-
1
-
-
33748147285
-
Pharmacokinetic considerations in the treatment of CNS tumours
-
DOI 10.2165/00003088-200645090-00002
-
S Motl Y Zhuang CM Waters CF Stewart 2006 Pharmacokinetic considerations in the treatment of CNS tumours Clin Pharmacokinet 45 871 16928151 10.2165/00003088-200645090-00002 1:CAS:528:DC%2BD28XhtVGisrrI (Pubitemid 44313694)
-
(2006)
Clinical Pharmacokinetics
, vol.45
, Issue.9
, pp. 871-903
-
-
Motl, S.1
Zhuang, Y.2
Waters, C.M.3
Stewart, C.F.4
-
2
-
-
34547645047
-
Modelling of the blood - Brain barrier in drug discovery and development
-
DOI 10.1038/nrd2368, PII NRD2368
-
R Cecchelli V Berezowski S Lundquist, et al. 2007 Modelling of the blood-brain barrier in drug discovery, development Nat Rev Drug Discov 6 650 17667956 10.1038/nrd2368 1:CAS:528:DC%2BD2sXotl2qtLc%3D (Pubitemid 47202487)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.8
, pp. 650-661
-
-
Cecchelli, R.1
Berezowski, V.2
Lundquist, S.3
Culot, M.4
Renftel, M.5
Dehouck, M.-P.6
Fenart, L.7
-
3
-
-
13244271912
-
Prediction of blood-brain barrier permeation in drug discovery from in vivo, in vitro and in silico models
-
DOI 10.1016/j.ddtec.2004.11.014, PII S1740674904000629
-
N Abbott 2004 Prediction of blood-brain barrier permeation in drug discovery from in vivo, in vitro, in silico models Drug Discov Today Technol 1 407 10.1016/j.ddtec.2004.11.014 1:CAS:528:DC%2BD2MXhtlSqs7s%3D (Pubitemid 40186344)
-
(2004)
Drug Discovery Today: Technologies
, vol.1
, Issue.4
, pp. 407-416
-
-
Abbott, N.J.1
-
4
-
-
34250182404
-
Chemotherapy delivery issues in central nervous system malignancy: A reality check
-
DOI 10.1200/JCO.2006.09.9861
-
LL Muldoon C Soussain K Jahnke, et al. 2007 Chemotherapy delivery issues in central nervous system malignancy: a reality check J Clin Oncol 25 2295 17538176 10.1200/JCO.2006.09.9861 1:CAS:528:DC%2BD2sXnsVShu7o%3D (Pubitemid 46954658)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.16
, pp. 2295-2305
-
-
Muldoon, L.L.1
Soussain, C.2
Jahnke, K.3
Johanson, C.4
Siegal, T.5
Smith, Q.R.6
Hall, W.A.7
Hynynen, K.8
Senter, P.D.9
Peereboom, D.M.10
Neuwelt, E.A.11
-
5
-
-
0020826160
-
Distributed model for drug deliver to CSF and brain tissue
-
1:CAS:528:DyaL3sXlsFWksrY%3D
-
J Collins R Dedrick 1983 Distributed model for drug deliver to CSF and brain tissue Am J Physiol Regul Integr Comp Physiol 245 R303 1:CAS:528:DyaL3sXlsFWksrY%3D
-
(1983)
Am J Physiol Regul Integr Comp Physiol
, vol.245
, pp. 303
-
-
Collins, J.1
Dedrick, R.2
-
6
-
-
0036349375
-
Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: Implications of the barriers between blood, brain
-
12162757 10.2165/00003088-200241100-00001
-
E de Lange M Danhof 2002 Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood, brain Clin Pharmacokinet 41 691 12162757 10.2165/00003088-200241100-00001
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 691
-
-
De Lange, E.1
Danhof, M.2
-
7
-
-
12344273726
-
The blood-brain barrier: Bottleneck in brain drug development
-
W Pardridge 2005 The blood-brain barrier: bottleneck in brain drug development NeuroRX J Am Soc Exp NeuroTher 2 3
-
(2005)
NeuroRX J Am Soc Exp NeuroTher
, vol.2
, pp. 3
-
-
Pardridge, W.1
-
8
-
-
46949098349
-
