Identification of a novel ligand binding motif in the transthyretin channel

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 1, 2010, Pages 100-110

  Lima, Luis Mauricio T R ^a   Silva, Vivian de Almeida ^a,b   Palmieri, Leonardo de Castro ^a   Oliveira, Maria Clara B R ^a   Foguel, Débora ^a   Polikarpov, Igor ^c  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO FEDERAL DE EDUCAÇÃO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Amyloid; Hormone binding site; Naphthalenesulfonate; Transthyretin

Indexed keywords

1 AMINO 5 NAPHTHALENE SULFONATE; 8 ANILINO 1 NAPHTHALENESULFONIC ACID; DICLOFENAC; NAPHTHALENE DERIVATIVE; PREALBUMIN; SULFATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; PROTEIN MOTIF; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMYLOID; AMYLOIDOSIS; ANILINO NAPHTHALENESULFONATES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; MODELS, MOLECULAR; NAPHTHALENESULFONATES; PREALBUMIN; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 72049099027     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.11.025     Document Type: Article

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