Whole-cell SELEX aptamer-functionalised poly(ethyleneglycol)-poly(ε-caprolactone) nanoparticles for enhanced targeted glioblastoma therapy

Biomaterials

Volumn 33, Issue 26, 2012, Pages 6264-6272

  Gao, Huile ^a   Qian, Jun ^a   Yang, Zhi ^a   Pang, Zhiqing ^a   Xi, Zhangjie ^a   Cao, Shijie ^a   Wang, Yuchen ^a   Pan, Shuaiqi ^a   Zhang, Shuang ^a   Wang, Wei ^a   Jiang, Xinguo ^a   Zhang, Qizhi ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Glioblastoma; GMT8 aptamer; Nanoparticles; Targeting delivery system

Indexed keywords

ACTIVE TARGETING; APTAMERS; BRAIN SLICES; CAPROLACTONE; CELL APOPTOSIS; DELIVERY SYSTEMS; FLUORESCENCE IMAGING; GLIOBLASTOMA CELLS; GLIOBLASTOMAS; GROWTH INHIBITION; IN-VITRO; IN-VIVO IMAGING; INTRACELLULAR DRUG DELIVERY; MEDIAN SURVIVAL; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENTS; WHOLE CELL;

CELL DEATH; DIAGNOSIS; DRUG DELIVERY; LIGANDS; MAMMALS; NANOPARTICLES;

TUMORS;

APTAMER; DOCETAXEL; MACROGOL; NANOPARTICLE; POLYCAPROLACTONE;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CANCER; CANCER INHIBITION; CANCER LOCALIZATION; CANCER PROGNOSIS; CANCER SURVIVAL; CONTROLLED STUDY; DNA SEQUENCE; DRUG DELIVERY SYSTEM; DRUG PENETRATION; FLUORESCENCE IMAGING; GLIOBLASTOMA; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT; TUMOR SPHEROID; WHOLE CELL;

ANIMALS; APOPTOSIS; CELLS, CULTURED; GLIOBLASTOMA; MALE; MICE; MICE, INBRED BALB C; NANOPARTICLES; POLYESTERS; POLYETHYLENE GLYCOLS; SELEX APTAMER TECHNIQUE;

MUS;

EID: 84862894295     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.05.020     Document Type: Article

References (54)

