Methylphenidate effects on prefrontal functioning during attentional-capture and response inhibition

Biological Psychiatry

Volumn 72, Issue 2, 2012, Pages 142-149

  Pauls, Astrid M ^a   O'Daly, Owen G ^a   Rubia, Katya ^a   Riedel, Wim J ^b   Williams, Steven C R ^a   Mehta, Mitul A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Attentional capture; fMRI; methylphenidate; motor response inhibition; right inferior frontal gyrus; stop signal task

Indexed keywords

ASCORBIC ACID; METHYLPHENIDATE;

ANTERIOR CINGULATE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; INFERIOR FRONTAL GYRUS; INSULA; MALE; MENTAL TASK; NERVE CELL INHIBITION; NERVE CELL NETWORK; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; OCCIPITAL CORTEX; PARIETAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; SUPERIOR FRONTAL GYRUS;

ADULT; ATTENTION; BRAIN MAPPING; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FRONTAL LOBE; HUMANS; INHIBITION (PSYCHOLOGY); MAGNETIC RESONANCE IMAGING; MALE; METHYLPHENIDATE; NEURAL PATHWAYS; OCCIPITAL LOBE; PARIETAL LOBE; PLACEBOS; PREFRONTAL CORTEX; PSYCHOMOTOR PERFORMANCE;

EID: 84862865100     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.03.028     Document Type: Article

References (63)