Modulation of P-glycoprotein at the blood-brain barrier: Opportunities to improve central nervous system pharmacotherapy
-
DOI 10.1124/pr.107.07109
-
DS Miller B Bauer AMS Hartz 2008 Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy Pharmacol Rev 60 196 18560012 10.1124/pr.107.07109 1:CAS:528:DC%2BD1MXitlWlsrs%3D (Pubitemid 351962009)
-
(2008)
Pharmacological Reviews
, vol.60
, Issue.2
, pp. 196-209
-
-
Miller, D.S.1
Bauer, B.2
Hartz, A.M.S.3
-
9
-
-
34447313404
-
The role of membrane transporters in drug delivery to brain tumors
-
DOI 10.1016/j.canlet.2006.12.023, PII S0304383506006896
-
A Nies 2007 The role of membrane transporters in drug delivery to brain tumors Cancer Lett 254 11 17275180 10.1016/j.canlet.2006.12.023 1:CAS:528:DC%2BD2sXnvFyls7w%3D (Pubitemid 47058801)
-
(2007)
Cancer Letters
, vol.254
, Issue.1
, pp. 11-29
-
-
Nies, A.T.1
-
10
-
-
33646754516
-
Multidrug resistance-associated proteins: Expression, function in the central nervous system
-
16714484 10.1124/pr.58.2.3 1:CAS:528:DC%2BD28XlvVelsL0%3D
-
S Dallas DS Miller R Bendayan 2006 Multidrug resistance-associated proteins: expression, function in the central nervous system Pharmacol Rev 58 140 16714484 10.1124/pr.58.2.3 1:CAS:528:DC%2BD28XlvVelsL0%3D
-
(2006)
Pharmacol Rev
, vol.58
, pp. 140
-
-
Dallas, S.1
Miller, D.S.2
Bendayan, R.3
-
11
-
-
0037204545
-
Computational approaches to the prediction of the blood-brain distribution
-
DOI 10.1016/S0169-409X(02)00005-4, PII S0169409X02000054
-
U Norinder M Haeberlein 2002 Computational approaches to the prediction of the blood-brain distribution Adv Drug Deliv Rev 54 291 11922949 10.1016/S0169-409X(02)00005-4 1:CAS:528:DC%2BD38Xitlartbg%3D (Pubitemid 34260955)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.3
, pp. 291-313
-
-
Norinder, U.1
Haeberlein, M.2
-
12
-
-
2942538155
-
Modelling blood-brain barrier partitioning using Bayesian neural nets
-
DOI 10.1016/j.jmgm.2004.03.010, PII S1093326304000257, Bioactive Discovery in the New Millennium
-
D Winkler F Burden 2004 Modelling blood-brain barrier partitioning using Bayesian neural nets J Mol Graph Model 22 499 15182809 10.1016/j.jmgm.2004.03. 010 1:CAS:528:DC%2BD2cXkslWrsb8%3D (Pubitemid 38746575)
-
(2004)
Journal of Molecular Graphics and Modelling
, vol.22
, Issue.6
, pp. 499-505
-
-
Winkler, D.A.1
Burden, F.R.2
-
13
-
-
0029938236
-
Predicting blood-brain transport of drugs: A computational approach
-
Basak S, Gute B, Drewes L (1996) Predicting blood-brain transport of drugs: a computational approach. Pharm Res 13
-
(1996)
Pharm Res
, pp. 13
-
-
Basak, S.1
Gute, B.2
Drewes, L.3
-
14
-
-
0141958109
-
In silico prediction of blood-brain barrier permeation
-
DOI 10.1016/S1359-6446(03)02827-7, PII S1359644603028277
-
DE Clark 2003 In silico prediction of blood-brain barrier permeation Drug Discov Today 8 927 14554156 10.1016/S1359-6446(03)02827-7 1:CAS:528: DC%2BD3sXnvFSiu70%3D (Pubitemid 37230012)
-
(2003)
Drug Discovery Today
, vol.8
, Issue.20
, pp. 927-933
-
-
Clark, D.E.1
-
15
-
-
70350502604
-
Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors
-
Sarin H (2009) Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors. J Transl Med 7
-
(2009)
J Transl Med
, pp. 7
-
-
Sarin, H.1
-
16
-
-
0344963331
-
