High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells

Stem Cells

Volumn 30, Issue 7, 2012, Pages 1414-1423

  Turinetto, Valentina ^a   Orlando, Luca ^a,b   Sanchez Ripoll, Yolanda ^b   Kumpfmueller, Benjamin ^b   Storm, Michael P ^b   Porcedda, Paola ^a,c   Minieri, Valentina ^a   Saviozzi, Silvia ^a   Accomasso, Lisa ^a   Rocchietti, Elisa Cibrario ^a   Moorwood, Kim ^b   Circosta, Paola ^a   Cignetti, Alessandro ^a   Welham, Melanie J ^b   Giachino, Claudia ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b University of Bath   (United Kingdom)

^c ISTITUTO NAZIONALE DI RICERCA METROLOGICA   (Italy)

Author keywords

H2AX phosphorylation; Mouse embryonic stem cells; Mouse induced pluripotent stem cells; Self renewal

Indexed keywords

ATM PROTEIN; ATR PROTEIN; DNA DEPENDENT PROTEIN KINASE; HISTONE H2AX; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; EMBRYONIC STEM CELL; HISTONE PHOSPHORYLATION; INNER CELL MASS; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; WILD TYPE;

ANIMALS; DNA DAMAGE; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; HISTONES; INDUCED PLURIPOTENT STEM CELLS; MICE; MICROSCOPY, CONFOCAL; PHOSPHORYLATION;

EID: 84862860070     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1133     Document Type: Article

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