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Volumn 36, Issue 1, 2012, Pages 78-85

Sun ginseng protects endothelial progenitor cells from senescence associated apoptosis

Author keywords

Aging; Apoptosis; Endothelial progenitor cells (EPCs); Panax ginseng; Sun ginseng

Indexed keywords

PANAX GINSENG; ULEX; ULEX EUROPAEUS;

EID: 84862974914     PISSN: 12268453     EISSN: None     Source Type: Journal    
DOI: 10.5142/jgr.2012.36.1.78     Document Type: Article
Times cited : (19)

References (54)
  • 4
    • 17644433975 scopus 로고    scopus 로고
    • Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    • Vasa, M., Fichtlscherer, S., Aicher, A., Adler, K., Urbich, C., Martin, H., Zeiher, A. M. and Dimmeler, S., Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease, Circ Res 2001;89:E1-7.
    • (2001) Circ Res , vol.89
    • Vasa, M.1    Fichtlscherer, S.2    Aicher, A.3    Adler, K.4    Urbich, C.5    Martin, H.6    Zeiher, A.M.7    Dimmeler, S.8
  • 5
    • 0033857389 scopus 로고    scopus 로고
    • Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice
    • Schatteman, G. C., Hanlon, H. D., Jiao, C., Dodds, S. G. and Christy, B. A., Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice, J Clin Invest 2000;106:571-578.
    • (2000) J Clin Invest , vol.106 , pp. 571-578
    • Schatteman, G.C.1    Hanlon, H.D.2    Jiao, C.3    Dodds, S.G.4    Christy, B.A.5
  • 6
    • 0037180517 scopus 로고    scopus 로고
    • Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures
    • Tepper, O. M., Galiano, R. D., Capla, J. M., Kalka, C., Gagne, P. J., Jacobowitz, G. R., Levine, J. P. and Gurtner, G. C., Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures, Circulation 2002;106:2781-2786.
    • (2002) Circulation , vol.106 , pp. 2781-2786
    • Tepper, O.M.1    Galiano, R.D.2    Capla, J.M.3    Kalka, C.4    Gagne, P.J.5    Jacobowitz, G.R.6    Levine, J.P.7    Gurtner, G.C.8
  • 10
    • 0030942927 scopus 로고    scopus 로고
    • Ginsenoside-Rg5 suppresses cyclin E-dependent protein kinase activity via up-regulating p21Cip/WAF1 and down-regulating cyclin E in SK-HEP-1 cells
    • Lee, K. Y., Lee, Y. H., Kim, S. I., Park, J. H. and Lee, S. K., Ginsenoside-Rg5 suppresses cyclin E-dependent protein kinase activity via up-regulating p21Cip/WAF1 and down-regulating cyclin E in SK-HEP-1 cells, Anticancer Res 1997;17:1067-1072.
    • (1997) Anticancer Res , vol.17 , pp. 1067-1072
    • Lee, K.Y.1    Lee, Y.H.2    Kim, S.I.3    Park, J.H.4    Lee, S.K.5
  • 11
    • 0034604516 scopus 로고    scopus 로고
    • Anti-proliferative effect of ginseng saponins on human prostate cancer cell line
    • Liu, W. K., Xu, S. X. and Che, C. T., Anti-proliferative effect of ginseng saponins on human prostate cancer cell line, Life Sci 2000;67:1297-1306.
    • (2000) Life Sci , vol.67 , pp. 1297-1306
    • Liu, W.K.1    Xu, S.X.2    Che, C.T.3
  • 12
    • 34247365969 scopus 로고    scopus 로고
    • Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer
    • Xu, T. M., Xin, Y., Cui, M. H., Jiang, X. and Gu, L. P., Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer, Chin Med J (Engl) 2007;120:584-588.
    • (2007) Chin Med J (Engl) , vol.120 , pp. 584-588
    • Xu, T.M.1    Xin, Y.2    Cui, M.H.3    Jiang, X.4    Gu, L.P.5
  • 13
    • 75949095715 scopus 로고    scopus 로고
    • KG-135, enriched with selected ginsenosides, inhibits the proliferation of human prostate cancer cells in culture and inhibits xenograft growth in athymic mice
    • Yoo, J. H., Kwon, H. C., Kim, Y. J., Park, J. H. and Yang, H. O., KG-135, enriched with selected ginsenosides, inhibits the proliferation of human prostate cancer cells in culture and inhibits xenograft growth in athymic mice, Cancer Lett;289:99-110.
    • Cancer Lett , vol.289 , pp. 99-110
    • Yoo, J.H.1    Kwon, H.C.2    Kim, Y.J.3    Park, J.H.4    Yang, H.O.5
  • 15
    • 33750292972 scopus 로고    scopus 로고
    • Cell death in the nervous system