Brain tumors and the blood-brain barrier
-
Groothuis D, Vick N (1982) Brain tumors and the blood-brain barrier. Trends Neurosci 5
-
(1982)
Trends Neurosci
, pp. 5
-
-
Groothuis, D.1
Vick, N.2
-
17
-
-
33845991496
-
Contrast-enhanced magnetic resonance imaging of central nervous system tumors: Agents, mechanisms, and applications
-
Essig M, Weber M, Von Tengg-Kobligk H, et al (2006) Contrast-enhanced magnetic resonance imaging of central nervous system tumors: agents, mechanisms, and applications. Top Magn Reson Imaging 17
-
(2006)
Top Magn Reson Imaging
, pp. 17
-
-
Essig, M.1
Weber, M.2
Von Tengg-Kobligk, H.3
-
18
-
-
57049117489
-
Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: A microdialysis study
-
18787762 10.1007/s11060-008-9678-2 1:CAS:528:DC%2BD1MXjvFyluw%3D%3D
-
JO Blakeley J Olson SA Grossman, et al. 2009 Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study J Neurooncol 91 51 18787762 10.1007/s11060-008-9678-2 1:CAS:528:DC%2BD1MXjvFyluw%3D%3D
-
(2009)
J Neurooncol
, vol.91
, pp. 51
-
-
Blakeley, J.O.1
Olson, J.2
Grossman, S.A.3
-
19
-
-
0035878997
-
Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470
-
11454697 1:CAS:528:DC%2BD3MXlsVChsLk%3D
-
J Ma S Pulfer S Li, et al. 2001 Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470 Cancer Res 61 5491 11454697 1:CAS:528:DC%2BD3MXlsVChsLk%3D
-
(2001)
Cancer Res
, vol.61
, pp. 5491
-
-
Ma, J.1
Pulfer, S.2
Li, S.3
-
20
-
-
38349135709
-
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization
-
18187807 10.1158/1535-7163.MCT-07-0552 1:CAS:528:DC%2BD1cXmsVynsg%3D%3D
-
A Claes P Wesseling J Jeuken, et al. 2008 Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization Mol Cancer Ther 7 71 18187807 10.1158/1535-7163.MCT-07-0552 1:CAS:528: DC%2BD1cXmsVynsg%3D%3D
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 71
-
-
Claes, A.1
Wesseling, P.2
Jeuken, J.3
-
21
-
-
12344322943
-
How to measure drug transport across the blood-brain-barrier
-
U Bickel 2005 How to measure drug transport across the blood-brain-barrier NeuroRX J Am Soc Exp NeuroTher 2 15
-
(2005)
NeuroRX J Am Soc Exp NeuroTher
, vol.2
, pp. 15
-
-
Bickel, U.1
-
22
-
-
60749134708
-
Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
-
19094226 10.1186/1479-5876-6-80
-
H Sarin A Kanevsky H Wu, et al. 2008 Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells J Transl Med 6 80 19094226 10.1186/1479-5876-6-80
-
(2008)
J Transl Med
, vol.6
, pp. 80
-
-
Sarin, H.1
Kanevsky, A.2
Wu, H.3
-
23
-
-
70449595570
-
Measurement of the pharmacokinetics, pharmacodynamics of neuroactive compounds
-
19818851 10.1016/j.nbd.2009.09.025
-
M Alavijeh A Palmer 2009 Measurement of the pharmacokinetics, pharmacodynamics of neuroactive compounds Neurobiol Dis 37 38 19818851 10.1016/j.nbd.2009.09.025
-
(2009)
Neurobiol Dis
, vol.37
, pp. 38
-
-
Alavijeh, M.1
Palmer, A.2
-
24
-
-
33644813608
-
In vivo microdialysis for PK and PD studies of anticancer drugs
-
DOI 10.1208/aapsj070366
-
Q Zhou J Gallo 2005 In vivo microdialysis for PK, PD studies of anticancer drugs AAPS J 7 E659 16353942 10.1208/aapsj070366 1:CAS:528: DC%2BD2MXhtlSrtbfN (Pubitemid 41631728)
-
(2005)
AAPS Journal
, vol.7
, Issue.3
, pp. 66
-
-
Zhou, Q.1
Gallo, J.M.2
-
25
-
-
49649121238
-
Drug delivery to brain tumors
