B7-H3 participates in the development of experimental pneumococcal meningitis by augmentation of the inflammatory response via a TLR2-dependent mechanism

Journal of Immunology

Volumn 189, Issue 1, 2012, Pages 347-355

  Chen, Xuqin ^a,b   Quinn, Edel M ^a   Ni, Hong ^a   Wang, Jian ^a   Blankson, Siobhan ^b   Redmond, H Paul ^b   Wang, Jiang Huai ^b   Feng, Xing ^a  

^a CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b University College Cork   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN B7 H3; B7 ANTIGEN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B7 H3; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; DRUG TARGETING; ENZYME PHOSPHORYLATION; EXPERIMENTAL MOUSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MICROGLIA; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; PNEUMOCOCCAL MENINGITIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; TRANSCRIPTION INITIATION; UPREGULATION; WILD TYPE;

ANIMALS; B7 ANTIGENS; BLOOD-BRAIN BARRIER; CELLS, CULTURED; INFLAMMATION MEDIATORS; MENINGITIS, PNEUMOCOCCAL; MICE; MICE, INBRED C3H; MICROGLIA; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; TOLL-LIKE RECEPTOR 2;

EID: 84862836740     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103715     Document Type: Article

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