메뉴 건너뛰기




Volumn 432, Issue , 2012, Pages 382-388

In vitro biocompatibility of solid lipid nanoparticles

Author keywords

Cytotoxicity; MDCK cells; SLN; Vero cells

Indexed keywords

CELL LINEAGE; CELL VIABILITY; CELLULAR RESPONSE; CYTOTOXIC; CYTOTOXIC EFFECTS; DNA FRAGMENTATION; FIBROBLAST CELLS; IN-VITRO; IN-VIVO; MDCK CELLS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL METABOLISM; NANOSCALE STRUCTURE; SLN; SODIUM DODECYL SULFATE; SOLID LIPID NANOPARTICLE (SLN); SOLID LIPID NANOPARTICLES; VERO CELLS;

EID: 84862989472     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2012.06.018     Document Type: Article
Times cited : (37)

References (48)
  • 1
    • 79955481592 scopus 로고    scopus 로고
    • Toxic response of nickel nanoparticles in human lung epithelial A549 cells
    • Ahamed M. Toxic response of nickel nanoparticles in human lung epithelial A549 cells. Toxicol In Vitro 2011, 25:930-936.
    • (2011) Toxicol In Vitro , vol.25 , pp. 930-936
    • Ahamed, M.1
  • 2
    • 0032827410 scopus 로고    scopus 로고
    • Mitochondrial transport of cations: channels, exchangers, and permeability transition
    • Bernardi P. Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiol Rev 1999, 79:1127-1155.
    • (1999) Physiol Rev , vol.79 , pp. 1127-1155
    • Bernardi, P.1
  • 3
    • 33747189808 scopus 로고    scopus 로고
    • Cytotoxicity and related effects of T-2 toxin on cultured Vero cells
    • Bouaziz C., Abid-Essefi S., Bouslimi A., El Golli E., Bacha H. Cytotoxicity and related effects of T-2 toxin on cultured Vero cells. Toxicon 2006, 48:343-352.
    • (2006) Toxicon , vol.48 , pp. 343-352
    • Bouaziz, C.1    Abid-Essefi, S.2    Bouslimi, A.3    El Golli, E.4    Bacha, H.5
  • 4
    • 77955086453 scopus 로고    scopus 로고
    • Evaluation of DNA damage and cytotoxicity of polyurethane-based nano- and microparticles as promising biomaterials for drug delivery systems
    • Caon T., Zanetti-Ramos B.G., Lemos-Senna E., Cloutet E., Cramail H., Borsali R., et al. Evaluation of DNA damage and cytotoxicity of polyurethane-based nano- and microparticles as promising biomaterials for drug delivery systems. J Nanopart Res 2010, 12:10.
    • (2010) J Nanopart Res , vol.12 , pp. 10
    • Caon, T.1    Zanetti-Ramos, B.G.2    Lemos-Senna, E.3    Cloutet, E.4    Cramail, H.5    Borsali, R.6
  • 5
    • 34547905415 scopus 로고    scopus 로고
    • Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system
    • Chattopadhyay P., Shekunov B.Y., Yim D., Cipolla D., Boyd B., Farr S. Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system. Adv Drug Deliv Rev 2007, 59:444-453.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 444-453
    • Chattopadhyay, P.1    Shekunov, B.Y.2    Yim, D.3    Cipolla, D.4    Boyd, B.5    Farr, S.6
  • 7
    • 61449170919 scopus 로고    scopus 로고
    • Comparative study of the cytotoxic effect of microcistin-LR and purified extracts from Microcystis aeruginosa on a kidney cell line
    • Dias E., Andrade M., Alverca E., Pereira P., Batoréu M.C., Jordan P., et al. Comparative study of the cytotoxic effect of microcistin-LR and purified extracts from Microcystis aeruginosa on a kidney cell line. Toxicon 2009, 53:487-495.
    • (2009) Toxicon , vol.53 , pp. 487-495
    • Dias, E.1    Andrade, M.2    Alverca, E.3    Pereira, P.4    Batoréu, M.C.5    Jordan, P.6
  • 8
    • 84855813140 scopus 로고    scopus 로고
    • Albumin-based nanoparticles as potential controlled release drug delivery systems
    • Elzoghby A.O., Samy W.M., Elgindy N.A. Albumin-based nanoparticles as potential controlled release drug delivery systems. J Control Release 2012, 157:168-182.
