Developmental changes in the expression of Leishmania chagasi gp63 and heat shock proteins in a human macrophage cell line

Infection and Immunity

Volumn 64, Issue 5, 1996, Pages 1810-1818

  Streit, Judy A ^a,b   Donelson, John E ^a,c   Agey, Michael W ^a,c   Wilson, Mary E ^a,b,d  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; GLYCOPROTEIN GP 63; HEAT SHOCK PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; GENE EXPRESSION REGULATION; HEAT SHOCK; HUMAN; HUMAN CELL; LEISHMANIA; LEISHMANIA CHAGASI; MACROPHAGE FUNCTION; PARASITE IMMUNITY; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; SEQUENCE ANALYSIS;

EID: 0029969609     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.5.1810-1818.1996     Document Type: Article

References (58)

1. Alfieri, S. C., E. M. F. Pral, E. Shaw, C. Ramazeilles, and M. Rabinovitch. 1991. Leishmania amazonensis: specific labeling of amastigote cysteine proteinases by radioiodinated N-benzyloxycarbonyl-tyrosyl-alanyl diazomethane. Exp. Parasitol. 73:424-432.
2. Bates, P. A. 1993. Characterization of developmentally-regulated nucleases in promastigotes and amastigotes of Leishmania mexicana. FEMS Microbiol. Lett. 107:53-58.
3. Bates, P. A. 1993. Axenic culture of Leishmania amastigotes. Parasitol. Today 9:143-146.
4. Bates, P. A. 1994. Complete developmental cycle of Leishmania mexicana in axenic culture. Parasitology 108:1-9.
5. Bordier, C. 1987. The promastigote surface protease of Leishmania. Parasitol. Today 3:151-153.
6. Button, L. L., D. G. Russell, H. L. Klein, E. Medina-Acosta, R. E. Karess, and W. R. McMaster. 1989 Genes encoding the major surface glycoprotein in Leishmania are tandemly linked at a single chromosomal locus and are constitutively transcribed Mol. Biochem. Parasitol. 32:271-284.
7. Chang, K.-P. 1980. Human cutaneous Leishmania in a mouse macrophage line: propagation and isolation of intracellular parasites. Science 209:1240-1242.
8. Chang, K.-P., and L. D. Hendricks. 1985 laboratory cultivation and maintenance of Leishmania, p. 214-244 In K.-P. Chang and R. S. Bray (ed.), Leishmaniasis. Elsevier Science Publishing. Inc., New York.
9. m9. Chaudhuri, G., M. Chaudhuri, A. Pan, and K.-P. Chang. 1989. Surface acid proteinase (gp63) of Leishmania mexicana: a metalloenzyme capable of protecting liposome-encapsulated proteins from phagolysosomal degradation by macrophages. J. Biol. Chem. 264:7483-7489.
10. m10. Christman, M. F., R. W. Morgan, F. S. Jacobson, and B. N. Ames. 1985. Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium. Cell 41:753-762.
11. Coulson, R. M. R., and D. F. Smith. 1990. Isolation of genes showing increased or unique expression in the infective promastigotes of Leishmania major. Mol. Biochem. Parasitol. 40:63-76.
12. Craig, E. A., B. D. Gambill, and R. J. Nelson. 1993. Heat shock proteins: molecular chaperones of protein biogenesis. Microbiol. Rev. 57:402-414.
13. Doyle, P. S., J. C. Engel, P. F. P. Pimenta, P. Pinto da Silva, and D. M. Dwyer. 1991. Leishmania donovani: long-term culture of axenic amastigotes at 37°C Exp Parasitol. 73:326-334.
14. Eperon, S., and D. McMahon-Pratt. 1989. Extracellular cultivation and morphological characterization of amastigote-like forms of Leishmania panamensis and L. braziliensis. J. Protozool. 36:502-510.
15. Etges, R., J. Bouvier, and C. Bordier. 1986. The major surface protein of Leishmania promastigotes is anchored in the membrane by a myristic acid-labeled phospholipid EMBO J. 5:597-601.
16. Freeman, M. L., D. R. Spitz, and M. J. Meredith. 1990. Does heat shock enhance oxidative stress? Studies with ferrous and ferric iron Radiat. Res. 124:288-293.
17. m17 Frommel, T. O., L. L. Button, Y. Fujikura, and W. K. McMaster. 1990. The major surface glycoprotein (GP63) is present in both life stages of Leishmama. Mol. Biochem. Parasitol. 38:25-32.