    • Bredesen, D. E., Rao, R. V. and Mehlen, P., Cell death in the nervous system, Nature 2006;443:796-802.
    • (2006) Nature , vol.443 , pp. 796-802
    • Bredesen, D.E.1    Rao, R.V.2    Mehlen, P.3
  • 16
    • 62349108598 scopus 로고    scopus 로고
    • Natural antioxidants protect neurons in Alzheimer's disease and Parkinson's disease
    • Zhao, B., Natural antioxidants protect neurons in Alzheimer's disease and Parkinson's disease, Neurochem Res 2009;34:630-638.
    • (2009) Neurochem Res , vol.34 , pp. 630-638
    • Zhao, B.1
  • 17
    • 0037418213 scopus 로고    scopus 로고
    • Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors
    • Rehman, J., Li, J., Orschell, C. M. and March, K. L., Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors, Circulation 2003;107:1164-1169.
    • (2003) Circulation , vol.107 , pp. 1164-1169
    • Rehman, J.1    Li, J.2    Orschell, C.M.3    March, K.L.4
  • 19
    • 24944526542 scopus 로고    scopus 로고
    • Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: The role of angiogenic cytokines and matrix metalloproteinases
    • Yoon, C. H., Hur, J., Park, K. W., Kim, J. H., Lee, C. S., Oh, I. Y., Kim, T. Y., Cho, H. J., Kang, H. J., Chae, I. H., Yang, H. K., Oh, B. H., Park, Y. B. and Kim, H. S., Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases, Circulation 2005;112:1618-1627.
    • (2005) Circulation , vol.112 , pp. 1618-1627
    • Yoon, C.H.1    Hur, J.2    Park, K.W.3    Kim, J.H.4    Lee, C.S.5    Oh, I.Y.6    Kim, T.Y.7    Cho, H.J.8    Kang, H.J.9    Chae, I.H.10    Yang, H.K.11    Oh, B.H.12    Park, Y.B.13    Kim, H.S.14
  • 20
    • 70450228666 scopus 로고    scopus 로고
    • American Ginseng inhibits induced COX-2 and NFKB activation in breast cancer cells
    • Peralta, E. A., Murphy, L. L., Minnis, J., Louis, S. and Dunnington, G. L., American Ginseng inhibits induced COX-2 and NFKB activation in breast cancer cells, J Surg Res 2009;157:261-267.
    • (2009) J Surg Res , vol.157 , pp. 261-267
    • Peralta, E.A.1    Murphy, L.L.2    Minnis, J.3    Louis, S.4    Dunnington, G.L.5
  • 21
    • 0034047551 scopus 로고    scopus 로고
    • Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng
    • Keum, Y. S., Park, K. K., Lee, J. M., Chun, K. S., Park, J. H., Lee, S. K., Kwon, H. and Surh, Y. J., Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng, Cancer Lett 2000;150:41-48.
    • (2000) Cancer Lett , vol.150 , pp. 41-48
    • Keum, Y.S.1    Park, K.K.2    Lee, J.M.3    Chun, K.S.4    Park, J.H.5    Lee, S.K.6    Kwon, H.7    Surh, Y.J.8
  • 22
    • 0034713329 scopus 로고    scopus 로고
    • Is beta-galactosidase staining a marker of senescence in vitro and in vivo?
    • Severino, J., Allen, R. G., Balin, S., Balin, A. and Cristofalo, V. J., Is beta-galactosidase staining a marker of senescence in vitro and in vivo?, Exp Cell Res 2000;257:162-171.
    • (2000) Exp Cell Res , vol.257 , pp. 162-171
    • Severino, J.1    Allen, R.G.2    Balin, S.3    Balin, A.4    Cristofalo, V.J.5
  • 25
    • 46349093667 scopus 로고    scopus 로고
    • Different fibrillar Abeta 1-42 concentrations induce adult hippocampal neurons to reenter various phases of the cell cycle
    • Majd, S., Zarifkar, A., Rastegar, K. and Takhshid, M. A., Different fibrillar Abeta 1-42 concentrations induce adult hippocampal neurons to reenter various phases of the cell cycle, Brain Res 2008;1218:224-229.
    • (2008) Brain Res , vol.1218 , pp. 224-229
    • Majd, S.1    Zarifkar, A.2    Rastegar, K.3    Takhshid, M.A.4
  • 26
    • 33746468121 scopus 로고    scopus 로고
    • Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloidbeta peptide 1-42-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease
    • Abdul, H. M., Calabrese, V., Calvani, M. and Butterfield, D. A., Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloidbeta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease, J Neurosci Res 2006;84:398-408.
    • (2006) J Neurosci Res , vol.84 , pp. 398-408
