-
1
-
-
78651125802
-
Studies on the constituents of Japanese and Chinese Crude Drugs, XI, Panaxadiol, a sapogenin of ginseng roots
-
S. Shibata, M. Fujita, H. Itokawa, O. Tanako, and T. Ishii Studies on the constituents of Japanese and Chinese Crude Drugs, XI, Panaxadiol, a sapogenin of ginseng roots Chem Pharm Bull (Tokyo) 11 1963 759 761
-
(1963)
Chem Pharm Bull (Tokyo)
, vol.11
, pp. 759-761
-
-
Shibata, S.1
Fujita, M.2
Itokawa, H.3
Tanako, O.4
Ishii, T.5
-
2
-
-
0034521401
-
Steaming of ginseng at high temperature enhances biological activity
-
W.Y. Kim, J.M. Kim, S.B. Han, S.K. Lee, N.D. Kim, and M.K. Park Steaming of ginseng at high temperature enhances biological activity J Nat Prod 63 2000 1702 1704
-
(2000)
J Nat Prod
, vol.63
, pp. 1702-1704
-
-
Kim, W.Y.1
Kim, J.M.2
Han, S.B.3
Lee, S.K.4
Kim, N.D.5
Park, M.K.6
-
7
-
-
65749114119
-
2, not 20(S), is a selective osteoclastgenesis inhibition without any cytotoxicity
-
2, not 20(S), is a selective osteoclastgenesis inhibition without any cytotoxicity Bioorg Med Chem Lett 19 2009 3320 3323
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 3320-3323
-
-
Liu, J.1
Shiono, J.2
Shimizu, K.3
Yu, H.4
Zhang, C.5
Jin, F.6
-
9
-
-
0030838299
-
Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocortocoid receptor
-
Y.J. Lee, E. Chung, K.Y. Lee, Y.H. Lee, B. Huh, and S.K. Lee Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocortocoid receptor Mol Cell Endocrinol 133 1997 135 140
-
(1997)
Mol Cell Endocrinol
, vol.133
, pp. 135-140
-
-
Lee, Y.J.1
Chung, E.2
Lee, K.Y.3
Lee, Y.H.4
Huh, B.5
Lee, S.K.6
-
10
-
-
70449535513
-
1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/AKT/Nrf2-dependent pathway in human dopaminergic cells
-
1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/AKT/Nrf2-dependent pathway in human dopaminergic cells Toxicol Appl Pharmacol 242 2010 18 28
-
(2010)
Toxicol Appl Pharmacol
, vol.242
, pp. 18-28
-
-
Hwang, Y.P.1
Jeong, H.G.2
-
13
-
-
71649112618
-
Rosiglitazone via upregulation of AKT/eNOS pathways attenuates dysfunction of endothelial progenitor cells, induced by advanced glycation end products
-
C. Liang, Y. Ren, H. Tan, Z. He, Q. Jiang, and J. Wu Rosiglitazone via upregulation of AKT/eNOS pathways attenuates dysfunction of endothelial progenitor cells, induced by advanced glycation end products Br J Pharmacol 158 2009 1865 1873
-
(2009)
Br J Pharmacol
, vol.158
, pp. 1865-1873
-
-
Liang, C.1
Ren, Y.2
Tan, H.3
He, Z.4
Jiang, Q.5
Wu, J.6
-
14
-
-
33745424209
-
Peroxisome proliferator-activated receptor-gamma-agonist, rosiglitazone, promotes angiogenesis after focal cerebral ischemia
-
K. Chu, S.T. Lee, J.S. Koo, K.H. Jung, E.H. Kim, and D.I. Sinn Peroxisome proliferator-activated receptor-gamma-agonist, rosiglitazone, promotes angiogenesis after focal cerebral ischemia Brain Res 1093 2006 208 218
-
(2006)
Brain Res
, vol.1093
, pp. 208-218
-
-
Chu, K.1
Lee, S.T.2
Koo, J.S.3
Jung, K.H.4
Kim, E.H.5
Sinn, D.I.6
-
15
-
-
1542652475
-
Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone
-
D. Cho, Y.J. Choi, S.A. Jo, and I. Jo Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone J Biol Chem 279 2004 2499 2506
-
(2004)
J Biol Chem
, vol.279
, pp. 2499-2506
-
-
Cho, D.1
Choi, Y.J.2
Jo, S.A.3
Jo, I.4
-
16
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
J. Folkman Tumor angiogenesis: therapeutic implications N Engl J Med 285 1971 1182 1186
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
17
-
-
33947370773
-
Vascular endothelial (VEGF) signaling in tumor progression
-