-
18541119 10.1007/s11910-008-0036-8 1:CAS:528:DC%2BD1cXhtVeisLbJ
-
J Blakeley 2008 Drug delivery to brain tumors Curr Neurol Neurosci Rep 8 235 18541119 10.1007/s11910-008-0036-8 1:CAS:528:DC%2BD1cXhtVeisLbJ
-
(2008)
Curr Neurol Neurosci Rep
, vol.8
, pp. 235
-
-
Blakeley, J.1
-
26
-
-
72549116837
-
The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: Potential implications for the current approach to chemoradiation
-
19861433 10.1158/1078-0432.CCR-09-1349 1:CAS:528:DC%2BD1MXhtl2ktLfE
-
J Portnow B Badie M Chen, et al. 2009 The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation Clin Cancer Res 15 7092 19861433 10.1158/1078-0432.CCR-09-1349 1:CAS:528:DC%2BD1MXhtl2ktLfE
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7092
-
-
Portnow, J.1
Badie, B.2
Chen, M.3
-
27
-
-
0028111593
-
Clinical pharmacokinetics of carboplatin, MCNU. Gan to kagaku ryoho
-
1:STN:280:DyaK2czgsVantg%3D%3D
-
C Shinohara K Matsumoto M Kuriyama, et al. 1994 Clinical pharmacokinetics of carboplatin, MCNU. Gan to kagaku ryoho Cancer Chemother 21 1163 1:STN:280:DyaK2czgsVantg%3D%3D
-
(1994)
Cancer Chemother
, vol.21
, pp. 1163
-
-
Shinohara, C.1
Matsumoto, K.2
Kuriyama, M.3
-
28
-
-
0032968505
-
Platinum distribution in malignant glioma following intraoperative intravenous infusion of carboplatin
-
DOI 10.1080/02688699943871
-
IR Whittle G Malcolm DI Jodrell M Reid 1999 Platinum distribution in malignant glioma following intraoperative intravenous infusion of carboplatin Br J Neurosurg 13 132 10616580 10.1080/02688699943871 1:STN:280: DC%2BD3c%2Fotl2msQ%3D%3D (Pubitemid 29240415)
-
(1999)
British Journal of Neurosurgery
, vol.13
, Issue.2
, pp. 132-137
-
-
Whittle, I.R.1
Malcolm, G.2
Jodrell, D.I.3
Reid, M.4
-
29
-
-
52949101190
-
Tumor tissue delivery of celingitide after intravenous administration to patients with recurrent glioblastoma (GBM): Preliminary data from NABTC protocol 03-02
-
M Gilbert 2007 Tumor tissue delivery of celingitide after intravenous administration to patients with recurrent glioblastoma (GBM): preliminary data from NABTC protocol 03-02 Neuro-oncol 9 525
-
(2007)
Neuro-oncol
, vol.9
, pp. 525
-
-
Gilbert, M.1
-
30
-
-
0027272293
-
Cis-diamminedichloroplatinum (CDDP) therapy for brain metastasis of lung cancer. I. Distribution within the central nervous system after intravenous, intracarotid infusion
-
8410144 10.1007/BF01324836 1:STN:280:DyaK2c%2FhsFansA%3D%3D
-
H Nakagawa T Fujita S Izumoto, et al. 1993 Cis-diamminedichloroplatinum (CDDP) therapy for brain metastasis of lung cancer. I. Distribution within the central nervous system after intravenous, intracarotid infusion J Neurooncol 16 61 8410144 10.1007/BF01324836 1:STN:280:DyaK2c%2FhsFansA%3D%3D
-
(1993)
J Neurooncol
, vol.16
, pp. 61
-
-
Nakagawa, H.1
Fujita, T.2
Izumoto, S.3
-
31
-
-
0034764188
-
High concentration of Daunorubicin and Daunorubicinol in human malignant astrocytomas after systemic administration of liposomal Daunorubicin
-
Albrecht KW, Hamer PCdW, Leenstra S, et al (2001) High concentration of Daunorubicin and Daunorubicinol in human malignant astrocytomas after systemic administration of liposomal Daunorubicin. Journal of Neuro-Oncology 53
-
(2001)
Journal of Neuro-Oncology