1. Siegel R., Ward E., Brawley O., Jemal A. Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011, 61(4):212-236.
2. Guo J., Gao X., Su L., Xia H., Gu G., Pang Z., et al. Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery. Biomaterials 2011, 32(31):8010-8020.
3. Van Meir E.G., Hadjipanayis C.G., Norden A.D., Shu H.K., Wen P.Y., Olson J.J. Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 2010, 60(3):166-193.
4. Lawson H.C., Sampath P., Bohan E., Park M.C., Hussain N., Olivi A., et al. Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience. J Neurooncol 2007, 83(1):61-70.
5. Ren J., Shen S., Wang D., Xi Z., Guo L., Pang Z., et al. The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2. Biomaterials 2012, 33(11):3324-3333.
6. Shangguan D., Li Y., Tang Z., Cao Z.C., Chen H.W., Mallikaratchy P., et al. Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A 2006, 103(32):11838-11843.
7. Bayrac A.T., Sefah K., Parekh P., Bayrac C., Gulbakan B., Oktem H.A., et al. In vitro Selection of DNA aptamers to glioblastoma Multiforme. ACS Chem Neurosci 2011, 2(3):175-181.
8. Gueritte-Voegelein F., Guenard D., Lavelle F., Le Goff M.T., Mangatal L., Potier P. Relationships between the structure of taxol analogues and their antimitotic activity. J Med Chem 1991, 34(3):992-998.
9. Sampath P., Rhines L.D., DiMeco F., Tyler B.M., Park M.C., Brem H. Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma. J Neurooncol 2006, 80(1):9-17.
10. Pang Z., Lu W., Gao H., Hu K., Chen J., Zhang C., et al. Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26. J Control Release 2008, 128(2):120-127.
11. Gao H., Pan S., Yang Z., Cao S., Chen C., Jiang X., et al. A cascade targeting strategy for brain neuroglial cells employing nanoparticles modified with angiopep-2 peptide and EGFP-EGF1 protein. Biomaterials 2011, 32(33):8669-8675.
12. Feng L., Chen Y., Ren J., Qu X. A graphene functionalized electrochemical aptasensor for selective label-free detection of cancer cells. Biomaterials 2011, 32(11):2930-2937.
13. Gao H., Pang Z., Pan S., Cao S., Yang Z., Chen C., et al. Anti-glioma effect and safety of docetaxel-loaded nanoemulsion. Arch Pharm Res 2012, 35(2):333-341.
14. Xu Z., Chen L., Gu W., Gao Y., Lin L., Zhang Z., et al. The performance of docetaxel-loaded solid lipid nanoparticles targeted to hepatocellular carcinoma. Biomaterials 2009, 30(2):226-232.
15. Du J., Lu W.L., Ying X., Liu Y., Du P., Tian W., et al. Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumor-bearing animals. Mol Pharm 2009, 6(3):905-917.
16. Jones-Bolin S., Zhao H., Hunter K., Klein-Szanto A., Ruggeri B. The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice. Mol Cancer Ther 2006, 5(7):1744-1753.
17. Mahmoudi M., Lynch I., Ejtehadi M.R., Monopoli M.P., Bombelli F.B., Laurent S. Protein-nanoparticle interactions: opportunities and challenges. Chem Rev 2011, 111(9):5610-5637.
18. Gao H., Pang Z., Fan L., Hu K., Wu B., Jiang X. Effect of lactoferrin- and transferrin-conjugated polymersomes in brain targeting: in vitro and in vivo evaluations. Acta Pharmacol Sin 2010, 31(2):237-243.
19. Zhan C., Gu B., Xie C., Li J., Liu Y., Lu W. Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect. J Control Release 2010, 143(1):136-142.
20. Agarwal S., Sane R., Oberoi R., Ohlfest J.R., Elmquist W.F. Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain. Expert Rev Mol Med 2011, 13. e17.
21. Pitz M.W., Desai A., Grossman S.A., Blakeley J.O. Tissue concentration of systemically administered antineoplastic agents in human brain tumors. J Neurooncol 2011, 104(3):629-638.
22. Fine R.L., Chen J., Balmaceda C., Bruce J.N., Huang M., Desai M., et al. Randomized study of paclitaxel and tamoxifen deposition into human brain tumors: implications for the treatment of metastatic brain tumors. Clin Cancer Res 2006, 12(19):5770-5776.
23. Zhou S., Schuetz J.D., Bunting K.D., Colapietro A.M., Sampath J., Morris J.J., et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001, 7(9):1028-1034.
24. Doyle L.A., Ross D.D. Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2). Oncogene 2003, 22(47):7340-7358.
25. Demeule M., Shedid D., Beaulieu E., Del M.R., Moghrabi A., Ghosn P.B., et al. Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors. Int J Cancer 2001, 93(1):62-66.
26. Li J., Gu B., Meng Q., Yan Z., Gao H., Chen X., et al. The use of myristic acid as a ligand of polyethylenimine/DNA nanoparticles for targeted gene therapy of glioblastoma. Nanotechnology 2011, 22(43):435101.
27. Pang Z., Feng L., Hua R., Chen J., Gao H., Pan S., et al. Lactoferrin-conjugated biodegradable polymersome holding doxorubicin and tetrandrine for chemotherapy of glioma rats. Mol Pharm 2010, 7(6):1995-2005.
