R, et al: miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 123: 372-379, 2008. (Pubitemid 351842022)
36. Rossi L, Bonmassar E and Faraoni I: Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro. Pharmacol Res 56: 248-253, 2007. (Pubitemid 47321208)
37. Shah MY, Pan X, Fix LN, Farwell MA and Zhang B: 5-Fluorouracil drug alters the microRNA expression profiles in MCF-7 breast cancer cells. J Cell Physiol: Nov, 2010 (E-pub ahead of print).
38. Gao X, Gulari E and Zhou X: In situ synthesis of oligonucleotide microarrays. Biopolymers 73: 579-596, 2004. (Pubitemid 38480705)
39. Bolstad BM, Irizarry RA, Astrand M and Speed TP: A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19: 185-193, 2003. (Pubitemid 36181903)
40. Tricoli JV and Jacobson JW: MicroRNA: potential for cancer detection, diagnosis, and prognosis. Cancer Res 67: 4553-4555, 2007. (Pubitemid 46910157)
41. Lowery AJ, Miller N, McNeill RE and Kerin MJ: MicroRNAs as prognostic indicators and therapeutic targets: potential effect on breast cancer management. Clin Cancer Res 14: 360-365, 2008. (Pubitemid 351226101)
42. Cimmino A, Calin GA, Fabbri M, et al: miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102: 13944-13949, 2005. (Pubitemid 41377683)
43. Aqeilan RI, Calin GA and Croce CM: miR-15a and miR-16-1 in cancer: discovery, function and future perspectives. Cell Death Differ 17: 215-220, 2010.
44. Xia H, Qi Y, Ng SS, et al: MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells. Biochem Biophys Res Commun 380: 205-210, 2009.
45. Johnson SM, Grosshans H, Shingara J, et al: RAS is regulated by the let-7 microRNA family. Cell 120: 635-647, 2005. (Pubitemid 40343076)
46. Lee YS and Dutta A: The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 21: 1025-1030, 2007.
47. Sampson VB, Rong NH, Han J, et al: MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 67: 9762-9770, 2007. (Pubitemid 47621223)
48. Takamizawa J, Konishi H, Yanagisawa K, et al: Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64: 3753-3756, 2004. (Pubitemid 38697282)
49. Akao Y, Nakagawa Y and Naoe T: let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol Pharm Bull 29: 903-906, 2006.
50. Mertens-Talcott SU, Chintharlapalli S, Li X and Safe S: The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res 67: 11001-11011, 2007. (Pubitemid 350145930)
51. Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST and Patel T: MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658, 2007. (Pubitemid 47187346)
52. Zhu S, Si ML, Wu H and Mo YY: MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 282: 14328-14336, 2007. (Pubitemid 47100416)
53. Asangani IA, Rasheed SA, Nikolova DA, et al: MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2136, 2008. (Pubitemid 351485639)
54. Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A and Lund AH: Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 283: 1026-1033, 2008.
55. Lu Z, Liu M, Stribinskis V, et al: MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 27: 4373-4379, 2008. (Pubitemid 352010003)
56. Pan J, Hu H, Zhou Z, et al: Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrest in human gastric cancer cells. Oncol Rep 24: 105-112, 2010.
57. Yoo YA, Kang MH, Kim JS and Oh SC: Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway. Carcinogenesis 29: 480-490, 2008. (Pubitemid 351404863)
58. Tili E, Michaille JJ, Alder H, et al: Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells. Biochem Pharmacol 80: 2057-2065, 2010.
59. Kefas B, Godlewski J, Comeau L, et al: microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res 68: 3566-3572, 2008.
60. Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS and Leedman PJ: Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J Biol Chem 284: 5731-5741, 2009.
61. Petrocca F, Visone R, Onelli MR, et al: E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 13: 272-286, 2008. (Pubitemid 351318375)
62. Fang L, Deng Z, Shatseva T, et al: MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-beta8. Oncogene 30: 806-821, 2011.
63. Nam EJ, Yoon H, Kim SW, et al: MicroRNA expression profiles in serous ovarian carcinoma. Clin Cancer Res 14: 2690-2695, 2008.