R. Roskoski Jr. Vascular endothelial (VEGF) signaling in tumor progression Crit Rev Oncol Hematol 62 2007 179 213
-
(2007)
Crit Rev Oncol Hematol
, vol.62
, pp. 179-213
-
-
Roskoski, Jr.R.1
-
18
-
-
77952326078
-
A simplified method for quantifying cell migration/wound healing in 96-well plates
-
P.Y. Yue, E.P. Leung, N.K. Mak, and R.N. Wong A simplified method for quantifying cell migration/wound healing in 96-well plates J Biomol Screen 15 2010 427 433
-
(2010)
J Biomol Screen
, vol.15
, pp. 427-433
-
-
Yue, P.Y.1
Leung, E.P.2
Mak, N.K.3
Wong, R.N.4
-
20
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
-
R.T. Nolte, G.B. Wisely, S. Westin, J.E. Cobb, M.H. Lambert, and R. Kurokawa Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ Nature 395 1998 137 143
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
Cobb, J.E.4
Lambert, M.H.5
Kurokawa, R.6
-
21
-
-
22144487356
-
Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner
-
Y. Li, M. Choi, K. Suino, A. Kovach, J. Daugherty, and A. Kliewer Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner Proc Natl Acad Sci USA 102 2005 9505 9510
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9505-9510
-
-
Li, Y.1
Choi, M.2
Suino, K.3
Kovach, A.4
Daugherty, J.5
Kliewer, A.6
-
22
-
-
49649094046
-
Structural and biochemical basis for the binding selectivity of peroxisome proliferator-activated receptor γ to PGC-1α
-
Y. Li, A. Kovach, K. Suino-Powell, D. Martynowski, and H.E. Xu Structural and biochemical basis for the binding selectivity of peroxisome proliferator-activated receptor γ to PGC-1α J Biol Chem 283 2008 19132 19139
-
(2008)
J Biol Chem
, vol.283
, pp. 19132-19139
-
-
Li, Y.1
Kovach, A.2
Suino-Powell, K.3
Martynowski, D.4
Xu, H.E.5
-
23
-
-
37349060123
-
The differential interactions of peroxisome proliferator-activated receptor (ligands with Tyr473 is a physical basis for their unique biological activities
-
M. Einstein, T.E. Akiyama, G.A. Castriota, C.F. Wang, B. McKeever, and R.T. Mosley The differential interactions of peroxisome proliferator-activated receptor (ligands with Tyr473 is a physical basis for their unique biological activities Mol Pharmacol 73 2008 62 74
-
(2008)
Mol Pharmacol
, vol.73
, pp. 62-74
-
-
Einstein, M.1
Akiyama, T.E.2
Castriota, G.A.3
Wang, C.F.4
McKeever, B.5
Mosley, R.T.6
-
24
-
-
11644261806
-
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
-
G.M. Morris, D.S. Goodsell, R.S. Halliday, R. Huey, W.E. Hart, and R.K. Belew Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function J Comput Chem 19 1998 1639 1662
-
(1998)
J Comput Chem
, vol.19
, pp. 1639-1662
-
-
Morris, G.M.1
Goodsell, D.S.2
Halliday, R.S.3
Huey, R.4
Hart, W.E.5
Belew, R.K.6
-
25
-
-
34447128782
-
Insights into the mechanism of partial agonism: Crystal structures of the peroxisome proliferator-activated receptor (ligand-binding domain in the complex with two enantiomeric ligands
-
G. Pochetti, C. Godio, N. Mitro, D. Caruso, A. Galmozzi, and S. Scurati Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor (ligand-binding domain in the complex with two enantiomeric ligands J Biol Chem 282 2007 17314 17324
-
(2007)
J Biol Chem
, vol.282
, pp. 17314-17324
-
-
Pochetti, G.1
Godio, C.2
Mitro, N.3
Caruso, D.4
Galmozzi, A.5
Scurati, S.6
-
27
-
-
69049109763
-
2 in PC-3 human xenograft model for prostate cancer in vivo: Formulation, pharmacokinetics, biodistribution and efficacy
-
2 in PC-3 human xenograft model for prostate cancer in vivo: formulation, pharmacokinetics, biodistribution and efficacy Cancer Chemother Pharmacol 64 2009 1085 1095
