Efficacy of synthetic peptides RP-1 and AA-RP-1 against Leishmania species in vitro and in vivo

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 2, 2012, Pages 658-665

  Erfe, Marie Crisel B ^a   David, Consuelo V ^a,b,c   Huang, Cher ^a   Lu, Victoria ^a   Maretti Mira, Ana Claudia ^a,d   Haskell, Jacquelyn ^a   Bruhn, Kevin W ^a,e   Yeaman, Michael R ^a,e   Craft, Noah ^a,e  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d INSTITUTO OSWALDO CRUZ   (Brazil)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICROBICIDE; SYNTHETIC PEPTIDE; SYNTHETIC PEPTIDE AA RP 1; SYNTHETIC PEPTIDE RP 1; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG EXPOSURE; FEMALE; GROWTH INHIBITION; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIA; LEISHMANIASIS; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PARASITE VIABILITY; PRIORITY JOURNAL; PROMASTIGOTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; ANTIPROTOZOAL AGENTS; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LEISHMANIA; LEISHMANIASIS; LEISHMANIASIS, VISCERAL; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PARASITIC SENSITIVITY TESTS; PEPTIDES; PLATELET FACTOR 4; TREATMENT OUTCOME;

EID: 84862943232     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.05349-11     Document Type: Article

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