, pp. 53
-
-
Albrecht, K.W.1
Hamer, P.C.D.W.2
Leenstra, S.3
-
32
-
-
0032988632
-
Distribution of daunorubicin and daunorubicinol in human glioma tumors after administration of liposomal daunorubicin
-
DOI 10.1007/s002800050964
-
M Zucchetti A Boiardi A Silvani, et al. 1999 Distribution of daunorubicin, daunorubicinol in human glioma tumors after administration of liposomal daunorubicin Cancer Chemother Pharmacol 44 173 10412954 10.1007/s002800050964 1:CAS:528:DyaK1MXktF2ktr4%3D (Pubitemid 29297066)
-
(1999)
Cancer Chemotherapy and Pharmacology
, vol.44
, Issue.2
, pp. 173-176
-
-
Zucchetti, M.1
Boiardi, A.2
Silvani, A.3
Parisi, I.4
Piccolrovazzi, S.5
D'Incalci, M.6
-
33
-
-
75749122223
-
A phase II trial of erlotinib in patients with recurrent malignant gliomas, nonprogressive glioblastoma multiforme postradiation therapy
-
20150372 1:CAS:528:DC%2BC3cXjvFCnt7Y%3D
-
JJ Raizer L Abrey AB Lassman, et al. 2010 A phase II trial of erlotinib in patients with recurrent malignant gliomas, nonprogressive glioblastoma multiforme postradiation therapy Neuro Oncol 12 95 20150372 1:CAS:528: DC%2BC3cXjvFCnt7Y%3D
-
(2010)
Neuro Oncol
, vol.12
, pp. 95
-
-
Raizer, J.J.1
Abrey, L.2
Lassman, A.B.3
-
34
-
-
0027417973
-
Uptake, retention of estramustine, the presence of estratmustine binding protein in malignant brain tumours in humans
-
8431366 10.1038/bjc.1993.65 1:CAS:528:DyaK3sXhvVaktrs%3D
-
AT Bergenheim PO Gunnarsson K Edman, et al. 1993 Uptake, retention of estramustine, the presence of estratmustine binding protein in malignant brain tumours in humans Br J Cancer 67 358 8431366 10.1038/bjc.1993.65 1:CAS:528:DyaK3sXhvVaktrs%3D
-
(1993)
Br J Cancer
, vol.67
, pp. 358
-
-
Bergenheim, A.T.1
Gunnarsson, P.O.2
Edman, K.3
-
35
-
-
0026025222
-
Concentrations of VP16, VM26 in human brain tumors
-
2009235 1:STN:280:DyaK3M7ot1KmtA%3D%3D
-
M Zucchetti C Rossi R Knerich, et al. 1991 Concentrations of VP16, VM26 in human brain tumors Ann Oncol 2 63 2009235 1:STN:280:DyaK3M7ot1KmtA%3D%3D
-
(1991)
Ann Oncol
, vol.2
, pp. 63
-
-
Zucchetti, M.1
Rossi, C.2
Knerich, R.3
-
36
-
-
0026545228
-
Penetration of etoposide into human malignant brain tumors after intravenous, oral administration
-
1312906 10.1007/BF00686001 1:STN:280:DyaK383gtVGmtw%3D%3D
-
K Kiya T Uozumi H Ogasawara, et al. 1992 Penetration of etoposide into human malignant brain tumors after intravenous, oral administration Cancer Chemother Pharmacol 29 339 1312906 10.1007/BF00686001 1:STN:280: DyaK383gtVGmtw%3D%3D
-
(1992)
Cancer Chemother Pharmacol
, vol.29
, pp. 339
-
-
Kiya, K.1
Uozumi, T.2
Ogasawara, H.3
-
37
-
-
0021148075
-
Penetration of VP-16 (etoposide) into human intracerebral, extracerebral tumors
-
6481426 1:STN:280:DyaL2M%2FgvVymtg%3D%3D
-
DJ Stewart MT Richard H Hugenholtz, et al. 1984 Penetration of VP-16 (etoposide) into human intracerebral, extracerebral tumors J Neurooncol 2 133 6481426 1:STN:280:DyaL2M%2FgvVymtg%3D%3D
-
(1984)
J Neurooncol
, vol.2
, pp. 133
-
-
Stewart, D.J.1
Richard, M.T.2
Hugenholtz, H.3
-
38
-
-
33947256848
-
Gefitinib concentrations in human glioblastoma tissue
-
DOI 10.1007/s11060-006-9257-3
-
S Hofer K Frei 2007 Gefitinib concentrations in human glioblastoma tissue J Neurooncol 82 175 17008949 10.1007/s11060-006-9257-3 (Pubitemid 46431861)