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 1085-1095
-
-
Musende, A.G.1
Eberding, A.2
Wood, C.3
Adomat, H.4
Fazli, L.5
Hurtado-Coll, A.6
-
29
-
-
37549015237
-
Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia
-
G. Zhang, A. Liu, Y. Zhou, X. San, T. Jin, and Y. Jin Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia J Enthnopharmacol 115 2008 441 448
-
(2008)
J Enthnopharmacol
, vol.115
, pp. 441-448
-
-
Zhang, G.1
Liu, A.2
Zhou, Y.3
San, X.4
Jin, T.5
Jin, Y.6
-
30
-
-
33751574640
-
Drug disposition in three dimensions: An update on stereoselectivity in pharmacokinetics
-
D.R. Brocks Drug disposition in three dimensions: an update on stereoselectivity in pharmacokinetics Biopharm Drug Dispos 127 2008 387 406
-
(2008)
Biopharm Drug Dispos
, vol.127
, pp. 387-406
-
-
Brocks, D.R.1
-
31
-
-
65549171434
-
Stereoselectivity in drug metabolism: Molecular mechanisms and analytical methods
-
V.L. Campo, L.S.C. Bernardes, and I. Carvalho Stereoselectivity in drug metabolism: molecular mechanisms and analytical methods Curr Drug Metab 10 2009 188 205
-
(2009)
Curr Drug Metab
, vol.10
, pp. 188-205
-
-
Campo, V.L.1
Bernardes, L.S.C.2
Carvalho, I.3
-
32
-
-
23744435889
-
Stereochemistry and drug action. Primary care companion
-
J. McConathy, and M.J. Owens Stereochemistry and drug action. Primary care companion J Clin Psychiatry 5 2003 70 73
-
(2003)
J Clin Psychiatry
, vol.5
, pp. 70-73
-
-
McConathy, J.1
Owens, M.J.2
-
33
-
-
0024948937
-
Enantioselective aspects of drug action and disposition: Therapeutic pitfalls
-
F. Jamali, R. Mehvar, and M. Pasutto Enantioselective aspects of drug action and disposition: therapeutic pitfalls J Pharm Sci 78 1989 695 715
-
(1989)
J Pharm Sci
, vol.78
, pp. 695-715
-
-
Jamali, F.1
Mehvar, R.2
Pasutto, M.3
-
35
-
-
34848833429
-
Synthesis, biological evaluation, and molecular modeling investigation of chrial phenoxyacetic acid analogues with PPARalpha and PPARgamma agonist activity
-
G. Fracchiolla, A. Laghezza, L. Piemontese, G. Carbonara, A. Lavecchi, and P. Tortorella Synthesis, biological evaluation, and molecular modeling investigation of chrial phenoxyacetic acid analogues with PPARalpha and PPARgamma agonist activity ChemMedChem 2 2007 641 654
-
(2007)
ChemMedChem
, vol.2
, pp. 641-654
-
-
Fracchiolla, G.1
Laghezza, A.2
Piemontese, L.3
Carbonara, G.4
Lavecchi, A.5
Tortorella, P.6
-
36
-
-
77951785292
-
Measuring binding kinetics of ligands with tethered receptors by fluorescence polarization and total internal reflection fluorescence
-
K. Kwok, and N. Cheung Measuring binding kinetics of ligands with tethered receptors by fluorescence polarization and total internal reflection fluorescence Anal Chem 82 2010 3819 3825
-
(2010)
Anal Chem
, vol.82
, pp. 3819-3825
-
-
Kwok, K.1
Cheung, N.2
-
37
-
-
55949099802
-
2, an endogenous ligand of peroxisome proliferator-activated receptor γ, in tumor angiogenesis
-
2, an endogenous ligand of peroxisome proliferator-activated receptor γ, in tumor angiogenesis Biochem Pharm 76 2008 1544 1553
-
(2008)
Biochem Pharm
, vol.76
, pp. 1544-1553
-
-
Kim, E.1
Surh, Y.2
-
38
-
-
28144454961
-
Ginsenoside Rf a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha
-
H. Lee, F.J. Gonzalez, and M. Yoon Ginsenoside Rf a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha Biochem Biophys Res Commun 339 2006 196 203
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 196-203
-
-
Lee, H.1
Gonzalez, F.J.2
Yoon, M.3
-
40
-
-
29844443744
-
Ginsenoside 20S-protopanaxatriol (PPT) activates peroxisome proliferator-activated receptor gamma (PPARgamma) in 3T3-L1 adipocytes
