-
1
-
-
69949089944
-
Influence of gender, obesity, and muscle lipase activity on intramyocellular lipids in sedentary individuals
-
Moro C, Galgani JE, Luu L et al. Influence of gender, obesity, and muscle lipase activity on intramyocellular lipids in sedentary individuals. J Clin Endocrinol Metab 2009;94:3440-3447.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 3440-3447
-
-
Moro, C.1
Galgani, J.E.2
Luu, L.3
-
2
-
-
33847332202
-
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
-
Holland WL, Brozinick JT, Wang LP et al. Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance. Cell Metab 2007;5:167-179.
-
(2007)
Cell Metab
, vol.5
, pp. 167-179
-
-
Holland, W.L.1
Brozinick, J.T.2
Wang, L.P.3
-
3
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C, Chen Y, Cline GW et al. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 2002;277:50230-50236.
-
(2002)
J Biol Chem
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
-
4
-
-
77954859197
-
The role of mitochondria in the pathogenesis of type 2 diabetes
-
Patti ME, Corvera S. The role of mitochondria in the pathogenesis of type 2 diabetes. Endocr Rev 2010;31:364-395.
-
(2010)
Endocr Rev
, vol.31
, pp. 364-395
-
-
Patti, M.E.1
Corvera, S.2
-
5
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves TR, Ussher JR, Noland RC et al. Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab 2008;7:45-56.
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
-
6
-
-
21344444333
-
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
-
Sparks LM, Xie H, Koza RA et al. A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 2005;54:1926-1933.
-
(2005)
Diabetes
, vol.54
, pp. 1926-1933
-
-
Sparks, L.M.1
Xie, H.2
Koza, R.A.3
-
8
-
-
0034076660
-
Fuel selection in human skeletal muscle in insulin resistance: A reexamination
-
Kelley DE, Mandarino LJ. Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 2000;49:677-683.
-
(2000)
Diabetes
, vol.49
, pp. 677-683
-
-
Kelley, D.E.1
Mandarino, L.J.2
-
9
-
-
58149379936
-
"Mitochondrial deficiency" does not mediate insulin resistance
-
Holloszy JO. Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance. Am J Clin Nutr 2009;89:463S-466S.
-
(2009)
Am J Clin Nutr
, vol.89
-
-
Holloszy, J.O.1
Muscle, S.2
-
10
-
-
42449089346
-
Metabolic flexibility in response to glucose is not impaired in people with type 2 diabetes after controlling for glucose disposal rate
-
Look AHEAD Adipose Research Group
-
Galgani JE, Heilbronn LK, Azuma K et al.; Look AHEAD Adipose Research Group. Metabolic flexibility in response to glucose is not impaired in people with type 2 diabetes after controlling for glucose disposal rate. Diabetes 2008;57:841-845.
-
(2008)
Diabetes
, vol.57
, pp. 841-845
-
-
Galgani, J.E.1
Heilbronn, L.K.2
Azuma, K.3
-
11
-
-
1442300773
-
UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction
-
Han DH, Nolte LA, Ju JS et al. UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction. Am J Physiol Endocrinol Metab 2004;286: E347-E353.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Han, D.H.1
Nolte, L.A.2
Ju, J.S.3
-
12
-
-
36048931015
-
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal musclepancreatic beta cell crosstalk
-
Handschin C, Choi CS, Chin S et al. Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal musclepancreatic beta cell crosstalk. J Clin Invest 2007;117:3463-3474.
-
(2007)
J Clin Invest
, vol.117
, pp. 3463-3474
-
-
Handschin, C.1
Choi, C.S.2
Chin, S.3
-
13
-
-
33749041269
-
Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance
-
Wredenberg A, Freyer C, Sandström ME et al. Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance. Biochem Biophys Res Commun 2006;350:202-207.
-
(2006)
Biochem Biophys Res Commun
, vol.350
, pp. 202-207
-
-
Wredenberg, A.1
Freyer, C.2
Sandström, M.E.3
-
14
-
-
34047108726
-
Mitochondrial oxidative function and type 2 diabetes
-
Rabøl R, Boushel R, Dela F. Mitochondrial oxidative function and type 2 diabetes. Appl Physiol Nutr Metab 2006;31:675-683.
-
(2006)
Appl Physiol Nutr Metab
, vol.31
, pp. 675-683
-
-
Rabøl, R.1
Boushel, R.2
Dela, F.3
-
15
-
-
0033645223
-
Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise
-
Blaak EE, van Aggel-Leijssen DP, Wagenmakers AJ, Saris WH, van Baak MA. Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise. Diabetes 2000;49:2102-2107.
-
(2000)
Diabetes
, vol.49
, pp. 2102-2107
-
-
Blaak, E.E.1
Van Aggel-Leijssen, D.P.2
Wagenmakers, A.J.3
Saris, W.H.4
Van Baak, M.A.5
-
16
-
-
4344693088
-
Effects of insulin resistance on substrate utilization during exercise in overweight women
-
Braun B, Sharoff C, Chipkin SR, Beaudoin F. Effects of insulin resistance on substrate utilization during exercise in overweight women. J Appl Physiol 2004;97:991-997.