28. Pang Z., Gao H., Yu Y., Guo L., Chen J., Pan S., et al. Enhanced intracellular delivery and chemotherapy for glioma rats by transferrin-conjugated biodegradable polymersomes loaded with Doxorubicin. Bioconjug Chem 2011, 22(6):1171-1180.
29. Pardridge W.M. Vector-mediated drug delivery to the brain. Adv Drug Deliv Rev 1999, 36(2-3):299-321.
30. Tang R., Ji W., Panus D., Palumbo R.N., Wang C. Block copolymer micelles with acid-labile ortho ester side-chains: Synthesis, characterization, and enhanced drug delivery to human glioma cells. J Control Release 2011, 151(1):18-27.
31. Zhan C., Li B., Hu L., Wei X., Feng L., Fu W., et al. Micelle-based brain-targeted drug delivery enabled by a nicotine acetylcholine receptor ligand. Angew Chem Int Ed Engl 2011.
32. Gao X., Wu B., Zhang Q., Chen J., Zhu J., Zhang W., et al. Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration. J Control Release 2007, 121(3):156-167.
33. Han L., Huang R., Li J., Liu S., Huang S., Jiang C. Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer. Biomaterials 2011, 32(4):1242-1252.
34. Kim S.Y., Lee Y.M., Baik D.J., Kang J.S. Toxic characteristics of methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) nanospheres; in vitro and in vivo studies in the normal mice. Biomaterials 2003, 24(1):55-63.
35. Xin H., Jiang X., Gu J., Sha X., Chen L., Law K., et al. Angiopep-conjugated poly(ethylene glycol)-co-poly(epsilon-caprolactone) nanoparticles as dual-targeting drug delivery system for brain glioma. Biomaterials 2011, 32(18):4293-4305.
36. Demeule M., Regina A., Che C., Poirier J., Nguyen T., Gabathuler R., et al. Identification and design of peptides as a new drug delivery system for the brain. J Pharmacol Exp Ther 2008, 324(3):1064-1072.
37. Liu Y., Li J., Shao K., Huang R., Ye L., Lou J., et al. A leptin derived 30-amino-acid peptide modified pegylated poly-L-lysine dendrigraft for brain targeted gene delivery. Biomaterials 2010, 31(19):5246-5257.
38. Pasqualini R., Ruoslahti E. Organ targeting in vivo using phage display peptide libraries. Nature 1996, 380(6572):364-366.
39. Ruoslahti E., Pierschbacher M.D. New perspectives in cell adhesion: RGD and integrins. Science 1987, 238(4826):491-497.
40. Yonenaga N., Kenjo E., Asai T., Tsuruta A., Shimizu K., Dewa T., et al. RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment. J Control Release 2011.
41. Waite C.L., Roth C.M. PAMAM-RGD conjugates enhance siRNA delivery through a multicellular spheroid model of malignant glioma. Bioconjug Chem 2009, 20(10):1908-1916.
42. Tyler M.A., Ulasov I.V., Borovjagin A., Sonabend A.M., Khramtsov A., Han Y., et al. Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus. Mol Cancer Ther 2006, 5(9):2408-2416.
43. Gao H., Qian J., Cao S., Yang Z., Pang Z., Pan S., et al. Precise glioma targeting of and penetration by aptamer and peptide dual-functioned nanoparticles. Biomaterials 2012.
44. Zhao M., Su M., Lin X., Luo Y., He H., Cai C., et al. Evaluation of docetaxel-loaded intravenous lipid emulsion: pharmacokinetics, tissue distribution, antitumor activity, safety and toxicity. Pharm Res 2010, 27(8):1687-1702.
45. Ramaswamy B., Puhalla S. Docetaxel: a tubulin-stabilizing agent approved for the management of several solid tumors. Drugs Today (Barc) 2006, 42(4):265-279.
46. Jain R.K., di Tomaso E., Duda D.G., Loeffler J.S., Sorensen A.G., Batchelor T.T. Angiogenesis in brain tumours. Nat Rev Neurosci 2007, 8(8):610-622.
47. Hofer S., Frei K. Gefitinib concentrations in human glioblastoma tissue. J Neurooncol 2007, 82(2):175-176.
48. Stewart D.J., Leavens M., Maor M., Feun L., Luna M., Bonura J., et al. Human central nervous system distribution of cis-diamminedichloroplatinum and use as a radiosensitizer in malignant brain tumors. Cancer Res 1982, 42(6):2474-2479.
49. Stewart D.J., Lu K., Benjamin R.S., Leavens M.E., Luna M., Yap H.Y., et al. Concentration of vinblastine in human intracerebral tumor and other tissues. J Neurooncol 1983, 1(2):139-144.
50. Stewart D.J., Richard M.T., Hugenholtz H., Dennery J.M., Belanger R., Gerin-Lajoie J., et al. Penetration of VP-16 (etoposide) into human intracerebral and extracerebral tumors. J Neurooncol 1984, 2(2):133-139.
51. Rich J.N., Reardon D.A., Peery T., Dowell J.M., Quinn J.A., Penne K.L., et al. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol 2004, 22(1):133-142.
52. Kobayashi H., Man S., Graham C.H., Kapitain S.J., Teicher B.A., Kerbel R.S. Acquired multicellular-mediated resistance to alkylating agents in cancer. Proc Natl Acad Sci U S A 1993, 90(8):3294-3298.
53. Jain R.K. Vascular and interstitial barriers to delivery of therapeutic agents in tumors. Cancer Metastasis Rev 1990, 9(3):253-266.
54. Sutherland R.M. Cell and environment interactions in tumor microregions: the multicell spheroid model. Science 1988, 240(4849):177-184.