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Volumn 1258, Issue 1, 2012, Pages 100-107

Effects of quercetin studied in colonic HT-29/B6 cells and rat intestine in vitro

Author keywords

Barrier function; Claudins; Flavonoid; Tight junction; TNF

Indexed keywords

CELL PROTEIN; CLAUDIN 2; GAMMA INTERFERON; QUERCETIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84862887727     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2012.06609.x     Document Type: Article
Times cited : (42)

References (35)
  • 1
    • 44449100218 scopus 로고    scopus 로고
    • Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells
    • Amasheh, M., S. Schlichter, S. Amasheh, et al 2008. Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells. J. Nutr. 138: 1067-1073.
    • (2008) J. Nutr. , vol.138 , pp. 1067-1073
    • Amasheh, M.1    Schlichter, S.2    Amasheh, S.3
  • 2
    • 65349095529 scopus 로고    scopus 로고
    • Quercetin enhances intestinal barrier function through the assembly of zonula occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells
    • Suzuki, T. & H. Hara 2009. Quercetin enhances intestinal barrier function through the assembly of zonula occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells. J. Nutr. 139: 965-974.
    • (2009) J. Nutr. , vol.139 , pp. 965-974
    • Suzuki, T.1    Hara, H.2
  • 3
    • 0043063961 scopus 로고    scopus 로고
    • Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism
    • Murota, K. & J. Terao 2003. Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism. Arch. Biochem. Biophys. 417: 12-17.
    • (2003) Arch. Biochem. Biophys. , vol.417 , pp. 12-17
    • Murota, K.1    Terao, J.2
  • 4
    • 0037462073 scopus 로고    scopus 로고
    • Absorption and urinary excretion of quercetin, rutin, and alphaG-rutin, a water soluble flavonoid, in rats
    • Shimoi, K., Yoshizumi T. Kido, et al 2003. Absorption and urinary excretion of quercetin, rutin, and alphaG-rutin, a water soluble flavonoid, in rats. J. Agric. Food Chem. 51: 2785-2789.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 2785-2789
    • Shimoi, K.1    Kido, Y.T.2
  • 5
    • 33751391867 scopus 로고
    • Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands
    • Hertog, M.G.L., P.C.H. Hollman & M.B. Katan 1992. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J. Agric. Food Chem. 40: 2379-2383.
    • (1992) J. Agric. Food Chem. , vol.40 , pp. 2379-2383
    • Hertog, M.G.L.1    Hollman, P.C.H.2    Katan, M.B.3
  • 6
    • 0034658374 scopus 로고    scopus 로고
    • Flavonoids, flavones and flavanols-nature, occurrence and dietary burden
    • Hollman, P.C.A. & I.C.W. Arts 2000. Flavonoids, flavones and flavanols-nature, occurrence and dietary burden. J. Sci. Food Agric. 80: 1081-1093.
    • (2000) J. Sci. Food Agric. , vol.80 , pp. 1081-1093
    • Hollman, P.C.A.1    Arts, I.C.W.2
  • 7
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer
    • Middleton, E., C. Kandaswami & T. Theoharides 2000. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer. Pharmacol. Rev. 52: 673-751.
    • (2000) Pharmacol. Rev. , vol.52 , pp. 673-751
    • Middleton, E.1    Kandaswami, C.2    Theoharides, T.3
  • 8
    • 33845995125 scopus 로고    scopus 로고
    • Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
    • Zeissig, S., N. Buergel, D. Guenzel, et al 2007. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 56: 61-72.
    • (2007) Gut , vol.56 , pp. 61-72
    • Zeissig, S.1    Buergel, N.2    Guenzel, D.3
  • 9
    • 0035210487 scopus 로고    scopus 로고
    • Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging
    • Gitter, A.H., F. Wullstein, M. Fromm & J.D. Schulzke 2001. Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging. Gastroenterology 121: 1320-1328.
    • (2001) Gastroenterology , vol.121 , pp. 1320-1328
    • Gitter, A.H.1    Wullstein, F.2    Fromm, M.3    Schulzke, J.D.4
  • 10
    • 0036678630 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease
    • Suenaert, P., V. Bulteel, L. Lemmens, et al 2002. Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease. Am. J. Gastroenterol. 97: 2000-2004.
    • (2002) Am. J. Gastroenterol. , vol.97 , pp. 2000-2004
    • Suenaert, P.1    Bulteel, V.2    Lemmens, L.3
  • 11
    • 78649730159 scopus 로고    scopus 로고
    • TNFalpha-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFkappaB signaling
    • Amasheh, M., A. Fromm, S.M. Krug, et al 2010. TNFalpha-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFkappaB signaling. J. Cell Sci. 123: 4145-4155.