1. A.F.T. Arnsten Stimulants: Therapeutic actions in ADHD Neuropsychopharmacology 31 2006 2376 2383
2. T.E. Wilens Effects of methylphenidate on the catecholaminergic system in attention-deficit/hyperactivity disorder J Clin Psychopharmacol 28 3 Suppl 2 2008 S46 S53
3. J. Krause SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder Expert Rev Neurother 8 2008 611 625
4. J. Hannestad, J.D. Gallezot, B. Planeta-Wilson, S.F. Lin, W.A. Williams, C.H. van Dyck Clinically relevant doses of methylphenidate significantly occupy norepinephrine transporters in humans in vivo Biol Psychiatry 68 2010 854 860
5. K. Rubia, R. Halari, A.M. Mohammad, E. Taylor, M. Brammer Methylphenidate normalizes frontocingulate underactivation during error processing in attention-deficit/hyperactivity disorder Biol Psychiatry 70 2011 255 262
6. C.M. Dodds, U. Muller, L. Clark, A. van Loon, R. Cools, T.W. Robbins Methylphenidate has differential effects on blood oxygenation level-dependent signal related to cognitive subprocesses of reversal learning J Neurosci 28 2008 5976 5982
7. M.A. Mehta, I.A. Goodyer, B.J. Sahakian Methylphenidate improves working memory and set-shifting in AD/HD: Relationships to baseline memory capacity J Child Psychol Psychiatry 45 2004 293 305
8. K. Rubia, R. Halari, A. Christakou, E. Taylor Impulsiveness as a timing disturbance: Neurocognitive abnormalities in attention-deficit hyperactivity disorder during temporal processes and normalization with methylphenidate Phil Trans Royal Soc B Biol Sci 364 2009 1919 1931
9. C.J. Vaidya, G. Austin, G. Kirkorian, H.W. Ridlehuber, J.E. Desmond, G.H. Glover Selective effects of methylphenidate in attention deficit hyperactivity disorder: A functional magnetic resonance study Proc Natl Acad Sci U S A 95 1998 1494 1499
10. M.A. Mehta, A.M. Owen, B.J. Sahakian, N. Mavaddat, J.D. Pickard, T.W. Robbins Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain J Neurosci 20 2000 RC65
11. K. Rubia, R. Halari, A. Cubillo, A.B. Smith, A.M. Mohammad, M. Brammer Methylphenidate normalizes fronto-striatal underactivation during interference inhibition in medication-naive boys with attention-deficit hyperactivity disorder Neuropsychopharmacology 36 2011 1575 1586
12. A.F. Marquand, S. De Simoni, O.G. O'Daly, S.C.R. Williams, J. Mourao-Miranda, M.A. Mehta Pattern classification of working memory networks reveals differential effects of methylphenidate, atomoxetine, and placebo in healthy volunteers Neuropsychopharmacology 36 2011 1237 1247
13. A.R. Aron, J.H. Dowson, B.J. Sahakian, T.W. Robbins Methylphenidate improves response inhibition in adults with attention-deficit/hyperactivity disorder Biol Psychiatry 54 2003 1465 1468
14. L.S. Nandam, R. Hester, J. Wagner, T.D.R. Cummins, K. Garner, A.J. Dean Methylphenidate but not atomoxetine or citalopram modulates inhibitory control and response time variability Biol Psychiatry 69 2011 902 904
15. C.C.E. Overtoom, E.M. Bekker, M.W. van der Molen, M.N. Verbaten, J.J.S. Kooij, J.K. Buitelaar Methylphenidate restores link between stop-signal sensory impact and successful stopping in adults with attention-deficit/hyperactivity disorder Biol Psychiatry 65 2009 614 619
16. F. Verbruggen, G.D. Logan Models of response inhibition in the stop-signal and stop-change paradigms Neurosci Biobehav Rev 33 2009 647 661
17. A.R. Aron, T.W. Robbins, R.A. Poldrack Inhibition and the right inferior frontal cortex Trends Cogn Sci 8 2004 170 177
18. K. Rubia, A.B. Smith, M.J. Brammer, E. Taylor Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection NeuroImage 20 2003 351 358
19. A.R. Aron, T.E. Behrens, S. Smith, M.J. Frank, R.A. Poldrack Triangulating a cognitive control network using diffusion-weighted magnetic resonance imaging (MRI) and functional MRI J Neurosci 27 2007 3743 3752
20. J. Downar, A.P. Crawley, D.J. Mikulis, K.D. Davis The effect of task relevance on the cortical response to changes in visual and auditory stimuli: An event-related fMRI study Neuroimage 14 2001 1256 1267
21. K. Rubia, Z. Hyde, R. Halari, V. Giampietro, A. Smith Effects of age and sex on developmental neural networks of visual-spatial attention allocation Neuroimage 51 2010 817 827