-
(2004)
J Appl Physiol
, vol.97
, pp. 991-997
-
-
Braun, B.1
Sharoff, C.2
Chipkin, S.R.3
Beaudoin, F.4
-
17
-
-
0035514950
-
Plasma free Fatty Acid uptake and oxidation are already diminished in subjects at high risk for developing type 2 diabetes
-
Mensink M, Blaak EE, van Baak MA, Wagenmakers AJ, Saris WH. Plasma free Fatty Acid uptake and oxidation are already diminished in subjects at high risk for developing type 2 diabetes. Diabetes 2001;50:2548-2554.
-
(2001)
Diabetes
, vol.50
, pp. 2548-2554
-
-
Mensink, M.1
Blaak, E.E.2
Van Baak, M.A.3
Wagenmakers, A.J.4
Saris, W.H.5
-
18
-
-
84887212384
-
Metabolic and behavioral compensations in response to caloric restriction: Implications for the maintenance of weight loss
-
Pennington CALERIE Team
-
Redman LM, Heilbronn LK, Martin CK et al.; Pennington CALERIE Team. Metabolic and behavioral compensations in response to caloric restriction: implications for the maintenance of weight loss. PLoS ONE 2009;4:e4377.
-
(2009)
PLoS ONE
, vol.4
-
-
Redman, L.M.1
Heilbronn, L.K.2
Martin, C.K.3
-
19
-
-
0014895192
-
Perceived exertion as an indicator of somatic stress
-
Borg G. Perceived exertion as an indicator of somatic stress. Scand J Rehabil Med 1970;2:92-98.
-
(1970)
Scand J Rehabil Med
, vol.2
, pp. 92-98
-
-
Borg, G.1
-
20
-
-
75549089629
-
Effect of capsinoids on energy metabolism in human subjects
-
Galgani JE, Ryan DH, Ravussin E. Effect of capsinoids on energy metabolism in human subjects. Br J Nutr 2010;103:38-42.
-
(2010)
Br J Nutr
, vol.103
, pp. 38-42
-
-
Galgani, J.E.1
Ryan, D.H.2
Ravussin, E.3
-
21
-
-
0020576146
-
Calculation of substrate oxidation rates in vivo from gaseous exchange
-
Frayn KN. Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 1983;55:628-634.
-
(1983)
J Appl Physiol
, vol.55
, pp. 628-634
-
-
Frayn, K.N.1
-
22
-
-
33847344733
-
Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle
-
Ukropcova B, Sereda O, de Jonge L et al. Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle. Diabetes 2007;56:720-727.
-
(2007)
Diabetes
, vol.56
, pp. 720-727
-
-
Ukropcova, B.1
Sereda, O.2
De Jonge, L.3
-
24
-
-
0033668021
-
Lipid oxidation is reduced in obese human skeletal muscle
-
Kim JY, Hickner RC, Cortright RL, Dohm GL, Houmard JA. Lipid oxidation is reduced in obese human skeletal muscle. Am J Physiol Endocrinol Metab 2000;279:E1039-E1044.
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Kim, J.Y.1
Hickner, R.C.2
Cortright, R.L.3
Dohm, G.L.4
Houmard, J.A.5
-
25
-
-
66149102392
-
Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation
-
Bajpeyi S, Tanner CJ, Slentz CA et al. Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation. J Appl Physiol 2009;106:1079-1085.
-
(2009)
J Appl Physiol
, vol.106
, pp. 1079-1085
-
-
Bajpeyi, S.1
Tanner, C.J.2
Slentz, C.A.3
-
26
-
-
0014968409
-
Mitochondrial citric acid cycle and related enzymes: Adaptive response to exercise
-
Holloszy JO, Oscai LB, Don IJ, Molé PA. Mitochondrial citric acid cycle and related enzymes: adaptive response to exercise. Biochem Biophys Res Commun 1970;40:1368-1373.
-
(1970)
Biochem Biophys Res Commun
, vol.40
, pp. 1368-1373
-
-
Holloszy, J.O.1
Oscai, L.B.2
Don, I.J.3
Molé, P.A.4
-
27
-
-
0028987309
-
Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women
-
Simoneau JA, Colberg SR, Thaete FL, Kelley DE. Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women. FASEB J 1995;9:273-278.
-
(1995)
FASEB J
, vol.9
, pp. 273-278
-
-
Simoneau, J.A.1
Colberg, S.R.2
Thaete, F.L.3
Kelley, D.E.4
-
28
-
-
0033400310
-
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
-
Kelley DE, Goodpaster B, Wing RR, Simoneau JA. Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am J Physiol 1999;277:E1130-E1141.