    • Abdul, H.M.1    Calabrese, V.2    Calvani, M.3    Butterfield, D.A.4
  • 27
    • 78049296008 scopus 로고    scopus 로고
    • Puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo
    • Li, J., Wang, G., Liu, J., Zhou, L., Dong, M., Wang, R., Li, X., Li, X., Lin, C. and Niu, Y., Puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo, Eur J Pharmacol;649:195-201.
    • Eur J Pharmacol , vol.649 , pp. 195-201
    • Li, J.1    Wang, G.2    Liu, J.3    Zhou, L.4    Dong, M.5    Wang, R.6    Li, X.7    Li, X.8    Lin, C.9    Niu, Y.10
  • 28
    • 13544268711 scopus 로고    scopus 로고
    • Inhibitors beta-amyloid-induced toxicity by modulating the Akt signaling pathway
    • Nakagami, Y., Inhibitors beta-amyloid-induced toxicity by modulating the Akt signaling pathway, Drug News Perspect 2004;17:655-660.
    • (2004) Drug News Perspect , vol.17 , pp. 655-660
    • Nakagami, Y.1
  • 29
    • 34249828655 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative disease
    • Burke, R. E., Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative disease, Pharmacol Ther 2007;114:261-277.
    • (2007) Pharmacol Ther , vol.114 , pp. 261-277
    • Burke, R.E.1
  • 31
    • 33947623671 scopus 로고    scopus 로고
    • Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders
    • Mattson, M. P., Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders, Antioxid Redox Signal 2006;8:1997-2006.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1997-2006
    • Mattson, M.P.1
  • 32
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders
    • Mattson, M. P., Apoptosis in neurodegenerative disorders, Nat Rev Mol Cell Biol 2000;1:120-129.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 120-129
    • Mattson, M.P.1
  • 33
    • 37549015237 scopus 로고    scopus 로고
    • Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia
    • Zhang, G., Liu, A., Zhou, Y., San, X., Jin, T. and Jin, Y., Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia, J Ethnopharmacol 2008;115:441-448.
    • (2008) J Ethnopharmacol , vol.115 , pp. 441-448
    • Zhang, G.1    Liu, A.2    Zhou, Y.3    San, X.4    Jin, T.5    Jin, Y.6
  • 34
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman, G., Reutelingsperger, C. P., Kuijten, G. A., Keehnen, R. M., Pals, S. T. and van Oers, M. H., Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis, Blood 1994;84:1415-1420.
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.M.4    Pals, S.T.5    van Oers, M.H.6
  • 35
    • 0029043888 scopus 로고
    • A novel assay for apoptosis
    • Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
    • Vermes, I., Haanen, C., Steffens-Nakken, H. and Reutelingsperger, C., A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V, J Immunol Methods 1995;184:39-51.
    • (1995) J Immunol Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 37
    • 24144438187 scopus 로고    scopus 로고
    • Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity
    • Imanishi, T., Hano, T. and Nishio, I., Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity, J Hypertens 2005;23:1699-1706.
    • (2005) J Hypertens , vol.23
    • Imanishi, T.1    Hano, T.2    Nishio, I.3
  • 39
    • 0031935827 scopus 로고    scopus 로고
    • Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies
    • Gire, V. and Wynford-Thomas, D., Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies, Mol Cell Biol 1998;18:1611-1621.
    • (1998) Mol Cell Biol , vol.18 , pp. 1611-1621
    • Gire, V.1    Wynford-Thomas, D.2
  • 40
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D. and Lowe, S. W., Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a, Cell 1997;88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 41
    • 78651488113 scopus 로고    scopus 로고
    • Measurement of precuneal and hippocampal volumes using magnetic resonance volumetry in Alzheimer's disease