    • (2012) J Control Release , vol.157 , pp. 168-182
    • Elzoghby, A.O.1    Samy, W.M.2    Elgindy, N.A.3
  • 9
    • 76749110662 scopus 로고    scopus 로고
    • Better safe than sorry: understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications
    • Fadeel B., Garcia-Bennett A.E. Better safe than sorry: understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. Adv Drug Deliv Rev 2010, 62:362-374.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 362-374
    • Fadeel, B.1    Garcia-Bennett, A.E.2
  • 10
    • 77956178863 scopus 로고    scopus 로고
    • Oxidative stress induction by nanoparticles in THP-1 cells with 4-HNE production: stress biomarker or oxidative stress signalling molecule?
    • Foucaud L., Goulaouic S., Bennasroune A., Laval-Gilly P., Brown D., Stone V., et al. Oxidative stress induction by nanoparticles in THP-1 cells with 4-HNE production: stress biomarker or oxidative stress signalling molecule?. Toxicol In Vitro 2010, 24:1512-1520.
    • (2010) Toxicol In Vitro , vol.24 , pp. 1512-1520
    • Foucaud, L.1    Goulaouic, S.2    Bennasroune, A.3    Laval-Gilly, P.4    Brown, D.5    Stone, V.6
  • 12
    • 79851516126 scopus 로고    scopus 로고
    • Effects of various physicochemical characteristics on the toxicities of ZnO and TiO nanoparticles toward human lung epithelial cells
    • Hsiao I.L., Huang Y.J. Effects of various physicochemical characteristics on the toxicities of ZnO and TiO nanoparticles toward human lung epithelial cells. Sci Total Environ 2011, 409:1219-1228.
    • (2011) Sci Total Environ , vol.409 , pp. 1219-1228
    • Hsiao, I.L.1    Huang, Y.J.2
  • 13
    • 61449116709 scopus 로고    scopus 로고
    • In vitro evaluation of cytotoxicity of engineered metal oxide nanoparticles
    • Hu X., Cook S., Wang P., Hwang H.M. In vitro evaluation of cytotoxicity of engineered metal oxide nanoparticles. Sci Total Environ 2009, 407:3070-3072.
    • (2009) Sci Total Environ , vol.407 , pp. 3070-3072
    • Hu, X.1    Cook, S.2    Wang, P.3    Hwang, H.M.4
  • 14
    • 46549085541 scopus 로고    scopus 로고
    • A bioassay for the simultaneous measurement of metabolic activity, membrane integrity, and lysosomal activity in cell cultures
    • Ivanova L., Uhlig S. A bioassay for the simultaneous measurement of metabolic activity, membrane integrity, and lysosomal activity in cell cultures. Anal Biochem 2008, 379:16-19.
    • (2008) Anal Biochem , vol.379 , pp. 16-19
    • Ivanova, L.1    Uhlig, S.2
  • 15
    • 59649097447 scopus 로고    scopus 로고
    • Lipid nanoparticles for parenteral delivery of actives
    • Joshi M.D., Müller R.H. Lipid nanoparticles for parenteral delivery of actives. Eur J Pharm Biopharm 2009, 71:161-172.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 161-172
    • Joshi, M.D.1    Müller, R.H.2
  • 16
    • 77949915304 scopus 로고    scopus 로고
    • From ecotoxicology to nanoecotoxicology
    • Kahru A., Dubourguier H.-C. From ecotoxicology to nanoecotoxicology. Toxicology 2010, 269:105-119.
    • (2010) Toxicology , vol.269 , pp. 105-119
    • Kahru, A.1    Dubourguier, H.-C.2
  • 17
    • 13844297094 scopus 로고    scopus 로고
    • The impact of nanobiotechnology on the development of new drug delivery systems
    • Kayser O., Lemke A., Hernández-Trejo N. The impact of nanobiotechnology on the development of new drug delivery systems. Curr Pharm Biotechnol 2005, 6:3-5.