-
(1999)
Am J Physiol
, vol.277
-
-
Kelley, D.E.1
Goodpaster, B.2
Wing, R.R.3
Simoneau, J.A.4
-
29
-
-
0027946529
-
Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus
-
Kelley DE, Simoneau JA. Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus. J Clin Invest 1994;94:2349-2356.
-
(1994)
J Clin Invest
, vol.94
, pp. 2349-2356
-
-
Kelley, D.E.1
Simoneau, J.A.2
-
30
-
-
47549091170
-
Molecular correlates for maximal oxygen uptake and type 1 fibers
-
Parikh H, Nilsson E, Ling C et al. Molecular correlates for maximal oxygen uptake and type 1 fibers. Am J Physiol Endocrinol Metab 2008;294: E1152-E1159.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Parikh, H.1
Nilsson, E.2
Ling, C.3
-
31
-
-
31044433308
-
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
-
Morino K, Petersen KF, Dufour S et al. Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. J Clin Invest 2005;115:3587-3593.
-
(2005)
J Clin Invest
, vol.115
, pp. 3587-3593
-
-
Morino, K.1
Petersen, K.F.2
Dufour, S.3
-
32
-
-
17844368653
-
Reduced whole-body lipid oxidation is associated with insulin resistance, but not with intramyocellular lipid content in offspring of type 2 diabetic patients
-
Lattuada G, Costantino F, Caumo A et al. Reduced whole-body lipid oxidation is associated with insulin resistance, but not with intramyocellular lipid content in offspring of type 2 diabetic patients. Diabetologia 2005;48:741-747.
-
(2005)
Diabetologia
, vol.48
, pp. 741-747
-
-
Lattuada, G.1
Costantino, F.2
Caumo, A.3
-
33
-
-
0042321037
-
Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity
-
Goodpaster BH, Katsiaras A, Kelley DE. Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity. Diabetes 2003;52:2191-2197.
-
(2003)
Diabetes
, vol.52
, pp. 2191-2197
-
-
Goodpaster, B.H.1
Katsiaras, A.2
Kelley, D.E.3
-
34
-
-
0025047553
-
Skeletal muscle metabolism is a major determinant of resting energy expenditure
-
Zurlo F, Larson K, Bogardus C, Ravussin E. Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest 1990;86:1423-1427.
-
(1990)
J Clin Invest
, vol.86
, pp. 1423-1427
-
-
Zurlo, F.1
Larson, K.2
Bogardus, C.3
Ravussin, E.4
-
35
-
-
77449155964
-
Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes
-
Hwang H, Bowen BP, Lefort N et al. Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes. Diabetes 2010;59:33-42.
-
(2010)
Diabetes
, vol.59
, pp. 33-42
-
-
Hwang, H.1
Bowen, B.P.2
Lefort, N.3
-
36
-
-
34249720640
-
Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes
-
Mogensen M, Sahlin K, Fernström M et al. Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes. Diabetes 2007;56:1592-1599.
-
(2007)
Diabetes
, vol.56
, pp. 1592-1599
-
-
Mogensen, M.1
Sahlin, K.2
Fernström, M.3
-
37
-
-
58149346025
-
Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients
-
Phielix E, Schrauwen-Hinderling VB, Mensink M et al. Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients. Diabetes 2008;57:2943-2949.
-
(2008)
Diabetes
, vol.57
, pp. 2943-2949
-
-
Phielix, E.1
Schrauwen-Hinderling, V.B.2
Mensink, M.3
-
38
-
-
73649100201
-
Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity
-
Ritov VB, Menshikova EV, Azuma K et al. Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity. Am J Physiol Endocrinol Metab 2010;298:E49-E58.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Ritov, V.B.1
Menshikova, E.V.2
Azuma, K.3
-
39
-
-
33845947550
-
Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects
-
Schrauwen-Hinderling VB, Kooi ME, Hesselink MK et al. Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects. Diabetologia 2007;50:113-120.
-
(2007)
Diabetologia
, vol.50
, pp. 113-120
-
-
Schrauwen-Hinderling, V.B.1
Kooi, M.E.2
Hesselink, M.K.3
-
41
-
-
0030854715
-
Cellular energy utilization and molecular origin of standard metabolic rate in mammals
-
Rolfe DF, Brown GC. Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol Rev 1997;77:731-758.
-
(1997)
Physiol Rev
, vol.77
, pp. 731-758
-
-
Rolfe, D.F.1
Brown, G.C.2
-
42
-
-
69249235523
-
Rapid down-regulation of mitochondrial fat metabolism in human muscle after training cessation is dissociated from changes in insulin sensitivity
-
Rimbert V, Vidal H, Duché P et al. Rapid down-regulation of mitochondrial fat metabolism in human muscle after training cessation is dissociated from changes in insulin sensitivity. FEBS Lett 2009;583:2927-2933.
-
(2009)
FEBS Lett
, vol.583
, pp. 2927-2933
-
-
Rimbert, V.1
Vidal, H.2
Duché, P.3
|