Lxr deficiency confers increased protection against visceral leishmania infection in mice

PLoS Neglected Tropical Diseases

Volumn 4, Issue 11, 2010, Pages

  Bruhn, Kevin W ^a   Marathe, Chaitra ^b,d   Maretti Mira, Ana Cláudia ^a   Nguyen, Hong ^a   Haskell, Jacquelyn ^a   Tran, Thu Anh ^a   Vanchinathan, Veena ^a   Gaur, Upasna ^c   Wilson, Mary E ^c   Tontonoz, Peter ^b   Craft, Noah ^a  

^a LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d NGM Biopharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1BETA; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; NITRIC OXIDE; ORPHAN NUCLEAR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CONTROLLED STUDY; FEMALE; GENE EXPRESSION REGULATION; IMMUNOMODULATION; IN VITRO STUDY; KNOCKOUT MOUSE; LEISHMANIA CHAGASI; LEISHMANIA INFANTUM; LIVER PARENCHYMA; MACROPHAGE FUNCTION; MALE; MOUSE; NONHUMAN; PROTECTION; PROTEIN DEFICIENCY; SIGNAL TRANSDUCTION; SPLEEN; VISCERAL LEISHMANIASIS; WILD TYPE; ANIMAL; C57BL MOUSE; GENETICS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; LEISHMANIA; MACROPHAGE; MOUSE MUTANT; PARASITOLOGY; PHYSIOLOGY;

ANIMALS; FEMALE; HUMANS; IMMUNITY, INNATE; LEISHMANIA; LEISHMANIASIS, VISCERAL; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORPHAN NUCLEAR RECEPTORS;

EID: 78649777345     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pntd.0000886     Document Type: Article

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