    • (2005) Curr Pharm Biotechnol , vol.6 , pp. 3-5
    • Kayser, O.1    Lemke, A.2    Hernández-Trejo, N.3
  • 18
    • 42749097321 scopus 로고    scopus 로고
    • In vivo time-dependent gene expression of cationic lipid-based emulsion as a stable and biocompatible non-viral gene carrier
    • Kwon S.M., Nam H.Y., Nam T., Park K., Lee S., Kim K., et al. In vivo time-dependent gene expression of cationic lipid-based emulsion as a stable and biocompatible non-viral gene carrier. J Control Release 2008, 128:89-97.
    • (2008) J Control Release , vol.128 , pp. 89-97
    • Kwon, S.M.1    Nam, H.Y.2    Nam, T.3    Park, K.4    Lee, S.5    Kim, K.6
  • 19
    • 42649135116 scopus 로고    scopus 로고
    • Solid lipid nanoparticles for pulmonary delivery of insulin
    • Liu J., Gong T., Fu H., Wang C., Wang X., Chen Q., et al. Solid lipid nanoparticles for pulmonary delivery of insulin. Int J Pharm 2008, 356:333-344.
    • (2008) Int J Pharm , vol.356 , pp. 333-344
    • Liu, J.1    Gong, T.2    Fu, H.3    Wang, C.4    Wang, X.5    Chen, Q.6
  • 20
    • 84860780308 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway
    • Martins S., Costa-Lima S., Carneiro T., Cordeiro-da-Silva A., Souto E.B., Ferreira D.C. Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway. Int J Pharm 2012, 430:216-227.
    • (2012) Int J Pharm , vol.430 , pp. 216-227
    • Martins, S.1    Costa-Lima, S.2    Carneiro, T.3    Cordeiro-da-Silva, A.4    Souto, E.B.5    Ferreira, D.C.6
  • 21
    • 14644396096 scopus 로고    scopus 로고
    • Nanomedicine: current status and future prospects
    • Moghimi S.M., Hunter A.C., Murray J.C. Nanomedicine: current status and future prospects. FASEB J 2005, 19:311-330.
    • (2005) FASEB J , vol.19 , pp. 311-330
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 22
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 23
    • 33744973517 scopus 로고    scopus 로고
    • Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals
    • Müller R.H., Runge S., Ravelli V., Mehnert W., Thünemann A.F., Souto E.B. Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals. Int J Pharm 2006, 317:82-89.
    • (2006) Int J Pharm , vol.317 , pp. 82-89
    • Müller, R.H.1    Runge, S.2    Ravelli, V.3    Mehnert, W.4    Thünemann, A.F.5    Souto, E.B.6
  • 24
    • 77952896692 scopus 로고    scopus 로고
    • A toxicological evaluation of inhaled solid lipid nanoparticles used as a potential drug delivery system for the lung
    • Nassimi M., Schleh C., Lauenstein H.D., Hussein R., Hoymann H.G., Koch W., et al. A toxicological evaluation of inhaled solid lipid nanoparticles used as a potential drug delivery system for the lung. Eur J Pharm Biopharm 2010, 75:107-116.
    • (2010) Eur J Pharm Biopharm , vol.75 , pp. 107-116
    • Nassimi, M.1    Schleh, C.2    Lauenstein, H.D.3    Hussein, R.4    Hoymann, H.G.5    Koch, W.6
  • 25
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • Nel A., Xia T., Mädler L., Li N. Toxic potential of materials at the nanolevel. Science 2006, 311:622-627.
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Mädler, L.3    Li, N.4
  • 26
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles
    • Oberdörster G., Oberdörster E., Oberdörster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 2005, 113:823-839.
    • (2005) Environ Health Perspect , vol.113 , pp. 823-839
    • Oberdörster, G.1    Oberdörster, E.2    Oberdörster, J.3
  • 27
    • 0036643948 scopus 로고    scopus 로고
    • Investigating the relationship between the cell cycle and apoptosis using flow cytometry
    • Ormerod M.G. Investigating the relationship between the cell cycle and apoptosis using flow cytometry. J Immunol Methods 2002, 265:73-80.
    • (2002) J Immunol Methods , vol.265 , pp. 73-80
    • Ormerod, M.G.1
  • 28
    • 57849099131 scopus 로고    scopus 로고
    • Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products
    • Pardeike J., Hommoss A., Müller R.H. Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int J Pharm 2009, 366:170-184.
