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Volumn 306, Issue 5695, 2004, Pages 443-447

The role of the medial frontal cortex in cognitive control

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIORAL RESEARCH; COGNITIVE SYSTEMS; DEMODULATION; IMAGING TECHNIQUES; NEUROLOGY;

EID: 5644256867     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1100301     Document Type: Review
Times cited : (2423)

References (45)
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    • note
    • Materials and methods are available as supporting material on Science Online.
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    • note
    • The majority of activations fall into the border zone between areas 8, 6, and 32, with some extension into area 24. Recent research in nonhuman primates seems to suggest a functional-anatomical dissociation of regions subserving pre-response conflict monitoring from structures sensitive to errors and omission of reward (1, 4). Although in humans this view is still under debate (77, 73, 21), the present meta-analysis does not provide unequivocal evidence for or against such a dissociation. Activations related to pre-response conflict and uncertainty occur more often in area 8 and less often in area 24 than do signal increases associated with errors and negative feedback (area 8, 32.5% versus 9.7%; area 24, 7.5% versus 25.8%), supporting the dissociation view. However, both groups of activations duster primarily in area 32 (pre-response, 42.5%; error, 41.9%), suggesting that pre- as well as post-response monitoring processes share at least one underlying structure. It seems that the currently available spatial resolution in fMRI, in conjunction with anatomical variability and differences in scanning and preprocessing methods between studies, limit the ability to resolve this debate about a possible dissociation in the range of 10 mm or less.
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    • 0242367944 scopus 로고    scopus 로고
    • H. D. Critchley et al., Brain 126, 2139 (2003).
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    • Critchley, H.D.1
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    • 1142286344 scopus 로고    scopus 로고
    • J. G. Kerns et al., Science 303, 1023 (2004).
    • (2004) Science , vol.303 , pp. 1023
    • Kerns, J.G.1
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    • 0000522258 scopus 로고    scopus 로고
    • R. Parasuraman, Ed. (MIT Press, Cambridge, MA)
    • M. I. Posner, G. J. DiGirolamo, in The Attentive Brain, R. Parasuraman, Ed. (MIT Press, Cambridge, MA, 1998), pp. 401-423.
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    • Posner, M.I.1    DiGirolamo, G.J.2
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    • note
    • This research was supported by a TALENT grant (E.A.C.) and a VENI grant (S.N.) of the Netherlands Organization for Scientific Research and by the Priority Program Executive Functions of the German Research Foundation (M.U.). Helpful comments by S. Bunge are gratefully acknowledged.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.