    • (2010) J. Cell Sci. , vol.123 , pp. 4145-4155
    • Amasheh, M.1    Fromm, A.2    Krug, S.M.3
  • 12
    • 0345447585 scopus 로고    scopus 로고
    • Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms
    • Bruewer, M., A. Luegering, T. Kucharzik, et al 2003. Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J. Immunol. 171: 6164-6172.
    • (2003) J. Immunol. , vol.171 , pp. 6164-6172
    • Bruewer, M.1    Luegering, A.2    Kucharzik, T.3
  • 13
    • 27744551342 scopus 로고    scopus 로고
    • Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells
    • Prasad, S., R. Mingrino, K. Kaukinen, et al 2005. Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells. Lab. Invest. 85: 1139-1162.
    • (2005) Lab. Invest. , vol.85 , pp. 1139-1162
    • Prasad, S.1    Mingrino, R.2    Kaukinen, K.3
  • 14
    • 0033818743 scopus 로고    scopus 로고
    • Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis
    • Gitter, A.H., K. Bendfeldt, J.D. Schulzke & M. Fromm 2000. Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis. FASEB J. 14: 1749-1753.
    • (2000) FASEB J. , vol.14 , pp. 1749-1753
    • Gitter, A.H.1    Bendfeldt, K.2    Schulzke, J.D.3    Fromm, M.4
  • 15
    • 80054982785 scopus 로고    scopus 로고
    • The gut as communicator between environment and host: immunological consequences
    • Brandtzaeg, P. 2011. The gut as communicator between environment and host: immunological consequences. Eur. J. Pharmacol. 668(Suppl. 1): S16-S32.
    • (2011) Eur. J. Pharmacol. , vol.668 , Issue.SUPPL. 1
    • Brandtzaeg, P.1
  • 16
    • 33646082016 scopus 로고    scopus 로고
    • Intestinal neuro-epithelial interactions modulate neuronal chemokines production
    • Tixier, E., J.P. Galmiche & M. Neunlist 2006. Intestinal neuro-epithelial interactions modulate neuronal chemokines production. Biochem. Biophys. Res. Commun. 344: 554-561.
    • (2006) Biochem. Biophys. Res. Commun. , vol.344 , pp. 554-561
    • Tixier, E.1    Galmiche, J.P.2    Neunlist, M.3
  • 17
    • 44949109232 scopus 로고    scopus 로고
    • Immune-non immune networks in intestinal inflammation
    • Hausmann, M. & G. Rogler 2008. Immune-non immune networks in intestinal inflammation. Curr. Drug Targets 9: 388-394.
    • (2008) Curr. Drug Targets , vol.9 , pp. 388-394
    • Hausmann, M.1    Rogler, G.2
  • 18
    • 70350648021 scopus 로고    scopus 로고
    • Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: a novel model for studying the pathomechanisms of inflammatory bowel disease cytokines
    • Amasheh, M., I. Grotjohann, S. Amasheh, et al 2009. Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: a novel model for studying the pathomechanisms of inflammatory bowel disease cytokines. Scand. J. Gastroenterol. 44: 1226-1235.
    • (2009) Scand. J. Gastroenterol. , vol.44 , pp. 1226-1235
    • Amasheh, M.1    Grotjohann, I.2    Amasheh, S.3
  • 20
    • 0037115724 scopus 로고    scopus 로고
    • Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
    • Amasheh, S., N. Meiri, A.H. Gitter, et al 2002. Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells. J. Cell Sci. 115: 4969-4976.
    • (2002) J. Cell Sci. , vol.115 , pp. 4969-4976
    • Amasheh, S.1    Meiri, N.2    Gitter, A.H.3
  • 21
    • 7044253578 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-gamma but not by IL-4
    • Watson, J.L., S. Ansari, H. Cameron, et al 2004. Green tea polyphenol (-)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-gamma but not by IL-4. Am. J. Physiol. Gastrointest. Liver Physiol. 287: G954-G961.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.287
    • Watson, J.L.1    Ansari, S.2    Cameron, H.3
  • 22
    • 78650452784 scopus 로고    scopus 로고
    • Kaempferol enhances intestinal barrier function through the cytoskeletal association and expression of tight junction proteins in Caco-2 cells
    • Suzuki, T., S. Tanabe & H. Hara 2011. Kaempferol enhances intestinal barrier function through the cytoskeletal association and expression of tight junction proteins in Caco-2 cells. J. Nutr. 141: 87-94.
    • (2011) J. Nutr. , vol.141 , pp. 87-94
    • Suzuki, T.1    Tanabe, S.2    Hara, H.3
  • 23
    • 0034967963 scopus 로고    scopus 로고
    • Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial tight junctions
    • Atkinson, K.J. & R.K. Rao 2001. Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial tight junctions. Am. J. Physiol. Gastrointest. Liver Physiol. 280: G1280-G1288.
    • (2001) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.280
    • Atkinson, K.J.1    Rao, R.K.2
  • 24