-
(2007)
Journal of Neuro-Oncology
, vol.82
, Issue.2
, pp. 175-176
-
-
Hofer, S.1
Frei, K.2
-
39
-
-
0032743206
-
Penetration of idarubicin into malignant brain tumor tissue
-
DOI 10.1023/A:1006335517191
-
W Boogerd IS Tjahja MMvd Sandt JH Beijnen 1999 Penetration of idarubicin into malignant brain tumor tissue J Neurooncol 44 65 10582671 10.1023/A:1006335517191 1:STN:280:DC%2BD3c%2FkslCqtA%3D%3D (Pubitemid 29515652)
-
(1999)
Journal of Neuro-Oncology
, vol.44
, Issue.1
, pp. 65-69
-
-
Boogerd, W.1
Tjahja, I.S.2
Van De Sandt, M.M.3
Beijnen, J.H.4
-
40
-
-
77950461290
-
Intratumoral concentrations of imatinib after oral administration in patients with glioblastoma multiforme
-
10.1007/s11060-009-0008-0
-
M Holdoff J Supko GL Gallia, et al. 2009 Intratumoral concentrations of imatinib after oral administration in patients with glioblastoma multiforme J Neurooncol 97 241 10.1007/s11060-009-0008-0
-
(2009)
J Neurooncol
, vol.97
, pp. 241
-
-
Holdoff, M.1
Supko, J.2
Gallia, G.L.3
-
41
-
-
72049088625
-
Tumor sequestration of lapatinib
-
JG Kuhn 2008 Tumor sequestration of lapatinib Neuro-oncol 10 783
-
(2008)
Neuro-oncol
, vol.10
, pp. 783
-
-
Kuhn, J.G.1
-
42
-
-
0023876927
-
Human central nervous system, plasma pharmacology of mitoxantrone
-
3397768 10.1007/BF00163544 1:STN:280:DyaL1c3os1WqtA%3D%3D
-
RM Green DJ Stewart H Hugenholtz, et al. 1988 Human central nervous system, plasma pharmacology of mitoxantrone J Neurooncol 6 75 3397768 10.1007/BF00163544 1:STN:280:DyaL1c3os1WqtA%3D%3D
-
(1988)
J Neurooncol
, vol.6
, pp. 75
-
-
Green, R.M.1
Stewart, D.J.2
Hugenholtz, H.3
-
43
-
-
0028670256
-
Paclitaxel (TAXOL) concentrations in brain tumor tissue
-
7696168 1:STN:280:DyaK2M3htVWmsA%3D%3D
-
JJ Heimans JB Vermorken JB Wolbers, et al. 1994 Paclitaxel (TAXOL) concentrations in brain tumor tissue Ann Oncol 5 951 7696168 1:STN:280:DyaK2M3htVWmsA%3D%3D
-
(1994)
Ann Oncol
, vol.5
, pp. 951
-
-
Heimans, J.J.1
Vermorken, J.B.2
Wolbers, J.B.3
-
44
-
-
33750293878
-
Randomized study of paclitaxel and tamoxifen deposition into human brain tumors: Implications for the treatment of metastatic brain tumors
-
DOI 10.1158/1078-0432.CCR-05-2356
-
RL Fine J Chen C Balmaceda, et al. 2006 Randomized study of paclitaxel, tamoxifen deposition into human brain tumors: implications for the treatment of metastatic brain tumors Clin Cancer Res 12 5770 17020983 10.1158/1078-0432.CCR- 05-2356 1:CAS:528:DC%2BD28XhtVartbvE (Pubitemid 44629608)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.19
, pp. 5770-5776
-
-
Fine, R.L.1
Chen, J.2
Balmaceda, C.3
Bruce, J.N.4
Huang, M.5
Desai, M.6
Sisti, M.B.7
McKhann, G.M.8
Goodman, R.R.9
Bertino Jr., J.S.10
Nafziger, A.N.11
Fetell, M.R.12
-
45
-
-
0025232735
-
The disposition of TCNU (tauromustine) in human malignant glioma: Phamacokinetic studies, clinical implications
-
2157825 10.3171/jns.1990.72.5.0721 1:STN:280:DyaK3c3hvVaisA%3D%3D
-
IR Whittle JS MacPherson JD Miller JF Smyth 1990 The disposition of TCNU (tauromustine) in human malignant glioma: phamacokinetic studies, clinical implications J Neurosurg 72 721 2157825 10.3171/jns.1990.72.5.0721 1:STN:280:DyaK3c3hvVaisA%3D%3D
-
(1990)
J Neurosurg
, vol.72
, pp. 721
-