    • (2009) Int J Pharm , vol.366 , pp. 170-184
    • Pardeike, J.1    Hommoss, A.2    Müller, R.H.3
  • 29
    • 49749131612 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells
    • Park E.J., Yi J., Chung K.H., Ryu D.Y., Choi J., Park K. Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. Toxicol Lett 2008, 180:222-229.
    • (2008) Toxicol Lett , vol.180 , pp. 222-229
    • Park, E.J.1    Yi, J.2    Chung, K.H.3    Ryu, D.Y.4    Choi, J.5    Park, K.6
  • 30
    • 50249171227 scopus 로고    scopus 로고
    • Neutral red uptake assay for the estimation of cell viability/cytotoxicity
    • Repetto G., del Peso A., Zurita J.L. Neutral red uptake assay for the estimation of cell viability/cytotoxicity. Nat Protoc 2008, 3:1125-1131.
    • (2008) Nat Protoc , vol.3 , pp. 1125-1131
    • Repetto, G.1    del Peso, A.2    Zurita, J.L.3
  • 32
    • 0036379302 scopus 로고    scopus 로고
    • Cyclosporine A-induced toxicity in two renal cell culture models (LLC-PK1 and MDCK)
    • Rezzani R., Angoscini P., Borsani E., Rodella L., Bianchi R. Cyclosporine A-induced toxicity in two renal cell culture models (LLC-PK1 and MDCK). Histochem J 2002, 34:27-33.
    • (2002) Histochem J , vol.34 , pp. 27-33
    • Rezzani, R.1    Angoscini, P.2    Borsani, E.3    Rodella, L.4    Bianchi, R.5
  • 35
    • 0042829414 scopus 로고    scopus 로고
    • Regulation of intrinsic prion protein by growth factors and TNF-alpha: the role of intracellular reactive oxygen species
    • Sauer H., Wefer K., Vetrugno V., Pocchiari M., Gissel C., Sachinidis A., et al. Regulation of intrinsic prion protein by growth factors and TNF-alpha: the role of intracellular reactive oxygen species. Free Radic Biol Med 2003, 35:586-594.
    • (2003) Free Radic Biol Med , vol.35 , pp. 586-594
    • Sauer, H.1    Wefer, K.2    Vetrugno, V.3    Pocchiari, M.4    Gissel, C.5    Sachinidis, A.6
  • 36
    • 78650519473 scopus 로고    scopus 로고
    • ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells
    • Shukla R.K., Sharma V., Pandey A.K., Singh S., Sultana S., Dhawan A. ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells. Toxicol In Vitro 2011, 25:231-241.
    • (2011) Toxicol In Vitro , vol.25 , pp. 231-241
    • Shukla, R.K.1    Sharma, V.2    Pandey, A.K.3    Singh, S.4    Sultana, S.5    Dhawan, A.6
  • 37
    • 59349112696 scopus 로고    scopus 로고
    • Potential method to determine irritant potency in vitro - comparison of two reconstructed epidermal culture models with different barrier competency
    • Spiekstra S.W., Dos Santos G.G., Scheper R.J., Gibbs S. Potential method to determine irritant potency in vitro - comparison of two reconstructed epidermal culture models with different barrier competency. Toxicol In Vitro 2009, 23:349-355.
    • (2009) Toxicol In Vitro , vol.23 , pp. 349-355
    • Spiekstra, S.W.1    Dos Santos, G.G.2    Scheper, R.J.3    Gibbs, S.4
  • 38
    • 79953747559 scopus 로고    scopus 로고
    • Induction of mitochondrial destabilization and necrotic cell death by apolar mitochondria-directed SOD mimetics
    • Szabo A., Balog M., Mark L., Montsko G., Turi Z., Gallyas F., et al. Induction of mitochondrial destabilization and necrotic cell death by apolar mitochondria-directed SOD mimetics. Mitochondrion 2011, 11:476-487.
    • (2011) Mitochondrion , vol.11 , pp. 476-487
    • Szabo, A.1    Balog, M.2    Mark, L.3    Montsko, G.4    Turi, Z.5    Gallyas, F.6
  • 40
    • 32444433202 scopus 로고    scopus 로고
    • Free radicals, metals and antioxidants in oxidative stress-induced cancer
    • Valko M., Rhodes C.J., Moncol J., Izakovic M., Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 2006, 160:1-40.