    • 0030636792 scopus 로고    scopus 로고
    • Evidence for altered regulation of IκBα degradation in human colonic epithelial cells
    • Jobin, C., S. Haskill, L. Mayer, et al 1997. Evidence for altered regulation of IκBα degradation in human colonic epithelial cells. J. Immunol. 158: 226-234.
    • (1997) J. Immunol. , vol.158 , pp. 226-234
    • Jobin, C.1    Haskill, S.2    Mayer, L.3
  • 25
    • 1342280570 scopus 로고    scopus 로고
    • TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation
    • Ma, T.Y., G.K. Iwamoto, N.T. Hoa, et al 2004. TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation. Am. J. Physiol. Gastrointest. Liver Physiol. 286: G367-G376.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.286
    • Ma, T.Y.1    Iwamoto, G.K.2    Hoa, N.T.3
  • 26
    • 0000418018 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/6B
    • Schmitz, H., M. Fromm, C.J. Bentzel, et al 1999. Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/6B. J. Cell Sci. 112: 137-146.
    • (1999) J. Cell Sci. , vol.112 , pp. 137-146
    • Schmitz, H.1    Fromm, M.2    Bentzel, C.J.3
  • 27
    • 3042816689 scopus 로고    scopus 로고
    • Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells
    • Wenzel, U., A. Herzog, S. Kuntz & H. Daniel 2004. Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells. Proteomics 4: 2160-2174.
    • (2004) Proteomics , vol.4 , pp. 2160-2174
    • Wenzel, U.1    Herzog, A.2    Kuntz, S.3    Daniel, H.4
  • 28
    • 16644403653 scopus 로고    scopus 로고
    • Flavone inhibition of tumor growth via apoptosis in vitro and in vivo
    • Chen, Y.C., S.C. Shen, J.M. Chow, et al 2004. Flavone inhibition of tumor growth via apoptosis in vitro and in vivo. Int. J. Oncol. 25: 661-70.
    • (2004) Int. J. Oncol. , vol.25 , pp. 661-670
    • Chen, Y.C.1    Shen, S.C.2    Chow, J.M.3
  • 29
    • 1442327911 scopus 로고    scopus 로고
    • Early and late apoptosis events in human transformed and non-transformed colonocytes are independent on intracellular acidification
    • Wenzel, U. & H. Daniel 2004. Early and late apoptosis events in human transformed and non-transformed colonocytes are independent on intracellular acidification. Cell Physiol. Biochem. 14: 65-76.
    • (2004) Cell Physiol. Biochem. , vol.14 , pp. 65-76
    • Wenzel, U.1    Daniel, H.2
  • 30
    • 0035449868 scopus 로고    scopus 로고
    • Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis
    • Bojarski, C., A.H. Gitter, K. Bendfeldt, et al 2001. Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis. J. Physiol. 535: 541-52.
    • (2001) J. Physiol. , vol.535 , pp. 541-552
    • Bojarski, C.1    Gitter, A.H.2    Bendfeldt, K.3
  • 31
    • 10844222740 scopus 로고    scopus 로고
    • The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression
    • Camuesco, D., M. Comalada, M.E. Rodriguez-Cabezas, et al 2004. The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression. Br. J. Pharmacol. 143: 908-918.
    • (2004) Br. J. Pharmacol. , vol.143 , pp. 908-918
    • Camuesco, D.1    Comalada, M.2    Rodriguez-Cabezas, M.E.3
  • 32
    • 14744294057 scopus 로고    scopus 로고
    • In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-κB pathway
    • Comalada, M., D. Camuesco, S. Sierra, et al 2005. In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-κB pathway. Eur. J. Immunol. 35: 584-592.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 584-592
    • Comalada, M.1    Camuesco, D.2    Sierra, S.3
  • 33
    • 0033672942 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells
    • Nusrat, A. 2000. Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells. Am. J. Physiol. Gastrointest. Liver Physiol. 279: G851-G857.
    • (2000) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.279
    • Nusrat, A.1
  • 34
    • 23244455992 scopus 로고    scopus 로고
    • Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution
    • Heller, F., P. Florian, C. Bojarski, et al 2005. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology 129: 550-564.
    • (2005) Gastroenterology , vol.129 , pp. 550-564
    • Heller, F.1    Florian, P.2    Bojarski, C.3
  • 35
    • 0034122209 scopus 로고    scopus 로고
    • Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma
    • Mankertz, J., S. Tavalali, H. Schmitz, et al 2000. Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma. J. Cell Sci. 113: 2085-2090.
    • (2000) J. Cell Sci. , vol.113 , pp. 2085-2090
    • Mankertz, J.1    Tavalali, S.2    Schmitz, H.3


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