18. 17a. Glaser, T. A., S. J. Wells, T. W. Spithill, J. M. Pettitt, D. C. Humphris, and A. J. Mukkada. 1990 Leishmania major and L donovani: a method for rapid purification of amastigotes. Exp. Parasitol. 71:343-345.
19. Hanekamp, T., and P. J. Langer. 1991. Molecular karyotype and chromosomal localization of genes encoding two major surface glycoproteins, gp63 and gp46/M2, hsp70, and β-tubulin in cloned strains of several Leishmania species. Mol. Biochem. Parasitol. 48:27-38.
20. Hightower, L. E. 1991 Heat shock, stress proteins, chaperones, and proteotoxicity. Cell 66:191-197.
21. Hunter, K. W., C. L. Cook, and E. G. Hayunga. 1984. Leishmanial differentiation in vitro: induction of heat shock proteins. Biochem. Biophys. Res. Commun. 125:755-760.
22. Imlay, J. A., and S. Linn. 1988. DNA damage and oxygen radical toxicity. Science 240:1302-1309.
23. Joshi, M., D. M. Dwyer, and H. L. Nakhasi. 1993. Cloning and characterization of differentially expressed genes from in vitro-grown 'amastigotes' of Leishmania donovani. Mol. Biochem. Parasitol. 58:345-354.
24. m23. Kurtz, S. J., J. Rossi, L. Petko, and S. Lindquist. 1986. An ancient developmental induction: heat-shock proteins induced in sporulation and oogenesis. Science 231:1154-1157.
25. m24. Kweider, M., J.-L. Lemesre, F. Darcy, J.-P. Kusnierz, A. Capron, and F. Santoro. 1987. Infectivity of Leishmania braziliensis promastigotes is dependent on the increasing expression of a 65,000-dalton surface antigen. J. Immunol. 138:299-305.
26. Lawrence, F., and M. Robert-Gero. 1985. Induction of heat shock and stress proteins in promastigotes of three Leishmania species. Proc. Natl. Acad. Sci. USA 82:4414-4417.
27. m26. Lee, M. G.-S., B. L. Atkinson, S. H. Giannini, and L. H. T. Van der Ploeg. 1988. Structure and expression of the hsp 70 gene family of Leishmania major. Nucleic Acids Res 16:9567-9585.
28. Lindquist, S. 1986. The heat-shock response Annu. Rev. Biochem. 55: 1151-1191.
29. Maison, C. M., C. L. Villiers, and M. G. Colomb. 1991. Proteolysis of C3 on U937 cell plasma membranes. J. Immunol. 147:921-926.
30. Medina-Acosta, E., R. E. Karess, and D. G. Russell. 1993 Structurally distinct genes from the surface protease of Leishmania mexicana are developmentally regulated. Mol. Biochem. Parasitol. 57:31-46.
31. Medina-Acosta, E., R. E. Karess, H, Schwartz, and D. G. Russell. 1989. The promastigote surface protease (gp63) of Leishmania is expressed but differentially processed and localized in the amastigote stage. Mol. Biochem. Parasitol. 37:263-274.
32. Neumann, S., E. Ziv, F. Lantner, and I. Schechter. 1993. Regulation of hsp70 gene expression during the life cycle of the parasitic helminth Schistosoma mansoni. Eur. J. Biochem. 212:589-596.
33. Pan, A. A. 1986 Leishmania mexicana pifanoi. analysis of the antigenic relationships between promastigotes and amastigotes by gel diffusion, immunoelectrophoresis, and immunoprecipitation. J. Protozool. 33:192-197.
34. Pearson, R. D., and R. T. Steigbigel. 1980. Mechanism of lethal effect of human serum upon Leishmania donovani. J. Immunol. 125:2195-2201.
35. Pearson, R. D., and M. E. Wilson. 1989. Host defenses against prototypical intracellular protozoans, the Leishmania, p. 31-81. In P D. Walzer and R. M Genta (ed.). Parasitic infections in the compromised host. Marcel Dekker, Inc., New York.
36. m35. Rainey, P. M., T. W. Spithill, D. McMahon-Pratt, and A. A. Pan. 1991. Biochemical and molecular characterization of Leishmania pifanoi amastigotes in continuous axenic culture. Mol. Biochem. Parasitol. 49:111-118.
37. Ramamoorthy, R., J. E. Donelson, K. E. Paetz, M. Maybodi, S. P. Roberts, and M. E. Wilson. 1992 Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form. J. Biol. Chem 267:1888-1895.