    • (2006) Chem Biol Interact , vol.160 , pp. 1-40
    • Valko, M.1    Rhodes, C.J.2    Moncol, J.3    Izakovic, M.4    Mazur, M.5
  • 41
    • 76749166182 scopus 로고    scopus 로고
    • Investigation of the cytotoxicity of antimicrobial peptide P40 on eukaryotic cells
    • Vaucher R.A., Teixeira M.L., Brandelli A. Investigation of the cytotoxicity of antimicrobial peptide P40 on eukaryotic cells. Curr Microbiol 2010, 60:1-5.
    • (2010) Curr Microbiol , vol.60 , pp. 1-5
    • Vaucher, R.A.1    Teixeira, M.L.2    Brandelli, A.3
  • 42
    • 84866515787 scopus 로고    scopus 로고
    • Preclinical evaluation of a pulmonary delivered paclitaxel-loaded lipid nanocarrier antitumor effect
    • in press.
    • Videira M, Almeida AJ, Fabra A. Preclinical evaluation of a pulmonary delivered paclitaxel-loaded lipid nanocarrier antitumor effect. Nanomed Nanotechnol Biol Med in press. http://dx.doi.org/10.1016/j.nano.2012.12.007.
    • Nanomed Nanotechnol Biol Med.
    • Videira, M.1    Almeida, A.J.2    Fabra, A.3
  • 43
    • 77953683770 scopus 로고    scopus 로고
    • Targeting nanoparticles to cancer
    • Wang M., Thanou M. Targeting nanoparticles to cancer. Pharmacol Res 2010, 62:90-99.
    • (2010) Pharmacol Res , vol.62 , pp. 90-99
    • Wang, M.1    Thanou, M.2
  • 44
    • 67649370750 scopus 로고    scopus 로고
    • Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells
    • Wang F., Gao F., Lan M., Yuan H., Huang Y., Liu J. Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells. Toxicol In Vitro 2009, 23:808-815.
    • (2009) Toxicol In Vitro , vol.23 , pp. 808-815
    • Wang, F.1    Gao, F.2    Lan, M.3    Yuan, H.4    Huang, Y.5    Liu, J.6
  • 45
    • 79957691069 scopus 로고    scopus 로고
    • Physical and chemical stability of drug nanoparticles
    • Wu L., Zhang J., Watanabe W. Physical and chemical stability of drug nanoparticles. Adv Drug Deliv Rev 2011, 63:456-469.
    • (2011) Adv Drug Deliv Rev , vol.63 , pp. 456-469
    • Wu, L.1    Zhang, J.2    Watanabe, W.3
  • 46
    • 34548672367 scopus 로고    scopus 로고
    • 23,24-Dihydrocucurbitacin B induces G2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37)
    • Yang L., Wu S., Zhang Q., Liu F., Wu P. 23,24-Dihydrocucurbitacin B induces G2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37). Cancer Lett 2007, 256:267-278.
    • (2007) Cancer Lett , vol.256 , pp. 267-278
    • Yang, L.1    Wu, S.2    Zhang, Q.3    Liu, F.4    Wu, P.5
  • 47
    • 77952741502 scopus 로고    scopus 로고
    • Ternary nanoparticles of anionic lipid nanoparticles/protamine/DNA for gene delivery
    • Yuan H., Zhang W., Du Y.Z., Hu F.Q. Ternary nanoparticles of anionic lipid nanoparticles/protamine/DNA for gene delivery. Int J Pharm 2010, 392:224-231.
    • (2010) Int J Pharm , vol.392 , pp. 224-231
    • Yuan, H.1    Zhang, W.2    Du, Y.Z.3    Hu, F.Q.4
  • 48
    • 0141447370 scopus 로고    scopus 로고
    • Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis
    • Zhao M., Antunes F., Eaton J.W., Brunk U.T. Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. Eur J Biochem 2003, 270:3778-3786.
    • (2003) Eur J Biochem , vol.270 , pp. 3778-3786
    • Zhao, M.1    Antunes, F.2    Eaton, J.W.3    Brunk, U.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.