Channel-opening kinetic mechanism of wild-type GluK1 kainate receptors and a C-terminal mutant

Biochemistry

Volumn 51, Issue 3, 2012, Pages 761-768

  Han, Yan ^a,b   Wang, Congzhou ^a   Park, Jae Seon ^a   Niu, Li ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; C-TERMINUS; CHANNEL CLOSING; CHANNEL GATING; CHANNEL OPENING; CURRENT RESPONSE; ENDOPLASMIC RETICULUM; FUNCTIONAL CHANNELS; HEK293 CELLS; IONOTROPIC GLUTAMATE RECEPTORS; ISOFORMS; KINETIC MECHANISM; LOW LEVEL; RECEPTOR TRAFFICKING; SATURATING CONCENTRATION; SEQUENCE MOTIFS; SIGNAL SEQUENCE; SURFACE EXPRESSION; WILD TYPES;

AMINO ACIDS; CELL MEMBRANES; PHOTOLYSIS;

RATE CONSTANTS;

AMINO ACID; KAINIC ACID RECEPTOR; KAINIC ACID RECEPTOR GLUK1 2A; KAINIC ACID RECEPTOR GLUK1 2B; KAINIC ACID RECEPTOR GLUK1 CHANNEL; KAINIC ACID RECEPTOR GLUK2; MUTANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHANNEL GATING; EMBRYO; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NONHUMAN; PHOTOLYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; WILD TYPE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ENDOPLASMIC RETICULUM; GLUTAMIC ACID; HEK293 CELLS; HUMANS; ISOENZYMES; MUTATION; PEPTIDE FRAGMENTS; PHOTOLYSIS; PROTEIN TRANSPORT; RECEPTORS, KAINIC ACID; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84863015827     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201446z     Document Type: Article

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