22. J. Downar, A.P. Crawley, D.J. Mikulis, K.D. Davis A cortical network sensitive to stimulus salience in a neutral behavioral context across multiple sensory modalities J Neurophysiol 87 2002 615 620
23. E. Kirino, A. Belger, P. Goldman-Rakic, G. McCarthy Prefrontal activation evoked by infrequent target and novel stimuli in a visual target detection task: An event-related functional magnetic resonance imaging study J Neurosci 20 2000 6612 6618
24. P. Helenius, M. Laasonen, L. Hokkanen, R. Paetau, M. Niemivirta Impaired engagement of the ventral attentional pathway in ADHD Neuropsychologia 49 2011 1889 1896
25. K. Rubia, R. Halari, A. Cubillo, A.M. Mohammad, M. Brammer, E. Taylor Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naive children with ADHD during a rewarded continuous performance task Neuropharmacology 57 2009 640 652
26. J. Chikazoe, K. Jimura, T. Asari, K.I. Yamashita, H. Morimoto, S. Hirose Functional dissociation in right inferior frontal cortex during performance of Go/No-Go task Cereb Cortex 19 2009 146 152
27. A. Hampshire, S.R. Chamberlain, M.M. Monti, J. Duncan, A.M. Owen The role of the right inferior frontal gyrus: Inhibition and attentional control Neuroimage 50 2010 1313 1319
28. D.J. Sharp, V. Bonnelle, X. De Boissezon, C.F. Beckmann, S.G. James, M.C. Patel Distinct frontal systems for response inhibition, attentional capture, and error processing Proc Natl Acad Sci 107 2010 6106 6111
29. Y. Groen, L.J.M. Mulder, A.A. Wijers, R.B. Minderaa, M. Althaus Methylphenidate improves diminished error and feedback sensitivity in ADHD: An evoked heart rate analysis Biol Psychol 82 2009 45 53
30. L.M. Jonkman, J.J.M. van Melis, C. Kemner, C.R. Markus Methylphenidate improves deficient error evaluation in children with ADHD: An event-related brain potential study Biol Psychol 76 2007 217 229
31. R.C. Kessler, L. Adler, M. Ames, O. Demler, S. Faraone, E.V.A. Hiripi The World Health Organization adult ADHD self-report scale (ASRS): A short screening scale for use in the general population Psychol Med 35 2005 245 256
32. H.E. Nelson, J.R. Willison The Revised National Adult Reading Test - Test Manual 1991 NFER-Nelson Windsor, United Kingdom
33. E. Bullmore, J. Suckling, F. Zelaya, C. Long, G. Honey, L. Reed Practice and difficulty evoke anatomically and pharmacologically dissociable brain activation dynamics Cereb Cortex 13 2003 144 154
34. C.T. Gualtieri, W. Wargin, R. Kanoy, K. Patrick, C.D. Shen, W. Youngblood Clinical studies of methylphenidate serum levels in children and adults J Am Acad Child Adolesc Psychiatry 21 1982 19 26
35. B.A. Faraj, A.H. Israili, J.M. Perel, M.L. Jenkins, S.G. Holtzman, S.A. Cucinell Metabolism and diposition of methylphenidate -14C: Studies in man and animals J Pharmacol Exp Ther 191 1974 535 547
36. A. Bond, M. Lader The use of analogue scales in rating subjective feelings Br J Med Psychol 47 1974 211 218
37. K. Rubia, A.B. Smith, M.J. Brammer, B. Toone, E. Taylor Abnormal brain activation during inhibition and error detection in medication-naive adolescents with ADHD Am J Psychiatry 162 2005 1067 1075
38. K. Rubia, A.B. Smith, E. Taylor, M. Brammer Linear age-correlated functional development of right inferior fronto-striato-cerebellar networks during response inhibition and anterior cingulate during error-related processes Hum Brain Mapp 28 2007 1163 1177
39. S.R. Chamberlain, A. Hampshire, U. Mueller, K. Rubia, N. del Campo, K. Craig Atomoxetine modulates right inferior frontal activation during inhibitory control: A pharmacological functional magnetic resonance imaging study Biol Psychiatry 65 2009 550 555
40. M. Brett, J.-L. Anton, R. Valabregue, J.-B. Poline Region of interest analysis using an SPM toolbox [abstract] 2002 Paper presented at: 8th International Conference on Functional Mapping of the Human Brain; June 2-6, 2002; Sendai, Japan. Available on CD-ROM in Neuroimage Vol 16, No 2
41. C.N. Boehler, L.G. Appelbaum, R.M. Krebs, J.M. Hopf, M.G. Woldorff Pinning down response inhibition in the brain - conjunction analyses of the stop-signal task Neuroimage 52 2010 1621 1632
