NMR structure of a heterodimeric SAM:SAM complex: Characterization and Manipulation of EphA2 Binding Reveal New Cellular Functions of SHIP2

Structure

Volumn 20, Issue 1, 2012, Pages 41-55

  Lee, Hyeong J ^a   Hota, Prasanta K ^a   Chugha, Preeti ^a   Guo, Hong ^a   Miao, Hui ^a   Zhang, Liqun ^a   Kim, Soon Jeung ^a   Stetzik, Lukas ^a   Wang, Bing Cheng ^a,b,c   Buck, Matthias ^a,b,c  

^a MetroHealth ^*  (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN RECEPTOR A2; EPHRIN RECEPTOR B2; HETERODIMER; MUTANT PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP; PROTEIN VARIANT; SH2 LINKED INOSITOL PHOSPHATASE 2; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; CHEMOTAXIS; COMPLEX FORMATION; CONTROLLED STUDY; ENERGY; HETERONUCLEAR SINGLE QUANTUM COHERENCE; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; STERILE ALPHA MOTIF; STRUCTURE ANALYSIS; THERMODYNAMICS; WILD TYPE;

CELL MOVEMENT; DIMERIZATION; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MULTIPROTEIN COMPLEXES; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPHA2;

EID: 84862908973     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2011.11.013     Document Type: Article

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