메뉴 건너뛰기




Volumn 29, Issue 3, 2012, Pages 435-439

Icariin stimulates MC3T3-E1 cell proliferation and differentiation through up-regulation of bone morphogenetic protein-2

Author keywords

Bone morphogenetic protein 2; Icariin; MC3T3 E1 cells; Osteoporosis

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BONE MORPHOGENETIC PROTEIN 2; ICARIIN;

EID: 84862955883     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.845     Document Type: Article
Times cited : (70)

References (26)
  • 1
    • 33750532096 scopus 로고    scopus 로고
    • Epidemiology of osteoporosis
    • DOI 10.1007/s11926-006-0030-6
    • Samelson EJ and Hannan MT: Epidemiology of osteoporosis. Curr Rheumatol Rep 8: 76-83, 2006. (Pubitemid 44659365)
    • (2006) Current Rheumatology Reports , vol.8 , Issue.1 , pp. 76-83
    • Samelson, E.J.1    Hannan, M.T.2
  • 2
    • 31444443689 scopus 로고    scopus 로고
    • Epidemiology, etiology, and diagnosis of osteoporosis
    • Lane NE: Epidemiology, etiology, and diagnosis of osteoporosis. Am J Obstet Gynecol 194 (Suppl 2): S3-S11, 2006.
    • (2006) Am J Obstet Gynecol , vol.194 , Issue.SUPPL. 2
    • Lane, N.E.1
  • 3
    • 70149111015 scopus 로고    scopus 로고
    • The role of mediator mechanisms in inflammation immunopathogenesis in cardiovascular diseases and osteoporosis
    • In Russian
    • Tsurko VV, Leonenko IL, Egorov IV and Krasnoselsky MY: The role of mediator mechanisms in inflammation immunopathogenesis in cardiovascular diseases and osteoporosis. Ter Arkh 81: 92-96, 2009 (In Russian).
    • (2009) Ter Arkh , vol.81 , pp. 92-96
    • Tsurko, V.V.1    Leonenko, I.L.2    Egorov, I.V.3    Krasnoselsky, M.Y.4
  • 4
    • 77949905454 scopus 로고    scopus 로고
    • Quantifying the influence of bone density and thickness on resonance frequency analysis: An in vitro study of biomechanical test materials
    • Bardyn T, Gedet P, Hallermann W and Buchler P: Quantifying the influence of bone density and thickness on resonance frequency analysis: an in vitro study of biomechanical test materials. Int J Oral Maxillofac Implants 24: 1006-1014, 2009.
    • (2009) Int J Oral Maxillofac Implants , vol.24 , pp. 1006-1014
    • Bardyn, T.1    Gedet, P.2    Hallermann, W.3    Buchler, P.4
  • 6
    • 34548577294 scopus 로고    scopus 로고
    • Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: A 24-month randomized, double-blind and placebo-controlled trial
    • DOI 10.1359/jbmr.070405
    • Zhang G, Qin L and Shi Y: Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial. J Bone Miner Res 22: 1072-1079, 2007. (Pubitemid 351343696)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.7 , pp. 1072-1079
    • Zhang, G.1    Qin, L.2    Shi, Y.3
  • 7
    • 67949098855 scopus 로고    scopus 로고
    • Epimedium-derived flavonoids promote osteoblastogenesis and suppress adipogenesis in bone marrow stromal cells while exerting an anabolic effect on osteoporotic bone
    • Peng S, Zhang G, He Y, et al: Epimedium-derived flavonoids promote osteoblastogenesis and suppress adipogenesis in bone marrow stromal cells while exerting an anabolic effect on osteoporotic bone. Bone 45: 534-544, 2009.
    • (2009) Bone , vol.45 , pp. 534-544
    • Peng, S.1    Zhang, G.2    He, Y.3
  • 8
    • 29244441174 scopus 로고    scopus 로고
    • Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells
    • Chen KM, Ge BF, Ma HP, Liu XY, Bai MH and Wang Y: Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells. Pharmazie 60: 939-942, 2005. (Pubitemid 41820762)
    • (2005) Pharmazie , vol.60 , Issue.12 , pp. 939-942
    • Chen, K.M.1    Ge, B.F.2    Ma, H.P.3    Liu, X.Y.4    Bai, M.H.5    Wang, Y.6
  • 9
    • 40849100000 scopus 로고    scopus 로고
    • Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner
    • Zhao J, Ohba S, Shinkai M, Chung UI and Nagamune T: Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner. Biochem Biophys Res Commun 369: 444-448, 2008.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 444-448
    • Zhao, J.1    Ohba, S.2    Shinkai, M.3    Chung, U.I.4    Nagamune, T.5
  • 10
    • 33847080418 scopus 로고    scopus 로고
    • Icariine stimulates proliferation and differentiation of human osteoblasts by increasing production of bone morphogenetic protein 2
    • Engl
    • Yin XX, Chen ZQ, Liu ZJ, Ma QJ and Dang GT: Icariine stimulates proliferation and differentiation of human osteoblasts by increasing production of bone morphogenetic protein 2. Chin Med J (Engl) 120: 204-210, 2007.
    • (2007) Chin Med J , vol.120 , pp. 204-210
    • Yin, X.X.1    Chen, Z.Q.2    Liu, Z.J.3    Ma, Q.J.4    Dang, G.T.5
  • 11
    • 77950021664 scopus 로고    scopus 로고
    • Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression
    • Hsieh TP, Sheu SY, Sun JS, Chen MH and Liu MH: Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression. Phytomedicine 17: 414-423, 2010.
    • (2010) Phytomedicine , vol.17 , pp. 414-423
    • Hsieh, T.P.1    Sheu, S.Y.2    Sun, J.S.3    Chen, M.H.4    Liu, M.H.5
  • 14
    • 77955733196 scopus 로고    scopus 로고
    • Relationship between the serum CA-125 level and bone mineral density in healthy pre- and post-menopausal women
    • Ahn KH, Park HT, Kim T, et al: Relationship between the serum CA-125 level and bone mineral density in healthy pre- and post-menopausal women. Aust NZ J Obstet Gynaecol 50: 371-377, 2010.
    • (2010) Aust NZ J Obstet Gynaecol , vol.50 , pp. 371-377
    • Ahn, K.H.1    Park, H.T.2    Kim, T.3
  • 15
    • 70749117846 scopus 로고    scopus 로고
    • The effect of past use of oral contraceptive on bone mineral density, bone biochemical markers and muscle strength in healthy pre and post menopausal women
    • Allali F, El Mansouri L, Abourazzak F, et al: The effect of past use of oral contraceptive on bone mineral density, bone biochemical markers and muscle strength in healthy pre and post menopausal women. BMC Womens Health 9: 31, 2009.
    • (2009) BMC Womens Health , vol.9 , pp. 31
    • Allali, F.1    El Mansouri, L.2    Abourazzak, F.3
  • 16
    • 77954165040 scopus 로고    scopus 로고
    • Osteoporosis: Social and economic impact
    • Compston J: Osteoporosis: social and economic impact. Radiol Clin North Am 48: 477-482, 2010.
    • (2010) Radiol Clin North Am , vol.48 , pp. 477-482
    • Compston, J.1
  • 17
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • DOI 10.1016/S1534-5807(02)00157-0
    • Karsenty G and Wagner EF: Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2: 389-406, 2002. (Pubitemid 34436569)
    • (2002) Developmental Cell , vol.2 , Issue.4 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 18
    • 33744772589 scopus 로고    scopus 로고
    • Function of BMPs and BMP antagonists in adult bone
    • Abe E: Function of BMPs and BMP antagonists in adult bone. Ann NY Acad Sci 1068: 41-53, 2006.
    • (2006) Ann NY Acad Sci , vol.1068 , pp. 41-53
    • Abe, E.1
  • 19
    • 59149096379 scopus 로고    scopus 로고
    • BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
    • Kamiya N, Ye L, Kobayashi T, et al: BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development 135: 3801-3811, 2008.
    • (2008) Development , vol.135 , pp. 3801-3811
    • Kamiya, N.1    Ye, L.2    Kobayashi, T.3
  • 20
    • 0037673933 scopus 로고    scopus 로고
    • Control of osteoblast function and regulation of bone mass
    • DOI 10.1038/nature01660
    • Harada S and Rodan GA: Control of osteoblast function and regulation of bone mass. Nature 423: 349-355, 2003. (Pubitemid 40852710)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 349-355
    • Harada, S.-I.1    Rodan, G.A.2
  • 22
    • 0037215657 scopus 로고    scopus 로고
    • Induction of human osteoprogenitor chemotaxis, proliferation, differentiation, and bone formation by osteoblast stimulating factor-1/pleiotrophin: Osteoconductive biomimetic scaffolds for tissue engineering
    • DOI 10.1359/jbmr.2003.18.1.47
    • Yang X, Tare RS, Partridge KA, et al: Induction of human osteoprogenitor chemotaxis, proliferation, differentiation, and bone formation by osteoblast stimulating factor-1/pleiotrophin: osteoconductive biomimetic scaffolds for tissue engineering. J Bone Miner Res 18: 47-57, 2003. (Pubitemid 36008339)
    • (2003) Journal of Bone and Mineral Research , vol.18 , Issue.1 , pp. 47-57
    • Yang, X.1    Tare, R.S.2    Partridge, K.A.3    Roach, H.I.4    Clarke, N.M.P.5    Howdle, S.M.6    Shakesheff, K.M.7    Oreffo, R.O.C.8
  • 24
    • 33845918633 scopus 로고    scopus 로고
    • Osteogenic differentiation of human mesenchymal stem cells in collagen matrices: Effect of uniaxial cyclic tensile strain on bone morphogenetic protein (BMP-2) mRNA expression
    • DOI 10.1089/ten.2006.12.3459
    • Sumanasinghe RD, Bernacki SH and Loboa EG: Osteogenic differentiation of human mesenchymal stem cells in collagen matrices: effect of uniaxial cyclic tensile strain on bone morphogenetic protein (BMP-2) mRNA expression. Tissue Eng 12: 3459-3465, 2006. (Pubitemid 46037169)
    • (2006) Tissue Engineering , vol.12 , Issue.12 , pp. 3459-3465
    • Sumanasinghe, R.D.1    Bernacki, S.H.2    Loboa, E.G.3
  • 25
    • 0026769957 scopus 로고
    • Regulation of fracture repair by growth factors
    • Bolander ME: Regulation of fracture repair by growth factors. Proc Soc Exp Biol Med 200: 165-170, 1992.
    • (1992) Proc Soc Exp Biol Med , vol.200 , pp. 165-170
    • Bolander, M.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.