38. Rey-Ladino, J. A., and N. E. Reiner. 1993. Expression of 65- and 67-kilodalton heat-regulated proteins and a 70-kilodalton heat shock cognate protein of Leishmania donovani in macrophages. Infect. Immun. 61:3265-3272.
39. Roberts, S. C., K. G. Swihart, M. W. Agey, R. Ramamoorthy, M. E. Wilson, and J. E. Donelson. 1993. Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi. Mol. Biochem Parasitol. 62:157-172
40. Roberts, S. C., M. E. Wilson, and J. E. Donelson. 1995. Developmentally regulated expression of a novel 59-kDa product of the major surface protease (msp or gp63) gene family of Leishmania chagasi J Biol Chem. 270: 8884-8892.
41. Russell, D. G., and H. Wilhelm. 1986. The involvement of the major surface glycoprotein (gp63) of Leishmania promastigotes in attachment to macrophages. J. Immunol 136:2613-2620.
42. Sadick, M. D., and H. V. Raff. 1985. Differences in expression and exposure of promastigote and amastigote membrane molecules in Leishmania tropica. Infect Immun. 47:395-400.
43. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning, a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
44. Sanger, F., S. Nicklen, and A, R. Coulson. 1977 DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
45. Schlesinger, M. J. 1990. Heat shock proteins. J. Biol. Chem. 265:12111-12114.
46. Shapira, M., J. G. McEwen, and C. L. Jaffe. 1988. Temperature effects on molecular processes which lead to stage differentiation in Leishmania. EMBO J. 7:2895-2901.
47. Smejkal, R. M., R. Wolff, and J. G. Olenick. 1988. Leishmania braziliensis panamensis: increased infectivity resulting from heat shock. Exp. Parasitol. 65:1-9.
48. Spitz, D. R., W. C. Dewey, and G. C. Li. 1987. Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblasts. J. Cell. Physiol. 131:364-373.
49. Stierhof, Y.-D., H. Schwarz, B. Menz, D. G. Russell, M. Quinten, and P. Overath. 1991. Monoclonal antibodies to Leishmania mexicana promastigote antigens. II. Cellular localization of antigens in promastigotes and infected macrophages. J. Cell Sci. 99:181-186.
50. Toye, P., and H. Remold. 1989. The Influence of temperature and serum deprivation on the synthesis of heat-shock proteins and alpha and beta tubulin in promastigotes of Leishmania major. Mol. Biochem. Parasitol. 35:1-10.
51. Traub-Cseko, Y. M., M. Duboise, L. K. Boukai, and D. McMahon-Pratt. 1993. Identification of two distinct cysteine proteinase genes of Leishmania pifanoi axenic amastigotes using the polymerase chain reaction. Mol. Biochem. Parasitol. 57:101-116.
52. Van der Ploeg, L. H. T., S. H. Giannini, and C. R. Cantor. 1985. Heat shock genes: regulatory role for differentiation in parasitic protozoa. Science 228: 1443-1446.
53. Webb, J. R., L. L. Button, and W. R. McMaster. 1991. Heterogeneity of the genes encoding the major surface glycoprotein of Leishmania donovani. Mol. Biochem. Parasitol. 48:173-184.
54. White, A. C., and C. Hanham. 1991. Species and stage specificity of Leishmania donovani antigens. J. Parasitol. 77:142-150.
55. Wilson, M. E., K. A. Andersen, and B. E. Britigan. 1994. Response of Leishmania promastigotes to oxidant stress. Infect. Immun. 62:5133-5141.
56. Wilson, M. E., and K. K. Hardin. 1988. The major concanavalin A-binding surface glycoprotein of Leishmania donovani chagasi promastigotes is involved in attachment to human macrophages. J. Immunol. 141:265-272
57. Wilson, M. E., D. J. Innes, A. Sousa, and R. D. Pearson. 1987. Early histopathology of experimental infection with Leishmania donovani in hamsters. J. Parasitol. 73:55-63.
58. Zarley, J. H., B. E. Britigan, and M. E. Wilson. 1991. Hydrogen peroxide mediated toxicity for Leishmania donovani chagasi promastigotes: role of hydroxyl radical and protection by heat shock. J. Clin. Invest. 88:1511-1521.