Anti-miR-21 oligonucleotide enhances chemosensitivity of leukemic HL60 cells to arabinosylcytosine by inducing apoptosis

Hematology

Volumn 15, Issue 4, 2010, Pages 215-221

  Li, Yumin ^a   Zhu, Xuejiao ^a   Gu, Jingyi ^a   Hu, Haiyan ^a   Dong, Dawei ^a   Yao, Junlin ^a   Lin, Chunyan ^a   Fei, Jia ^a  

^a MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

Author keywords

antisense; apoptosis; arabinosylcytosine; chemosensitivity; growth; HL60 cells; MicroRNA 21; oligonucleotide; PDCD4

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYTARABINE; MICRORNA 21;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CELL VIABILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN TARGETING; RECEPTOR UPREGULATION;

3' UNTRANSLATED REGIONS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL SURVIVAL; CYTARABINE; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; GENES, REPORTER; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MICRORNAS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OSMOLAR CONCENTRATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSFECTION; UP-REGULATION;

EID: 77955202734     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453310X12647083620840     Document Type: Article

References (32)

1. Chelliah J, Freemerman AJ, Wu-Pong S, Jarvis WD, Grant S. Potentiation of ara-C-induced apoptosis by the protein kinase C activator bryostatin 1 in human leukemia cells (HL-60) involves a process dependent upon c-Myc. Biochem Pharmacol 1997; 54: 563-573
2. Qin L, Zhang X, Zhang L. Downregulation of BMI-1 enhances 5-fluorouracil-induced apoptosis in nasopharyngeal carcinoma cells. Biochem Biophys Res Commun 2008; 371: 531-535
3. Martin-Aragon S, Mukherjee SK, Taylor BJ et al. Cytosine arabinoside (ara-C) resistance confers cross-resistance or collateral sensitivity to other classes of anti-leukemic drugs. Anticancer Res 2000; 20: 139-150
4. Zhao Y, Srivastava DA. Developmental view of microRNA function. Trends Biochem Sci 2007; 32: 189-197
5. Griffiths-Jones S, Grocock RJ, van Dongen S. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 2006; 34: 140-144
6. Yu ZB, Jian ZF, Shen SH. Global analysis of microRNA target gene expression reveals that miRNA targets are lower expressed in mature mouse and Drosophila tissues than in the embryos. Nucleic Acids Res 2007; 35: 152-164
7. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297
8. Harfe BD. MicroRNAs in vertebrate development. Curr Opin Genet Dev 2005; 15: 410-415
9. Blower PE, Chung JH, Verducci JS. MicroRNAs modulate the chemosensitivity of tumor cells. Mol Cancer Ther 2008; 7: 1-9
10. Zhu H, Wu H, Liu X, Evans BR, Medina DJ. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol 2008; 76: 582-588
11. Xia L, Zhang D, Du R et al. miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 2008; 123: 372-379
12. Lu Z, Liu M, Stribinskis V. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 2008; 27: 4373-4379
13. Manikandan J, Aarthi JJ, Kumar SD, Pushparaj PN. Oncomirs: the potential role of non-coding microRNAs in understanding cancer. Bioinformation 2008; 2: 330-334
14. Zhang B, Pan X, Cobb GP, Anderson TA. microRNAs as oncogenes and tumor suppressors. Dev Biol 2007; 302: 1-12
15. Kent OA, Mendell JT. A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene 2006; 25: 6188-6196
16. Si ML, Zhu S, Wu Z, Lu F, Mo YY. miR-21-mediated tumor growth. Oncogene 2007; 26: 2799-2803
17. Roldo C, Missiaglia E, Hagan JP, Falconi M, Capelli P, Bersani S. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 2006, 24: 4677-4684
18. Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005; 65: 6029-6033
19. Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 2006; 130: 2113-2129
20. Esquela-Kerscher A, Slack FJ. Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 2006; 6: 259-269
21. Asangani IA, Rasheed SA, Nikolova DA et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008; 27: 2128-2136
22. Fraser M, Leung BM, Yan X, Dan HC, Cheng JQ, Tsang BK. p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells. Cancer Res 2003; 63: 7081-7088
23. Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death. Cell 1993; 74: 609-619
24. Amundson SA, Myers TG, Scudiero DS, Kitada SJ, Reed JC, Fornace AJ. An informatics approach identifying markers of chemosensitivity in human cancer cell lines. Cancer Res 2000; 60: 6101-6110
25. Reed JC. Apoptosis-targeted therapies for cancer. Cancer Cell 2003; 3: 17-22
26. Bettaieb A, Dubrez-Daloz L, Launay S et al. Bcl-2 proteins: targets and tools for chemosensitisation of tumor cells. Curr Med Chem Anticancer Agents 2003; 3, 307-318
27. Park WH, Cho HY, Jung CW et al. Arsenic trioxide inhibits the growth of A498 renal cell carcinoma cells via cell cycle arrest or apoptosis. Biochem Biophys Res Commun 2003; 300: 230-235
28. Esau CC. Inhibition of microRNA with antisense oligonucleotides. Methods 2008; 44: 55-60
29. Davis S, Lollo B, Freier S. Improved targeting of miRNA with antisense oligonucleotides. Nucleic Acids Res 2006; 34: 2294-2304
30. Cheng AM, Byrom MW, Shelton J. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 2005; 33: 1290-1297
31. Krützfeldt J, Rajewsky N, Braich R et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005; 438: 685-689
32. Weiler J, Hunziker J, Hall J. Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? Gene Ther 2005; 13: 496-502