42. M. Corbetta, J.M. Kincade, G.L. Shulman Neural systems for visual orienting and their relationships to spatial working memory J Cogn Neurosci 14 2002 508 523
43. S. van Gaal, K.R. Ridderinkhof, W.P.M. van den Wildenberg, V.A.F. Lamme Dissociating consciousness from inhibitory control: Evidence for unconsciously triggered response inhibition in the stop-signal task J Exp Psychol Hum Percept Perform 35 2009 1129 1139
44. P. Dalton, N. Lavie Auditory attentional capture: effects of singleton distractor sounds J Exp Psychol Hum Percept Perform 30 2004 180 193
45. D.J. Mason, G.W. Humphreys, L. Kent Visual search, singleton capture, and the control of attentional set in ADHD Cogn Neuropsychol 21 2004 661 687
46. S.A. Huettel, G. McCarthy What is odd in the oddball task?: Prefrontal cortex is activated by dynamic changes in response strategy Neuropsychologia 42 2004 379 386
47. P. Seeman, B. Madras Methylphenidate elevates resting dopamine which lowers the impulse-triggered release of dopamine: A hypothesis Behav Brain Res 130 2002 79 83
48. H. Graf, B. Abler, R. Freudenmann, P. Beschoner, E. Schaeffeler, M. Spitzer Neural correlates of error monitoring modulated by atomoxetine in healthy volunteers Biol Psychiatry 69 2011 890 897
49. F.P. Bymaster, J.S. Katner, D.L. Nelson, S.K. Hemrick-Luecke, P.G. Threlkeld, J.H. Heiligenstein Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder Neuropsychopharmacology 27 2002 699 711
50. B.L. Schlaggar, T.T. Brown, H.M. Lugar, K.M. Visscher, F.M. Miezin, S.E. Petersen Functional neuroanatomical differences between adults and school-age children in the processing of single words Science 296 2002 1476 1479
51. E.M. Bekker, J.L. Kenemans, M.R. Hoeksma, D. Talsma, M.N. Verbaten The pure electrophysiology of stopping Int J Psychophysiol 55 2005 191 198
52. J.R. Ramautar, H.A. Slagter, A. Kok, K.R. Ridderinkhof Probability effects in the stop-signal paradigm: The insula and the significance of failed inhibition Brain Res 1105 2006 143 154
53. K.R. Ridderinkhof, M. Ullsperger, E.A. Crone, S. Nieuwenhuis The role of the medial frontal cortex in cognitive control Science 306 2004 443 447
54. J. De Fockert, G. Rees, C. Frith, N. Lavie Neural correlates of attentional capture in visual search J Cogn Neurosci 16 2004 751 759
55. B.Y. Hayden, A.C. Nair, A.N. McCoy, M.L. Platt Posterior cingulate cortex mediates outcome-contingent allocation of behavior Neuron 60 2008 19 25
56. S.R. Pliszka, D.C. Glahn, M. Semrud-Clikeman, C. Franklin, R. Perez III, J. Xiong Neuroimaging of inhibitory control areas in children with attention deficit hyperactivity disorder who were treatment naive or in long-term treatment Am J Psychiatry 163 2006 1052 1060
57. C.B. Holroyd, T.E. Baker, K.A. Kerns, U. Müller Electrophysiological evidence of atypical motivation and reward processing in children with attention-deficit hyperactivity disorder Neuropsychologia 46 2008 2234 2242
58. R.M. Alderson, M.D. Rapport, D.E. Sarver, M.J. Kofler ADHD and behavioral inhibition: A re-examination of the stop-signal task J Abnorm Child Psychol 36 2008 989 998
59. D.A. Krusch, R. Klorman, J.T. Brumaghim, P.A. Fitzpatrick, A.D. Borgstedt, J. Strauss Methylphenidate slows reactions of children with attention deficit disorder during and after an error J Abnorm Child Psychol 24 1996 633 650
60. R. Hester, L.S. Nandam, R.G. O'Connell, J. Wagner, M. Strudwick, P.J. Nathan Neurochemical enhancement of conscious error awareness J Neurosci 32 2012 2619 2627
61. Y. Paloyelis, M.A. Mehta, J. Kuntsi, P. Asherson Functional MRI in ADHD: A systematic literature review Expert Rev Neurother 7 2007 1337 1356
62. G. Bush, T.J. Spencer, J. Holmes, L.M. Shin, E.M. Valera, L.J. Seidman Functional magnetic resonance imaging of methylphenidate and placebo in attention-deficit/hyperactivity disorder during the multi-source interference task Arch Gen Psychiatry 65 2008 102 114
63. M. Corbetta, G.L. Shulman Control of goal-directed and stimulus-driven attention in the brain Nat Rev Neurosci 3 2002 201 215