    • Ryu, S. Y., Kwon, M. J., Lee, S. B., Yang, D. W., Kim, T. W., Song, I. U., Yang, P. S., Kim, H. J. and Lee, A. Y., Measurement of precuneal and hippocampal volumes using magnetic resonance volumetry in Alzheimer's disease, J Clin Neurol 2010;6:196-203.
    • (2010) J Clin Neurol , vol.6 , pp. 196-203
    • Ryu, S.Y.1    Kwon, M.J.2    Lee, S.B.3    Yang, D.W.4    Kim, T.W.5    Song, I.U.6    Yang, P.S.7    Kim, H.J.8    Lee, A.Y.9
  • 42
    • 78651484664 scopus 로고    scopus 로고
    • Topographical dis orientation in mild cognitive impairment: A voxel-based morphometry study
    • Lim, T. S., Iaria, G. and Moon, S. Y., Topographical dis orientation in mild cognitive impairment: a voxel-based morphometry study, J Clin Neurol 2010;6:204-211.
    • (2010) J Clin Neurol , vol.6 , pp. 204-211
    • Lim, T.S.1    Iaria, G.2    Moon, S.Y.3
  • 43
    • 0035159785 scopus 로고    scopus 로고
    • Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease
    • Glabe, C., Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease, J Mol Neurosci 2001;17:137-145.
    • (2001) J Mol Neurosci , vol.17 , pp. 137-145
    • Glabe, C.1
  • 44
    • 36248971777 scopus 로고    scopus 로고
    • Mechanisms of amyloid plaque pathogenesis
    • Fiala, J. C., Mechanisms of amyloid plaque pathogenesis, Acta Neuropathol 2007;114:551-571.
    • (2007) Acta Neuropathol , vol.114 , pp. 551-571
    • Fiala, J.C.1
  • 45
    • 76749121072 scopus 로고    scopus 로고
    • Reduced circulating angiogenic cells in Alzheimer disease
    • author re- ply 346-347
    • Brenner, S. R., Roh, J. K., Lee, S. T., Chu, K., Jung, K. H., Lee, S. K. and Kim, M., Reduced circulating angiogenic cells in Alzheimer disease, Neurology;74:346; author re- ply 346-347.
    • Neurology , vol.74 , pp. 346
    • Brenner, S.R.1    Roh, J.K.2    Lee, S.T.3    Chu, K.4    Jung, K.H.5    Lee, S.K.6    Kim, M.7
  • 47
  • 49
    • 13544268809 scopus 로고    scopus 로고
    • Neurovascular mechanisms of Alzheimer's neurodegeneration
    • Zlokovic, B. V., Neurovascular mechanisms of Alzheimer's neurodegeneration, Trends Neurosci 2005;28:202-208.
    • (2005) Trends Neurosci , vol.28 , pp. 202-208
    • Zlokovic, B.V.1
  • 50
    • 4143052506 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Characterization and role in vascular biology
    • Urbich, C. and Dimmeler, S., Endothelial progenitor cells: characterization and role in vascular biology, Circ Res 2004;95:343-353.
    • (2004) Circ Res , vol.95 , pp. 343-353
    • Urbich, C.1    Dimmeler, S.2
  • 51
    • 54549111180 scopus 로고    scopus 로고
    • An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease
    • Heo, J. H., Lee, S. T., Chu, K., Oh, M. J., Park, H. J., Shim, J. Y. and Kim, M., An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease, Eur J Neurol 2008;15:865-868.
    • (2008) Eur J Neurol , vol.15 , pp. 865-868
    • Heo, J.H.1    Lee, S.T.2    Chu, K.3    Oh, M.J.4    Park, H.J.5    Shim, J.Y.6    Kim, M.7
  • 52
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • Kinnaird, T., Stabile, E., Burnett, M. S., Lee, C. W., Barr, S., Fuchs, S. and Epstein, S. E., Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms, Circ Res 2004;94:678-685.
    • (2004) Circ Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Lee, C.W.4    Barr, S.5    Fuchs, S.6    Epstein, S.E.7
  • 53
    • 0037389156 scopus 로고    scopus 로고
    • An interleukin-6 family cytokine, upregulates matrix metalloproteinase-9 through the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cultured smooth muscle cells
    • Nagata, T., Kai, H., Shibata, R., Koga, M., Yoshimura, A. and Imaizumi, T., Oncostatin M, an interleukin-6 family cytokine, upregulates matrix metalloproteinase-9 through the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cultured smooth muscle cells, Arterioscler Thromb Vasc Biol 2003;23:588-593.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 588-593
    • Nagata, T.1    Kai, H.2    Shibata, R.3    Koga, M.4    Yoshimura, A.5    Imaizumi, T.6    Oncostatin, M.7


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