-
K.L. Han, M.H. Jung, J.H. Sohn, and J.K. Hwang Ginsenoside 20S-protopanaxatriol (PPT) activates peroxisome proliferator-activated receptor gamma (PPARgamma) in 3T3-L1 adipocytes Biol Pharm Bull 29 2006 110 113
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 110-113
-
-
Han, K.L.1
Jung, M.H.2
Sohn, J.H.3
Hwang, J.K.4
-
41
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infraction and death from cardiovascular causes
-
S.E. Nissen, and K. Wolski Effect of rosiglitazone on the risk of myocardial infraction and death from cardiovascular causes N Engl J Med 356 2007 2457 2571
-
(2007)
N Engl J Med
, vol.356
, pp. 2457-2571
-
-
Nissen, S.E.1
Wolski, K.2
-
42
-
-
77956886889
-
3 increases nitric oxide production via increases in phosphorylation and expression of endothelial nitric oxide synthase: Essential roles of estrogen receptor-dependent PI3-kinase and AMP-activated protein kinase
-
3 increases nitric oxide production via increases in phosphorylation and expression of endothelial nitric oxide synthase: essential roles of estrogen receptor-dependent PI3-kinase and AMP-activated protein kinase Toxicol Appl Pharmacol 246 2010 171 183
-
(2010)
Toxicol Appl Pharmacol
, vol.246
, pp. 171-183
-
-
Hien, T.T.1
Kim, N.D.2
Pokharel, Y.R.3
Oh, S.J.4
Lee, M.Y.5
Kang, K.W.6
-
43
-
-
0034730663
-
Bradykinin-regulated interactions of the mitogen-activated protein kinase pathway with the endothelial nitric-oxide synthase
-
S.G. Bernier, S. Haldar, and T. Michel Bradykinin-regulated interactions of the mitogen-activated protein kinase pathway with the endothelial nitric-oxide synthase J Biol Chem 275 2000 30707 30715
-
(2000)
J Biol Chem
, vol.275
, pp. 30707-30715
-
-
Bernier, S.G.1
Haldar, S.2
Michel, T.3
-
44
-
-
34548651801
-
Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells
-
Y.M. Kim, S. Namkoong, Y.G. Yun, H.D. Hong, Y.C. Lee, and K.S. Ha Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells Biol Pharm Bull 30 2007 1674 1679
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 1674-1679
-
-
Kim, Y.M.1
Namkoong, S.2
Yun, Y.G.3
Hong, H.D.4
Lee, Y.C.5
Ha, K.S.6
-
45
-
-
77954244708
-
Peroxisome proliferator-activated receptor gamma (PPAR(): Is the genomic activity the only answer
-
M. Luconi, G. Cantini, and M. Serio Peroxisome proliferator-activated receptor gamma (PPAR(): Is the genomic activity the only answer Steroids 75 2010 585 594
-
(2010)
Steroids
, vol.75
, pp. 585-594
-
-
Luconi, M.1
Cantini, G.2
Serio, M.3
-
46
-
-
42549124085
-
Rosiglitazone induces caveolin-1 by PPARgamma-dependent and PPRE-independent mechanisms: The role of EGF receptor signaling and its effect on cancer cell drug resistance
-
L. Tencer, E. Burgermeister, M.P. Ebert, and M. Liscovitch Rosiglitazone induces caveolin-1 by PPARgamma-dependent and PPRE-independent mechanisms: the role of EGF receptor signaling and its effect on cancer cell drug resistance Anticancer Res 28 2008 895 906
-
(2008)
Anticancer Res
, vol.28
, pp. 895-906
-
-
Tencer, L.1
Burgermeister, E.2
Ebert, M.P.3
Liscovitch, M.4
-
47
-
-
0037428403
-
Peroxisome proliferator-activated receptor gamma (PPARgamma) as a molecular target for the soy phytoestrogen genistein
-
Z.C. Dang, V. Audinot, S.E. Papapoulous, J.A. Boutin, and C.W. Löwik Peroxisome proliferator-activated receptor gamma (PPARgamma) as a molecular target for the soy phytoestrogen genistein J Biol Chem 278 2003 962 967
-
(2003)
J Biol Chem
, vol.278
, pp. 962-967
-
-
Dang, Z.C.1
Audinot, V.2
Papapoulous, S.E.3
Boutin, J.A.4
Löwik, C.W.5
|