-
Whittle, I.R.1
MacPherson, J.S.2
Miller, J.D.3
Smyth, J.F.4
-
46
-
-
37549070324
-
Pharmocokinetic and tumor distribution characteristics of temsirolimus
-
18094423 10.1158/1078-0432.CCR-07-0781 1:CAS:528:DC%2BD2sXhsVCktr3P
-
JG Kuhn SM Chang PY Wen, et al. 2007 Pharmocokinetic and tumor distribution characteristics of temsirolimus Clin Cancer Res 13 7401 18094423 10.1158/1078-0432.CCR-07-0781 1:CAS:528:DC%2BD2sXhsVCktr3P
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7401
-
-
Kuhn, J.G.1
Chang, S.M.2
Wen, P.Y.3
-
47
-
-
0030958676
-
The vascular compartment hampers accurate determination of teniposide penetration into brain tumor tissue
-
DOI 10.1007/s002800050665
-
O van Tellingen W Boogerd WJ Nooijen JH Beijnen 1997 The vascular compartment hampers accurate determination of teniposide penetration into brain tumor tissue Cancer Chemother Pharmacol 40 330 9225951 10.1007/s002800050665 (Pubitemid 27276137)
-
(1997)
Cancer Chemotherapy and Pharmacology
, vol.40
, Issue.4
, pp. 330-334
-
-
Van Tellingen, O.1
Boogerd, W.2
Nooijen, W.J.3
Beijnen, J.H.4
-
48
-
-
0021715519
-
Penetration of teniposide (VM-26) into human intracerebral tumors
-
6530619 1:CAS:528:DyaL2MXhsVakt7s%3D
-
DJ Stewart MT Richard H Hugenholtz, et al. 1984 Penetration of teniposide (VM-26) into human intracerebral tumors J Neurooncol 2 315 6530619 1:CAS:528:DyaL2MXhsVakt7s%3D
-
(1984)
J Neurooncol
, vol.2
, pp. 315
-
-
Stewart, D.J.1
Richard, M.T.2
Hugenholtz, H.3
-
49
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
R Stupp WP Mason MJ Bent, et al. 2005 Radiotherapy plus concomitant, adjuvant temozolomide for glioblastoma N Engl J Med 352 987 15758009 10.1056/NEJMoa043330 1:CAS:528:DC%2BD2MXit1Wksbk%3D (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
50
-
-
34247218483
-
Gefitinib in patients with progressive high-grade gliomas: A multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
-
DOI 10.1038/sj.bjc.6603669, PII 6603669
-
E Franceschi G Cavallo S Lonardi, et al. 2007 Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO) Br J Cancer 96 1047 17353924 10.1038/sj.bjc.6603669 1:CAS:528:DC%2BD2sXjsleksLw%3D (Pubitemid 46608313)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.7
, pp. 1047-1051
-
-
Franceschi, E.1
Cavallo, G.2
Lonardi, S.3
Magrini, E.4
Tosoni, A.5
Grosso, D.6
Scopece, L.7
Blatt, V.8
Urbini, B.9
Pession, A.10
Tallini, G.11
Crino, L.12
Brandes, A.A.13
-
51
-
-
0036632353
-
Changes in blood-brain barrier permeability induced by radiotherapy: Implications for timing of chemotherapy?
-
12066192
-
Mv Vulpen HB Kal MJ Taphoorn SYE Sharouni 2002 Changes in blood-brain barrier permeability induced by radiotherapy: implications for timing of chemotherapy? Oncol Rep 9 683 12066192
-
(2002)
Oncol Rep
, vol.9
, pp. 683
-
-
Mv, V.1
Kal, H.B.2
Taphoorn, M.J.3
Sharouni, S.Y.E.4
-
52
-
-
1042266257
-
Prediction of blood-brain barrier penetration: Are we missing the point?
-
DOI 10.1016/S1359-6446(03)02961-1, PII S1359644603029611
-
I Martin 2004 Prediction of blood-brain barrier penetration: are we missing the point? Drug Discov Today 9 161 14960394 10.1016/S1359-6446(03)02961- 1 (Pubitemid 38199960)
-
(2004)
Drug Discovery Today
, vol.9
, Issue.4
, pp. 161-162
-
-
Martin, I.1
|